Na Homolce Hospital
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 62 Trials 
119 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Verheye, Stefan
NCT05033964: The DESyne BDS Plus RCT: A Randomized Clinical Trial to Assess the Elixir DESyne BDS Plus Drug Eluting Coronary Stent System for the Treatment of de Novo Native Coronary Artery Lesions

Active, not recruiting
2
200
Europe, RoW
Percutaneous Coronary Intervention with drug eluting stents
Elixir Medical Corporation
Coronary Artery Disease
12/22
03/26
CAPTURE, NCT03571789: Carotid Artery Implant for Trapping Upstream Emboli for Preventing Stroke in Atrial Fibrillation Patients

Active, not recruiting
N/A
25
Europe, RoW
Vine™
Javelin Medical
Atrial Fibrillation
12/18
11/28
BIOSOLVE-IV, NCT02817802: BIOTRONIKS - Safety and Performance in de NOvo Lesion of NatiVE Coronary Arteries With Magmaris- Registry:

Active, not recruiting
N/A
2066
Europe, RoW
Magmaris
Biotronik AG
Coronary Artery Disease
07/20
10/25
NCT04289870: Innoventric Trillium™ Stent Graft First-in-Human (FIH) Study

Active, not recruiting
N/A
20
Europe, RoW
Trillium™
Innoventric LTD
Tricuspid Regurgitation
07/23
06/26
TRICURE, NCT05126030: The First in Human Trial

Recruiting
N/A
20
Europe
Topaz TTVR System
TRiCares
Tricuspid Regurgitation
12/24
05/29
PINNACLE I, NCT05828173: A Clinical Trial to Assess the Elixir Medical LithiX Coronary Hertzian Contact Intravascular Lithotripsy Catheter

Active, not recruiting
N/A
60
Europe
LithiX Coronary Hertzian Contact Intravascular Lithotripsy Catheter (LithiX Coronary HCIVLC; LithiX)
Elixir Medical Corporation
Coronary Artery Disease
04/24
09/24
CAPTURE2, NCT03892824: Carotid Artery Implant for Preventing Stroke in Atrial Fibrillation Patients Taking Oral Anticoagulants

Active, not recruiting
N/A
100
Europe, RoW
Vine™ Embolic Protection System
Javelin Medical, Genae
Atrial Fibrillation, Stroke
11/22
10/24
NCT02710435: REDUCER-I: An Observational Study of the Neovasc Reducer™ System

Active, not recruiting
N/A
400
Europe
Reducer System, Reducer
Neovasc Inc., Shockwave Medical, Inc.
Angina Pectoris, Angina Pectoris, Stable, Chronic Stable Angina
11/23
12/28
NCT04091048: Optimize PRO Study

Active, not recruiting
N/A
800
Europe, Canada, US, RoW
Evolut™ PRO and Evolut™ PRO+ System (Evolut™ FX System for the addendum)
Medtronic Cardiovascular
Symptomatic Aortic Stenosis
12/23
12/24
CHANGE, NCT05853419: Change History and Adopt a Robotic SolutioN for anGioplasty procedurE

Recruiting
N/A
500
Europe, RoW
Robotic-assisted PCI
Robocath, European Cardiovascular Research Center
Coronary Disease
05/26
06/26
Reddy, Vivek Y
MOST, NCT03735979: Multi-arm Optimization of Stroke Thrombolysis

Active, not recruiting
3
514
US
Argatroban, Eptifibatide, Placebo
Washington University School of Medicine, National Institute of Neurological Disorders and Stroke (NINDS)
Acute Ischemic Stroke
12/23
04/25
WAVECREST2, NCT03302494: WAveCrest Vs. Watchman TranssEptal LAA Closure to REduce AF-Mediated STroke 2

