Vanderbilt Medical Center
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 80 Trials 
156 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Newhouse, Paul A
NCT05231798: Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

Active, not recruiting
2
20
US
[18F]-FEOBV Radiotracer, [18F]-fluoroethoxybenzovesamicol
Vanderbilt University Medical Center, Vanderbilt Kennedy Center
Down Syndrome, Down Syndrome, Partial Trisomy 21, Alzheimer Disease
04/25
04/25
MIND, NCT02720445: Memory Improvement Through Nicotine Dosing () Study

Active, not recruiting
2
380
US
Nicotine Transdermal Patch, Placebo Patch
University of Southern California, National Institute on Aging (NIA), Vanderbilt University, Alzheimer's Therapeutic Research Institute
Mild Cognitive Impairment
09/25
09/25
2-HOBA, NCT06432166: 2-Hydroxybenzylamine () Study in Early Alzheimer's Patients

Not yet recruiting
1/2
48
US
2-hydroxybenzylamine acetate, 2-HOBA, Placebo
MTI Biotech Inc, Vanderbilt University Medical Center
Alzheimer Disease, Mild Cognitive Impairment
06/27
12/27
CHAMP, NCT04129060: Cholinergic Health After Menopause

Recruiting
1
120
US
Cholinergic antagonist
University of Vermont, Vanderbilt University Medical Center
Postmenopausal Symptoms, Aging, Alzheimer Disease
11/24
01/25
NCT04756232: Cholinergic Mechanisms of Attention in Aging

Recruiting
1
80
US
Mecamylamine Challenge, Placebo Comparator Challenge
Vanderbilt University Medical Center
Subjective Cognitive Decline
05/25
05/25
AMoCC-SCD, NCT06002477: Attentional Mechanisms in SCD

Not yet recruiting
1
80
US
Mecamylamine Challenge, Placebo Comparator Challenge
Vanderbilt University Medical Center
Subjective Cognitive Decline
06/28
06/28
NCT05283629: nCCR for Chemotherapy Related Cognitive Impairment Randomized Study

Recruiting
N/A
20
US
Neuroplasticity-based Computerized Cognitive Remediation, Education Control Condition
Vanderbilt University Medical Center, University of Utah
Chemo-brain, Chemotherapy-Related Cognitive Impairment
06/24
03/25
ADNI3, NCT02854033: Alzheimer's Disease Neuroimaging Initiative 3

Recruiting
N/A
2000
Canada, US
University of Southern California, Northern California Institute of Research and Education, National Institute on Aging (NIA), Alzheimer's Therapeutic Research Institute
Mild Cognitive Impairment (MCI), Alzheimer's Disease (AD)
12/24
12/24
TRC-DS, NCT04165109: Trial-Ready Cohort-Down Syndrome

Recruiting
N/A
450
Europe, US
Flutafuranol, [18F]NAV4694, NAV4694, Pittsburgh Compound (PIB), [11C]-PIB, PIB, MK6240, [18F]MK-6240
University of Southern California, National Institute on Aging (NIA), Alzheimer's Clinical Trials Consortium, Alzheimer's Therapeutic Research Institute
Down Syndrome, Alzheimer Disease, Dementia
12/25
12/25
ADNI4, NCT05617014: Alzheimer's Disease Neuroimaging Initiative 4

Recruiting
N/A
1500
Canada, US
Neuraceq, Florbetaben, Amyvid, Florbetapir, Tauvid, Flortaucipir, 18F-AV-1451, AV-1451, MK-6240, florquinitau F-18, [18F]MK-6240, NAV4694, [18F]NAV4694, [18F]AZD4694, PI-2620, [18F]PI-2620
University of Southern California, Northern California Institute of Research and Education, National Institute on Aging (NIA), Alzheimer's Therapeutic Research Institute
Mild Cognitive Impairment, Alzheimer Disease, Dementia
07/27
07/27
Vaezi, Michael F
NCT05550194: VZV in the Enteric Nervous System: Pathogenesis and Consequences

Recruiting
4
40
US
ValACYclovir 1000 MG, Valtrex, Shingrix, Zoster vaccine recombinant
Vanderbilt University Medical Center, Columbia University
Achalasia
08/26
08/26
NCT03063463: Mechanisms of Weight Loss in Patients Diagnosed With Achalasia

Enrolling by invitation
N/A
50
US
pneumatic dilation, surgical myotomy
Vanderbilt University Medical Center
Achalasia
06/25
06/25
NCT03103789: Assessment of Esophageal Epithelium Integrity With Use of a Novel Mucosal Impedance Device

Enrolling by invitation
N/A
75
US
single catheter mucosal impedance testing, balloon assembly mucosal impedance testing
Vanderbilt University Medical Center, Sandhill Scientific
Gastro Esophageal Reflux
08/25
08/25
Lee, Donald H
NCT00521846: ExploR™ Modular Radial Head Data Collection

Active, not recruiting
N/A
50
US
Biomet Explor Modular Radial Head Replacement
Vanderbilt University Medical Center
Elbow Fracture
08/25
08/25
BJAM, NCT01376024: Study on Basal Joint Arthritis Prospective

Recruiting
N/A
500
US
Columbia University, Orthopedic Research and Education Foundation
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
08/25
08/25
Johnson, Julia V
stAAAble, NCT06001918: Nectero EAST System Clinical Study

Suspended
2/3
400
US, RoW
Nectero EAST System
Nectero Medical, Inc.
Abdominal Aortic Aneurysm
03/27
12/29
INI-PD, NCT04251585: Intranasal Insulin in Parkinson's Disease

Completed
2
31
US
Regular Novolin R, Placebo
HealthPartners Institute
Parkinson Disease
08/24
08/24
TRIUMPH, NCT06554717: Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

Not yet recruiting
2
100
US
Tesamorelin, Egrifta, TH9507, growth hormone-releasing hormone analogue, Placebo, Exercise
Massachusetts General Hospital, University of Colorado - Anschutz Medical Campus
HIV-1-infection, Frailty, Impaired Physical Function, Abdominal Obesity, Aging
03/28
09/28
ACTIVATE, NCT05819359: Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD

Active, not recruiting
2
237
Europe, Canada, US
BIA 28-6156 10 mg, BIA 28-6156 60 mg, Placebo
Bial R&D Investments, S.A.
Parkinson's Disease
03/26
07/26
Obremskey, William T
NCT06201676: Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients

Recruiting
4
458
US
Ketorolac Injection, Toradol, Normal Saline, Sodium Chloride
Massachusetts General Hospital, United States Department of Defense
Orthopaedic Polytrauma, Chronic Opioid Use
12/26
08/27
NCT04678154: Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

Recruiting
3
1200
US
Standard of care, Vancomycin and Tobramycin
Major Extremity Trauma Research Consortium, United States Department of Defense
Post Operative Surgical Site Infection
09/24
03/25
NCT04964947: Tobramycin Injection to Prevent Infection in Open Fractures

Recruiting
3
600
US
Tobramycin Injection
Massachusetts General Hospital, United States Department of Defense
Wound Infection, Fractures, Open, Surgical Site Infection
09/25
09/25
POvIV2, NCT05699174: PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

Recruiting
3
250
US
Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics
Major Extremity Trauma Research Consortium, United States Department of Defense
Infections, Infected Wound, Nonunion of Fracture, Injury Leg, Amputation, Internal Fixation; Complications, Infection or Inflammation, Fracture, Lower Extremity Fracture, Antibiotic Side Effect
09/25
09/26
NCT05766670: Intramedullary Calcium Sulfate Antibiotic Depot

Recruiting
3
497
US
Vancomycin Hydrochloride, antibacterial prescription medicine, Gentamicin, injection is used to treat certain serious infections that are caused by bacteria such as meningitis, Standard Intramedullary Nail, metal rod that is inserted into the medullary cavity of a bone and across the fracture in order to provide a solid support for the fractured bone
Wake Forest University Health Sciences
Open tíbia Fracture, Osteomyelitis Tibia, Tibial Fractures
01/27
01/28
NCT04671173: Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome

Recruiting
N/A
50
US
Measurement of the Intra-Compartmental Pressure with the MY01 device
McGill University Health Centre/Research Institute of the McGill University Health Centre, United States Department of Defense, Hennepin Healthcare Research Institute, Vanderbilt University Medical Center
Acute Compartment Syndrome
02/23
03/23
MBTK, NCT04047030: The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma

Recruiting
N/A
450
US
None- Observational Study
Major Extremity Trauma Research Consortium
Gait
12/23
08/24
NCT04028414: Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures

