Perin, Emerson |
ACORD, NCT00117936: Fibroblast Growth Factor-1 (FGF-1) for the Treatment of Coronary Heart Disease |
|
|
| Not yet recruiting | 2 | 150 | NA | Human Recombinant Fibroblast Growth Factor-1 (FGF 1-141) - low dose, Human Recombinant Fibroblast Growth Factor-1 (FGF1-141) - high dose, Placebo | CardioVascular BioTherapeutics, Inc. | Coronary Disease, Coronary Heart Disease, Myocardial Ischemia, Coronary Arteriosclerosis | 03/22 | 03/23 | | |
CATO, NCT06145035: Single or Repeated Intravenous Administration of umbiliCAl Cord Mesenchymal sTrOmal Cells in Ischemic Cardiomyopathy |
|
|
| Recruiting | 2 | 60 | US | umbilical cord-derived mesenchymal stromal cells (UC-MSCs) | Roberto Bolli, University of Miami, University of Texas, United States Department of Defense | Ischemic Heart Disease | 01/26 | 01/26 | | |
NCT05592275: A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF) |
|
|
| Active, not recruiting | 2 | 456 | Europe, Canada, Japan, US, RoW | LY3540378, Placebo | Eli Lilly and Company | Heart Failure, Heart Failure With Preserved Ejection Fraction | 01/25 | 01/25 | | |
DCMII, NCT04476901: Administration of Allogeneic-MSC in Patients with Non-Ischemic Dilated Cardiomyopathy |
|
|
| Recruiting | 2 | 136 | US | allogeneic human mesenchymal stem cells (hMSCs), Placebo | Joshua M Hare, United States Department of Defense, The University of Texas Health Science Center, Houston | Non-ischemic Dilated Cardiomyopathy | 12/25 | 12/25 | | |
NCT00314366: Intramyocardial Injection of Autologous Aldehyde Dehydrogenase-Bright Stem Cells for Therapeutic Angiogenesis (FOCUS Br) |
|
|
| Completed | 1 | 21 | US | Stem Cell Therapy, NOGA Myostar catheter, Control (plasma) | Texas Heart Institute, CHI St. Luke's Health, Texas, Aldagen | Coronary Artery Disease | 08/09 | 08/23 | | |
| Recruiting | N/A | 380 | Canada, US | Arm 1: treatment with Neovasc Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry | Neovasc Inc., Shockwave Medical, Inc. | Refractory Angina | 06/25 | 12/28 | | |
Civitello, Andrew |
GenePHIT, NCT05598333: Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects with Non-Ischemic NYHA Class III Heart Failure |
|
|
| Recruiting | 2 | 150 | US | AB-1002, Gene Therapy, NAN-101 | Asklepios Biopharmaceutical, Inc. | Congestive Heart Failure | 10/26 | 12/30 | | |