Terminated
3
248
US, RoW
Coherex WaveCrest® Left Atrial Appendage Occlusion System, Watchman® LAA Closure Device
Coherex Medical, Biosense Webster, Inc.
Stroke
12/23
12/23
NCT05026866: A Donanemab (LY3002813) Study in Participants With Preclinical Alzheimer's Disease (TRAILBLAZER-ALZ 3)

Active, not recruiting
3
2196
Japan, US
Donanemab, LY3002813, Placebo
Eli Lilly and Company
Alzheimer Disease
11/27
11/27
SISTER, NCT05948566: Strategy for Improving Stroke Treatment Response

Recruiting
2
300
US
TS23
Translational Sciences, Inc., University of Cincinnati, National Institute of Neurological Disorders and Stroke (NINDS), Medical University of South Carolina, University of Arizona
Ischemic Stroke
07/27
12/27
MFAM, NCT03349476: Model Based Fast Anatomical Mapping

Terminated
N/A
109
US
MFAM
Vivek Reddy, Biosense Webster, Inc.
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
10/22
10/22
NCT04358029: Cardiac Arrhythmias In Patients With Coronavirus Disease (COVID-19)

Completed
N/A
4000
US
Vivek Reddy
COVID 19 Cardiac, COVID 16 Arrhythmia, COVID 19 Death
04/23
04/23
ADVENT, NCT04612244: The FARAPULSE PIVOTAL Trial PFA System vs SOC Ablation for Paroxysmal Atrial Fibrillation

Completed
N/A
706
US
FARAPULSE Pulsed Field Ablation System, RadioFrequency and Cryoballoon Ablation
Farapulse, Inc.
Paroxysmal Atrial Fibrillation
05/23
05/23
FULCRUM-VT, NCT05675865: Cryoablation for Monomorphic Ventricular Tachycardia

Recruiting
N/A
206
US
cryoablation procedure
Adagio Medical
Sustained VT
12/25
03/26
LS-PersAFone, NCT06128174: Pulsed Field Ablation for Long-Standing Persistent Atrial Fibrillation

Recruiting
N/A
25
US
Farawave PFA catheter
Vivek Reddy
Long-standing Persistent AF
06/25
06/25
NCT06223789: VOLT-AF IDE Clinical Study

Active, not recruiting
N/A
435
Europe, Canada, US, RoW
Pulsed Field Ablation
Abbott Medical Devices
Atrial Arrhythmia, Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
01/26
01/26
ULTRA-HFIB, NCT04182620: Ultrasound-Based Renal Sympathetic Denervation as Adjunctive Upstream Therapy During Atrial Fibrillation Ablation

Active, not recruiting
N/A
160
US
renal denervation, Catheter ablation
Vivek Reddy
Atrial Fibrillation
03/25
03/25
INTEGRA-D, NCT05855135: Assessment of Combined CCM and ICD Device in HFrEF

Recruiting
N/A
300
US
OPTIMIZER® Integra CCM-D System (Treatment Arm)
Impulse Dynamics
Heart Failure, Heart Failure with Reduced Ejection Fraction, Implantable Defibrillator User, CCM Therapy, Non-ischemic Cardiomyopathy, Ischemic Cardiomyopathy, Sudden Cardiac Arrest, Arrhythmias, Cardiac, Ventricular Tachycardia, Ventricular Fibrillation
06/25
12/25
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Recruiting
N/A
400
Europe, US, RoW
AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
Ancora Heart, Inc.
Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
12/26
12/30

Recruiting
N/A
1857
US
WATCHMAN FLX Pro LAAC Device, WATCHMAN FLX Pro Left Atrial Appendage Closure Device
Boston Scientific Corporation
Atrial Fibrillation, Stroke, Bleeding
07/26
01/27
ADVENT LTO, NCT06526546: ADVENT Trial Long Term Outcomes Evaluating Atrial Fibrillation Progression Study

Enrolling by invitation
N/A
583
US
Boston Scientific Corporation
Paroxysmal Atrial Fibrillation
07/25
10/25
CATALYST, NCT04226547: Amplatzer Amulet LAAO vs. NOAC