Active, not recruiting
N/A
450
US
Early Weight Bearing
Major Extremity Trauma Research Consortium
Rehabilitation
10/24
03/25
NCT06249126: Primary Subtalar Arthrodesis for Calcaneal Fractures

Recruiting
N/A
218
US
Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA), Open Reduction Internal Fixation (ORIF) only
Wake Forest University Health Sciences
Calcaneus Fracture
12/26
12/26
PPFx, NCT03378557: Periprosthetic Fracture Registry

Recruiting
N/A
600
Europe, US, RoW
AO Innovation Translation Center
Periprosthetic Fractures, Periprosthetic Fracture Around Prosthetic Joint Implant
01/27
03/27
NCT06877793: Real-Time Diagnosis of Life-Threatening Necrotizing Soft Tissue Infections (NSTI) Using Indocyanine Green (ICG) Kinetic Modeling

Not yet recruiting
N/A
420
US
Administration of indocyanine green (ICG) and fluorescence imaging
Eric R. Henderson, National Institute of Allergy and Infectious Diseases (NIAID)
Necrotizing Fascitis
06/30
07/30
FROST, NCT03598530: Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures

Active, not recruiting
N/A
1000
Europe, US, RoW
Surgery, Operative, Surgical treatment
AO Clinical Investigation and Publishing Documentation, DePuy Synthes
Tibial Fracture, Fracture of the Tibia Type AO/OTA 42
03/25
12/25
Kuhn, John E
MOONSI, NCT02075775: MOON Shoulder Instability-Cohort of Patients Undergoing Operative Treatment.

Recruiting
N/A
2500
US
Carolyn M Hettrich, University of Michigan, University of California, San Francisco, University of Kentucky, Hospital for Special Surgery, New York, University of Colorado, Denver, Ohio State University, Washington University School of Medicine, Orthopedic Institute, Sioux Falls, SD, Vanderbilt University, Brigham and Women's Hospital
Other Instability, Shoulder, Dislocations, Subluxations, Recurrent Dislocation of Shoulder Region
12/22
12/42
MOON, NCT00762580: Features to Predict Success With Nonoperative Treatment of Patients With Rotator Cuff Tears

Completed
N/A
452
US
Vanderbilt University, University of Colorado, Denver, Ohio State University, University of Iowa, University of California, San Francisco, Arthrex, Inc., Knoxville Orthopedic Clinic, Washington University School of Medicine, Sports Medicine and Shoulder Surgery Orthopedic Institute, Hospital for Special Surgery, New York
Rotator Cuff Tear
01/24
01/24
Piana, Robert N
NCT05069558: Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion

Active, not recruiting
N/A
450
Europe, Canada, US
Investigational PFO Closure Device, Standard of Care PFO Closure Device
Occlutech International AB
Stroke, Patent Foramen Ovale, PFO
11/25
10/26
REDUCE PAS, NCT03821129: GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

Recruiting
N/A
636
US
PFO closure with GORE® CARDIOFORM Septal Occluder
W.L.Gore & Associates
Stroke, PFO - Patent Foramen Ovale
10/28
10/31
Phibbs, Fenna T
ACTIVATE, NCT05819359: Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD

Active, not recruiting
2
237
Europe, Canada, US
BIA 28-6156 10 mg, BIA 28-6156 60 mg, Placebo
Bial R&D Investments, S.A.
Parkinson's Disease
03/26
07/26
NCT01734122: Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

Recruiting
N/A
60
US
Questionnaires / Observational Assessments
Vanderbilt University Medical Center
Tremor, Essential Tremor, Parkinson Disease, Radiosurgery, Quality of Life
02/27
02/28
Drake, Wonder P
RISE-UP, NCT05567133: Risk Indicators of Sarcoidosis Evolution-Unified Protocol

Recruiting
N/A
200
US
University of California, San Francisco, Vanderbilt University Medical Center, University of Texas, Southwestern Medical Center at Dallas, Wayne State University
Sarcoidosis, Pulmonary
03/26
03/26
O'Neill, Kevin R
NCT04712214: Use of Non-invasive Optical Analysis in Neurosurgery

Recruiting
N/A
50
Europe
Intra-operative multispectral / hyperspectral analysis
Imperial College London
Brain Tumour, Glioma, Meningioma, Brain Metastases, Schwannoma
10/23
10/23
Dai, Qi
NCT02965703: Aspirin in Preventing Colorectal Cancer in Patients With Colorectal Adenoma

Active, not recruiting
2
81
US
Aspirin, Acetylsalicylic Acid, ASA, Aspergum, Ecotrin, Empirin, Entericin, Extren, Measurin, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Placebo Administration, Questionnaire Administration, Rectal Biopsy, Biopsy of Rectum
National Cancer Institute (NCI)
Colorectal Adenoma, Colorectal Carcinoma
01/23
12/25
NCT01105169: Precision-Based Magnesium Trial

Active, not recruiting
N/A
265
US
Magnesium glycinate, Placebo
Vanderbilt University Medical Center
Colorectal Cancer
07/25
07/25
Yu, Chang
NCT05862337: Anlotinib Hydrochloride Capsules Combined With Penpulimab Injection for the Treatment of Hepatocellular Carcinoma at High Risk of Recurrence.

Recruiting
3
480
RoW
Anlotinib hydrochloride capsules, Penpulimab injection, Anlotinib hydrochloride capsules -matching placebo, Penpulimab injection -matching placebo
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Hepatocellular Carcinoma
08/24
12/26
NCT06310590: Safety and Efficacy of TareSphere in Patients with Unresectable Hepatocellular Carcinoma

Active, not recruiting
1
40
RoW
NRT6003 Injection, Yttrium-90 carbon microspheres
Chengdu New Radiomedicine Technology Co. LTD.
Unresectable Hepatocellular Carcinoma
10/25
12/25
NCT06331923: Assessing the Effectiveness of Continuous Glucose Monitoring in Enhancing Surgical Outcomes for Patients with Diabetes

Recruiting
N/A
10168
RoW
Continuous glucose monitoring (CGM) device
Beijing Tsinghua Chang Gung Hospital, Peking University International Hospital, Wang Jing Hospital, ZhuHai Hospital, Beijing Hospital, Siyang County Hospital of Traditional Chinese Medicine, Second Hospital of Shanxi Medical University, Henan Provincial Chest Hospital, Fuzhou First Hospital, Pinggu Hospital of Beijing Traditional Chinese Medicine Hospital, The First Affiliated Hospital of Anhui University of Chinese Medicine, The First Affiliated Hospital of Zhengzhou University, Mindong Hospital of Ningde, The Fifth Hospital of Xiamen, People's Hospital of Ningxia Hui Autonomous Region, The First People's Hospital of Changzhou, The Fifth hospital of Deyang, Suzhou Municipal Hospital, Tang-Du Hospital, Yiyang Central Hospital, First Affiliated Hospital of Xinjiang Medical University, Peng Ding Shan Shi Zhong Yi Yi Yuan, Yueyang Central Hospital, The First People's Hospital of Lianyungang, Haimen District Traditional Chinese Medicine Hospital, The 910th Hospital, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Beijing Tiantan Hospital, Affiliated Hospital of Jiangsu University, Liaocheng People's Hospital, Beijing Chao Yang Hospital, Jilin City Hospital of Chemical Industry, Creen Hospital-465, Wuhan Central Hospital, Air Force Military Medical University, China, Shanghai Tong Ren Hospital, Beijing Anzhen Hospital, Emergency General Hospital, Beijing Tongren Hospital, Civil Aviation General Hospital, Peking University Shougang Hospital, The First Affiliated Hospital of Anhui Medical University, Chinese PLA Central Hospital
Comprehensive Complication Index
10/25
12/25
NCT01105169: Precision-Based Magnesium Trial

Active, not recruiting
N/A
265
US
Magnesium glycinate, Placebo
Vanderbilt University Medical Center
Colorectal Cancer
07/25
07/25
TMCP, NCT06434766: Multicenter iTBS Neuromodulation for PTSD Treatment

Recruiting
N/A
140
RoW
sham stimulation, intermittent theta-burst stimulation (iTBS)
Second Affiliated Hospital, School of Medicine, Zhejiang University, Shanghai Mental Health Center, The Affiliated Kangning Hospital of Ningbo University, The First Affiliated Hospital of Anhui Medical University
Posttraumatic Stress Disorder
12/25
05/26
Shrubsole, Martha J
NCT04229992: Calcium: Magnesium Balance, Microbiota, and Necroptosis and Inflammation

Completed
N/A
250
US
Magnesium glycinate, Placebo
Vanderbilt University Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Cancer Institute (NCI)
Colorectal Cancer
02/24
03/24
NCT01105169: Precision-Based Magnesium Trial

