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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
El-Hamdani, Mehiar
REAL, NCT05156996: A Prospective Real-World Multi-Center Post-Market Observational Evaluation of Supersaturated O2 Therapy Using the TherOx® Downstream® System	Terminated	N/A	6	US	Supersaturated O2 Therapy of the Therox Downstream System®, PCI alone	TherOx	Anterior Acute Myocardial Infarction (AMI)	01/24	04/24
SSCORE, NCT06438315: SuperSaturated Oxygen Comprehensive Observational Registry	Recruiting	N/A	1000	US	No intervention	TherOx	STEMI - ST Elevation Myocardial Infarction, AMI	03/27	03/29
Marcum, Melissa
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy	Recruiting	N/A	620	US	OPTIMIZER Smart System	Impulse Dynamics	Heart Failure	03/26	03/26