Recruiting
N/A
2650
Europe, Canada, Japan, US, RoW
Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC
Abbott Medical Devices
Atrial Fibrillation, Stroke, Bleeding
08/27
08/30
NCT05988411: ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation Vs Control in Redo Ablation Patients

Recruiting
N/A
250
US
Renal Denervation, Catheter Ablation
Vivek Reddy
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
12/27
12/27
VIRTUE, NCT06056557: Versatility of a Circular Multielectrode Catheter in the Individualized Recognition & Treatment of Atrial Fibrillation and Related Arrhythmias Using Pulsed Field Energy

Active, not recruiting
N/A
141
US
VARIPULSE™ catheter ablation
Vivek Reddy
Atrial Fibrillation, Paroxysmal or Persistent, Atrial Fibrillation and Flutter, Atrial Flutter Typical
12/24
12/24
Sphere-9 VT, NCT06703489: Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia

Not yet recruiting
N/A
20
NA
Sphere-9 Catheter with the Affera Mapping and Ablation System
Medtronic Cardiac Rhythm and Heart Failure
Ventricular Tachycardia (VT)
06/25
01/26
ADVANTAGE AF, NCT05443594: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation

Active, not recruiting
N/A
669
Europe, Canada, US
Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System
Boston Scientific Corporation
Persistent Atrial Fibrillation
03/25
03/25
MODULAR ATP, NCT04798768: Effectiveness of the EMPOWER™ Modular Pacing System and EMBLEM™ Subcutaneous ICD to Communicate Antitachycardia Pacing

Active, not recruiting
N/A
297
Europe, Canada, US, RoW
mCRM Therapy System, Communication of S-ICD to Leadless Cardiac Pacemaker (LCP)
Boston Scientific Corporation
Tachycardia, Ventricular, Arrhythmia, Ventricular
03/25
12/30
ASAP-TOO, NCT02928497: Assessment of the WATCHMAN™ Device in Patients Unsuitable for Oral Anticoagulation

Active, not recruiting
N/A
481
Europe, Canada, US, RoW
WATCHMAN LAAC Device Implant, Single Antiplatelet Therapy or No Therapy (Control)
Boston Scientific Corporation
Stroke
12/25
12/25
INTERCEPT, NCT05723926: Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation

Not yet recruiting
N/A
2000
NA
Vine Filter, Vine Embolic Protection System
Javelin Medical, Population Health Research Institute
Atrial Fibrillation, Oral Anticoagulation, Stroke, Implant
12/28
10/30
Burke, Martin
ABCI, NCT05802264: Study to Assess Amphotericin B Cystetic for Inhalation () Doses in Healthy Volunteers & People With Cystic Fibrosis

Recruiting
1
84
RoW
ABCI, Amphotericin B Cystetic for Inhalation, Placebo
Cystetic Medicines, Inc., DevPro Biopharma
Cystic Fibrosis
12/24
12/24
MANAGE-VT, NCT06455488: Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry

Recruiting
N/A
130
US
Ventricular Tachycardia Ablation, ICD Implant, Pacemaker Implant, Antiarrhythmic drug, Statin Therapy, Anticoagulants, EKG, Cardioversion, Echocardiogram
CorVita Science Foundation
Ventricular Tachycardia
07/30
07/30
STEP V, NCT05633394: Subcostal Temporary Extravascular Pacing V Study

Active, not recruiting
N/A
16
RoW
AtaCor StealthTrac Lead
AtaCor Medical, Inc.
Conduction Defect
04/25
05/25
NCT05610033: Pilot evaluatIon Of NovEl tEmpoRary ExtraVascular PACING (PIONEER EV PACING) Study

Active, not recruiting
N/A
30
RoW
AtaCor StealthTrac Lead
AtaCor Medical, Inc.
Conduction Defect
04/25
05/25
NCT05791032: Sub Chronic Evaluation for ATP With an Extravascular Placed ICD Lead (STEP ICD) Study

