| O'Dwyer, Peter J |
NCT02471170: Protocol to Permit the Acquisition of Circulating Tumor Material in Pancreatic Diseases |
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| Enrolling by invitation | N/A | 100 | US | | Abramson Cancer Center at Penn Medicine | Pancreatic Diseases | 01/25 | 01/25 | | |
| Carey, James R |
NCT02771496: Osteochondritis Dissecans of Knee Prospective Cohort |
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| Active, not recruiting | N/A | 3000 | US | Other: observational only- no intervention | University of Pennsylvania, Altona Children's Hospital, Boston Children's Hospital, Children's Hospital Medical Center, Cincinnati, Children's Health Andrews Institute for Orthopaedics & Sports Medicine, Children's Healthcare of Atlanta, Children's Hospital Colorado, Children's Hospital of Philadelphia, Children's Hospital and Health System Foundation, Wisconsin, Children's Mercy Hospital Kansas City, Connecticut Children's Medical Center, Hospital for Special Surgery, New York, Kaiser Permanente, Mayo Clinic, National University Hospital, Singapore, Rady Children's Hospital, San Diego, Stanford University, Tennessee Orthopedic Alliance, Texas Scottish Rite Hospital for Children, The Rocky Mountain Hospital for Children, The Hospital for Sick Children, Göteborg University, University of Minnesota/TRIA Orthopaedic Center, Washington University School of Medicine | Osteochondritis Dissecans | 05/64 | 12/64 | | |
| Conant, Emily F |
NCT04854304: Abbreviate or FAST Breast MRI for Supplemental Breast Cancer Screening for Black Women at Average Risk and Dense Breasts |
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| Recruiting | N/A | 500 | US | Fast Breast Abbreviated Magnetic Renounce Imaging | Abramson Cancer Center at Penn Medicine | Breast Diseases | 07/25 | 07/26 | | |
| Mandell, David |
NCT04245423: The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions |
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| Active, not recruiting | N/A | 567 | US | Collaborative Care for Opioid Use Disorders and Mental Health Conditions, Augmented Usual Care, Collaborative Care for Opioid Use Disorders and Mental Health Conditions Plus Certified Recovery Specialists | University of Pennsylvania, Weill Medical College of Cornell University | Opioid-use Disorder, Mental Health Conditions | 03/25 | 02/26 | | |
| Active, not recruiting | N/A | 308 | US | Mind the Gap | Health Resources and Services Administration (HRSA), University of Rochester, University of Kansas, University of Pennsylvania, Drexel University, University of California, Davis, University of Washington | Autism Spectrum Disorder, Neurodevelopmental Disorders | 08/25 | 08/25 | | |
| Active, not recruiting | N/A | 264 | US | Remaking Recess (RR) | Health Resources and Services Administration (HRSA), University of California, Davis, University of Kansas, University of Washington, University of Pennsylvania, University of Rochester, Drexel University | Autism Spectrum Disorder, Neurodevelopmental Disorders | 08/25 | 12/25 | | |
| Weinstein, Susan |
| Active, not recruiting | N/A | 500 | US | | University of Pennsylvania | Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating | 09/24 | 09/24 | | |
| Wolk, David |
| Active, not recruiting | N/A | 327 | US | CPAP, continuous positive airway pressure therapy | University of Pennsylvania, National Institute on Aging (NIA) | Mild Cognitive Impairment, Sleep Apnea, Obstructive | 01/23 | 07/25 | | |
| Recruiting | N/A | 200 | US | the radiotracer 18F-AV-1451 | University of Pennsylvania, National Institutes of Health (NIH), National Institute on Aging (NIA) | Normal Controls, MCI | 05/26 | 05/26 | | |
| Recruiting | N/A | 850 | Europe, US, RoW | Flortaucipir, 18F-AV-1451 (also known as [F-18]T807 or LY3191748), Florbetaben, AV-45, Neuraceq, Fluorodeoxyglucose, FDG | Indiana University, Alzheimer's Therapeutic Research Institute, National Institute on Aging (NIA), Alzheimer's Association | Early Onset Alzheimer Disease, Alzheimer Disease, Mild Cognitive Impairment | 05/25 | 05/25 | | |
| Recruiting | N/A | 2000 | Canada, US | | University of Southern California, Northern California Institute of Research and Education, National Institute on Aging (NIA), Alzheimer's Therapeutic Research Institute | Mild Cognitive Impairment (MCI), Alzheimer's Disease (AD) | 12/24 | 12/24 | | |
