| Plantefeve, Gaetan |
MARIO, NCT05178862 / 2022-000648-32: A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole |
|
|
| Suspended | 3 | 220 | Europe, Canada, US, RoW | SCY-078, Ibrexafungerp, Fluconazole, Diflucan, Echinocandin, Caspofungin, Micafungin, Anidulafungin | Scynexis, Inc., SCYNEXIS, Inc. | Candidiasis, Invasive, Candidemia | 06/24 | 08/24 | | |
REITAB-2, NCT05204563: Imipenem/Cilastatin-XNW4107 Versus Imipenem/Cilastatin/Relebactam for Treatment of Participants With Bacterial Pneumonia (XNW4107-302, ) |
|
|
| Recruiting | 3 | 450 | Europe, US, RoW | Combination of Imipenem/Cilastatin and XNW4107, Imipenem/Cilastatin/Relebactam, Recarbrio | Evopoint Biosciences Inc. | Hospital Acquired Bacterial Pneumonia or Ventilator-Associated Bacterial Pneumonia | 04/25 | 12/25 | | |
PLATINIUM, NCT06774235: Prevention of Secondary Infections by Interferon Gamma in ICU-acquired Sustained Immune-suppression |
|
|
| Not yet recruiting | 3 | 326 | Europe | Interferon Gamma 1-b, Placebo | University Hospital, Limoges | Sustained Immunosuppression | 09/28 | 09/28 | | |
NCT04612413: A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients |
|
|
| Active, not recruiting | 2 | 160 | Europe, RoW | Allocetra-OTS, Placebo | Enlivex Therapeutics Ltd., Cato Research, Accelsiors CRO & Consultancy Services | Sepsis, Community-acquired Pneumonia, Urinary Tract Infections, Cholecystitis, Acute, Cholangitis Acute, Intraabdominal Infections | 12/24 | 03/25 | | |
NCT05962606: Safety and Efficacy of AON-D21 in Severe Community-Acquired Pneumonia. |
|
|
| Recruiting | 2 | 150 | Europe | AON-D21, Placebo | Aptarion Biotech AG | Community-acquired Pneumonia | 05/26 | 06/26 | | |
| Completed | N/A | 1346 | Europe, RoW | Family members of patients admitted to the ICU, Health care professionals, Patients | Nantes University Hospital, Assistance Publique - Hôpitaux de Paris, Assistance Publique Hopitaux De Marseille | Stress Disorders, Post-Traumatic, Family Members | 01/24 | 09/24 | | |
EXSUPEEP, NCT05147636: EXtubation With SUctioning or With Positive End-Expiratory Pressure in Intensive Care Unit |
|
|
| Recruiting | N/A | 424 | Europe | Extubation with PEEP, Endotracheal Aspiration | Centre Hospitalier de Bourg en Bresse, Direction Générale de l'Offre de Soins, Hospices Civils de Lyon | Extubation in Intensive Care Unit | 06/25 | 07/25 | | |
| Recruiting | N/A | 740 | Europe, Canada, US, RoW | Respiratory Mechanics, Standard Ventilation Strategy | Unity Health Toronto, Canadian Institutes of Health Research (CIHR), University of Toronto, Applied Health Research Centre | ARDS | 11/25 | 03/26 | | |
RECOVER_FU, NCT05890560: Two-year Efficacy of Three Exercise Rehabilitation Strategies on Dyspnea in Patients Who Presented With Secondary Respiratory Distress Syndrome Secondary to Severe COVID-19 Pneumonia |
|
|
| Recruiting | N/A | 120 | Europe | | Fondation Hôpital Saint-Joseph | Dyspnea, COVID-19 | 06/24 | 12/24 | | |
| Not yet recruiting | N/A | 152 | Europe | early extubation of hypoxemic patients | Fondation Hôpital Saint-Joseph | Hypoxemia, Extubation, Postoperative Respiratory Complication | 10/26 | 01/27 | | |
NCT04494074: Fever Control Using External Cooling in Mechanically Ventilated Patients With Septic Shock |
|
|
| Recruiting | N/A | 820 | Europe | External Cooling | Centre Hospitalier Intercommunal Creteil | Septic Shock | 12/26 | 12/26 | | |