Completed
N/A
21
RoW
AtaCor EV-ICD Lead
AtaCor Medical, Inc.
Ventricular Arrythmia, Ventricular Tachycardia, Ventricular Fibrillation
02/24
03/24
PRAETORIAN-DFT, NCT03495297: A Randomised Trial of S-ICD Implantation With and Without Defibrillation Testing

Active, not recruiting
N/A
965
Europe, US
ommitence of defibrillation testing
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Boston Scientific Corporation
Ventricular Arrythmia
10/24
10/24
MANAGE-AF, NCT05978466: Registry -MANAGEment of Atrial Fibrillation Outcomes Registry

Recruiting
N/A
1000
US
CorVita Science Foundation
Atrial Fibrillation
12/27
12/27
Neuzil, Petr
CAPTURE, NCT03571789: Carotid Artery Implant for Trapping Upstream Emboli for Preventing Stroke in Atrial Fibrillation Patients

Active, not recruiting
N/A
25
Europe, RoW
Vine™
Javelin Medical
Atrial Fibrillation
12/18
11/28
NCT02909868: CS-03 Pressure-Volume Loop Sub-study With RV Lead Positioning

Active, not recruiting
N/A
15
RoW
BackBeat-PHC
BackBeat Medical Inc
Hypertension
08/21
09/23
FLOW-AF, NCT04473963: A Study to Evaluate the Ablacon Electrographic FLOW EGF Technology

Completed
N/A
85
RoW
Ablamap Software, Ablamap Electrographic Flow Algorithm Technology
Ablacon, Inc.
Atrial Fibrillation, Persistent
09/21
09/21
NCT03700918: First in Human Study of the DaVingi™ TR System in the Treatment of Patients With Functional Tricuspid Regurgitation

Recruiting
N/A
15
Europe, RoW
DaVingiTR System
Cardiac Implants LLC
Functional Tricuspid Regurgitation (TR)
12/21
06/22
EPINAV, NCT04171479: RMN Versus Manual Epicardial Retrospective PMCF

Completed
N/A
40
Europe, RoW
Epicardial mapping and/or ablation
Stereotaxis
Ventricular Tachycardia, Premature Ventricular Contraction
03/23
03/23
NCT04463121: Preload and Autonomic Responses With Cardiac Neuromodulation Therapy (CNT) (CS-06)

Recruiting
N/A
30
RoW
Moderato IPG's CNT pacing signals, CD Leycom Pressure/Volume Combination Catheters
BackBeat Medical Inc, CD Leycom
Bradycardia, Hypertension, Systolic
03/23
07/23
LESS-VT, NCT03490201: FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study

Completed
N/A
592
Europe, US, RoW
Market Approved RF Ablation System, FlexAbility SE Ablation Catheter
Abbott Medical Devices
Ventricular Tachycardia
04/24
04/24
CAPTURE2, NCT03892824: Carotid Artery Implant for Preventing Stroke in Atrial Fibrillation Patients Taking Oral Anticoagulants

Active, not recruiting
N/A
100
Europe, RoW
Vine™ Embolic Protection System
Javelin Medical, Genae
Atrial Fibrillation, Stroke
11/22
10/24
PFA-AF, NCT05113056: AcQForce Pulsed Field Ablation-CE

Completed
N/A
24
RoW
Acutus Medical Pulsed Field Ablation System
Acutus Medical
Atrial Arrhythmia, Atrial Fibrillation
03/23
03/23
NCT05610033: Pilot evaluatIon Of NovEl tEmpoRary ExtraVascular PACING (PIONEER EV PACING) Study

Active, not recruiting
N/A
30
RoW
AtaCor StealthTrac Lead
AtaCor Medical, Inc.
Conduction Defect
04/25
05/25
EASY-R, NCT06388629: Epicardial Access Study With Rook