Active, not recruiting
N/A
265
US
Magnesium glycinate, Placebo
Vanderbilt University Medical Center
Colorectal Cancer
07/25
07/25
Kimmelstiel, Carey
DTU-STEMI, NCT03947619: Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: the STEMI-DTU Trial

Active, not recruiting
N/A
527
Europe, Canada, US
Impella CP® placement prior to reperfusion with Primary PCI
Abiomed Inc.
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
09/24
10/30
CATALYST, NCT04226547: Amplatzer Amulet LAAO Vs. NOAC

Recruiting
N/A
2650
Europe, Canada, Japan, US, RoW
Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC
Abbott Medical Devices
Atrial Fibrillation, Stroke, Bleeding
08/27
08/30
NCT05069558: Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion

Active, not recruiting
N/A
450
Europe, Canada, US
Investigational PFO Closure Device, Standard of Care PFO Closure Device
Occlutech International AB
Stroke, Patent Foramen Ovale, PFO
11/25
10/26
Oto, Aytekin
NCT03585660: Developing an Imaging-Based Tool to Identify Areas for Prostate Cancer Biopsy

Completed
N/A
106
US
Diagnostic MRI, Diagnostic Prostate Biopsy, Risk Map DSS tool
University of Chicago
Prostate Cancer
06/23
11/23
NCT05710380: MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy

Recruiting
N/A
180
US
Risk Map Decision Support System (DSS)., Magnetic Resonance Imaging (MRI), Magnetic Resonance Imaging (MRI) Guided Biopsy
University of Chicago
Prostate Cancer, Prostate Adenocarcinoma, Prostate Neoplasm
05/26
05/26
LeWitt, Peter
NCT06312800: Acamprosate and Methazolamide for Essential Tremor

Withdrawn
2
US
Acamprosate, Placebo, Methazolamide
Henry Ford Health System
Essential Tremor
06/17
12/17
NCT05979415: Study to Evaluate the Efficacy and Safety of Staccato Apomorphine (AZ-009) in Patients With Parkinson's Disease Experiencing OFF Episodes

Terminated
2
8
US
Apomorphine Cartridge, placebo
Alexza Pharmaceuticals, Inc., Peachtree BioResearch Solutions, DSG, ISS, Inc.
Parkinson Disease
02/24
02/24
NCT03655236: PROSEEK: A Phase 2 Study In Early Parkinson's Disease Patients Evaluating The Safety And Efficacy Of Abl Tyrosine Kinase Inhibition Using K0706

Terminated
2
513
Europe, US, RoW
K0706, placebo
Sun Pharma Advanced Research Company Limited
Early Parkinson Disease
04/24
06/24
ACTIVATE, NCT05819359: Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD

Active, not recruiting
2
237
Europe, Canada, US
BIA 28-6156 10 mg, BIA 28-6156 60 mg, Placebo
Bial R&D Investments, S.A.
Parkinson's Disease
03/26
07/26
NCT05958030: GyroGlove Use in Essential Tremor Patients

Not yet recruiting
N/A
30
Europe, US
Placebo, GyroGlove
GyroGear Ltd
Essential Tremor
10/25
12/25
NCT06219629: Parkinson's Disease Progression Study

Active, not recruiting
N/A
82
US
Koneksa Health, Merck Sharp & Dohme LLC, Regeneron Pharmaceuticals
Parkinson Disease
02/26
02/26
Konda, Sanjit
NCT04678154: Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

Recruiting
3
1200
US
Standard of care, Vancomycin and Tobramycin
Major Extremity Trauma Research Consortium, United States Department of Defense
Post Operative Surgical Site Infection
09/24
03/25
POvIV2, NCT05699174: PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

Recruiting
3
250
US
Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics
Major Extremity Trauma Research Consortium, United States Department of Defense
Infections, Infected Wound, Nonunion of Fracture, Injury Leg, Amputation, Internal Fixation; Complications, Infection or Inflammation, Fracture, Lower Extremity Fracture, Antibiotic Side Effect
09/25
09/26
MAGIK, NCT05627479: for Femoral/Tibial Shaft Fractures

Withdrawn
2
50
US
GIK solution, Isotonic Normal Saline Solution
NYU Langone Health
Femoral Shaft Fracture, Tibial Shaft Fracture
01/26
01/27
NCT05118087: Comparison of Bracing With Co-aptation Splinting for the Initial Treatment of Acute Humeral Shaft Fractures: The COBRAS Trials

Recruiting
N/A
66
US
Webril Padded Plaster Splint, Pre-Fabricated Fracture Brace
NYU Langone Health
Humeral Fractures
12/24
07/25
FROST, NCT03598530: Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures

Active, not recruiting
N/A
1000
Europe, US, RoW
Surgery, Operative, Surgical treatment
AO Clinical Investigation and Publishing Documentation, DePuy Synthes
Tibial Fracture, Fracture of the Tibia Type AO/OTA 42
03/25
12/25
Chakravarthy, Bapsi
NCT03958721: Capecitabine and Radiotherapy in the Adjuvant Treatment of Resistant Breast Cancer

Completed
1
20
US
Capecitabine, Radiotherapy
A Bapsi Chakravarthy, MD
Resistant Breast Cancer, Non-metastatic Invasive Breast Cancer
10/23
10/23
Yang, Joanna
SWIFT RT, NCT06559540: Ultra-Hypofractionated vs. Hypofractionated Radiation for Node-Positive Breast Cancer

Recruiting
2
220
US
Hypofractionated radiation, RT, Ultra-hypofractionated breast/chest wall and regional nodal radiation, SWIFT RT
Washington University School of Medicine
Node-positive Breast Cancer
04/34
04/34
NCT06623630: Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function

Recruiting
1
12
US
Cyclophosphamide, Ciltacabtagene Autoleucel, Carvykti, cilta-cel, Total body irradiation, TBI
Washington University School of Medicine, American Cancer Society, Inc., Cures Within Reach
Multiple Myeloma
04/26
03/27
EARN, NCT06582849: Enhanced Assistance During Radiotherapy for Unmet Essential Needs

Recruiting
N/A
33
US
Standard assistance, Enhanced assistance
Washington University School of Medicine, American Society of Clinical Oncology
Bone Cancer, Brain Cancer, Colorectal Cancer, Esophagus Cancer, Lymphoma, Salivary Gland Cancer, Head and Neck Cancer, Liver Cancer, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer, Small Intestine Cancer, Stomach Cancer, Urinary Bladder Cancer, Anal Cancer, Blood Cancer, Breast Cancer, Cervical Cancer, Lung Cancer, Kidney Cancer, Penile Cancer, Skin Cancer, Testicular Cancer, Thyroid Cancer, Uterine Cancer, Vaginal Cancer, Vulvar Cancer
12/25
12/25
NCT03681535: Dose-Reduced Consolidation Radiation Therapy in Patients With Diffuse Large B-cell Lymphoma

Active, not recruiting
N/A
241
Europe, Japan, US, RoW
Radiation Therapy
Duke University
Diffuse Large B Cell Lymphoma
08/25
08/28
NCT05069558: Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion

Active, not recruiting
N/A
450
Europe, Canada, US
Investigational PFO Closure Device, Standard of Care PFO Closure Device
Occlutech International AB
Stroke, Patent Foramen Ovale, PFO
11/25
10/26
BreaStBRT, NCT04849871: Single Fraction Accelerated Partial Breast Irradiation vs. Five Fraction Accelerated Partial Breast Irradiation for Low-risk Stage 0 and I Breast Carcinoma

Active, not recruiting
N/A
134
US
External Beam Accelerated Partial Breast Irradiation, APBI
Washington University School of Medicine, The Foundation for Barnes-Jewish Hospital
Breast Carcinoma, Breast Cancer, Stage 0 Breast Cancer, Stage I Breast Cancer
07/29
07/29
Maldonado, Fabien
FROSTBITE-3, NCT06105801: EBUS-TBNA vs Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing

Recruiting
3
250
US
Endobronchial ultrasound with transbronchial needle aspiration, Bronchoscopy, Cryobiopsy
Vanderbilt-Ingram Cancer Center
Lung Cancer
10/27
10/28
LuTK02, NCT04495153: CAN-2409 Plus Prodrug With Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLC

Active, not recruiting
2
90
US
Aglatimagene besadenovec, CAN-2409, AdV-tk
Candel Therapeutics, Inc., NYU Langone Health
Non Small Cell Lung Cancer
12/24
12/26
NEWTON, NCT03831386: Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System

