Psychoneuroendocrine Research Program
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 3 Trials 
15 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Brown, Sherwood
NCT03896659: Exploring the Effects of Corticosteroids on the Human Hippocampus

Completed
4
66
US
Hydrocortisone Oral, Placebo Oral Tablet
University of Texas Southwestern Medical Center, University of California, Irvine, National Institute of Mental Health (NIMH)
Hydrocortisone, Depression, Healthy Volunteers
09/24
09/24
NCT03383874: A Probiotic Intervention to Prevent Relapse Following Hospitalization for Mania

Active, not recruiting
3
66
US
Probio-Tec BG-VCap-6.5, Placebo
University of Texas Southwestern Medical Center
Mania (Neurotic)
12/24
07/25
NCT06216535: Escitalopram in Asthma Patients with Frequent Exacerbation

Not yet recruiting
2
105
US
Escitalopram, Placebo
University of Texas Southwestern Medical Center, National Heart, Lung, and Blood Institute (NHLBI)
Asthma
12/28
06/29
NCT03505905: A Neurosteroid Intervention for Menopausal and Perimenopausal Depression

Completed
1/2
123
US
Pregnenolone, Placebo
University of Texas Southwestern Medical Center, Massachusetts General Hospital
Major Depressive Disorder, Menopause, Perimenopause
12/24
12/24
Brown, E Sherwood
NCT02582905: Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

Completed
4
96
US
Placebo, Sugar pill, Citicoline, CDP-Choline, cytidine diphosphate-choline, Pregnenolone, pregn-5-en-3β-ol-20-one
Sherwood Brown, MD, PhD, University of Miami, University of Texas Rio Grande Valley
Alcohol Use Disorder, Bipolar Disorder, Schizoaffective Disorder Bipolar Type
05/23
05/23
NCT02918370: Aripiprazole for Bipolar Disorder and Alcohol Use Disorder

Completed
3
75
US
Aripiprazole, Abilify, Placebo, Sugar Pill
University of Texas Southwestern Medical Center
Bipolar Disorder, Alcoholism, Alcohol Abuse
06/23
06/23
NCT03794856: The Dallas Asthma Brain and Cognition (ABC) Study

Recruiting
N/A
192
US
Functional and Structural Magnetic Resonance Imaging (research grade), Cognitive Function Testing (non-diagnostic), Asthma and Psychological Questionnaires (non-diagnostic)
University of Texas Southwestern Medical Center, Southern Methodist University
Asthma
06/25
06/25
Quemado, Josie Anne Vita
ADHD, NCT06215144: Study to Evaluate NRCT-101SR in Pediatric Subjects with

Recruiting
2/3
160
US
NRCT-101SR, Matching Placebo
Neurocentria, Inc.
Attention-Deficit/Hyperactivity Disorder (ADHD)
12/25
02/26
OSPREY, NCT04950894: Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation

Active, not recruiting
N/A
150
US
Hypoglossal Nerve Stimulation
LivaNova
Obstructive Sleep Apnea, OSA, Apnea, Apnea, Obstructive, Apnea, Obstructive Sleep, Apnea+Hypopnea, Hypopnea, Sleep
10/24
10/25
Shrestha, Salina
CHIPS, NCT04834414: CHIlled Platelet Study ""

Completed
3
1000
US, RoW
Cold Stored Platelets, Room Temperature Platelets
Philip Spinella, University of Utah, University of Minnesota, Washington University School of Medicine, United States Department of Defense, University of Pittsburgh
Acute Blood Loss
03/25
04/25
NCT03383874: A Probiotic Intervention to Prevent Relapse Following Hospitalization for Mania

Active, not recruiting
3
66
US
Probio-Tec BG-VCap-6.5, Placebo
University of Texas Southwestern Medical Center
Mania (Neurotic)
12/24
07/25
LeAAPS, NCT05478304: Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

Recruiting
N/A
6500
Europe, Canada, US, RoW
AtriClip LAA Exclusion System
AtriCure, Inc., Population Health Research Institute
Ischemic Stroke, Systemic Embolism
12/31
04/32
Cabrera-Aguirre, Alejandro
NCT02582905: Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

Completed
4
96
US
Placebo, Sugar pill, Citicoline, CDP-Choline, cytidine diphosphate-choline, Pregnenolone, pregn-5-en-3β-ol-20-one
Sherwood Brown, MD, PhD, University of Miami, University of Texas Rio Grande Valley
Alcohol Use Disorder, Bipolar Disorder, Schizoaffective Disorder Bipolar Type
05/23
05/23
NCT03383874: A Probiotic Intervention to Prevent Relapse Following Hospitalization for Mania

Active, not recruiting
3
66
US
Probio-Tec BG-VCap-6.5, Placebo
University of Texas Southwestern Medical Center
Mania (Neurotic)
12/24
07/25
NCT06216535: Escitalopram in Asthma Patients with Frequent Exacerbation

Not yet recruiting
2
105
US
Escitalopram, Placebo
University of Texas Southwestern Medical Center, National Heart, Lung, and Blood Institute (NHLBI)
Asthma
12/28
06/29
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Brown, Sherwood
NCT03896659: Exploring the Effects of Corticosteroids on the Human Hippocampus