Recruiting
N/A
40
RoW
Rook Epicardial Access Kit
Circa Scientific, Inc.
Arrythmia
10/24
10/24
C-MIC-II, NCT04662034: Performance and Safety of the Cardiac Microcurrent Therapy System

Completed
N/A
70
Europe, RoW
CMIC, Standard of Care (SOC), Standard drug therapy
Berlin Heals GmbH
Systolic Left Ventricular Dysfunction
11/24
11/24
PARALELL, NCT05408754: Pulsed Field Ablation and Pulsed Field CRyoAbLation in PErsistent AtriaL FibrilLation

Recruiting
N/A
78
Europe, Canada, RoW
Atrial ablation for subject scheduled for a de novo endocardial ablation of symptomatic, drug-refractory PsAF.
Adagio Medical
Atrial Fibrillation
10/24
05/25
NCT06223789: VOLT-AF IDE Clinical Study

Active, not recruiting
N/A
435
Europe, Canada, US, RoW
Pulsed Field Ablation
Abbott Medical Devices
Atrial Arrhythmia, Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
01/26
01/26
VCAS, NCT06203262: Ventricular Catheter Ablation Study

Recruiting
N/A
60
RoW
FieldForce™ Ablation System Ventricular Tachycardia, Pulse Field Ablation, FieldForce™ Ablation System Premature Ventricular Contractions
Field Medical
Ventricular Tachyarrhythmia, Ventricular Arrythmia, PVC - Premature Ventricular Complex, PVC - Premature Ventricular Contraction, Ventricular Tachycardia
04/25
04/25
BEAT PAROX-AF, NCT05159492: Ground-Breaking Electroporation-based Intervention for PAROXysmal Atrial Fibrillation Treatment

Active, not recruiting
N/A
292
Europe, RoW
PVI using PEF, PVI using CFRF
University Hospital, Bordeaux, Funding: European Commission (H2020)
Atrial Fibrillation
02/25
02/25
NCT05272852: PersAFOne III: Feasibility Study of the FARAPULSE Pulsed Field Ablation System Plus - PersAF in the Treatment of Persistent Atrial Fibrillation

Completed
N/A
80
RoW
FARAPULSE™ Pulsed Field Ablation System Plus
Farapulse, Inc.
Persistent Atrial Fibrillation
02/24
02/24
NCT06452589: The Field PULSE Study

Recruiting
N/A
40
RoW
FieldForce Ablation System, Pulse Field Ablation
Field Medical
Atrial Arrhythmias
03/26
06/26
NCT06696170: Evaluation of the CellFX® Nano-Pulsed Field Ablation (PFA) 360 Catheter Endocardial Ablation System for the Treatment of Atrial Fibrillation

Recruiting
N/A
60
RoW
CellFX nano-pFA 360 Endocardial Ablation Catheter System
Pulse Biosciences, Inc.
Atrial Fibrillation Paroxysmal, Cardiac Ablation, Cardiac Arrhythmia
01/26
04/26
BEAT PERS-AF, NCT05418725: Ground-Breaking Electroporation-based Intervention for PERSistent Atrial Fibrillation Treatment

Recruiting
N/A
78
Europe, RoW
PVI and Linear lesion using PEF, PVI and Linear lesion using CFRF
University Hospital, Bordeaux, Horizon 2020 - European Commission
Atrial Fibrillation
05/25
05/25
NCT06580275: The GLACE Study: Evaluating CLAAS With ICE Guided LAA Closure

Recruiting
N/A
80
Europe, RoW
CLAAS
Conformal Medical, Inc
Atrial Fibrillation, Stroke Prevention
06/25
12/25
CATALYST, NCT04226547: Amplatzer Amulet LAAO vs. NOAC

Recruiting
N/A
2650
Europe, Canada, Japan, US, RoW
Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC
Abbott Medical Devices
Atrial Fibrillation, Stroke, Bleeding
08/27
08/30
RESOLVE-AF, NCT05883631: Clinical Evaluation of the Ablacath™ Mapping Catheter and Ablamap® System Utilizing Electrographic Flow (EGF) Mapping to Resolve Extra-PV Sources of Atrial Fibrillation and Guide Ablation Therapy.

