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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Valipour, Arschang
BLOC, NCT05911009 / 2022-003452-14: To Investigate Efficacy, Pharmacodynamics, and Safety of BC 007 in Participants With Long COVID	Completed	2	119	Europe	BC 007 or matching placebo	Berlin Cures GmbH, Berlin Cures GmbH	Long Covid	06/24	09/24
NCT06035120: An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients with Severe Emphysema	Recruiting	N/A	200	Europe, US, RoW	AeriSeal System	Pulmonx Corporation	Emphysema, Pulmonary, Emphysema or COPD	06/27	03/28
NCT06522334: Interstitial Lung Disease Registry Study: Prospective and Retrospective Observational Study in Austria	Recruiting	N/A	400	Europe		Ludwig Boltzmann Institute for Lung Health	Interstitial Lung Disease	02/34	02/34
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis	Active, not recruiting	N/A	270	Europe, US	RheOx Bronchial Rheoplasty, Sham Procedure	Gala Therapeutics, Inc.	Chronic Bronchitis	05/24	10/25
AIRFLOW-3, NCT03639051: Evaluation of the Safety and Efficacy of TLD in Patients with COPD	Active, not recruiting	N/A	464	Europe, US	Targeted Lung Denervation (TLD), TLD, TLD Therapy, Optimal Medical Care	Nuvaira, Inc.	COPD	10/24	09/28
NCT04182841: RheOx Registry Study in Europe	Recruiting	N/A	100	Europe	RheOx	Gala Therapeutics, Inc.	Chronic Bronchitis, COPD	12/24	12/25
NCT06655428: The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema	Recruiting	N/A	30	Europe	Endobronchial Therman Liquid Ablation (ETLA), Bronchoscopic lung volume reduction	Morair Medtech, LLC	Emphysema or COPD, Emphysema, Emphysema, Pulmonary, COPD, COPD (Chronic Obstructive Pulmonary Disease)	02/26	05/26
BREATHE-2, NCT05949645: Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema	Active, not recruiting	N/A	30	Europe	Apreo Implant Group	Apreo Health, Inc.	Emphysema or COPD	10/24	06/26
NCT03318406: Post-Market BTVA Registry	Recruiting	N/A	300	Europe	Bronchoscopic Thermal Vapor Ablation, BTVA, InterVapor	Uptake Medical Technology, Inc.	Emphysema or COPD	12/27	12/30
VAPORIZED, NCT03514329: Vapor Ablation for Localized Cancer Lesions	Not yet recruiting	N/A	10	Europe	Bronchoscopic Thermal Vapor Ablation, BTVA-C	Uptake Medical Technology, Inc.	Non Small Cell Lung Cancer, Metastatic Lung Cancer, Lung Cancer	03/28	06/28
Slebos, Dirk-Jan
EFFORT, NCT04520152: Evaluation of the Free Flow Medical Lung Tensioning Device System for the Treatment of Severe Emphysema	Completed	N/A	14	Europe	FreeFlowMedical Lung Tensioning Device	University Medical Center Groningen	Emphysema or COPD	11/23	11/23
SOLVE, NCT03474471: A Trial on the Effects of Bronchoscopic Lung Volume Reduction in Severe Emphysema.	Completed	N/A	96	Europe	Pulmonary rehabilitation, EBV treatment	University Medical Center Groningen, Maastricht University Medical Center, Center of Expertise for Chronic Organ Failure	Emphysema	04/23	04/23
CONVERT, NCT04559464: Fissure Closure With the AeriSeal System for ing Collateral Ventilation Status	Completed	N/A	102	Europe, RoW	AeriSeal, Zephyr Valves, Bronchoscopic Lung Volume Reduction (BLVR), Zephyr System	Pulmonx Corporation	Emphysema, COPD, Severe Emphysema	10/23	10/24
NCT06035120: An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients with Severe Emphysema	Recruiting	N/A	200	Europe, US, RoW	AeriSeal System	Pulmonx Corporation	Emphysema, Pulmonary, Emphysema or COPD	06/27	03/28
