Verheye, Stefan |
NCT05033964: The DESyne BDS Plus RCT: A Randomized Clinical Trial to Assess the Elixir DESyne BDS Plus Drug Eluting Coronary Stent System for the Treatment of de Novo Native Coronary Artery Lesions |
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| Active, not recruiting | 2 | 200 | Europe, RoW | Percutaneous Coronary Intervention with drug eluting stents | Elixir Medical Corporation | Coronary Artery Disease | 12/22 | 03/26 | | |
CAPTURE, NCT03571789: Carotid Artery Implant for Trapping Upstream Emboli for Preventing Stroke in Atrial Fibrillation Patients |
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| Active, not recruiting | N/A | 25 | Europe, RoW | Vine™ | Javelin Medical | Atrial Fibrillation | 12/18 | 11/28 | | |
BIOSOLVE-IV, NCT02817802: BIOTRONIKS - Safety and Performance in de NOvo Lesion of NatiVE Coronary Arteries With Magmaris- Registry: |
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| Active, not recruiting | N/A | 2066 | Europe, RoW | Magmaris | Biotronik AG | Coronary Artery Disease | 07/20 | 10/25 | | |
NCT04289870: Innoventric Trillium™ Stent Graft First-in-Human (FIH) Study |
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| Active, not recruiting | N/A | 20 | Europe, RoW | Trillium™ | Innoventric LTD | Tricuspid Regurgitation | 07/23 | 06/26 | | |
| Recruiting | N/A | 20 | Europe | Topaz TTVR System | TRiCares | Tricuspid Regurgitation | 12/24 | 05/29 | | |
PINNACLE I, NCT05828173: A Clinical Trial to Assess the Elixir Medical LithiX Coronary Hertzian Contact Intravascular Lithotripsy Catheter |
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| Active, not recruiting | N/A | 60 | Europe | LithiX Coronary Hertzian Contact Intravascular Lithotripsy Catheter (LithiX Coronary HCIVLC; LithiX) | Elixir Medical Corporation | Coronary Artery Disease | 04/24 | 09/24 | | |
CAPTURE2, NCT03892824: Carotid Artery Implant for Preventing Stroke in Atrial Fibrillation Patients Taking Oral Anticoagulants |
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| Active, not recruiting | N/A | 100 | Europe, RoW | Vine™ Embolic Protection System | Javelin Medical, Genae | Atrial Fibrillation, Stroke | 11/22 | 10/24 | | |
NCT02710435: REDUCER-I: An Observational Study of the Neovasc Reducer™ System |
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| Active, not recruiting | N/A | 400 | Europe | Reducer System, Reducer | Neovasc Inc., Shockwave Medical, Inc. | Angina Pectoris, Angina Pectoris, Stable, Chronic Stable Angina | 11/23 | 12/28 | | |
| Active, not recruiting | N/A | 800 | Europe, Canada, US, RoW | Evolut™ PRO and Evolut™ PRO+ System (Evolut™ FX System for the addendum) | Medtronic Cardiovascular | Symptomatic Aortic Stenosis | 12/23 | 12/24 | | |
| Recruiting | N/A | 500 | Europe, RoW | Robotic-assisted PCI | Robocath, European Cardiovascular Research Center | Coronary Disease | 05/26 | 06/26 | | |
Reddy, Vivek Y |
| Active, not recruiting | 3 | 514 | US | Argatroban, Eptifibatide, Placebo | Washington University School of Medicine, National Institute of Neurological Disorders and Stroke (NINDS) | Acute Ischemic Stroke | 12/23 | 04/25 | | |
| Terminated | 3 | 248 | US, RoW | Coherex WaveCrest® Left Atrial Appendage Occlusion System, Watchman® LAA Closure Device | Coherex Medical, Biosense Webster, Inc. | Stroke | 12/23 | 12/23 | | |
NCT05026866: A Donanemab (LY3002813) Study in Participants With Preclinical Alzheimer's Disease (TRAILBLAZER-ALZ 3) |
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| Active, not recruiting | 3 | 2196 | Japan, US | Donanemab, LY3002813, Placebo | Eli Lilly and Company | Alzheimer Disease | 11/27 | 11/27 | | |
| Recruiting | 2 | 300 | US | TS23 | Translational Sciences, Inc., University of Cincinnati, National Institute of Neurological Disorders and Stroke (NINDS), Medical University of South Carolina, University of Arizona | Ischemic Stroke | 07/27 | 12/27 | | |