Recruiting
N/A
400
Europe, US, RoW
Electrographic Flow (EGF) mapping and ablation of EGF-identified sources of Atrial Fibrillation, OptiMap™ System, Electrographic Flow (EGF) mapping (no ablation)
Cortex, Ablacon, Inc.
Atrial Fibrillation, Atrial Fibrillation, Persistent, Atrial Fibrillation Paroxysmal, Arrhythmia, Arrhythmias, Cardiac, Atrial Flutter, Atrial Fibrillation, Paroxysmal or Persistent, Atrial Arrhythmia, Atrial Tachycardia
03/25
03/25
NCT06048731: Enlighten Study: The EV-ICD Post Approval Registry

Recruiting
N/A
1000
Europe, Canada, US, RoW
Defibrillation using EV-ICD
Medtronic
Ventricular Arrhythmia, Tachycardia
05/30
10/37
Petrossian, George
PERFORMANCE II, NCT04201132: Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System

Active, not recruiting
N/A
305
Europe, US, RoW
Carotid artery stenting with Neuroguard IEP System
Contego Medical, Inc., Yale Cardiovascular Research Group, Advance Research Associates, CardioMed Device Consultants, LLC, Iqvia Pty Ltd, Medidata Solutions
Carotid Artery Stenosis, Carotid Artery Diseases, Carotid Stenosis
10/23
12/25
NCT02661451: Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)

Active, not recruiting
N/A
178
Europe, Canada, US
SAPIEN 3 THV, Optimal Heart Failure Therapy
Cardiovascular Research Foundation, New York, Cardialysis BV, Avania
Aortic Valve Stenosis
02/23
02/25
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Recruiting
N/A
400
Europe, US, RoW
AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
Ancora Heart, Inc.
Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
12/26
12/30
NCT04482062: TRISCEND II Pivotal Trial

Active, not recruiting
N/A
1070
Europe, US
Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy
Edwards Lifesciences
Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure
06/24
12/29
CLASP II TR, NCT04097145: Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

Recruiting
N/A
870
Canada, US
Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy
Edwards Lifesciences
Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease
12/27
12/31
NCT03997305: AltaValve Early Feasibility Study Protocol

Recruiting
N/A
15
US
AltaValve
4C Medical Technologies, Inc.
Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Incompetence, Mitral Valve Regurgitation, Mitral Incompetence
09/25
09/25
CREST-2, NCT02089217: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Active, not recruiting
N/A
2486
Europe, Canada, US, RoW
Carotid endarterectomy (CEA), Carotid Stenting (CAS), Intensive Medical Management - no CEA, Intensive Medical Management - no CAS
Thomas G. Brott, M.D., National Institute of Neurological Disorders and Stroke (NINDS)
Carotid Stenosis
02/26
02/26
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
N/A
1056
Europe, Canada, US
Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Medtronic Cardiovascular
Mitral Valve Regurgitation
10/26
09/36
Walters, Darren
VISTA, NCT05797519: Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation

Recruiting
N/A
40
Europe, RoW
VDyne Transcatheter Tricuspid Valve Replacement System, VDyne System, VDyne Tricuspid System, VDyne Valve System, VDyne Valve
VDyne, Inc.
Tricuspid Regurgitation, Tricuspid Valve Disease, Tricuspid Valvular Disorders
09/25
09/29
Haag, Elizabeth
NCT05143177: A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease with Mild to Moderate Aortic Stenosis (EVOID-AS)