DIAMANT, NCT04735731: Assessing the DIAphragM Before ANd After Endobronchial Valve Treatment	Completed	N/A	25	Europe	Echography	University Medical Center Groningen	Emphysema	02/24	02/24
IAB-1, NCT05087641: A Multicenter, Prospective Trial of the IAB in Adults Suffering From COPD/Emphysema	Active, not recruiting	N/A	20	Europe, RoW	IAB System	Pulmair Medical, Inc.	Emphysema, Pulmonary Disease, Chronic Obstructive	04/24	01/27
Bio-EXCEL, NCT04214587: Biological Investigation of Explanted Endobronchial Lung Valves Study	Recruiting	N/A	150	Europe	tissue and blood sampling	University Medical Center Groningen	Emphysema or COPD	03/27	03/27
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis	Active, not recruiting	N/A	270	Europe, US	RheOx Bronchial Rheoplasty, Sham Procedure	Gala Therapeutics, Inc.	Chronic Bronchitis	05/24	10/25
AIRFLOW-3, NCT03639051: Evaluation of the Safety and Efficacy of TLD in Patients with COPD	Active, not recruiting	N/A	464	Europe, US	Targeted Lung Denervation (TLD), TLD, TLD Therapy, Optimal Medical Care	Nuvaira, Inc.	COPD	10/24	09/28
NCT06655428: The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema	Recruiting	N/A	30	Europe	Endobronchial Therman Liquid Ablation (ETLA), Bronchoscopic lung volume reduction	Morair Medtech, LLC	Emphysema or COPD, Emphysema, Emphysema, Pulmonary, COPD, COPD (Chronic Obstructive Pulmonary Disease)	02/26	05/26
BREATHE-2, NCT05949645: Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema	Active, not recruiting	N/A	30	Europe	Apreo Implant Group	Apreo Health, Inc.	Emphysema or COPD	10/24	06/26
ENDURANCE, NCT06025500: Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve Treatment	Recruiting	N/A	15	Europe	31P-Magnetic Resonance Spectroscopy (31P-MRS), Muscle biopsy	University Medical Center Groningen	Emphysema	12/25	12/25
BREATHE-NL, NCT02815683: Bronchoscopic EmphysemA Treatment in THE NetherLands	Recruiting	N/A	500	Europe		University Medical Center Groningen	COPD	01/28	01/28
NAVIGATOR, NCT05383105: Virtual Bronchoscopic Navigation to Increase Diagnostic Yield in Patients With Pulmonary Nodules	Recruiting	N/A	100	Europe	Virtual bronchoscopic navigation, Archimedes	University Medical Center Groningen	Pulmonary Nodules, Solitary	05/26	05/26
Hartman, Jorine
CONVERT, NCT04559464: Fissure Closure With the AeriSeal System for ing Collateral Ventilation Status	Completed	N/A	102	Europe, RoW	AeriSeal, Zephyr Valves, Bronchoscopic Lung Volume Reduction (BLVR), Zephyr System	Pulmonx Corporation	Emphysema, COPD, Severe Emphysema	10/23	10/24
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis	Active, not recruiting	N/A	270	Europe, US	RheOx Bronchial Rheoplasty, Sham Procedure	Gala Therapeutics, Inc.	Chronic Bronchitis	05/24	10/25
AIRFLOW-3, NCT03639051: Evaluation of the Safety and Efficacy of TLD in Patients with COPD	Active, not recruiting	N/A	464	Europe, US	Targeted Lung Denervation (TLD), TLD, TLD Therapy, Optimal Medical Care	Nuvaira, Inc.	COPD	10/24	09/28
RELIEF, NCT05938738: PEP-buddy in COPD: Effect on Dyspnea Severity and Mechanism of Action	Recruiting	N/A	25	Europe	PEP-buddy	University Medical Center Groningen	COPD	12/25	12/25
CROCODILE, NCT06702072: Change in Task-related Oxygen Uptake After EBV Treatment	Not yet recruiting	N/A	20	Europe	Endobronchial valve treatment	Dirk-Jan Slebos	COPD	08/26	08/26
ENDURANCE, NCT06025500: Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve Treatment	Recruiting	N/A	15	Europe	31P-Magnetic Resonance Spectroscopy (31P-MRS), Muscle biopsy	University Medical Center Groningen	Emphysema	12/25	12/25

Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Valipour, Arschang
BLOC, NCT05911009 / 2022-003452-14: To Investigate Efficacy, Pharmacodynamics, and Safety of BC 007 in Participants With Long COVID	Completed	2	119	Europe	BC 007 or matching placebo	Berlin Cures GmbH, Berlin Cures GmbH	Long Covid	06/24	09/24
NCT06035120: An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients with Severe Emphysema	Recruiting	N/A	200	Europe, US, RoW	AeriSeal System	Pulmonx Corporation	Emphysema, Pulmonary, Emphysema or COPD	06/27	03/28
NCT06522334: Interstitial Lung Disease Registry Study: Prospective and Retrospective Observational Study in Austria	Recruiting	N/A	400	Europe		Ludwig Boltzmann Institute for Lung Health	Interstitial Lung Disease	02/34	02/34
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis	Active, not recruiting	N/A	270	Europe, US	RheOx Bronchial Rheoplasty, Sham Procedure	Gala Therapeutics, Inc.	Chronic Bronchitis	05/24	10/25
AIRFLOW-3, NCT03639051: Evaluation of the Safety and Efficacy of TLD in Patients with COPD	Active, not recruiting	N/A	464	Europe, US	Targeted Lung Denervation (TLD), TLD, TLD Therapy, Optimal Medical Care	Nuvaira, Inc.	COPD	10/24	09/28
NCT04182841: RheOx Registry Study in Europe	Recruiting	N/A	100	Europe	RheOx	Gala Therapeutics, Inc.	Chronic Bronchitis, COPD	12/24	12/25
NCT06655428: The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema	Recruiting	N/A	30	Europe	Endobronchial Therman Liquid Ablation (ETLA), Bronchoscopic lung volume reduction	Morair Medtech, LLC	Emphysema or COPD, Emphysema, Emphysema, Pulmonary, COPD, COPD (Chronic Obstructive Pulmonary Disease)	02/26	05/26
BREATHE-2, NCT05949645: Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema	Active, not recruiting	N/A	30	Europe	Apreo Implant Group	Apreo Health, Inc.	Emphysema or COPD	10/24	06/26
NCT03318406: Post-Market BTVA Registry	Recruiting	N/A	300	Europe	Bronchoscopic Thermal Vapor Ablation, BTVA, InterVapor	Uptake Medical Technology, Inc.	Emphysema or COPD	12/27	12/30
VAPORIZED, NCT03514329: Vapor Ablation for Localized Cancer Lesions	Not yet recruiting	N/A	10	Europe	Bronchoscopic Thermal Vapor Ablation, BTVA-C	Uptake Medical Technology, Inc.	Non Small Cell Lung Cancer, Metastatic Lung Cancer, Lung Cancer	03/28	06/28
Slebos, Dirk-Jan
EFFORT, NCT04520152: Evaluation of the Free Flow Medical Lung Tensioning Device System for the Treatment of Severe Emphysema	Completed	N/A	14	Europe	FreeFlowMedical Lung Tensioning Device	University Medical Center Groningen	Emphysema or COPD	11/23	11/23
SOLVE, NCT03474471: A Trial on the Effects of Bronchoscopic Lung Volume Reduction in Severe Emphysema.	Completed	N/A	96	Europe	Pulmonary rehabilitation, EBV treatment	University Medical Center Groningen, Maastricht University Medical Center, Center of Expertise for Chronic Organ Failure	Emphysema	04/23	04/23
CONVERT, NCT04559464: Fissure Closure With the AeriSeal System for ing Collateral Ventilation Status	Completed	N/A	102	Europe, RoW	AeriSeal, Zephyr Valves, Bronchoscopic Lung Volume Reduction (BLVR), Zephyr System	Pulmonx Corporation	Emphysema, COPD, Severe Emphysema	10/23	10/24
NCT06035120: An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients with Severe Emphysema	Recruiting	N/A	200	Europe, US, RoW	AeriSeal System	Pulmonx Corporation	Emphysema, Pulmonary, Emphysema or COPD	06/27	03/28
