Eichenbaum, David |
DETeR, NCT04563299: Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections |
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| Terminated | 4 | 10 | US | Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate | Retina Vitreous Associates of Florida, Ocular Therapeutix, Inc. | Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion | 02/23 | 02/23 | | |
ARCHER II, NCT06510816: A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA) |
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| Recruiting | 3 | 630 | US | ANX007, Sham Administration | Annexon, Inc. | Geographic Atrophy | 10/26 | 10/27 | | |
GION, NCT06178055: A Study of the Efficacy and Safety of KUS121 in Participants With Acute Non-Arteritic Central Retinal Artery Occlusion (CRAO) |
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| Active, not recruiting | 2 | 75 | US | KUS121 high dose, KUS121 low dose, Sham procedure | Kyoto Drug Discovery and Development Co., Ltd. | Central Retinal Artery Occlusion | 03/25 | 12/25 | | |
SIGLEC, NCT05839041: A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD) |
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| Active, not recruiting | 2 | 300 | US | AVD-104, Avacincaptad | Aviceda Therapeutics, Inc. | Geographic Atrophy of the Macula, Macular Degeneration | 09/25 | 09/26 | | |
NCT06116916: Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema |
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| Recruiting | 2 | 150 | Japan, US, RoW | KHK4951, Aflibercept Injection | Kyowa Kirin Co., Ltd. | Diabetic Macular Edema (DME) | 11/25 | 12/25 | | |
NCT06116890: Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration |
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| Recruiting | 2 | 180 | Japan, US, RoW | KHK4951, Aflibercept Injection | Kyowa Kirin Co., Ltd. | Neovascular Age-Related Macular Degeneration (nAMD) | 11/25 | 12/25 | | |
NCT05230537: A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration |
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| Recruiting | 2 | 146 | Europe, US, RoW | Iptacopan (LNP023), Placebo | Novartis Pharmaceuticals | Age-Related Macular Degeneration | 10/26 | 10/26 | | |
| Recruiting | 2 | 72 | US | 4D-150 IVT, Aflibercept IVT, Eylea | 4D Molecular Therapeutics | Diabetic Macular Edema, Diabetic Retinopathy | 02/28 | 07/28 | | |
| Recruiting | 1/2 | 215 | US | 4D-150 IVT, Aflibercept IVT | 4D Molecular Therapeutics | Neovascular (Wet) Age-Related Macular Degeneration | 11/25 | 11/26 | | |
Stone, Cameron M |
| Recruiting | 2 | 72 | US | 4D-150 IVT, Aflibercept IVT, Eylea | 4D Molecular Therapeutics | Diabetic Macular Edema, Diabetic Retinopathy | 02/28 | 07/28 | | |
| Recruiting | 1/2 | 215 | US | 4D-150 IVT, Aflibercept IVT | 4D Molecular Therapeutics | Neovascular (Wet) Age-Related Macular Degeneration | 11/25 | 11/26 | | |
Bridges, William |
ARCHER II, NCT06510816: A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA) |
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| Recruiting | 3 | 630 | US | ANX007, Sham Administration | Annexon, Inc. | Geographic Atrophy | 10/26 | 10/27 | | |
| Completed | 3 | 410 | Europe, US, RoW | HLX04-O, ranibizumab | Shanghai Henlius Biotech | Age Related Macular Degeneration | 12/24 | 12/24 | | |
Flores, Flor |
| Recruiting | 2/3 | 180 | US | Anti-BK polyomavirus (AntiBKV) | Memo Therapeutics AG | BK Viremia; BKV DNAemia | 11/24 | 11/24 | | |
| Recruiting | N/A | 125 | US | smaller incision, new generation implantable miniature telescope (SING-IMT) | VisionCare, Inc., ORA, Inc. | Age-Related Macular Degeneration, Geographic Atrophy | 12/25 | 12/25 | | |
NCT05074160: OCS Liver Perfusion (OLP) Post-Approval Registry |
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| Active, not recruiting | N/A | 166 | US | OCS Liver | TransMedics | Liver Transplant | 06/25 | 06/26 | | |
Watkins, Vera |
| Recruiting | 1/2 | 215 | US | 4D-150 IVT, Aflibercept IVT | 4D Molecular Therapeutics | Neovascular (Wet) Age-Related Macular Degeneration | 11/25 | 11/26 | | |
Hall, McCayla |
| Recruiting | 1/2 | 215 | US | 4D-150 IVT, Aflibercept IVT | 4D Molecular Therapeutics | Neovascular (Wet) Age-Related Macular Degeneration | 11/25 | 11/26 | | |