| Chrysos, Georgios |
| Recruiting | 3 | 330 | Europe | Clarithromycin 500mg, A β-lactam/β-lactamase inhibitor or a 3rd generation cephalosporin or a fluoroquinolone, Tablets | Hellenic Institute for the Study of Sepsis | Community-acquired Pneumonia | 11/25 | 01/26 | | |
MODIFY, NCT05909683: Assessing the Procalcitonin-guidance and Molecular-guided Diagnosis for Therapy of Severe Infections (the Trial) |
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| Recruiting | 3 | 190 | Europe | Change of antimicrobials based on BCID2 and Reveal Rapid AST tests. Stop of antimicrobials based on PCT results., Standard of Care | Hellenic Institute for the Study of Sepsis | Sepsis | 07/25 | 07/25 | | |
NCT05279352: Safety and Pharmacokinetics of FBR-002 for the Treatment of Patients Hospitalized With COVID-19 in Need of Supplemental Oxygen and at Risk of Severe Outcome |
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| Recruiting | 2a | 30 | Europe | FBR-002, Placebo | Fab'entech | COVID-19 | 06/22 | 07/22 | | |
| Completed | 2 | 44 | Europe | Bezlotoxumab, Standard-of-care treatment according to local guidelines or to the decision of the attending physicians., Normal saline 0.9% or 5% dextrose water, Standard-of-care treatment according to local guidelines or to the decision of the attending physicians | Hellenic Institute for the Study of Sepsis | Clostridioides Difficile Infection, Stool Microbiome, Organ Dysfunction Syndrome, Clostridioides Difficile Infection Recurrence, Mortality | 06/23 | 06/23 | | |
| Metallidis, Simeon |
| Recruiting | 3 | 330 | Europe | Clarithromycin 500mg, A β-lactam/β-lactamase inhibitor or a 3rd generation cephalosporin or a fluoroquinolone, Tablets | Hellenic Institute for the Study of Sepsis | Community-acquired Pneumonia | 11/25 | 01/26 | | |
MODIFY, NCT05909683: Assessing the Procalcitonin-guidance and Molecular-guided Diagnosis for Therapy of Severe Infections (the Trial) |
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| Recruiting | 3 | 190 | Europe | Change of antimicrobials based on BCID2 and Reveal Rapid AST tests. Stop of antimicrobials based on PCT results., Standard of Care | Hellenic Institute for the Study of Sepsis | Sepsis | 07/25 | 07/25 | | |
VOGUE, NCT05979311: A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral Therapy |
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| Recruiting | 3 | 412 | Europe, Japan, RoW | Dolutegravir, Lamivudine, Bictegravir, Emtricitabine, Tenofovir alafenamide | ViiV Healthcare | HIV, HIV Infections | 11/25 | 10/26 | | |
NCT05279352: Safety and Pharmacokinetics of FBR-002 for the Treatment of Patients Hospitalized With COVID-19 in Need of Supplemental Oxygen and at Risk of Severe Outcome |
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| Recruiting | 2a | 30 | Europe | FBR-002, Placebo | Fab'entech | COVID-19 | 06/22 | 07/22 | | |
| Completed | 2 | 1000 | Europe | Anakinra, Kineret | Hellenic Institute for the Study of Sepsis | COVID-19, Virus Diseases, Corona Virus Infection, Lower Respiratory Tract Infection Viral | 01/22 | 04/22 | | |
| Completed | 2 | 44 | Europe | Bezlotoxumab, Standard-of-care treatment according to local guidelines or to the decision of the attending physicians., Normal saline 0.9% or 5% dextrose water, Standard-of-care treatment according to local guidelines or to the decision of the attending physicians | Hellenic Institute for the Study of Sepsis | Clostridioides Difficile Infection, Stool Microbiome, Organ Dysfunction Syndrome, Clostridioides Difficile Infection Recurrence, Mortality | 06/23 | 06/23 | | |