| Terminated | N/A | 109 | US | MFAM | Vivek Reddy, Biosense Webster, Inc. | Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation | 10/22 | 10/22 | | |
NCT04358029: Cardiac Arrhythmias In Patients With Coronavirus Disease (COVID-19) |
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| Completed | N/A | 4000 | US | | Vivek Reddy | COVID 19 Cardiac, COVID 16 Arrhythmia, COVID 19 Death | 04/23 | 04/23 | | |
ADVENT, NCT04612244: The FARAPULSE PIVOTAL Trial PFA System vs SOC Ablation for Paroxysmal Atrial Fibrillation |
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| Completed | N/A | 706 | US | FARAPULSE Pulsed Field Ablation System, RadioFrequency and Cryoballoon Ablation | Farapulse, Inc. | Paroxysmal Atrial Fibrillation | 05/23 | 05/23 | | |
| Recruiting | N/A | 206 | US | cryoablation procedure | Adagio Medical | Sustained VT | 12/25 | 03/26 | | |
| Recruiting | N/A | 25 | US | Farawave PFA catheter | Vivek Reddy | Long-standing Persistent AF | 06/25 | 06/25 | | |
| Active, not recruiting | N/A | 435 | Europe, Canada, US, RoW | Pulsed Field Ablation | Abbott Medical Devices | Atrial Arrhythmia, Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation | 01/26 | 01/26 | | |
ULTRA-HFIB, NCT04182620: Ultrasound-Based Renal Sympathetic Denervation as Adjunctive Upstream Therapy During Atrial Fibrillation Ablation |
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| Active, not recruiting | N/A | 160 | US | renal denervation, Catheter ablation | Vivek Reddy | Atrial Fibrillation | 03/25 | 03/25 | | |
| Recruiting | N/A | 300 | US | OPTIMIZER® Integra CCM-D System (Treatment Arm) | Impulse Dynamics | Heart Failure, Heart Failure with Reduced Ejection Fraction, Implantable Defibrillator User, CCM Therapy, Non-ischemic Cardiomyopathy, Ischemic Cardiomyopathy, Sudden Cardiac Arrest, Arrhythmias, Cardiac, Ventricular Tachycardia, Ventricular Fibrillation | 06/25 | 12/25 | | |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
| Recruiting | N/A | 1857 | US | WATCHMAN FLX Pro LAAC Device, WATCHMAN FLX Pro Left Atrial Appendage Closure Device | Boston Scientific Corporation | Atrial Fibrillation, Stroke, Bleeding | 07/26 | 01/27 | | |
| Enrolling by invitation | N/A | 583 | US | | Boston Scientific Corporation | Paroxysmal Atrial Fibrillation | 07/25 | 10/25 | | |
| Recruiting | N/A | 2650 | Europe, Canada, Japan, US, RoW | Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC | Abbott Medical Devices | Atrial Fibrillation, Stroke, Bleeding | 08/27 | 08/30 | | |
NCT05988411: ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation Vs Control in Redo Ablation Patients |
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| Recruiting | N/A | 250 | US | Renal Denervation, Catheter Ablation | Vivek Reddy | Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation | 12/27 | 12/27 | | |
VIRTUE, NCT06056557: Versatility of a Circular Multielectrode Catheter in the Individualized Recognition & Treatment of Atrial Fibrillation and Related Arrhythmias Using Pulsed Field Energy |
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| Active, not recruiting | N/A | 141 | US | VARIPULSE™ catheter ablation | Vivek Reddy | Atrial Fibrillation, Paroxysmal or Persistent, Atrial Fibrillation and Flutter, Atrial Flutter Typical | 12/24 | 12/24 | | |
Sphere-9 VT, NCT06703489: Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia |
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| Not yet recruiting | N/A | 20 | NA | Sphere-9 Catheter with the Affera Mapping and Ablation System | Medtronic Cardiac Rhythm and Heart Failure | Ventricular Tachycardia (VT) | 06/25 | 01/26 | | |
ADVANTAGE AF, NCT05443594: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation |
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| Active, not recruiting | N/A | 669 | Europe, Canada, US | Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System | Boston Scientific Corporation | Persistent Atrial Fibrillation | 03/25 | 03/25 | | |
MODULAR ATP, NCT04798768: Effectiveness of the EMPOWER™ Modular Pacing System and EMBLEM™ Subcutaneous ICD to Communicate Antitachycardia Pacing |
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| Active, not recruiting | N/A | 297 | Europe, Canada, US, RoW | mCRM Therapy System, Communication of S-ICD to Leadless Cardiac Pacemaker (LCP) | Boston Scientific Corporation | Tachycardia, Ventricular, Arrhythmia, Ventricular | 03/25 | 12/30 | | |
| Active, not recruiting | N/A | 481 | Europe, Canada, US, RoW | WATCHMAN LAAC Device Implant, Single Antiplatelet Therapy or No Therapy (Control) | Boston Scientific Corporation | Stroke | 12/25 | 12/25 | | |
INTERCEPT, NCT05723926: Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation |
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| Not yet recruiting | N/A | 2000 | NA | Vine Filter, Vine Embolic Protection System | Javelin Medical, Population Health Research Institute | Atrial Fibrillation, Oral Anticoagulation, Stroke, Implant | 12/28 | 10/30 | | |
Burke, Martin |
ABCI, NCT05802264: Study to Assess Amphotericin B Cystetic for Inhalation () Doses in Healthy Volunteers & People With Cystic Fibrosis |
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| Recruiting | 1 | 84 | RoW | ABCI, Amphotericin B Cystetic for Inhalation, Placebo | Cystetic Medicines, Inc., DevPro Biopharma | Cystic Fibrosis | 12/24 | 12/24 | | |
| Recruiting | N/A | 130 | US | Ventricular Tachycardia Ablation, ICD Implant, Pacemaker Implant, Antiarrhythmic drug, Statin Therapy, Anticoagulants, EKG, Cardioversion, Echocardiogram | CorVita Science Foundation | Ventricular Tachycardia | 07/30 | 07/30 | | |
| Active, not recruiting | N/A | 16 | RoW | AtaCor StealthTrac Lead | AtaCor Medical, Inc. | Conduction Defect | 04/25 | 05/25 | | |
NCT05610033: Pilot evaluatIon Of NovEl tEmpoRary ExtraVascular PACING (PIONEER EV PACING) Study |
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| Active, not recruiting | N/A | 30 | RoW | AtaCor StealthTrac Lead | AtaCor Medical, Inc. | Conduction Defect | 04/25 | 05/25 | | |
NCT05791032: Sub Chronic Evaluation for ATP With an Extravascular Placed ICD Lead (STEP ICD) Study |
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| Completed | N/A | 21 | RoW | AtaCor EV-ICD Lead | AtaCor Medical, Inc. | Ventricular Arrythmia, Ventricular Tachycardia, Ventricular Fibrillation | 02/24 | 03/24 | | |
| Active, not recruiting | N/A | 965 | Europe, US | ommitence of defibrillation testing | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Boston Scientific Corporation | Ventricular Arrythmia | 10/24 | 10/24 | | |
| Recruiting | N/A | 1000 | US | | CorVita Science Foundation | Atrial Fibrillation | 12/27 | 12/27 | | |
Neuzil, Petr |
CAPTURE, NCT03571789: Carotid Artery Implant for Trapping Upstream Emboli for Preventing Stroke in Atrial Fibrillation Patients |
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| Active, not recruiting | N/A | 25 | Europe, RoW | Vine™ | Javelin Medical | Atrial Fibrillation | 12/18 | 11/28 | | |
NCT02909868: CS-03 Pressure-Volume Loop Sub-study With RV Lead Positioning |
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| Active, not recruiting | N/A | 15 | RoW | BackBeat-PHC | BackBeat Medical Inc | Hypertension | 08/21 | 09/23 | | |
| Completed | N/A | 85 | RoW | Ablamap Software, Ablamap Electrographic Flow Algorithm Technology | Ablacon, Inc. | Atrial Fibrillation, Persistent | 09/21 | 09/21 | | |
NCT03700918: First in Human Study of the DaVingi™ TR System in the Treatment of Patients With Functional Tricuspid Regurgitation |
