Friedrich-Baur-Institut an der Neurologischen Klinik und Poliklinik
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 10 Trials 
15 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Klopstock, Thomas
NCT04604548: The KHENEREXT Study

Completed
2
11
Europe
Oral administration of 100 mg KH176 twice daily
Khondrion BV, Julius Clinical, ProPharma Group, Certara
Mitochondrial Diseases, Mitochondrial DNA tRNALeu(UUR) m.3243A
06/23
06/23
STRIDE, NCT04535609 / 2020-002855-40: An Efficacy and Safety Study of 24 Week Treatment With Mavodelpar (REN001) in Primary Mitochondrial Myopathy Patients

Completed
2
213
Europe, Canada, US, RoW
Mavodelpar, REN001, Placebo
Reneo Pharma Ltd
Primary Mitochondrial Myopathy
09/23
10/23
PMD-OPTION, NCT05972954 / 2022-003307-16: OMT-28 in Patients With Primary Mitochondrial Disease (PMD)

Active, not recruiting
2
32
Europe
OMT-28
Omeicos Therapeutics GmbH, OMEICOS Therapeutics GmbH
Primary Mitochondrial Disease
03/25
06/25
PROFA, NCT05943002: Patient-reported, Health Economic and Psychosocial Outcomes in Friedreich Ataxia

Recruiting
N/A
200
Europe
German Center for Neurodegenerative Diseases (DZNE), McMaster University, Sorbonne University
Friedreich Ataxia
08/24
10/24
EFACTS, NCT02069509: Patient Registry of the European Friedreich's Ataxia Consortium for Translational Studies

Recruiting
N/A
1200
Europe, RoW
European Friedreich's Ataxia Consortium for Translational Studies
Friedreich's Ataxia
12/24
12/24
SPORTAX-NHS, NCT02701036: Sporadic Degenerative Ataxia With Adult Onset: Natural History Study

Recruiting
N/A
300
Europe
Ataxia Study Group, German Center for Neurodegenerative Diseases (DZNE)
Late Onset Sporadic Cerebellar Ataxia
12/30
12/30
HSP-PBP, NCT03981276: Phenotypes, Biomarkers and Pathophysiology in Hereditary Spastic Paraplegias and Related Disorders

Recruiting
N/A
2000
Europe
Clinical rating scale to measure disease severity and progression, Spastic Paraplegia Rating Scale (SPRS), Next-Gen Sequencing (NGS)
Dr. Rebecca Schule, German Federal Ministry of Education and Research, German Center for Neurodegenerative Diseases (DZNE)
Hereditary Spastic Paraplegia
08/39
08/41
UNIFAI, NCT06016946: Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

Recruiting
N/A
3000
Europe, Canada, US, RoW
Friedreich's Ataxia Research Alliance
Friedreich Ataxia
01/48
01/48
NCT05554835: Global Registry and Natural History Study for Mitochondrial Disorders

Recruiting
N/A
6000
Europe
LMU Klinikum, European Commission, German Federal Ministry of Education and Research, University of Pisa
Mitochondrial Diseases, Kearns-Sayre Syndrome, MIDD, SANDO, SCAE, NARP Syndrome, MELAS Syndrome, MERRF Syndrome, Coenzyme Q10 Deficiency, LHON, MNGIE, MIRAS, Barth Syndrome, MDS, Mitochondrial Myopathies, Leigh Syndrome, Pearson Syndrome, CPEO
12/40
12/40
TIRCON, NCT05522374: International NBIA Registry

Recruiting
N/A
2000
Europe, Canada, RoW
LMU Klinikum, Seventh Framework Programme, NBIA Alliance
Neurodegeneration With Brain Iron Accumulation (NBIA), Pantothenate Kinase-associated Neurodegeneration (PKAN), Beta-Propeller Protein-Associated Neurodegeneration (BPAN), Mitochondrial Membrane Protein Associated Neurodegeneration (MPAN), Fatty Acid Hydroxylase-associated Neurodegeneration (FAHN), Kufor Rakeb Syndrome, Neuroferritinopathy, Aceruloplasminemia, Woodhouse Sakati Syndrome, COASY Protein-associated Neurodegeneration (CoPAN), PLA2G6-Associated Neurodegeneration (PLAN)
12/40
12/40
Reetz, Kathrin
PROFA, NCT05943002: Patient-reported, Health Economic and Psychosocial Outcomes in Friedreich Ataxia

Recruiting
N/A
200
Europe
German Center for Neurodegenerative Diseases (DZNE), McMaster University, Sorbonne University
Friedreich Ataxia
08/24
10/24
EFACTS, NCT02069509: Patient Registry of the European Friedreich's Ataxia Consortium for Translational Studies

Recruiting
N/A
1200
Europe, RoW
European Friedreich's Ataxia Consortium for Translational Studies
Friedreich's Ataxia
12/24
12/24
TRACK-FA, NCT04349514: A Natural History Study to TRACK Brain and Spinal Cord Changes in Individuals With Friedreich Ataxia

Active, not recruiting
N/A
300
Europe, Canada, US, RoW
Natural history
Monash University, University of Minnesota, RWTH Aachen University, University of Campinas, Brazil, Children's Hospital of Philadelphia, University of Florida, Friedreich's Ataxia Research Alliance, McGill University
Friedreich Ataxia
08/25
08/25
UNIFAI, NCT06016946: Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

Recruiting
N/A
3000
Europe, Canada, US, RoW
Friedreich's Ataxia Research Alliance
Friedreich Ataxia
01/48
01/48
NCT01574053: Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

Recruiting
N/A
35000
Europe, Canada, US, RoW
CHDI Foundation, Inc.
Huntington's Disease
01/62
01/62

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