NCT04251130: Linking Tau PET to Medial Temporal Lobe Subregions With High Resolution MRI |
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| Recruiting | N/A | 150 | US | 2-(2-([18F]fluoro)pyridin-4-yl)-9H-pyrrolo[2,3-b:4,5-c']dipyridine, [18F]PI-2620 | University of Pennsylvania, National Institutes of Health (NIH) | Mild Cognitive Impairment | 01/26 | 01/26 | | |
| Recruiting | N/A | 160 | US | [18F]AV-1451, [F-18]T807 | University of Pennsylvania, Pennsylvania Department of Health | Cognitive Decline, Alzheimer Disease | 05/27 | 05/27 | | |
MCP, NCT05658913: Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU) |
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| Recruiting | N/A | 100 | US | AV-1451, 7-(6-[18F]fluoropyridin-3-yl)-5H-pyrido[4,3-b]indole | University of Pennsylvania, Massachusetts General Hospital | Alzheimer's Disease | 12/27 | 12/29 | | |
| Burkhardt, Jan-Karl |
SPINNERS, NCT05458908: ProSPective Evaluation of Non-contrast sINe spiN Flat-dEtectoR CT for the Detection of Intracranial hemorrhageS |
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| Recruiting | N/A | 252 | Europe, US | Non-contrast cranial MDCT head scan, Non-contrast syngo DynaCT Sine Spin head scan and application software | University Hospital, Basel, Switzerland, Siemens Healthineers AG | Stroke | 04/25 | 07/25 | | |
| Active, not recruiting | N/A | 246 | US | Treatment of Intracranial Aneurysms | Medtronic Neurovascular Clinical Affairs | Intracranial Aneurysm | 03/26 | 04/28 | | |
| Recruiting | N/A | 1000 | US | MicroVention Mechanical Thrombectomy Devices as first-line treatment | Microvention-Terumo, Inc. | Acute Ischemic Stroke, Vessel Occlusion, Stroke, Ischemic | 12/25 | 12/25 | | |
WEB PAS, NCT04839705: Post Approval Study - Evaluate the Long-Term Safety and Effectiveness of the WEB Device |
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| Recruiting | N/A | 180 | US | WEB | Microvention-Terumo, Inc. | Wide Neck Bifurcation Intracranial Aneurysms | 12/25 | 12/29 | | |
| Recruiting | N/A | 150 | US | Citadel Embolization Device | Stryker Neurovascular | Unruptured Wide-neck Aneurysms | 06/26 | 06/26 | | |
NCT05409989: MicroVention, Inc. Flow Re-Direction Endoluminal Device X (FRED™ X™) Post-Approval Study |
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| Recruiting | N/A | 154 | US | FRED™ X™, Flow Re-Direction Endoluminal Device X | Microvention-Terumo, Inc. | Intracranial Aneurysm | 09/29 | 11/29 | | |
| Recruiting | N/A | 40000 | Europe, Canada, Japan, US, RoW | Stroke/Thrombectomy/Aneurysm-specific surgical procedures | Medical University of South Carolina | Stroke, Thromboses, Intracranial, Aneurysm, Brain | 01/55 | 01/55 | | |
| Gill, Saar |
NCT03766126: Lentivirally Redirected CD123 Autologous T Cells in AML |
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| Active, not recruiting | 1 | 22 | US | CART123 cells; cyclophosphamide; fludarabine, T Cells Containing Anti-CD123 Signaling Domains | University of Pennsylvania | Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia, Adult, Acute Myeloid Leukemia, Refractory | 12/33 | 12/33 | | |
ALLOHA, NCT05473910: A Study of TSC-100 and TSC-101 in AML, ALL and MDS Patients Undergoing Haploidentical Donor Transplantation |
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| Recruiting | 1 | 63 | US | SOC + TSC-100, SOC + TSC-101, Control | TScan Therapeutics, Inc. | AML, Myelodysplastic Syndromes, ALL, Adult | 12/25 | 06/26 | | |
| Not yet recruiting | 1 | 12 | NA | CART123 Cells, Ruxolitinib 10 MG Oral Tablet, Ruxolitinib 5 MG | University of Pennsylvania, Novartis | Relapsed AML, Refractory AML | 03/45 | 03/45 | | |
| Nazarian, Saman |
NCT04642976: Prospective Evaluation of CT Guided Ablation of Cardiac Ganglionated Plexi |
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| Completed | N/A | 30 | US | Ganglionated Plexi mapping and ablation using Natus Cortical Stimulator and standard ablation catheters, Vagal stimulation using Parasym tragal stimulator | University of Pennsylvania | Atrial Fibrillation | 01/24 | 01/24 | | |
STABLE-VT, NCT05828667: The STandard Versus ImAging SuBstrate Aided Ablation in Severe Left VEntricular Dysfunction VT. |
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| Suspended | N/A | 20 | US | Incorporation of CT and/or c-MRI derived myocardial scar with 3D electroanatomical mapping (EAM). | University of Pennsylvania | Cardiovascular Diseases | 03/25 | 03/26 | | |