Recruiting
2/3
867
Canada, US
Evogliptin, DA-1229, Placebo
REDNVIA Co., Ltd.
Calcific Aortic Valve Disease
05/26
12/26
OPSENS, NCT03848650: The Drift-Reduction for Improved FFR Using Fiberoptic Technology (DRIFT) Study

Completed
N/A
60
US
OpSens Medical OptoWire, OpSens Medical OptoWire Deux FFR System, FFR, Fractional Flow Reserve
Columbia University
Left Anterior Descending Coronary Artery Stenosis
05/19
05/19
NCT04038944: Anticoagulant and Antiarrhythmic Management Based on Continuous Rhythm Monitoring

Recruiting
N/A
250
US
St. Francis Hospital, New York
New Onset Atrial Fibrillation
07/20
09/23
OPTOCAB, NCT05129228: Optical Coherence Tomography of the Saphenous Vein Graft

Recruiting
N/A
760
US
OCT-guided saphenous vein CABG, ILUMIEN OPTIS NEXT OCT Imaging System, ILUMIEN OPTIS OCT Imaging System, OPTIS Integrated OCT Imaging System, OPTIS Mobile OCT Imaging System, Dragonfly Duo Catheter, Dragonfly OPTIS Catheter, Dragonfly OpStar Imaging Catheter, Dual Channel AureFlo Systems, Coronary Flowprobes
St. Francis Hospital, New York
Coronary Bypass Graft Stenosis
04/24
04/26
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Recruiting
N/A
400
Europe, US, RoW
AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
Ancora Heart, Inc.
Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
12/26
12/30
CHAMPIONSHIP, NCT06410313: First in Human Study to Assess Safety and Efficacy of the ChampioNIR™ Drug Eluting Peripheral Stent in the Treatment of Patients with Superficial Femoral Artery Disease And/or Proximal Popliteal Artery Disease

Recruiting
N/A
30
US, RoW
ChampioNIR Ridaforolimus Eluting Peripheral Stent System
Medinol Ltd.
Superficial Femoral Artery Stenosis, Popliteal Artery Stenosis
08/25
02/28
NCT06523166: Direct Comparison of Cardiac CT With TEE to Evaluate Watchman FLX LAA Occluder Device Characteristics

Not yet recruiting
N/A
320
US
Transesophageal echocardiography (TEE), Cardiac CTA
Steven Filby, MD, Boston Scientific Corporation
Device Related Thrombosis, Peri-device Leak
01/25
01/25
NCT06479824: NHLBI and Cook Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA) Early Feasibility Study

Not yet recruiting
N/A
60
US
TRAIPTA (Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty)
National Heart, Lung, and Blood Institute (NHLBI)
Tricuspid Valve Insufficiency
10/25
09/30
NCT05666713: NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR Trial

Recruiting
N/A
150
US
TELLTALE BASILICA procedure
National Heart, Lung, and Blood Institute (NHLBI)
Valvular Heart Disease, Aortic Valve Failure
01/25
03/25
NCT05787821: Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)

Recruiting
N/A
760
US
Total Knee Arthroplasty
Zimmer Biomet
Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
06/26
06/35
Roxas, Maricel
ADVANCE-DCB, NCT05521542: Advanced NanoTherapies Dual-API DCB to Treat De-Novo Lesions in Patients With Symptomatic Coronary Artery Disease

Recruiting
N/A
40
RoW
SirPlux Duo™ Dual-API Coated PTCA Balloon Catheter
Advanced NanoTherapies, Monash University, Cardiovascular Research Foundation, New York
Coronary Artery Disease
12/24
03/27
AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) Vs Anti-Arrhythmic Drug (AAD) Therapy As a First Line Treatment for Persistent Atrial Fibrillation

Recruiting
N/A
520
Europe, Canada, US, RoW
FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone
Boston Scientific Corporation
Persistent Atrial Fibrillation
12/25
12/27
NCT05425459: RESPONDER-HF Trial