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| Recruiting | N/A | 15 | Europe, RoW | DaVingiTR System | Cardiac Implants LLC | Functional Tricuspid Regurgitation (TR) | 12/21 | 06/22 | | |
| Completed | N/A | 40 | Europe, RoW | Epicardial mapping and/or ablation | Stereotaxis | Ventricular Tachycardia, Premature Ventricular Contraction | 03/23 | 03/23 | | |
NCT04463121: Preload and Autonomic Responses With Cardiac Neuromodulation Therapy (CNT) (CS-06) |
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| Recruiting | N/A | 30 | RoW | Moderato IPG's CNT pacing signals, CD Leycom Pressure/Volume Combination Catheters | BackBeat Medical Inc, CD Leycom | Bradycardia, Hypertension, Systolic | 03/23 | 07/23 | | |
LESS-VT, NCT03490201: FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study |
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| Completed | N/A | 592 | Europe, US, RoW | Market Approved RF Ablation System, FlexAbility SE Ablation Catheter | Abbott Medical Devices | Ventricular Tachycardia | 04/24 | 04/24 | | |
CAPTURE2, NCT03892824: Carotid Artery Implant for Preventing Stroke in Atrial Fibrillation Patients Taking Oral Anticoagulants |
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| Active, not recruiting | N/A | 100 | Europe, RoW | Vine™ Embolic Protection System | Javelin Medical, Genae | Atrial Fibrillation, Stroke | 11/22 | 10/24 | | |
| Completed | N/A | 24 | RoW | Acutus Medical Pulsed Field Ablation System | Acutus Medical | Atrial Arrhythmia, Atrial Fibrillation | 03/23 | 03/23 | | |
NCT05610033: Pilot evaluatIon Of NovEl tEmpoRary ExtraVascular PACING (PIONEER EV PACING) Study |
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| Active, not recruiting | N/A | 30 | RoW | AtaCor StealthTrac Lead | AtaCor Medical, Inc. | Conduction Defect | 04/25 | 05/25 | | |
| Recruiting | N/A | 40 | RoW | Rook Epicardial Access Kit | Circa Scientific, Inc. | Arrythmia | 10/24 | 10/24 | | |
| Completed | N/A | 70 | Europe, RoW | CMIC, Standard of Care (SOC), Standard drug therapy | Berlin Heals GmbH | Systolic Left Ventricular Dysfunction | 11/24 | 11/24 | | |
| Recruiting | N/A | 78 | Europe, Canada, RoW | Atrial ablation for subject scheduled for a de novo endocardial ablation of symptomatic, drug-refractory PsAF. | Adagio Medical | Atrial Fibrillation | 10/24 | 05/25 | | |
| Active, not recruiting | N/A | 435 | Europe, Canada, US, RoW | Pulsed Field Ablation | Abbott Medical Devices | Atrial Arrhythmia, Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation | 01/26 | 01/26 | | |
| Recruiting | N/A | 60 | RoW | FieldForce™ Ablation System Ventricular Tachycardia, Pulse Field Ablation, FieldForce™ Ablation System Premature Ventricular Contractions | Field Medical | Ventricular Tachyarrhythmia, Ventricular Arrythmia, PVC - Premature Ventricular Complex, PVC - Premature Ventricular Contraction, Ventricular Tachycardia | 04/25 | 04/25 | | |
| Active, not recruiting | N/A | 292 | Europe, RoW | PVI using PEF, PVI using CFRF | University Hospital, Bordeaux, Funding: European Commission (H2020) | Atrial Fibrillation | 02/25 | 02/25 | | |
NCT05272852: PersAFOne III: Feasibility Study of the FARAPULSE Pulsed Field Ablation System Plus - PersAF in the Treatment of Persistent Atrial Fibrillation |
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| Completed | N/A | 80 | RoW | FARAPULSE™ Pulsed Field Ablation System Plus | Farapulse, Inc. | Persistent Atrial Fibrillation | 02/24 | 02/24 | | |
| Recruiting | N/A | 40 | RoW | FieldForce Ablation System, Pulse Field Ablation | Field Medical | Atrial Arrhythmias | 03/26 | 06/26 | | |
NCT06696170: Evaluation of the CellFX® Nano-Pulsed Field Ablation (PFA) 360 Catheter Endocardial Ablation System for the Treatment of Atrial Fibrillation |