DIAMANT, NCT04735731: Assessing the DIAphragM Before ANd After Endobronchial Valve Treatment	Completed	N/A	25	Europe	Echography	University Medical Center Groningen	Emphysema	02/24	02/24
IAB-1, NCT05087641: A Multicenter, Prospective Trial of the IAB in Adults Suffering From COPD/Emphysema	Active, not recruiting	N/A	20	Europe, RoW	IAB System	Pulmair Medical, Inc.	Emphysema, Pulmonary Disease, Chronic Obstructive	04/24	01/27
Bio-EXCEL, NCT04214587: Biological Investigation of Explanted Endobronchial Lung Valves Study	Recruiting	N/A	150	Europe	tissue and blood sampling	University Medical Center Groningen	Emphysema or COPD	03/27	03/27
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis	Active, not recruiting	N/A	270	Europe, US	RheOx Bronchial Rheoplasty, Sham Procedure	Gala Therapeutics, Inc.	Chronic Bronchitis	05/24	10/25
AIRFLOW-3, NCT03639051: Evaluation of the Safety and Efficacy of TLD in Patients with COPD	Active, not recruiting	N/A	464	Europe, US	Targeted Lung Denervation (TLD), TLD, TLD Therapy, Optimal Medical Care	Nuvaira, Inc.	COPD	10/24	09/28
NCT06655428: The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema	Recruiting	N/A	30	Europe	Endobronchial Therman Liquid Ablation (ETLA), Bronchoscopic lung volume reduction	Morair Medtech, LLC	Emphysema or COPD, Emphysema, Emphysema, Pulmonary, COPD, COPD (Chronic Obstructive Pulmonary Disease)	02/26	05/26
BREATHE-2, NCT05949645: Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema	Active, not recruiting	N/A	30	Europe	Apreo Implant Group	Apreo Health, Inc.	Emphysema or COPD	10/24	06/26
ENDURANCE, NCT06025500: Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve Treatment	Recruiting	N/A	15	Europe	31P-Magnetic Resonance Spectroscopy (31P-MRS), Muscle biopsy	University Medical Center Groningen	Emphysema	12/25	12/25
BREATHE-NL, NCT02815683: Bronchoscopic EmphysemA Treatment in THE NetherLands	Recruiting	N/A	500	Europe		University Medical Center Groningen	COPD	01/28	01/28
NAVIGATOR, NCT05383105: Virtual Bronchoscopic Navigation to Increase Diagnostic Yield in Patients With Pulmonary Nodules	Recruiting	N/A	100	Europe	Virtual bronchoscopic navigation, Archimedes	University Medical Center Groningen	Pulmonary Nodules, Solitary	05/26	05/26
Hartman, Jorine
CONVERT, NCT04559464: Fissure Closure With the AeriSeal System for ing Collateral Ventilation Status	Completed	N/A	102	Europe, RoW	AeriSeal, Zephyr Valves, Bronchoscopic Lung Volume Reduction (BLVR), Zephyr System	Pulmonx Corporation	Emphysema, COPD, Severe Emphysema	10/23	10/24
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis	Active, not recruiting	N/A	270	Europe, US	RheOx Bronchial Rheoplasty, Sham Procedure	Gala Therapeutics, Inc.	Chronic Bronchitis	05/24	10/25
AIRFLOW-3, NCT03639051: Evaluation of the Safety and Efficacy of TLD in Patients with COPD	Active, not recruiting	N/A	464	Europe, US	Targeted Lung Denervation (TLD), TLD, TLD Therapy, Optimal Medical Care	Nuvaira, Inc.	COPD	10/24	09/28
RELIEF, NCT05938738: PEP-buddy in COPD: Effect on Dyspnea Severity and Mechanism of Action	Recruiting	N/A	25	Europe	PEP-buddy	University Medical Center Groningen	COPD	12/25	12/25
CROCODILE, NCT06702072: Change in Task-related Oxygen Uptake After EBV Treatment	Not yet recruiting	N/A	20	Europe	Endobronchial valve treatment	Dirk-Jan Slebos	COPD	08/26	08/26
ENDURANCE, NCT06025500: Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve Treatment	Recruiting	N/A	15	Europe	31P-Magnetic Resonance Spectroscopy (31P-MRS), Muscle biopsy	University Medical Center Groningen	Emphysema	12/25	12/25