UBC Children's Hospital Research Institute
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 2 Trials 
9 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Connolly, Mary
ARGUS, NCT04462770 / 2021-003425-30: A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

Recruiting
2
100
Europe, Canada, US, RoW
EPX-100 (clemizole HCl), Placebo
Epygenix, Harmony Biosciences, LLC
Dravet Syndrome
04/26
05/26
RAD-GRIN-201, NCT06392009: Astroscape: a Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients with TSC or FCD Type II

Recruiting
1/2
30
Europe, Canada, RoW
Radiprodil
GRIN Therapeutics, Inc.
Tuberous Sclerosis Complex, Focal Cortical Dysplasia
07/25
07/26
NCT05818943 / 2022-000317-14: Honeycomb: Evaluation of Radiprodil in Children with GRIN-related Disorder

Active, not recruiting
1
24
Europe, Canada, US, RoW
Radiprodil
GRIN Therapeutics, Inc., GRIN Therapeutics, Inc.
GRIN-related Disorders
11/26
11/26
DTU-STEMI, NCT03947619: Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: the STEMI-DTU Trial

Active, not recruiting
N/A
527
Europe, Canada, US
Impella CP® placement prior to reperfusion with Primary PCI
Abiomed Inc.
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
09/24
10/30
Gill, Inderpal
ARGUS, NCT04462770 / 2021-003425-30: A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

Recruiting
2
100
Europe, Canada, US, RoW
EPX-100 (clemizole HCl), Placebo
Epygenix, Harmony Biosciences, LLC
Dravet Syndrome
04/26
05/26
NCT04507997: Angelman Syndrome Natural History Study

Recruiting
N/A
300
Canada, US
Boston Children's Hospital, University of California, San Diego, Angelman Syndrome Biomarker & Outcome Measure Consortium (A-BOM), Food and Drug Administration (FDA), Angelman Syndrome Foundation Canada, Foundation for Angelman Syndrome Therapeutics Canada, Foundation for Angelman Syndrome Therapeutics, Angelman Syndrome Foundation, Inc.
Angelman Syndrome
08/25
08/25
Knight, Elia Pestana
ARGUS, NCT04462770 / 2021-003425-30: A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

Recruiting
2
100
Europe, Canada, US, RoW
EPX-100 (clemizole HCl), Placebo
Epygenix, Harmony Biosciences, LLC
Dravet Syndrome
04/26
05/26
CANDID, NCT05373719: Observational Study in Patients With Cyclin-dependent Kinase-like 5 Deficiency Disorder

Active, not recruiting
N/A
112
Europe, Canada, US, RoW
No intervention; observational
Loulou Foundation
Cyclin-Dependent Kinase-Like 5 Deficiency Disorder
01/27
01/27
ICCRN, NCT05558371: International CDKL5 Clinical Research Network

Recruiting
N/A
1000
US, RoW
No intervention.
University of Colorado, Denver, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), International Foundation for CDKL5 Research
CDKL5, CDKL5 Deficiency Disorder, CDD
02/26
02/27

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