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18 Trials

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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Friedrich, Jan
MAGNAM, NCT05287191: Trial, Magnesium Versus Amiodarone in Atrial Fibrillation in Critical Care	Recruiting	3	200	Canada	Magnesium sulfate and then Digoxin, Amiodarone	Sunnybrook Health Sciences Centre, Sunnybrook Research Institute	Atrial Fibrillation New Onset	10/25	04/26
FISSH, NCT03677102: Fluids in Septic Shock	Recruiting	2/3	1096	Canada, RoW	higher chloride crystalloid, lower chloride crystalloid	McMaster University, The Physicians' Services Incorporated Foundation, Canadian Institutes of Health Research (CIHR)	Sepsis, Septic Shock	11/25	03/26
InCURS, NCT04176094: Intensive Care Unit Resident Scheduling Trial	Recruiting	N/A	20	Canada	16h overnight duty, 24h overnight duty, Handover training	The Hospital for Sick Children, Sunnybrook Health Sciences Centre	Patient Safety, Well-being, Education	03/26	06/26
ULTIMATE, NCT04832789: Ultra-Low Tidal Volume Mechanical Ventilation in ARDS Through ECMO	Not yet recruiting	N/A	72	Canada, US	Venovenous ECMO	University of Toronto, University Health Network, Toronto	ARDS	06/23	12/23
Burns, Karen EA
FISSH, NCT03677102: Fluids in Septic Shock	Recruiting	2/3	1096	Canada, RoW	higher chloride crystalloid, lower chloride crystalloid	McMaster University, The Physicians' Services Incorporated Foundation, Canadian Institutes of Health Research (CIHR)	Sepsis, Septic Shock	11/25	03/26
CINERGY, NCT05148715: Calcineurin Inhibitor in NEuRoloGically Deceased Donors to Decrease Kidney delaYed Graft Function	Recruiting	2	414	Canada	Tacrolimus, Prograf, Placebo	Université de Sherbrooke, McMaster University	Organ Transplant Failure or Rejection, Brain Death, Ischemic Reperfusion Injury	01/25	01/26
NCT04708509: Extubation Advisor: Initial Implementation and Evaluation of a Novel Extubation Clinical Decision Support Tool	Recruiting	1	72	Canada	Extubation Advisor	Ottawa Hospital Research Institute	Airway Extubation	01/23	02/23
PHENOMANAL, NCT03586089: Phenobarbital for Severe Acute Alcohol Withdrawal Syndrome	Terminated	N/A	8	Canada	Phenobarbital Sodium, Symptom-triggered benzodiazepines (e.g., Valium), Inactive placebo, Symptom triggered benzodiazepines (e.g., Valium)	Unity Health Toronto	Alcohol Withdrawal Delirium, Alcohol Withdrawal, Alcohol Withdrawal Seizures	07/23	07/23
PROMIZING, NCT02447692: Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The Study	Completed	N/A	575	Europe, Canada, RoW	PSV ventilation strategy, PAV+ ventilation strategy	Lawson Health Research Institute, Canadian Institutes of Health Research (CIHR), Medtronic, Canadian Critical Care Trials Group	Critically Ill, Acute Respiratory Failure	07/24	07/24
LEADS, NCT05506904: Liberation From Mechanical Ventilation Using Extubation Advisor Decision Support	Recruiting	N/A	100	Canada	Extubation Advisor	Ottawa Hospital Research Institute	Airway Extubation	03/25	06/25
NCT04061603: iCLAS™ for Persistent Atrial Fibrillation	Active, not recruiting	N/A	200	Europe, Canada, US	Adagio AF Cryoablation System (iCLAS™)	Adagio Medical	Persistent Atrial Fibrillation	08/23	08/24
FAME, NCT05659485: Measuring Family Engagement in Care (The Study)	Recruiting	N/A	198	Canada		Lady Davis Institute, Jewish General Hospital, Canadian Institutes of Health Research (CIHR)	Family Engagement, Patient-centered Care, Critical Care	12/25	12/25
REVIVe, NCT05246098: Frailty, Rehabilitation, and Outcomes in Critically Ill Adult and Pediatric Survivors of COVID-19 or ARI	Recruiting	N/A	900	Canada		McMaster University, Canadian Institutes of Health Research (CIHR), Canadian Critical Care Trials Group	Respiratory Disease, COVID-19, Viral Infection	03/25	10/25
Santos, Marlene S
MAGNAM, NCT05287191: Trial, Magnesium Versus Amiodarone in Atrial Fibrillation in Critical Care	Recruiting	3	200	Canada	Magnesium sulfate and then Digoxin, Amiodarone	Sunnybrook Health Sciences Centre, Sunnybrook Research Institute	Atrial Fibrillation New Onset	10/25	04/26
PROTEST, NCT03559114: PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury	Recruiting	3	1100	Canada	Dalteparin, Fragmin, Saline, Sodium Chloride	Sunnybrook Health Sciences Centre, Sunnybrook Research Institute	Traumatic Brain Injury	12/26	12/27
FISSH, NCT03677102: Fluids in Septic Shock	Recruiting	2/3	1096	Canada, RoW	higher chloride crystalloid, lower chloride crystalloid	McMaster University, The Physicians' Services Incorporated Foundation, Canadian Institutes of Health Research (CIHR)	Sepsis, Septic Shock	11/25	03/26
COLOBILI, NCT04747782: COVID-19 Longitudinal Biomarkers in Lung Injury	Recruiting	N/A	200	Canada	no interventions performed. Just collecting data, blood samples and post-mortem biopsies.	Dr. Andrew Baker	Covid19, Respiratory Disease, Critical Illness	10/21	12/21
McMullen, Sarah
FISSH, NCT03677102: Fluids in Septic Shock	Recruiting	2/3	1096	Canada, RoW	higher chloride crystalloid, lower chloride crystalloid	McMaster University, The Physicians' Services Incorporated Foundation, Canadian Institutes of Health Research (CIHR)	Sepsis, Septic Shock	11/25	03/26