| Nunez, Jessica |
| Recruiting | N/A | 60 | US | CT scans | University of Pennsylvania | Bicuspid | 12/25 | 12/25 | | |
AeCE, NCT05271578: MRI and Biological Markers of Acute E-Cigarette Exposure in Smokers and Vapers |
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| Recruiting | N/A | 40 | US | Standardized Electronic Research Cigarette, SREC, Nicotine Research Cigarette, NRC | University of Pennsylvania, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI) | Vascular Reactivity, Serum Biomarkers | 08/25 | 08/25 | | |
NCT04854304: Abbreviate or FAST Breast MRI for Supplemental Breast Cancer Screening for Black Women at Average Risk and Dense Breasts |
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| Recruiting | N/A | 500 | US | Fast Breast Abbreviated Magnetic Renounce Imaging | Abramson Cancer Center at Penn Medicine | Breast Diseases | 07/25 | 07/26 | | |
| Karabucak, Bekir |
NCT06110494: A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment |
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| Completed | 4 | 44 | US | Iron oxide nanoparticles treatment Ferumoxytol/H2O2, Fer, Feraheme, NaOCl, Sodium Hypochlorite, Active comparator, NaCl, Placebo comparator, saline, supplementary irrigation, NaOCl with passive ultrasonic activation, adjunctive irrigation step | University of Pennsylvania | Apical Periodontitis, Pulp Disease, Dental | 03/22 | 03/22 | | |
NCT06545084: Evaluation of Periapical Healing Following Endodontic Microsurgery With Leukocyte and Platelet Rich Fibrin (L-PRF) |
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| Recruiting | N/A | 50 | US | Leukocyte and Platelet Rich Fibrin | University of Pennsylvania | Apical Periodontitis | 06/25 | 06/26 | | |
NCT05959629: Erbium, Chromium: Yttrium, Scandium, Gallium, Garnet (Er,Cr:YSGG) Laser in Root Canal Disinfection |
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| Recruiting | N/A | 52 | US | Waterlase Express™, BIOLASE®, Er,Cr:YSGG laser, Waterlase Express™, Sodium Hypochlorite, NaOCl | University of Pennsylvania | Endodontic Disease, Root Canal Infection | 07/25 | 07/27 | | |
| Combs, Martha |
| Recruiting | N/A | 200 | US | the radiotracer 18F-AV-1451 | University of Pennsylvania, National Institutes of Health (NIH), National Institute on Aging (NIA) | Normal Controls, MCI | 05/26 | 05/26 | | |
NCT04251130: Linking Tau PET to Medial Temporal Lobe Subregions With High Resolution MRI |
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| Recruiting | N/A | 150 | US | 2-(2-([18F]fluoro)pyridin-4-yl)-9H-pyrrolo[2,3-b:4,5-c']dipyridine, [18F]PI-2620 | University of Pennsylvania, National Institutes of Health (NIH) | Mild Cognitive Impairment | 01/26 | 01/26 | | |
MCP, NCT05658913: Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU) |
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| Recruiting | N/A | 100 | US | AV-1451, 7-(6-[18F]fluoropyridin-3-yl)-5H-pyrido[4,3-b]indole | University of Pennsylvania, Massachusetts General Hospital | Alzheimer's Disease | 12/27 | 12/29 | | |
| Pellecchia, Melanie |
| Enrolling by invitation | N/A | 600 | US | PEACE Online Resources, PEACE Weekly Group Facilitation, PEACE Weekly Individual Facilitation | University of Pennsylvania, Institute of Education Sciences, Michigan State University | Autism Spectrum Disorder | 11/27 | 11/27 | | |
| Active, not recruiting | N/A | 308 | US | Mind the Gap | Health Resources and Services Administration (HRSA), University of Rochester, University of Kansas, University of Pennsylvania, Drexel University, University of California, Davis, University of Washington | Autism Spectrum Disorder, Neurodevelopmental Disorders | 08/25 | 08/25 | | |
| Boyd, Brian |
| Active, not recruiting | N/A | 308 | US | Mind the Gap | Health Resources and Services Administration (HRSA), University of Rochester, University of Kansas, University of Pennsylvania, Drexel University, University of California, Davis, University of Washington | Autism Spectrum Disorder, Neurodevelopmental Disorders | 08/25 | 08/25 | | |
| Active, not recruiting | N/A | 358 | US | Self-Determined Learning Model of Instruction (SDLMI) | Health Resources and Services Administration (HRSA), University of California, Davis, University of Kansas, University of Washington, University of Pennsylvania, University of Rochester, Drexel University | Autism Spectrum Disorder, Neurodevelopmental Disorders | 08/25 | 12/25 | | |