Recruiting
N/A
200
Europe, US
Vacuum-Based IPC, Gravity-Based IPC
Johns Hopkins University, Rocket Medical plc, Swedish Medical Center, Medical University of South Carolina, University of Oxford, Vanderbilt University Medical Center, Northwest Community Healthcare
Pleural Effusion
12/26
12/26
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis

Active, not recruiting
N/A
270
Europe, US
RheOx Bronchial Rheoplasty, Sham Procedure
Gala Therapeutics, Inc.
Chronic Bronchitis
05/24
10/25
VERITAS, NCT04250194: Navigation Endoscopy to Reach Indeterminate Lung Nodules Versus Trans-Thoracic Needle Aspiration

Active, not recruiting
N/A
256
US
CT-Guided Biopsy, Navigation bronchoscopy
Vanderbilt-Ingram Cancer Center, Medtronic
Lung Nodule
06/24
07/25
NCT06593106: Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

Recruiting
N/A
30
US
Cryosurgery, Robotic Bronchoscopy, Bronchoscopy with Biopsy, Resection, Chest Radiography, Computed Tomography, Biospecimen Collection, Electronic Health Record Review
Vanderbilt-Ingram Cancer Center, National Cancer Institute (NCI), Swim Across America
Stage I Lung Cancer, Stage II Lung Cancer
12/25
08/26
NCT06638398: Biomarker Platform (Virtual Nodule Clinic) for the Management of Indeterminate Pulmonary Nodules

Recruiting
N/A
400
US
Computed Tomography, Diagnostic Procedure, Best Practice, Electronic Health Record Review
Vanderbilt-Ingram Cancer Center, National Cancer Institute (NCI)
Lung Neoplasm
12/26
12/27
NCT04996173: Cryospray Therapy Versus Standard of Care for Benign Airway Stenosis (CryoStasis)

Recruiting
N/A
40
US
Spray cryotherapy, Ballon Dilation, Radial Incision
Vanderbilt University Medical Center, Virginia Commonwealth University, University of Mississippi Medical Center
Pulmonary Disease
12/25
04/26
NCT00898313: Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer

Recruiting
N/A
4000
US
comparative genomic hybridization, gene expression microarray analysis, proteomic profiling analysis, biologic sample preservation procedure, nasal brushing, Blood draw, Urine collection, sputum sample, fluorescence bronchoscopy with airway biopsy, fine needle aspiration of the lung, thoracentesis
Vanderbilt-Ingram Cancer Center, National Cancer Institute (NCI)
Lung Cancer
01/25
01/25
RELIANT, NCT05705544: Robotic Versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT: (the Trial)

Completed
N/A
445
US
ILLUMISITE™ Platform (EMN bronchoscopy), Ion™ Endoluminal System (SSCB bronchoscopy)
Vanderbilt University Medical Center
Peripheral Pulmonary Lesions
04/24
04/24
Lenihan, Daniel J
NCT01311843: Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment (PREDICT)

Active, not recruiting
N/A
830
US
Questionnaire, Survey, MDASI, M. D. Anderson Symptom Index - Heart Failure, MDASI-HF
M.D. Anderson Cancer Center, Alere San Diego
Breast Cancer, Gastrointestinal Cancer, Genitourinary Cancer, Leukemia, Lung Cancer
01/26
 
Robbins, Ivan M
IMPAHCT-FUL, NCT05557942 / 2021-006864-25: Inhaled Imatinib Pulmonary Arterial Hypertension Clinical Trial - Follow Up Long Term Extension

Terminated
3
186
Europe, Canada, US, RoW
AV-101
Aerovate Therapeutics, Aerovate Therapeutics Inc
Pulmonary Arterial Hypertension
08/24
08/24
IMPAHCT, NCT05036135 / 2021-001910-13: A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH)

Terminated
2/3
202
Europe, Canada, US, RoW
AV-101, Placebo
Aerovate Therapeutics, Aerovate Therapeutics, Inc.
Pulmonary Arterial Hypertension
08/24
08/24
ELEVATE 2, NCT04712669 / 2020-004971-42: A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension

Completed
2
108
Europe, Canada, US, RoW
rodatristat ethyl 300 mg tablet BID, rodatristat ethyl 600 mg BID, Placebo
Altavant Sciences GmbH
Pulmonary Arterial Hypertension
06/23
08/23
NCT04908397: Carnitine Consumption and Augmentation in Pulmonary Arterial Hypertension

Completed
1
10
US
L-carnitine, Carnitine, Carnitor
Vanderbilt University Medical Center
Pulmonary Arterial Hypertension, Familial Primary Pulmonary Hypertension, Primary Pulmonary Hypertension, Lung Diseases, Carnitine Nutritional Deficiency
06/23
06/23
NCT04469842: Early Use of Long-acting Tacrolimus in Lung Transplant Recipients

Recruiting
1
48
US
Tacrolimus Extended Release Oral Tablet [Envarsus], Envarsus XR, Tacrolimus, Intermediate Release Tacrolimus, Prograf, FK506, Mycophenolate Mofetil Hydrochloride, MMF, CellCept, Prednisone, Deltasone, Azathioprine, Imuran
Vanderbilt University Medical Center, Veloxis Pharmaceuticals
Lung Transplant; Complications
06/26
12/26
Shah, Ashish
REVERSE-IT, NCT04286438 / 2019-004457-92: Bentracimab in Ticagrelor-treated Patients With Uncontrolled Bleeding or Requiring Urgent Surgery or Invasive Procedure

Completed
3
226
Europe, Canada, US, RoW
Bentracimab (PB2452) Infusion
SFJ Pharmaceuticals, Inc.
Hemorrhage, Urgent Surgery, Invasive Procedure
09/24
09/24
NCT06264388: DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

Recruiting
2
33
US
DB107-RRV, DB107-FC, Ancobon, Ancotil
Ashish Shah, Denovo Biopharma LLC, National Cancer Institute (NCI)
High Grade Glioma, Anaplastic Astrocytoma
05/34
05/34
NCT03765619: Postoperative Aspirin and Ankle Fracture Healing

Completed
1
500
US
Aspirin
University of Alabama at Birmingham
Ankle Fractures
11/19
11/19
STARLITE, NCT06428045: for Unresectable High-Grade Gliomas

Not yet recruiting
1
24
US
Magnetic Resonance (MR)-guided Laser Interstitial Thermal Therapy (LITT), MR-Guided LITT, Abacavir, Lamivudine, Ritonavir, Norvir, RTV, Temozolomide, TMZ, Focal Radiotherapy
University of Miami, Medtronic
High Grade Glioma
07/29
07/30
NCT03522753: Staple Versus Suture Closure for Foot and Ankle Surgery

Withdrawn
N/A
340
NA
Metal skin staples, metal clips, skin clips, staples, Nylon sutures, sutures
University of Alabama at Birmingham
Incision, Foot Ankle Injuries
10/22
09/23
NCT03857945: Effect of Preoperative Mobility Device Training on Postoperative Fall Incidence

Recruiting
N/A
250
US
Preoperative mobility device(s) training
University of Alabama at Birmingham
Injury; Muscle, Ankle, and Foot, Multiple
03/26
05/26
HF-HOPE, NCT04581252: Heart Failure HemOdynamic Prognostic Evaluation and OutcomE () Study

Not yet recruiting
N/A
500
Canada
Non-invasive cardiac system
University of Manitoba
Heart Failure
11/23
04/24
MR-ICP, NCT03212976: Clinical Efficacy of a Non-Invasive Measure of Intracranial Pressure

Terminated
N/A
11
US
Phase contrast magnetic resonance imaging
University of Miami
Intracranial Pathology, Intracranial Hypertension
10/20
10/20
NCT03780452: Compression Nail for Tibiocalcaneal Arthrodesis

Completed
N/A
30
US
novel dynamic compression intramedullary nail
University of Alabama at Birmingham, MedShape, Inc
Subtalar Arthritis, Ankle Arthritis
07/24
07/24
NCT05047068: OCS Heart Perfusion Post-Approval Registry

Active, not recruiting
N/A
350
US
OCS Heart System
TransMedics
Transplant
12/25
12/29
NCT05881278: XVIVO Heart Perfusion System (XHPS) With Supplemented XVIVO Heart Solution (SXHS)

Active, not recruiting
N/A
141
US
Non-Ischemic Heart Preservation (NIHP) using the XVIVO Heart Preservation System (XHPS)
XVIVO Perfusion
Heart Failure, Transplant; Failure, Heart
11/25
11/29
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
N/A
1056
Europe, Canada, US
Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Medtronic Cardiovascular
Mitral Valve Regurgitation
10/26
09/36
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Newhouse, Paul A
NCT05231798: Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