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| Recruiting | N/A | 60 | RoW | CellFX nano-pFA 360 Endocardial Ablation Catheter System | Pulse Biosciences, Inc. | Atrial Fibrillation Paroxysmal, Cardiac Ablation, Cardiac Arrhythmia | 01/26 | 04/26 | | |
| Recruiting | N/A | 78 | Europe, RoW | PVI and Linear lesion using PEF, PVI and Linear lesion using CFRF | University Hospital, Bordeaux, Horizon 2020 - European Commission | Atrial Fibrillation | 05/25 | 05/25 | | |
NCT06580275: The GLACE Study: Evaluating CLAAS With ICE Guided LAA Closure |
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| Recruiting | N/A | 80 | Europe, RoW | CLAAS | Conformal Medical, Inc | Atrial Fibrillation, Stroke Prevention | 06/25 | 12/25 | | |
| Recruiting | N/A | 2650 | Europe, Canada, Japan, US, RoW | Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC | Abbott Medical Devices | Atrial Fibrillation, Stroke, Bleeding | 08/27 | 08/30 | | |
RESOLVE-AF, NCT05883631: Clinical Evaluation of the Ablacath™ Mapping Catheter and Ablamap® System Utilizing Electrographic Flow (EGF) Mapping to Resolve Extra-PV Sources of Atrial Fibrillation and Guide Ablation Therapy. |
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| Recruiting | N/A | 400 | Europe, US, RoW | Electrographic Flow (EGF) mapping and ablation of EGF-identified sources of Atrial Fibrillation, OptiMap™ System, Electrographic Flow (EGF) mapping (no ablation) | Cortex, Ablacon, Inc. | Atrial Fibrillation, Atrial Fibrillation, Persistent, Atrial Fibrillation Paroxysmal, Arrhythmia, Arrhythmias, Cardiac, Atrial Flutter, Atrial Fibrillation, Paroxysmal or Persistent, Atrial Arrhythmia, Atrial Tachycardia | 03/25 | 03/25 | | |
NCT06048731: Enlighten Study: The EV-ICD Post Approval Registry |
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| Recruiting | N/A | 1000 | Europe, Canada, US, RoW | Defibrillation using EV-ICD | Medtronic | Ventricular Arrhythmia, Tachycardia | 05/30 | 10/37 | | |
Petrossian, George |
| Active, not recruiting | N/A | 305 | Europe, US, RoW | Carotid artery stenting with Neuroguard IEP System | Contego Medical, Inc., Yale Cardiovascular Research Group, Advance Research Associates, CardioMed Device Consultants, LLC, Iqvia Pty Ltd, Medidata Solutions | Carotid Artery Stenosis, Carotid Artery Diseases, Carotid Stenosis | 10/23 | 12/25 | | |
NCT02661451: Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD) |
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| Active, not recruiting | N/A | 178 | Europe, Canada, US | SAPIEN 3 THV, Optimal Heart Failure Therapy | Cardiovascular Research Foundation, New York, Cardialysis BV, Avania | Aortic Valve Stenosis | 02/23 | 02/25 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
| Active, not recruiting | N/A | 1070 | Europe, US | Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure | 06/24 | 12/29 | | |
| Recruiting | N/A | 870 | Canada, US | Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease | 12/27 | 12/31 | | |
| Recruiting | N/A | 15 | US | AltaValve | 4C Medical Technologies, Inc. | Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Incompetence, Mitral Valve Regurgitation, Mitral Incompetence | 09/25 | 09/25 | | |
CREST-2, NCT02089217: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial |
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| Active, not recruiting | N/A | 2486 | Europe, Canada, US, RoW | Carotid endarterectomy (CEA), Carotid Stenting (CAS), Intensive Medical Management - no CEA, Intensive Medical Management - no CAS | Thomas G. Brott, M.D., National Institute of Neurological Disorders and Stroke (NINDS) | Carotid Stenosis | 02/26 | 02/26 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MitraClip™ device implantation, Mitral Valve Repair Surgery | Abbott Medical Devices | Mitral Valve Regurgitation | 04/26 | 04/34 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
Walters, Darren |