Recruiting
N/A
750
Europe, Canada, US, RoW
Corvia Atrial Shunt System / IASD System II, Intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE)
Corvia Medical
Heart Failure, Heart Failure, Diastolic
05/25
03/31
VISTA, NCT05797519: Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation

Recruiting
N/A
40
Europe, RoW
VDyne Transcatheter Tricuspid Valve Replacement System, VDyne System, VDyne Tricuspid System, VDyne Valve System, VDyne Valve
VDyne, Inc.
Tricuspid Regurgitation, Tricuspid Valve Disease, Tricuspid Valvular Disorders
09/25
09/29
Ostadal, Petr
DAPT-SHOCK-AMI, NCT03551964: Dual Antiplatelet Therapy for Shock Patients with Acute Myocardial Infarction

Active, not recruiting
4
605
Europe, RoW
Cangrelor, intravenous P2Y12 inhibitor, Ticagrelor, oral P2Y12 inhibitor
Faculty Hospital Kralovske Vinohrady, Charles University, Czech Republic
Acute Myocardial Infarction, Cardiogenic Shock
02/24
01/25
Kralovec, Stepan
VCAS, NCT06203262: Ventricular Catheter Ablation Study

Recruiting
N/A
60
RoW
FieldForce™ Ablation System Ventricular Tachycardia, Pulse Field Ablation, FieldForce™ Ablation System Premature Ventricular Contractions
Field Medical
Ventricular Tachyarrhythmia, Ventricular Arrythmia, PVC - Premature Ventricular Complex, PVC - Premature Ventricular Contraction, Ventricular Tachycardia
04/25
04/25
NCT06452589: The Field PULSE Study

Recruiting
N/A
40
RoW
FieldForce Ablation System, Pulse Field Ablation
Field Medical
Atrial Arrhythmias
03/26
06/26
Narayan, Rajeev
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Recruiting
N/A
400
Europe, US, RoW
AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
Ancora Heart, Inc.
Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
12/26
12/30
NCT03142152: The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR

Recruiting
N/A
300
Europe, US
Carillon Mitral Contour System, Carillon, Percutaneous mitral valve repair, Guideline Directed Heart Failure Medication
Cardiac Dimensions, Inc.
Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases
12/26
12/30
Johnson, Tiffany
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Recruiting
N/A
400
Europe, US, RoW
AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
Ancora Heart, Inc.
Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
12/26
12/30
PRECEDE, NCT04970056: Pancreatic Cancer Early Detection Consortium

Recruiting
N/A
10000
Europe, Canada, US, RoW
Arbor Research Collaborative for Health
Pancreas Cancer, Pancreas Cyst, Pancreatic Ductal Adenocarcinoma, Genetic Predisposition
12/30
12/30
Neužil, Petr
SpherePVI, NCT05115214: Safety and Performance of the Affera ™ Multi-Ablation System to Treat Paroxysmal Atrial Fibrillation

Recruiting
N/A
50
RoW
SpherePVI™ Catheter
Affera, Inc.
Atrial Fibrillation
06/25
09/25
NCT05490459: Jewel Electrophysiology (EP) Lab Study

Completed
N/A
18
RoW
Jewel Patch Wearable Cardioverter Defibrillator (P-WCD)
Element Science, Inc.
Sudden Cardiac Arrest
12/22
04/24
NCT05610033: Pilot evaluatIon Of NovEl tEmpoRary ExtraVascular PACING (PIONEER EV PACING) Study

Active, not recruiting
N/A
30
RoW
AtaCor StealthTrac Lead
AtaCor Medical, Inc.
Conduction Defect
04/25
05/25
NCT04893317: Cryoablation for Monomorphic Ventricular Tachycardia (CryoCure-VT)

Active, not recruiting
N/A
64
Europe, Canada, RoW
Ablation in the ventricles with the Adagio Medical VT Cryoablation System
Adagio Medical
Monomorphic Ventricular Tachycardia
06/24
09/24
 

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