Active, not recruiting
2
20
US
[18F]-FEOBV Radiotracer, [18F]-fluoroethoxybenzovesamicol
Vanderbilt University Medical Center, Vanderbilt Kennedy Center
Down Syndrome, Down Syndrome, Partial Trisomy 21, Alzheimer Disease
04/25
04/25
MIND, NCT02720445: Memory Improvement Through Nicotine Dosing () Study

Active, not recruiting
2
380
US
Nicotine Transdermal Patch, Placebo Patch
University of Southern California, National Institute on Aging (NIA), Vanderbilt University, Alzheimer's Therapeutic Research Institute
Mild Cognitive Impairment
09/25
09/25
2-HOBA, NCT06432166: 2-Hydroxybenzylamine () Study in Early Alzheimer's Patients

Not yet recruiting
1/2
48
US
2-hydroxybenzylamine acetate, 2-HOBA, Placebo
MTI Biotech Inc, Vanderbilt University Medical Center
Alzheimer Disease, Mild Cognitive Impairment
06/27
12/27
CHAMP, NCT04129060: Cholinergic Health After Menopause

Recruiting
1
120
US
Cholinergic antagonist
University of Vermont, Vanderbilt University Medical Center
Postmenopausal Symptoms, Aging, Alzheimer Disease
11/24
01/25
NCT04756232: Cholinergic Mechanisms of Attention in Aging

Recruiting
1
80
US
Mecamylamine Challenge, Placebo Comparator Challenge
Vanderbilt University Medical Center
Subjective Cognitive Decline
05/25
05/25
AMoCC-SCD, NCT06002477: Attentional Mechanisms in SCD

Not yet recruiting
1
80
US
Mecamylamine Challenge, Placebo Comparator Challenge
Vanderbilt University Medical Center
Subjective Cognitive Decline
06/28
06/28
NCT05283629: nCCR for Chemotherapy Related Cognitive Impairment Randomized Study

Recruiting
N/A
20
US
Neuroplasticity-based Computerized Cognitive Remediation, Education Control Condition
Vanderbilt University Medical Center, University of Utah
Chemo-brain, Chemotherapy-Related Cognitive Impairment
06/24
03/25
ADNI3, NCT02854033: Alzheimer's Disease Neuroimaging Initiative 3

Recruiting
N/A
2000
Canada, US
University of Southern California, Northern California Institute of Research and Education, National Institute on Aging (NIA), Alzheimer's Therapeutic Research Institute
Mild Cognitive Impairment (MCI), Alzheimer's Disease (AD)
12/24
12/24
TRC-DS, NCT04165109: Trial-Ready Cohort-Down Syndrome

Recruiting
N/A
450
Europe, US
Flutafuranol, [18F]NAV4694, NAV4694, Pittsburgh Compound (PIB), [11C]-PIB, PIB, MK6240, [18F]MK-6240
University of Southern California, National Institute on Aging (NIA), Alzheimer's Clinical Trials Consortium, Alzheimer's Therapeutic Research Institute
Down Syndrome, Alzheimer Disease, Dementia
12/25
12/25
ADNI4, NCT05617014: Alzheimer's Disease Neuroimaging Initiative 4

Recruiting
N/A
1500
Canada, US
Neuraceq, Florbetaben, Amyvid, Florbetapir, Tauvid, Flortaucipir, 18F-AV-1451, AV-1451, MK-6240, florquinitau F-18, [18F]MK-6240, NAV4694, [18F]NAV4694, [18F]AZD4694, PI-2620, [18F]PI-2620
University of Southern California, Northern California Institute of Research and Education, National Institute on Aging (NIA), Alzheimer's Therapeutic Research Institute
Mild Cognitive Impairment, Alzheimer Disease, Dementia
07/27
07/27
Vaezi, Michael F
NCT05550194: VZV in the Enteric Nervous System: Pathogenesis and Consequences

Recruiting
4
40
US
ValACYclovir 1000 MG, Valtrex, Shingrix, Zoster vaccine recombinant
Vanderbilt University Medical Center, Columbia University
Achalasia
08/26
08/26
NCT03063463: Mechanisms of Weight Loss in Patients Diagnosed With Achalasia

Enrolling by invitation
N/A
50
US
pneumatic dilation, surgical myotomy
Vanderbilt University Medical Center
Achalasia
06/25
06/25
NCT03103789: Assessment of Esophageal Epithelium Integrity With Use of a Novel Mucosal Impedance Device

Enrolling by invitation
N/A
75
US
single catheter mucosal impedance testing, balloon assembly mucosal impedance testing
Vanderbilt University Medical Center, Sandhill Scientific
Gastro Esophageal Reflux
08/25
08/25
Lee, Donald H
NCT00521846: ExploR™ Modular Radial Head Data Collection

Active, not recruiting
N/A
50
US
Biomet Explor Modular Radial Head Replacement
Vanderbilt University Medical Center
Elbow Fracture
08/25
08/25
BJAM, NCT01376024: Study on Basal Joint Arthritis Prospective

Recruiting
N/A
500
US
Columbia University, Orthopedic Research and Education Foundation
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
08/25
08/25
Johnson, Julia V
stAAAble, NCT06001918: Nectero EAST System Clinical Study

Suspended
2/3
400
US, RoW
Nectero EAST System
Nectero Medical, Inc.
Abdominal Aortic Aneurysm
03/27
12/29
INI-PD, NCT04251585: Intranasal Insulin in Parkinson's Disease

Completed
2
31
US
Regular Novolin R, Placebo
HealthPartners Institute
Parkinson Disease
08/24
08/24
TRIUMPH, NCT06554717: Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

Not yet recruiting
2
100
US
Tesamorelin, Egrifta, TH9507, growth hormone-releasing hormone analogue, Placebo, Exercise
Massachusetts General Hospital, University of Colorado - Anschutz Medical Campus
HIV-1-infection, Frailty, Impaired Physical Function, Abdominal Obesity, Aging
03/28
09/28
ACTIVATE, NCT05819359: Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD

Active, not recruiting
2
237
Europe, Canada, US
BIA 28-6156 10 mg, BIA 28-6156 60 mg, Placebo
Bial R&D Investments, S.A.
Parkinson's Disease
03/26
07/26
Obremskey, William T
NCT06201676: Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients

Recruiting
4
458
US
Ketorolac Injection, Toradol, Normal Saline, Sodium Chloride
Massachusetts General Hospital, United States Department of Defense
Orthopaedic Polytrauma, Chronic Opioid Use
12/26
08/27
NCT04678154: Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

Recruiting
3
1200
US
Standard of care, Vancomycin and Tobramycin
Major Extremity Trauma Research Consortium, United States Department of Defense
Post Operative Surgical Site Infection
09/24
03/25
NCT04964947: Tobramycin Injection to Prevent Infection in Open Fractures

Recruiting
3
600
US
Tobramycin Injection
Massachusetts General Hospital, United States Department of Defense
Wound Infection, Fractures, Open, Surgical Site Infection
09/25
09/25
POvIV2, NCT05699174: PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

Recruiting
3
250
US
Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics
Major Extremity Trauma Research Consortium, United States Department of Defense
Infections, Infected Wound, Nonunion of Fracture, Injury Leg, Amputation, Internal Fixation; Complications, Infection or Inflammation, Fracture, Lower Extremity Fracture, Antibiotic Side Effect
09/25
09/26
NCT05766670: Intramedullary Calcium Sulfate Antibiotic Depot

Recruiting
3
497
US
Vancomycin Hydrochloride, antibacterial prescription medicine, Gentamicin, injection is used to treat certain serious infections that are caused by bacteria such as meningitis, Standard Intramedullary Nail, metal rod that is inserted into the medullary cavity of a bone and across the fracture in order to provide a solid support for the fractured bone
Wake Forest University Health Sciences
Open tíbia Fracture, Osteomyelitis Tibia, Tibial Fractures
01/27
01/28
NCT04671173: Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome

Recruiting
N/A
50
US
Measurement of the Intra-Compartmental Pressure with the MY01 device
McGill University Health Centre/Research Institute of the McGill University Health Centre, United States Department of Defense, Hennepin Healthcare Research Institute, Vanderbilt University Medical Center
Acute Compartment Syndrome
02/23
03/23
MBTK, NCT04047030: The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma

Recruiting
N/A
450
US
None- Observational Study
Major Extremity Trauma Research Consortium
Gait
12/23
08/24
NCT04028414: Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures

Active, not recruiting
N/A
450
US
Early Weight Bearing
Major Extremity Trauma Research Consortium
Rehabilitation
10/24
03/25
NCT06249126: Primary Subtalar Arthrodesis for Calcaneal Fractures

Recruiting
N/A
218
US
Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA), Open Reduction Internal Fixation (ORIF) only
Wake Forest University Health Sciences
Calcaneus Fracture
12/26
12/26
PPFx, NCT03378557: Periprosthetic Fracture Registry

Recruiting
N/A
600
Europe, US, RoW
AO Innovation Translation Center
Periprosthetic Fractures, Periprosthetic Fracture Around Prosthetic Joint Implant
01/27
03/27
NCT06877793: Real-Time Diagnosis of Life-Threatening Necrotizing Soft Tissue Infections (NSTI) Using Indocyanine Green (ICG) Kinetic Modeling

Not yet recruiting
N/A
420
US
Administration of indocyanine green (ICG) and fluorescence imaging
Eric R. Henderson, National Institute of Allergy and Infectious Diseases (NIAID)
Necrotizing Fascitis
06/30
07/30
FROST, NCT03598530: Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures

Active, not recruiting
N/A
1000
Europe, US, RoW
Surgery, Operative, Surgical treatment
AO Clinical Investigation and Publishing Documentation, DePuy Synthes
Tibial Fracture, Fracture of the Tibia Type AO/OTA 42
03/25
12/25
Kuhn, John E
MOONSI, NCT02075775: MOON Shoulder Instability-Cohort of Patients Undergoing Operative Treatment.

Recruiting
N/A
2500
US
Carolyn M Hettrich, University of Michigan, University of California, San Francisco, University of Kentucky, Hospital for Special Surgery, New York, University of Colorado, Denver, Ohio State University, Washington University School of Medicine, Orthopedic Institute, Sioux Falls, SD, Vanderbilt University, Brigham and Women's Hospital
Other Instability, Shoulder, Dislocations, Subluxations, Recurrent Dislocation of Shoulder Region
12/22
12/42
MOON, NCT00762580: Features to Predict Success With Nonoperative Treatment of Patients With Rotator Cuff Tears

Completed
N/A
452
US
Vanderbilt University, University of Colorado, Denver, Ohio State University, University of Iowa, University of California, San Francisco, Arthrex, Inc., Knoxville Orthopedic Clinic, Washington University School of Medicine, Sports Medicine and Shoulder Surgery Orthopedic Institute, Hospital for Special Surgery, New York
Rotator Cuff Tear
01/24
01/24
Piana, Robert N
NCT05069558: Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion

Active, not recruiting
N/A
450
Europe, Canada, US
Investigational PFO Closure Device, Standard of Care PFO Closure Device
Occlutech International AB
Stroke, Patent Foramen Ovale, PFO
11/25
10/26
REDUCE PAS, NCT03821129: GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

Recruiting
N/A
636
US
PFO closure with GORE® CARDIOFORM Septal Occluder
W.L.Gore & Associates
Stroke, PFO - Patent Foramen Ovale
10/28
10/31
Phibbs, Fenna T
ACTIVATE, NCT05819359: Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD

Active, not recruiting
2
237
Europe, Canada, US
BIA 28-6156 10 mg, BIA 28-6156 60 mg, Placebo
Bial R&D Investments, S.A.
Parkinson's Disease
03/26
07/26
NCT01734122: Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

Recruiting
N/A
60
US
Questionnaires / Observational Assessments
Vanderbilt University Medical Center
Tremor, Essential Tremor, Parkinson Disease, Radiosurgery, Quality of Life
02/27
02/28
Drake, Wonder P
RISE-UP, NCT05567133: Risk Indicators of Sarcoidosis Evolution-Unified Protocol

Recruiting
N/A
200
US
University of California, San Francisco, Vanderbilt University Medical Center, University of Texas, Southwestern Medical Center at Dallas, Wayne State University
Sarcoidosis, Pulmonary
03/26
03/26
O'Neill, Kevin R
NCT04712214: Use of Non-invasive Optical Analysis in Neurosurgery

Recruiting
N/A
50
Europe
Intra-operative multispectral / hyperspectral analysis
Imperial College London
Brain Tumour, Glioma, Meningioma, Brain Metastases, Schwannoma
10/23
10/23
Dai, Qi
NCT02965703: Aspirin in Preventing Colorectal Cancer in Patients With Colorectal Adenoma

Active, not recruiting
2
81
US
Aspirin, Acetylsalicylic Acid, ASA, Aspergum, Ecotrin, Empirin, Entericin, Extren, Measurin, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Placebo Administration, Questionnaire Administration, Rectal Biopsy, Biopsy of Rectum
National Cancer Institute (NCI)
Colorectal Adenoma, Colorectal Carcinoma
01/23
12/25
NCT01105169: Precision-Based Magnesium Trial

Active, not recruiting
N/A
265
US
Magnesium glycinate, Placebo
Vanderbilt University Medical Center
Colorectal Cancer
07/25
07/25
Yu, Chang
NCT05862337: Anlotinib Hydrochloride Capsules Combined With Penpulimab Injection for the Treatment of Hepatocellular Carcinoma at High Risk of Recurrence.

Recruiting
3
480
RoW
Anlotinib hydrochloride capsules, Penpulimab injection, Anlotinib hydrochloride capsules -matching placebo, Penpulimab injection -matching placebo
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Hepatocellular Carcinoma
08/24
12/26
NCT06310590: Safety and Efficacy of TareSphere in Patients with Unresectable Hepatocellular Carcinoma

Active, not recruiting
1
40
RoW
NRT6003 Injection, Yttrium-90 carbon microspheres
Chengdu New Radiomedicine Technology Co. LTD.
Unresectable Hepatocellular Carcinoma
10/25
12/25
NCT06331923: Assessing the Effectiveness of Continuous Glucose Monitoring in Enhancing Surgical Outcomes for Patients with Diabetes

Recruiting
N/A
10168
RoW
Continuous glucose monitoring (CGM) device
Beijing Tsinghua Chang Gung Hospital, Peking University International Hospital, Wang Jing Hospital, ZhuHai Hospital, Beijing Hospital, Siyang County Hospital of Traditional Chinese Medicine, Second Hospital of Shanxi Medical University, Henan Provincial Chest Hospital, Fuzhou First Hospital, Pinggu Hospital of Beijing Traditional Chinese Medicine Hospital, The First Affiliated Hospital of Anhui University of Chinese Medicine, The First Affiliated Hospital of Zhengzhou University, Mindong Hospital of Ningde, The Fifth Hospital of Xiamen, People's Hospital of Ningxia Hui Autonomous Region, The First People's Hospital of Changzhou, The Fifth hospital of Deyang, Suzhou Municipal Hospital, Tang-Du Hospital, Yiyang Central Hospital, First Affiliated Hospital of Xinjiang Medical University, Peng Ding Shan Shi Zhong Yi Yi Yuan, Yueyang Central Hospital, The First People's Hospital of Lianyungang, Haimen District Traditional Chinese Medicine Hospital, The 910th Hospital, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Beijing Tiantan Hospital, Affiliated Hospital of Jiangsu University, Liaocheng People's Hospital, Beijing Chao Yang Hospital, Jilin City Hospital of Chemical Industry, Creen Hospital-465, Wuhan Central Hospital, Air Force Military Medical University, China, Shanghai Tong Ren Hospital, Beijing Anzhen Hospital, Emergency General Hospital, Beijing Tongren Hospital, Civil Aviation General Hospital, Peking University Shougang Hospital, The First Affiliated Hospital of Anhui Medical University, Chinese PLA Central Hospital
Comprehensive Complication Index
10/25
12/25
NCT01105169: Precision-Based Magnesium Trial

Active, not recruiting
N/A
265
US
Magnesium glycinate, Placebo
Vanderbilt University Medical Center
Colorectal Cancer
07/25
07/25
TMCP, NCT06434766: Multicenter iTBS Neuromodulation for PTSD Treatment

Recruiting
N/A
140
RoW
sham stimulation, intermittent theta-burst stimulation (iTBS)
Second Affiliated Hospital, School of Medicine, Zhejiang University, Shanghai Mental Health Center, The Affiliated Kangning Hospital of Ningbo University, The First Affiliated Hospital of Anhui Medical University
Posttraumatic Stress Disorder
12/25
05/26
Shrubsole, Martha J
NCT04229992: Calcium: Magnesium Balance, Microbiota, and Necroptosis and Inflammation

Completed
N/A
250
US
Magnesium glycinate, Placebo
Vanderbilt University Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Cancer Institute (NCI)
Colorectal Cancer
02/24
03/24
NCT01105169: Precision-Based Magnesium Trial