VISTA, NCT05797519: Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation |
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| Recruiting | N/A | 40 | Europe, RoW | VDyne Transcatheter Tricuspid Valve Replacement System, VDyne System, VDyne Tricuspid System, VDyne Valve System, VDyne Valve | VDyne, Inc. | Tricuspid Regurgitation, Tricuspid Valve Disease, Tricuspid Valvular Disorders | 09/25 | 09/29 | | |
Haag, Elizabeth |
NCT05143177: A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease with Mild to Moderate Aortic Stenosis (EVOID-AS) |
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| Recruiting | 2/3 | 867 | Canada, US | Evogliptin, DA-1229, Placebo | REDNVIA Co., Ltd. | Calcific Aortic Valve Disease | 05/26 | 12/26 | | |
| Completed | N/A | 60 | US | OpSens Medical OptoWire, OpSens Medical OptoWire Deux FFR System, FFR, Fractional Flow Reserve | Columbia University | Left Anterior Descending Coronary Artery Stenosis | 05/19 | 05/19 | | |
NCT04038944: Anticoagulant and Antiarrhythmic Management Based on Continuous Rhythm Monitoring |
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| Recruiting | N/A | 250 | US | | St. Francis Hospital, New York | New Onset Atrial Fibrillation | 07/20 | 09/23 | | |
| Recruiting | N/A | 760 | US | OCT-guided saphenous vein CABG, ILUMIEN OPTIS NEXT OCT Imaging System, ILUMIEN OPTIS OCT Imaging System, OPTIS Integrated OCT Imaging System, OPTIS Mobile OCT Imaging System, Dragonfly Duo Catheter, Dragonfly OPTIS Catheter, Dragonfly OpStar Imaging Catheter, Dual Channel AureFlo Systems, Coronary Flowprobes | St. Francis Hospital, New York | Coronary Bypass Graft Stenosis | 04/24 | 04/26 | | |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
CHAMPIONSHIP, NCT06410313: First in Human Study to Assess Safety and Efficacy of the ChampioNIR™ Drug Eluting Peripheral Stent in the Treatment of Patients with Superficial Femoral Artery Disease And/or Proximal Popliteal Artery Disease |
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| Recruiting | N/A | 30 | US, RoW | ChampioNIR Ridaforolimus Eluting Peripheral Stent System | Medinol Ltd. | Superficial Femoral Artery Stenosis, Popliteal Artery Stenosis | 08/25 | 02/28 | | |
NCT06523166: Direct Comparison of Cardiac CT With TEE to Evaluate Watchman FLX LAA Occluder Device Characteristics |
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| Not yet recruiting | N/A | 320 | US | Transesophageal echocardiography (TEE), Cardiac CTA | Steven Filby, MD, Boston Scientific Corporation | Device Related Thrombosis, Peri-device Leak | 01/25 | 01/25 | | |
NCT06479824: NHLBI and Cook Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA) Early Feasibility Study |
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| Not yet recruiting | N/A | 60 | US | TRAIPTA (Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty) | National Heart, Lung, and Blood Institute (NHLBI) | Tricuspid Valve Insufficiency | 10/25 | 09/30 | | |
NCT05666713: NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR Trial |
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| Recruiting | N/A | 150 | US | TELLTALE BASILICA procedure | National Heart, Lung, and Blood Institute (NHLBI) | Valvular Heart Disease, Aortic Valve Failure | 01/25 | 03/25 | | |
NCT05787821: Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty) |
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| Recruiting | N/A | 760 | US | Total Knee Arthroplasty | Zimmer Biomet | Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis | 06/26 | 06/35 | | |
Roxas, Maricel |
ADVANCE-DCB, NCT05521542: Advanced NanoTherapies Dual-API DCB to Treat De-Novo Lesions in Patients With Symptomatic Coronary Artery Disease |
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| Recruiting | N/A | 40 | RoW | SirPlux Duo™ Dual-API Coated PTCA Balloon Catheter | Advanced NanoTherapies, Monash University, Cardiovascular Research Foundation, New York | Coronary Artery Disease | 12/24 | 03/27 | | |
AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) Vs Anti-Arrhythmic Drug (AAD) Therapy As a First Line Treatment for Persistent Atrial Fibrillation |
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| Recruiting | N/A | 520 | Europe, Canada, US, RoW | FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone | Boston Scientific Corporation | Persistent Atrial Fibrillation | 12/25 | 12/27 | | |
| Recruiting | N/A | 750 | Europe, Canada, US, RoW | Corvia Atrial Shunt System / IASD System II, Intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE) | Corvia Medical | Heart Failure, Heart Failure, Diastolic | 05/25 | 03/31 | | |
VISTA, NCT05797519: Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation |
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| Recruiting | N/A | 40 | Europe, RoW | VDyne Transcatheter Tricuspid Valve Replacement System, VDyne System, VDyne Tricuspid System, VDyne Valve System, VDyne Valve | VDyne, Inc. | Tricuspid Regurgitation, Tricuspid Valve Disease, Tricuspid Valvular Disorders | 09/25 | 09/29 | | |
Ostadal, Petr |
| Active, not recruiting | 4 | 605 | Europe, RoW | Cangrelor, intravenous P2Y12 inhibitor, Ticagrelor, oral P2Y12 inhibitor | Faculty Hospital Kralovske Vinohrady, Charles University, Czech Republic | Acute Myocardial Infarction, Cardiogenic Shock | 02/24 | 01/25 | | |
Kralovec, Stepan |
| Recruiting | N/A | 60 | RoW | FieldForce™ Ablation System Ventricular Tachycardia, Pulse Field Ablation, FieldForce™ Ablation System Premature Ventricular Contractions | Field Medical | Ventricular Tachyarrhythmia, Ventricular Arrythmia, PVC - Premature Ventricular Complex, PVC - Premature Ventricular Contraction, Ventricular Tachycardia | 04/25 | 04/25 | | |
| Recruiting | N/A | 40 | RoW | FieldForce Ablation System, Pulse Field Ablation | Field Medical | Atrial Arrhythmias | 03/26 | 06/26 | | |
Narayan, Rajeev |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
NCT03142152: The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR |
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| Recruiting | N/A | 300 | Europe, US | Carillon Mitral Contour System, Carillon, Percutaneous mitral valve repair, Guideline Directed Heart Failure Medication | Cardiac Dimensions, Inc. | Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases | 12/26 | 12/30 | | |
Johnson, Tiffany |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
| Recruiting | N/A | 10000 | Europe, Canada, US, RoW | | Arbor Research Collaborative for Health | Pancreas Cancer, Pancreas Cyst, Pancreatic Ductal Adenocarcinoma, Genetic Predisposition | 12/30 | 12/30 | | |
Neužil, Petr |
SpherePVI, NCT05115214: Safety and Performance of the Affera ™ Multi-Ablation System to Treat Paroxysmal Atrial Fibrillation |
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| Recruiting | N/A | 50 | RoW | SpherePVI™ Catheter | Affera, Inc. | Atrial Fibrillation | 06/25 | 09/25 | | |
| Completed | N/A | 18 | RoW | Jewel Patch Wearable Cardioverter Defibrillator (P-WCD) | Element Science, Inc. | Sudden Cardiac Arrest | 12/22 | 04/24 | | |
NCT05610033: Pilot evaluatIon Of NovEl tEmpoRary ExtraVascular PACING (PIONEER EV PACING) Study |
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| Active, not recruiting | N/A | 30 | RoW | AtaCor StealthTrac Lead | AtaCor Medical, Inc. | Conduction Defect | 04/25 | 05/25 | | |
NCT04893317: Cryoablation for Monomorphic Ventricular Tachycardia (CryoCure-VT) |
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| Active, not recruiting | N/A | 64 | Europe, Canada, RoW | Ablation in the ventricles with the Adagio Medical VT Cryoablation System | Adagio Medical | Monomorphic Ventricular Tachycardia | 06/24 | 09/24 | | |