Completed
4
66
US
Hydrocortisone Oral, Placebo Oral Tablet
University of Texas Southwestern Medical Center, University of California, Irvine, National Institute of Mental Health (NIMH)
Hydrocortisone, Depression, Healthy Volunteers
09/24
09/24
NCT03383874: A Probiotic Intervention to Prevent Relapse Following Hospitalization for Mania

Active, not recruiting
3
66
US
Probio-Tec BG-VCap-6.5, Placebo
University of Texas Southwestern Medical Center
Mania (Neurotic)
12/24
07/25
NCT06216535: Escitalopram in Asthma Patients with Frequent Exacerbation

Not yet recruiting
2
105
US
Escitalopram, Placebo
University of Texas Southwestern Medical Center, National Heart, Lung, and Blood Institute (NHLBI)
Asthma
12/28
06/29
NCT03505905: A Neurosteroid Intervention for Menopausal and Perimenopausal Depression

Completed
1/2
123
US
Pregnenolone, Placebo
University of Texas Southwestern Medical Center, Massachusetts General Hospital
Major Depressive Disorder, Menopause, Perimenopause
12/24
12/24
Brown, E Sherwood
NCT02582905: Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

Completed
4
96
US
Placebo, Sugar pill, Citicoline, CDP-Choline, cytidine diphosphate-choline, Pregnenolone, pregn-5-en-3β-ol-20-one
Sherwood Brown, MD, PhD, University of Miami, University of Texas Rio Grande Valley
Alcohol Use Disorder, Bipolar Disorder, Schizoaffective Disorder Bipolar Type
05/23
05/23
NCT02918370: Aripiprazole for Bipolar Disorder and Alcohol Use Disorder

Completed
3
75
US
Aripiprazole, Abilify, Placebo, Sugar Pill
University of Texas Southwestern Medical Center
Bipolar Disorder, Alcoholism, Alcohol Abuse
06/23
06/23
NCT03794856: The Dallas Asthma Brain and Cognition (ABC) Study

Recruiting
N/A
192
US
Functional and Structural Magnetic Resonance Imaging (research grade), Cognitive Function Testing (non-diagnostic), Asthma and Psychological Questionnaires (non-diagnostic)
University of Texas Southwestern Medical Center, Southern Methodist University
Asthma
06/25
06/25
Quemado, Josie Anne Vita
ADHD, NCT06215144: Study to Evaluate NRCT-101SR in Pediatric Subjects with

Recruiting
2/3
160
US
NRCT-101SR, Matching Placebo
Neurocentria, Inc.
Attention-Deficit/Hyperactivity Disorder (ADHD)
12/25
02/26
OSPREY, NCT04950894: Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation

Active, not recruiting
N/A
150
US
Hypoglossal Nerve Stimulation
LivaNova
Obstructive Sleep Apnea, OSA, Apnea, Apnea, Obstructive, Apnea, Obstructive Sleep, Apnea+Hypopnea, Hypopnea, Sleep
10/24
10/25
Shrestha, Salina
CHIPS, NCT04834414: CHIlled Platelet Study ""

Completed
3
1000
US, RoW
Cold Stored Platelets, Room Temperature Platelets
Philip Spinella, University of Utah, University of Minnesota, Washington University School of Medicine, United States Department of Defense, University of Pittsburgh
Acute Blood Loss
03/25
04/25
NCT03383874: A Probiotic Intervention to Prevent Relapse Following Hospitalization for Mania

Active, not recruiting
3
66
US
Probio-Tec BG-VCap-6.5, Placebo
University of Texas Southwestern Medical Center
Mania (Neurotic)
12/24
07/25
LeAAPS, NCT05478304: Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

Recruiting
N/A
6500
Europe, Canada, US, RoW
AtriClip LAA Exclusion System
AtriCure, Inc., Population Health Research Institute
Ischemic Stroke, Systemic Embolism
12/31
04/32
Cabrera-Aguirre, Alejandro
NCT02582905: Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

Completed
4
96
US
Placebo, Sugar pill, Citicoline, CDP-Choline, cytidine diphosphate-choline, Pregnenolone, pregn-5-en-3β-ol-20-one
Sherwood Brown, MD, PhD, University of Miami, University of Texas Rio Grande Valley
Alcohol Use Disorder, Bipolar Disorder, Schizoaffective Disorder Bipolar Type
05/23
05/23
NCT03383874: A Probiotic Intervention to Prevent Relapse Following Hospitalization for Mania

Active, not recruiting
3
66
US
Probio-Tec BG-VCap-6.5, Placebo
University of Texas Southwestern Medical Center
Mania (Neurotic)
12/24
07/25
NCT06216535: Escitalopram in Asthma Patients with Frequent Exacerbation

Not yet recruiting
2
105
US
Escitalopram, Placebo
University of Texas Southwestern Medical Center, National Heart, Lung, and Blood Institute (NHLBI)
Asthma
12/28
06/29

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