Active, not recruiting
N/A
265
US
Magnesium glycinate, Placebo
Vanderbilt University Medical Center
Colorectal Cancer
07/25
07/25
Kimmelstiel, Carey
DTU-STEMI, NCT03947619: Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: the STEMI-DTU Trial

Active, not recruiting
N/A
527
Europe, Canada, US
Impella CP® placement prior to reperfusion with Primary PCI
Abiomed Inc.
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
09/24
10/30
CATALYST, NCT04226547: Amplatzer Amulet LAAO Vs. NOAC

Recruiting
N/A
2650
Europe, Canada, Japan, US, RoW
Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC
Abbott Medical Devices
Atrial Fibrillation, Stroke, Bleeding
08/27
08/30
NCT05069558: Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion

Active, not recruiting
N/A
450
Europe, Canada, US
Investigational PFO Closure Device, Standard of Care PFO Closure Device
Occlutech International AB
Stroke, Patent Foramen Ovale, PFO
11/25
10/26
Oto, Aytekin
NCT03585660: Developing an Imaging-Based Tool to Identify Areas for Prostate Cancer Biopsy

Completed
N/A
106
US
Diagnostic MRI, Diagnostic Prostate Biopsy, Risk Map DSS tool
University of Chicago
Prostate Cancer
06/23
11/23
NCT05710380: MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy

Recruiting
N/A
180
US
Risk Map Decision Support System (DSS)., Magnetic Resonance Imaging (MRI), Magnetic Resonance Imaging (MRI) Guided Biopsy
University of Chicago
Prostate Cancer, Prostate Adenocarcinoma, Prostate Neoplasm
05/26
05/26
LeWitt, Peter
NCT06312800: Acamprosate and Methazolamide for Essential Tremor

Withdrawn
2
US
Acamprosate, Placebo, Methazolamide
Henry Ford Health System
Essential Tremor
06/17
12/17
NCT05979415: Study to Evaluate the Efficacy and Safety of Staccato Apomorphine (AZ-009) in Patients With Parkinson's Disease Experiencing OFF Episodes

Terminated
2
8
US
Apomorphine Cartridge, placebo
Alexza Pharmaceuticals, Inc., Peachtree BioResearch Solutions, DSG, ISS, Inc.
Parkinson Disease
02/24
02/24
NCT03655236: PROSEEK: A Phase 2 Study In Early Parkinson's Disease Patients Evaluating The Safety And Efficacy Of Abl Tyrosine Kinase Inhibition Using K0706

Terminated
2
513
Europe, US, RoW
K0706, placebo
Sun Pharma Advanced Research Company Limited
Early Parkinson Disease
04/24
06/24
ACTIVATE, NCT05819359: Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD

Active, not recruiting
2
237
Europe, Canada, US
BIA 28-6156 10 mg, BIA 28-6156 60 mg, Placebo
Bial R&D Investments, S.A.
Parkinson's Disease
03/26
07/26
NCT05958030: GyroGlove Use in Essential Tremor Patients

Not yet recruiting
N/A
30
Europe, US
Placebo, GyroGlove
GyroGear Ltd
Essential Tremor
10/25
12/25
NCT06219629: Parkinson's Disease Progression Study

Active, not recruiting
N/A
82
US
Koneksa Health, Merck Sharp & Dohme LLC, Regeneron Pharmaceuticals
Parkinson Disease
02/26
02/26
Konda, Sanjit
NCT04678154: Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

Recruiting
3
1200
US
Standard of care, Vancomycin and Tobramycin
Major Extremity Trauma Research Consortium, United States Department of Defense
Post Operative Surgical Site Infection
09/24
03/25
POvIV2, NCT05699174: PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

Recruiting
3
250
US
Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics
Major Extremity Trauma Research Consortium, United States Department of Defense
Infections, Infected Wound, Nonunion of Fracture, Injury Leg, Amputation, Internal Fixation; Complications, Infection or Inflammation, Fracture, Lower Extremity Fracture, Antibiotic Side Effect
09/25
09/26
MAGIK, NCT05627479: for Femoral/Tibial Shaft Fractures

Withdrawn
2
50
US
GIK solution, Isotonic Normal Saline Solution
NYU Langone Health
Femoral Shaft Fracture, Tibial Shaft Fracture
01/26
01/27
NCT05118087: Comparison of Bracing With Co-aptation Splinting for the Initial Treatment of Acute Humeral Shaft Fractures: The COBRAS Trials

Recruiting
N/A
66
US
Webril Padded Plaster Splint, Pre-Fabricated Fracture Brace
NYU Langone Health
Humeral Fractures
12/24
07/25
FROST, NCT03598530: Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures

Active, not recruiting
N/A
1000
Europe, US, RoW
Surgery, Operative, Surgical treatment
AO Clinical Investigation and Publishing Documentation, DePuy Synthes
Tibial Fracture, Fracture of the Tibia Type AO/OTA 42
03/25
12/25
Chakravarthy, Bapsi
NCT03958721: Capecitabine and Radiotherapy in the Adjuvant Treatment of Resistant Breast Cancer

Completed
1
20
US
Capecitabine, Radiotherapy
A Bapsi Chakravarthy, MD
Resistant Breast Cancer, Non-metastatic Invasive Breast Cancer
10/23
10/23
Yang, Joanna
SWIFT RT, NCT06559540: Ultra-Hypofractionated vs. Hypofractionated Radiation for Node-Positive Breast Cancer

Recruiting
2
220
US
Hypofractionated radiation, RT, Ultra-hypofractionated breast/chest wall and regional nodal radiation, SWIFT RT
Washington University School of Medicine
Node-positive Breast Cancer
04/34
04/34
NCT06623630: Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function

Recruiting
1
12
US
Cyclophosphamide, Ciltacabtagene Autoleucel, Carvykti, cilta-cel, Total body irradiation, TBI
Washington University School of Medicine, American Cancer Society, Inc., Cures Within Reach
Multiple Myeloma
04/26
03/27
EARN, NCT06582849: Enhanced Assistance During Radiotherapy for Unmet Essential Needs

Recruiting
N/A
33
US
Standard assistance, Enhanced assistance
Washington University School of Medicine, American Society of Clinical Oncology
Bone Cancer, Brain Cancer, Colorectal Cancer, Esophagus Cancer, Lymphoma, Salivary Gland Cancer, Head and Neck Cancer, Liver Cancer, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer, Small Intestine Cancer, Stomach Cancer, Urinary Bladder Cancer, Anal Cancer, Blood Cancer, Breast Cancer, Cervical Cancer, Lung Cancer, Kidney Cancer, Penile Cancer, Skin Cancer, Testicular Cancer, Thyroid Cancer, Uterine Cancer, Vaginal Cancer, Vulvar Cancer
12/25
12/25
NCT03681535: Dose-Reduced Consolidation Radiation Therapy in Patients With Diffuse Large B-cell Lymphoma

Active, not recruiting
N/A
241
Europe, Japan, US, RoW
Radiation Therapy
Duke University
Diffuse Large B Cell Lymphoma
08/25
08/28
NCT05069558: Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion

Active, not recruiting
N/A
450
Europe, Canada, US
Investigational PFO Closure Device, Standard of Care PFO Closure Device
Occlutech International AB
Stroke, Patent Foramen Ovale, PFO
11/25
10/26
BreaStBRT, NCT04849871: Single Fraction Accelerated Partial Breast Irradiation vs. Five Fraction Accelerated Partial Breast Irradiation for Low-risk Stage 0 and I Breast Carcinoma

Active, not recruiting
N/A
134
US
External Beam Accelerated Partial Breast Irradiation, APBI
Washington University School of Medicine, The Foundation for Barnes-Jewish Hospital
Breast Carcinoma, Breast Cancer, Stage 0 Breast Cancer, Stage I Breast Cancer
07/29
07/29
Maldonado, Fabien
FROSTBITE-3, NCT06105801: EBUS-TBNA vs Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing

Recruiting
3
250
US
Endobronchial ultrasound with transbronchial needle aspiration, Bronchoscopy, Cryobiopsy
Vanderbilt-Ingram Cancer Center
Lung Cancer
10/27
10/28
LuTK02, NCT04495153: CAN-2409 Plus Prodrug With Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLC

Active, not recruiting
2
90
US
Aglatimagene besadenovec, CAN-2409, AdV-tk
Candel Therapeutics, Inc., NYU Langone Health
Non Small Cell Lung Cancer
12/24
12/26
NEWTON, NCT03831386: Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System