FITBI, NCT05125003: Family-Implemented Treatment on the Behavioral Inflexibility of Children With Autism |
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| Recruiting | N/A | 100 | US | FITBI, Parental Education | University of Kansas | Autism Spectrum Disorder, Repetitive Compulsive Behavior | 12/25 | 03/26 | | |
| Blanch, Erica |
| Active, not recruiting | N/A | 308 | US | Mind the Gap | Health Resources and Services Administration (HRSA), University of Rochester, University of Kansas, University of Pennsylvania, Drexel University, University of California, Davis, University of Washington | Autism Spectrum Disorder, Neurodevelopmental Disorders | 08/25 | 08/25 | | |
| Active, not recruiting | N/A | 264 | US | Remaking Recess (RR) | Health Resources and Services Administration (HRSA), University of California, Davis, University of Kansas, University of Washington, University of Pennsylvania, University of Rochester, Drexel University | Autism Spectrum Disorder, Neurodevelopmental Disorders | 08/25 | 12/25 | | |
| Bajaj, Archna |
NCT06292013: A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a) |
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| Recruiting | 3 | 12500 | Europe, Canada, Japan, US, RoW | Lepodisiran Sodium, LY3819469, Placebo | Eli Lilly and Company | Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a) | 03/29 | 03/29 | | |
| Recruiting | 3 | 1328 | Europe, Canada, US, RoW | Plozasiran Injection, ARO-APOC3, Placebo | Arrowhead Pharmaceuticals | Hypertriglyceridemia | 07/26 | 10/26 | | |
| Recruiting | 3 | 300 | Europe, Canada, US, RoW | Plozasiran Injection, ARO-APOC3, Placebo | Arrowhead Pharmaceuticals | Severe Hypertriglyceridemia | 07/26 | 10/26 | | |
| Recruiting | 2 | 30 | US | obicetrapib 10 mg + obicetrapib/evolocumab 140 mg Q 2 weeks, Repatha | NewAmsterdam Pharma | Dyslipidemias | 10/25 | 12/25 | | |
NCT05646381: A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis |
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| Recruiting | 2 | 502 | Europe, Canada, US, RoW | Pelacarsen (TQJ230) 80mg, TQJ230, Matching placebo, Placebo | Novartis Pharmaceuticals | Aortic Stenosis | 01/29 | 01/29 | | |
NCT05972278: Investigating the Effect of Obicetrapib on Lipoprotein Metabolism |
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| Active, not recruiting | 1 | 22 | US | Obicetrapib, tablets | NewAmsterdam Pharma, University of Pennsylvania | Lipid Metabolism | 09/24 | 10/24 | | |
| Lane, Jackie |
| Recruiting | N/A | 200 | US | the radiotracer 18F-AV-1451 | University of Pennsylvania, National Institutes of Health (NIH), National Institute on Aging (NIA) | Normal Controls, MCI | 05/26 | 05/26 | | |
NCT04251130: Linking Tau PET to Medial Temporal Lobe Subregions With High Resolution MRI |
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| Recruiting | N/A | 150 | US | 2-(2-([18F]fluoro)pyridin-4-yl)-9H-pyrrolo[2,3-b:4,5-c']dipyridine, [18F]PI-2620 | University of Pennsylvania, National Institutes of Health (NIH) | Mild Cognitive Impairment | 01/26 | 01/26 | | |
MCP, NCT05658913: Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU) |
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| Recruiting | N/A | 100 | US | AV-1451, 7-(6-[18F]fluoropyridin-3-yl)-5H-pyrido[4,3-b]indole | University of Pennsylvania, Massachusetts General Hospital | Alzheimer's Disease | 12/27 | 12/29 | | |
| Morgan, Jennifer |
NCT05804825: Testing the Persuasiveness of Pro-inoculation Arguments |
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| Completed | N/A | 523 | US | Argument inoculation messages, Simple forewarning message | University of Pennsylvania | Vaccination Hesitancy, Human Papillomavirus Vaccination, Vaccine Refusal | 05/23 | 05/23 | | |
| Active, not recruiting | N/A | 60 | US | Axonics System | Axonics, Inc. | Overactive Bladder Syndrome, Urinary Urge Incontinence, Sacral Neuromodulation | 10/23 | 12/24 | | |
NCT06186765: F15 Recharge Free Axonics SNM System Clinical Study |
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| Recruiting | N/A | 130 | Europe, US | Axonics SNM System (Model 4101) | Axonics, Inc. | Urinary Urge Incontinence (UUI), Urinary Frequency (UF), Fecal Incontinence (FI) | 03/25 | 06/26 | | |
