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18 Trials

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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Eichenbaum, David
DETeR, NCT04563299: Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections	Terminated	4	10	US	Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate	Retina Vitreous Associates of Florida, Ocular Therapeutix, Inc.	Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion	02/23	02/23
ARCHER II, NCT06510816: A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA)	Recruiting	3	630	US	ANX007, Sham Administration	Annexon, Inc.	Geographic Atrophy	10/26	10/27
GION, NCT06178055: A Study of the Efficacy and Safety of KUS121 in Participants With Acute Non-Arteritic Central Retinal Artery Occlusion (CRAO)	Active, not recruiting	2	75	US	KUS121 high dose, KUS121 low dose, Sham procedure	Kyoto Drug Discovery and Development Co., Ltd.	Central Retinal Artery Occlusion	03/25	12/25
SIGLEC, NCT05839041: A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)	Active, not recruiting	2	300	US	AVD-104, Avacincaptad	Aviceda Therapeutics, Inc.	Geographic Atrophy of the Macula, Macular Degeneration	09/25	09/26
NCT06116916: Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema	Recruiting	2	150	Japan, US, RoW	KHK4951, Aflibercept Injection	Kyowa Kirin Co., Ltd.	Diabetic Macular Edema (DME)	11/25	12/25
NCT06116890: Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration	Recruiting	2	180	Japan, US, RoW	KHK4951, Aflibercept Injection	Kyowa Kirin Co., Ltd.	Neovascular Age-Related Macular Degeneration (nAMD)	11/25	12/25
NCT05230537: A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration	Recruiting	2	146	Europe, US, RoW	Iptacopan (LNP023), Placebo	Novartis Pharmaceuticals	Age-Related Macular Degeneration	10/26	10/26
NCT05930561: 4D-150 in Patients With Diabetic Macular Edema	Recruiting	2	72	US	4D-150 IVT, Aflibercept IVT, Eylea	4D Molecular Therapeutics	Diabetic Macular Edema, Diabetic Retinopathy	02/28	07/28
PRISM, NCT05197270: 4D-150 in Patients with Neovascular (Wet) Age-Related Macular Degeneration	Recruiting	1/2	215	US	4D-150 IVT, Aflibercept IVT	4D Molecular Therapeutics	Neovascular (Wet) Age-Related Macular Degeneration	11/25	11/26
Stone, Cameron M
NCT05930561: 4D-150 in Patients With Diabetic Macular Edema	Recruiting	2	72	US	4D-150 IVT, Aflibercept IVT, Eylea	4D Molecular Therapeutics	Diabetic Macular Edema, Diabetic Retinopathy	02/28	07/28
PRISM, NCT05197270: 4D-150 in Patients with Neovascular (Wet) Age-Related Macular Degeneration	Recruiting	1/2	215	US	4D-150 IVT, Aflibercept IVT	4D Molecular Therapeutics	Neovascular (Wet) Age-Related Macular Degeneration	11/25	11/26
Bridges, William
ARCHER II, NCT06510816: A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA)	Recruiting	3	630	US	ANX007, Sham Administration	Annexon, Inc.	Geographic Atrophy	10/26	10/27
NCT04740671 / 2020-005364-57: A Phase 3 Study to Compare the Efficacy and Safety of HLX04-O with Ranibizumab in Subjects with WAMD	Completed	3	410	Europe, US, RoW	HLX04-O, ranibizumab	Shanghai Henlius Biotech	Age Related Macular Degeneration	12/24	12/24
Flores, Flor
SAFE KIDNEY II, NCT05769582: Safety, Tolerability and Efficacy of AntiBKV as Treatment of BKV Infection in Kidney Transplant Recipients	Recruiting	2/3	180	US	Anti-BK polyomavirus (AntiBKV)	Memo Therapeutics AG	BK Viremia; BKV DNAemia	11/24	11/24
CONCERTO, NCT05438732: Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD	Recruiting	N/A	125	US	smaller incision, new generation implantable miniature telescope (SING-IMT)	VisionCare, Inc., ORA, Inc.	Age-Related Macular Degeneration, Geographic Atrophy	12/25	12/25
NCT05074160: OCS Liver Perfusion (OLP) Post-Approval Registry	Active, not recruiting	N/A	166	US	OCS Liver	TransMedics	Liver Transplant	06/25	06/26
Watkins, Vera
PRISM, NCT05197270: 4D-150 in Patients with Neovascular (Wet) Age-Related Macular Degeneration	Recruiting	1/2	215	US	4D-150 IVT, Aflibercept IVT	4D Molecular Therapeutics	Neovascular (Wet) Age-Related Macular Degeneration	11/25	11/26
Hall, McCayla
PRISM, NCT05197270: 4D-150 in Patients with Neovascular (Wet) Age-Related Macular Degeneration	Recruiting	1/2	215	US	4D-150 IVT, Aflibercept IVT	4D Molecular Therapeutics	Neovascular (Wet) Age-Related Macular Degeneration	11/25	11/26