Walther, Thomas |
| Recruiting | 3 | 3200 | Europe, Canada, US | Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy | Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center | Atrial Fibrillation, Stroke, Bleeding | 08/26 | 08/26 | | |
SURTAVI, NCT01586910: Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (). |
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| Active, not recruiting | N/A | 1746 | Europe, Canada, US | Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI), Surgical Aortic Valve Replacement (SAVR), Medtronic CoreValve® Evolut R System Transcatheter Aortic Valve Implantation (TAVI) | Medtronic Cardiovascular | Severe Aortic Stenosis | 07/18 | 11/26 | | |
| Terminated | N/A | 26 | Europe | HARPOON Beating Heart Mitral Valve Repair System (MVRS) | Edwards Lifesciences, ICON plc | Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse | 11/22 | 11/22 | | |
NCT02387112: Early Versus Emergency Left Ventricular Assist Device Implantation in Patients Awaiting Cardiac Transplantation |
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| Active, not recruiting | N/A | 102 | Europe | Early VAD implantation | German Heart Institute, Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Helmholtz Zentrum München, University Medicine Greifswald, University of Göttingen | End Stage Heart Disease | 03/24 | 12/24 | | |
| Recruiting | N/A | 800 | Europe, Canada, US, RoW | | Universitätsklinikum Hamburg-Eppendorf, Montreal Heart Institute, University Hospital, Bordeaux | Mitral Regurgitation | 03/25 | 12/30 | | |
PROVE, NCT05539573: ACURATE neo2™ - Post Market Safety and Performance Surveillance in Aortic Stenosis |
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| Active, not recruiting | N/A | 1043 | Europe | Planned TAVI with the ACURATE neo2™ aortic bioprosthesis and ACURATE neo2™ transfemoral delivery system. | University of Leipzig, National University of Ireland, Galway | Aortic Stenosis | 04/25 | 04/25 | | |
| Active, not recruiting | N/A | 200 | Europe, RoW | Tendyne™ Mitral Valve System, Transcatheter Mitral Valve Implantation (TMVI) | Abbott Medical Devices | Mitral Valve Regurgitation | 05/25 | 05/29 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MitraClip™ device implantation, Mitral Valve Repair Surgery | Abbott Medical Devices | Mitral Valve Regurgitation | 04/26 | 04/34 | | |
PRIMARY, NCT05051033: Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds |
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| Recruiting | N/A | 450 | Europe, Canada, US | Mitral valve repair, Mitral valve surgery, Transcatheter edge-to-edge repair, TEER | Annetine Gelijns, National Heart, Lung, and Blood Institute (NHLBI) | Mitral Valve Regurgitation | 11/28 | 11/30 | | |
| Recruiting | N/A | 400 | Europe | Tendyne Mitral Valve System | Klinikum der Universitaet Muenchen | Mitral Regurgitation | 12/26 | 12/27 | | |
Rothe, Jürgen |
PROVE, NCT05539573: ACURATE neo2™ - Post Market Safety and Performance Surveillance in Aortic Stenosis |
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| Active, not recruiting | N/A | 1043 | Europe | Planned TAVI with the ACURATE neo2™ aortic bioprosthesis and ACURATE neo2™ transfemoral delivery system. | University of Leipzig, National University of Ireland, Galway | Aortic Stenosis | 04/25 | 04/25 | | |