Calhoun, William |
| Active, not recruiting | 4 | 2476 | US | High dose potent statin, atorvastatin or rosuvastatin, ACE-I (lisinopril) or ARB (losartan), ACE-I or ARB, Aspirin, Lifestyle Counseling, PACE Lifestyle Intervention, Quality of Life Questionnaires, QOL | University of Florida, United States Department of Defense | Coronary Artery Disease | 09/24 | 12/24 | | |
| Recruiting | 2 | 75 | US | Research Grade RG-RV | The University of Texas Medical Branch, Galveston, Mohammad Zaidan, MD | Asthma, Allergic Rhinitis, Cat Allergy, Healthy | 05/27 | 05/27 | | |
Stone, James |
NCT04680026: A Study of IV HBI-3000 for the Conversion Recent Onset Atrial Fibrillation (AF) |
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| Active, not recruiting | 2 | 150 | Canada, US, RoW | HBI-3000, sulcardine sulfate, Placebo | HUYABIO International, LLC. | Atrial Fibrillation | 12/24 | 12/24 | | |
C-TRACT, NCT03250247: Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The Trial) |
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| Recruiting | N/A | 250 | US | Stents | Washington University School of Medicine, Ontario Clinical Oncology Group (OCOG), Massachusetts General Hospital, Saint Luke's Mid America Heart Institute | Deep Vein Thrombosis, Venous Stasis, Venous Insufficiency, Venous Leg Ulcer, Venous Reflux, Post Thrombotic Syndrome | 01/26 | 04/26 | | |
NCT04190186: Hybrid Ablation Plus Medical Therapy for Persistent Atrial Fibrillation |
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| Completed | N/A | 55 | US | Insertable Cardiac Monitor, BioMonitor3® or future generation of Biotronik ICM | University of Rochester, Biotronik, Inc. | Persistent Atrial Fibrillation | 02/24 | 02/24 | | |
NCT03643224: DiamondTemp™ System for the Treatment of Persistent Atrial Fibrillation |
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| Completed | N/A | 376 | Europe, Canada, US, RoW | Radiofrequency Ablation | Medtronic Cardiac Rhythm and Heart Failure | Persistent Atrial Fibrillation, Atrial Fibrillation | 10/24 | 10/24 | | |
Bertolet, Barry |
VICTORION-2P, NCT05030428: Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease |
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| Active, not recruiting | 3 | 17004 | Europe, Canada, Japan, US, RoW | Inclisiran sodium 300 mg, Placebo | Novartis Pharmaceuticals | Atherosclerotic Cardiovascular Disease | 10/27 | 10/27 | | |
| Recruiting | 3 | 14000 | Europe, Canada, US, RoW | Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL, KJX839, Placebo in 1.5ml | Novartis Pharmaceuticals | Primary Prevention of Atherosclerotic Cardiovascular Disease | 03/29 | 03/29 | | |
NCT05562934: An Efficacy, Safety, Tolerability and Dose Finding Study of XXB750 in Resistant Hypertension Patients. |
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| Completed | 2 | 194 | Europe, Japan, US, RoW | Experimental drug, Placebo | Novartis Pharmaceuticals | Resistant Hypertension | 07/24 | 08/24 | | |
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN |
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| Recruiting | N/A | 1400 | Europe, US, RoW | Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation | Medtronic Vascular | Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus | 11/26 | 11/29 | | |
| Active, not recruiting | N/A | 75 | US | Intravascular Lithotripsy | Shockwave Medical, Inc. | Peripheral Arterial Disease | 04/24 | 04/25 | | |
| Active, not recruiting | N/A | 826 | US | Reveal LINQ™ Insertable Cardiac Monitor with investigational ALLEVIATE-HF RAMware download, Medication intervention | Medtronic Cardiac Rhythm and Heart Failure | Heart Failure NYHA Class II, Heart Failure NYHA Class III | 05/25 | 05/25 | | |
| Recruiting | N/A | 492 | US | Sirolimus Drug Coated Balloon, Plan balloon Angioplasty (POBA) | Concept Medical Inc., Cardiovascular Research Foundation, New York | In-Stent Restenosis, Cardiovascular Diseases, Coronary Artery Disease | 09/25 | 02/28 | | |
LUX-Dx TRENDS, NCT04790344: Evaluates Diagnostics Sensors in Heart Failure Patients Receiving Boston Scientific's Investigational ICM System. |
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| Active, not recruiting | N/A | 525 | US | Investigational LUX-Dx ICM Implant | Boston Scientific Corporation | Heart Failure | 05/26 | 06/26 | | |
| Recruiting | N/A | 5000 | Europe, Canada, US, RoW | Any eligible commercially available Boston Scientific Corporation (BSC) drug-eluting device. | Boston Scientific Corporation | Peripheral Vascular Diseases | 01/28 | 01/28 | | |
Stein, Bernardo |
| Recruiting | N/A | 492 | US | Sirolimus Drug Coated Balloon, Plan balloon Angioplasty (POBA) | Concept Medical Inc., Cardiovascular Research Foundation, New York | In-Stent Restenosis, Cardiovascular Diseases, Coronary Artery Disease | 09/25 | 02/28 | | |
Ray, Yvonne |
NCT04680026: A Study of IV HBI-3000 for the Conversion Recent Onset Atrial Fibrillation (AF) |
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| Active, not recruiting | 2 | 150 | Canada, US, RoW | HBI-3000, sulcardine sulfate, Placebo | HUYABIO International, LLC. | Atrial Fibrillation | 12/24 | 12/24 | | |
| Recruiting | N/A | 380 | Canada, US | Arm 1: treatment with Neovasc Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry | Neovasc Inc., Shockwave Medical, Inc. | Refractory Angina | 06/25 | 12/28 | | |
NCT04190186: Hybrid Ablation Plus Medical Therapy for Persistent Atrial Fibrillation |
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| Completed | N/A | 55 | US | Insertable Cardiac Monitor, BioMonitor3® or future generation of Biotronik ICM | University of Rochester, Biotronik, Inc. | Persistent Atrial Fibrillation | 02/24 | 02/24 | | |
| Recruiting | N/A | 1500 | US | Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System, CCM Group (CCM ON), OPTIMIZER™ Smart Mini System, Sham Group (CCM OFF) | Impulse Dynamics | Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction, Heart Failure With Moderately Reduced Ejection Fraction, Diastolic Heart Failure | 02/25 | 02/26 | | |
Watts, Tina |
| Active, not recruiting | 4 | 2476 | US | High dose potent statin, atorvastatin or rosuvastatin, ACE-I (lisinopril) or ARB (losartan), ACE-I or ARB, Aspirin, Lifestyle Counseling, PACE Lifestyle Intervention, Quality of Life Questionnaires, QOL | University of Florida, United States Department of Defense | Coronary Artery Disease | 09/24 | 12/24 | | |