Recruiting
N/A
200
Europe, US
Vacuum-Based IPC, Gravity-Based IPC
Johns Hopkins University, Rocket Medical plc, Swedish Medical Center, Medical University of South Carolina, University of Oxford, Vanderbilt University Medical Center, Northwest Community Healthcare
Pleural Effusion
12/26
12/26
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis

Active, not recruiting
N/A
270
Europe, US
RheOx Bronchial Rheoplasty, Sham Procedure
Gala Therapeutics, Inc.
Chronic Bronchitis
05/24
10/25
VERITAS, NCT04250194: Navigation Endoscopy to Reach Indeterminate Lung Nodules Versus Trans-Thoracic Needle Aspiration

Active, not recruiting
N/A
256
US
CT-Guided Biopsy, Navigation bronchoscopy
Vanderbilt-Ingram Cancer Center, Medtronic
Lung Nodule
06/24
07/25
NCT06593106: Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

Recruiting
N/A
30
US
Cryosurgery, Robotic Bronchoscopy, Bronchoscopy with Biopsy, Resection, Chest Radiography, Computed Tomography, Biospecimen Collection, Electronic Health Record Review
Vanderbilt-Ingram Cancer Center, National Cancer Institute (NCI), Swim Across America
Stage I Lung Cancer, Stage II Lung Cancer
12/25
08/26
NCT06638398: Biomarker Platform (Virtual Nodule Clinic) for the Management of Indeterminate Pulmonary Nodules

Recruiting
N/A
400
US
Computed Tomography, Diagnostic Procedure, Best Practice, Electronic Health Record Review
Vanderbilt-Ingram Cancer Center, National Cancer Institute (NCI)
Lung Neoplasm
12/26
12/27
NCT04996173: Cryospray Therapy Versus Standard of Care for Benign Airway Stenosis (CryoStasis)

Recruiting
N/A
40
US
Spray cryotherapy, Ballon Dilation, Radial Incision
Vanderbilt University Medical Center, Virginia Commonwealth University, University of Mississippi Medical Center
Pulmonary Disease
12/25
04/26
NCT00898313: Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer

Recruiting
N/A
4000
US
comparative genomic hybridization, gene expression microarray analysis, proteomic profiling analysis, biologic sample preservation procedure, nasal brushing, Blood draw, Urine collection, sputum sample, fluorescence bronchoscopy with airway biopsy, fine needle aspiration of the lung, thoracentesis
Vanderbilt-Ingram Cancer Center, National Cancer Institute (NCI)
Lung Cancer
01/25
01/25
RELIANT, NCT05705544: Robotic Versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT: (the Trial)

Completed
N/A
445
US
ILLUMISITE™ Platform (EMN bronchoscopy), Ion™ Endoluminal System (SSCB bronchoscopy)
Vanderbilt University Medical Center
Peripheral Pulmonary Lesions
04/24
04/24
Lenihan, Daniel J
NCT01311843: Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment (PREDICT)

Active, not recruiting
N/A
830
US
Questionnaire, Survey, MDASI, M. D. Anderson Symptom Index - Heart Failure, MDASI-HF
M.D. Anderson Cancer Center, Alere San Diego
Breast Cancer, Gastrointestinal Cancer, Genitourinary Cancer, Leukemia, Lung Cancer
01/26
 
Robbins, Ivan M
IMPAHCT-FUL, NCT05557942 / 2021-006864-25: Inhaled Imatinib Pulmonary Arterial Hypertension Clinical Trial - Follow Up Long Term Extension

Terminated
3
186
Europe, Canada, US, RoW
AV-101
Aerovate Therapeutics, Aerovate Therapeutics Inc
Pulmonary Arterial Hypertension
08/24
08/24
IMPAHCT, NCT05036135 / 2021-001910-13: A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH)

Terminated
2/3
202
Europe, Canada, US, RoW
AV-101, Placebo
Aerovate Therapeutics, Aerovate Therapeutics, Inc.
Pulmonary Arterial Hypertension
08/24
08/24
ELEVATE 2, NCT04712669 / 2020-004971-42: A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension

Completed
2
108
Europe, Canada, US, RoW
rodatristat ethyl 300 mg tablet BID, rodatristat ethyl 600 mg BID, Placebo
Altavant Sciences GmbH
Pulmonary Arterial Hypertension
06/23
08/23
NCT04908397: Carnitine Consumption and Augmentation in Pulmonary Arterial Hypertension

Completed
1
10
US
L-carnitine, Carnitine, Carnitor
Vanderbilt University Medical Center
Pulmonary Arterial Hypertension, Familial Primary Pulmonary Hypertension, Primary Pulmonary Hypertension, Lung Diseases, Carnitine Nutritional Deficiency
06/23
06/23
NCT04469842: Early Use of Long-acting Tacrolimus in Lung Transplant Recipients

Recruiting
1
48
US
Tacrolimus Extended Release Oral Tablet [Envarsus], Envarsus XR, Tacrolimus, Intermediate Release Tacrolimus, Prograf, FK506, Mycophenolate Mofetil Hydrochloride, MMF, CellCept, Prednisone, Deltasone, Azathioprine, Imuran
Vanderbilt University Medical Center, Veloxis Pharmaceuticals
Lung Transplant; Complications
06/26
12/26
Shah, Ashish
REVERSE-IT, NCT04286438 / 2019-004457-92: Bentracimab in Ticagrelor-treated Patients With Uncontrolled Bleeding or Requiring Urgent Surgery or Invasive Procedure

Completed
3
226
Europe, Canada, US, RoW
Bentracimab (PB2452) Infusion
SFJ Pharmaceuticals, Inc.
Hemorrhage, Urgent Surgery, Invasive Procedure
09/24
09/24
NCT06264388: DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

Recruiting
2
33
US
DB107-RRV, DB107-FC, Ancobon, Ancotil
Ashish Shah, Denovo Biopharma LLC, National Cancer Institute (NCI)
High Grade Glioma, Anaplastic Astrocytoma
05/34
05/34
NCT03765619: Postoperative Aspirin and Ankle Fracture Healing

Completed
1
500
US
Aspirin
University of Alabama at Birmingham
Ankle Fractures
11/19
11/19
STARLITE, NCT06428045: for Unresectable High-Grade Gliomas

Not yet recruiting
1
24
US
Magnetic Resonance (MR)-guided Laser Interstitial Thermal Therapy (LITT), MR-Guided LITT, Abacavir, Lamivudine, Ritonavir, Norvir, RTV, Temozolomide, TMZ, Focal Radiotherapy
University of Miami, Medtronic
High Grade Glioma
07/29
07/30
NCT03522753: Staple Versus Suture Closure for Foot and Ankle Surgery

Withdrawn
N/A
340
NA
Metal skin staples, metal clips, skin clips, staples, Nylon sutures, sutures
University of Alabama at Birmingham
Incision, Foot Ankle Injuries
10/22
09/23
NCT03857945: Effect of Preoperative Mobility Device Training on Postoperative Fall Incidence

Recruiting
N/A
250
US
Preoperative mobility device(s) training
University of Alabama at Birmingham
Injury; Muscle, Ankle, and Foot, Multiple
03/26
05/26
HF-HOPE, NCT04581252: Heart Failure HemOdynamic Prognostic Evaluation and OutcomE () Study

Not yet recruiting
N/A
500
Canada
Non-invasive cardiac system
University of Manitoba
Heart Failure
11/23
04/24
MR-ICP, NCT03212976: Clinical Efficacy of a Non-Invasive Measure of Intracranial Pressure

Terminated
N/A
11
US
Phase contrast magnetic resonance imaging
University of Miami
Intracranial Pathology, Intracranial Hypertension
10/20
10/20
NCT03780452: Compression Nail for Tibiocalcaneal Arthrodesis

Completed
N/A
30
US
novel dynamic compression intramedullary nail
University of Alabama at Birmingham, MedShape, Inc
Subtalar Arthritis, Ankle Arthritis
07/24
07/24
NCT05047068: OCS Heart Perfusion Post-Approval Registry

Active, not recruiting
N/A
350
US
OCS Heart System
TransMedics
Transplant
12/25
12/29
NCT05881278: XVIVO Heart Perfusion System (XHPS) With Supplemented XVIVO Heart Solution (SXHS)

Active, not recruiting
N/A
141
US
Non-Ischemic Heart Preservation (NIHP) using the XVIVO Heart Preservation System (XHPS)
XVIVO Perfusion
Heart Failure, Transplant; Failure, Heart
11/25
11/29
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
N/A
1056
Europe, Canada, US
Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Medtronic Cardiovascular
Mitral Valve Regurgitation
10/26
09/36
 

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