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 23 Trials 
37 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Nichols, Elizabeth
NCT03785288: Vaginal Cuff Brachytherapy Fractionation Study

Recruiting
3
258
US
HDR vaginal brachytherapy
Kara Romano, MD
Endometrial Cancer
01/25
01/26
NCT01766297: Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

Recruiting
2
132
US
Proton Radiotherapy
Proton Collaborative Group
Breast Cancer, Breast Neoplasm, Breast Tumor, Cancer of the Breast
01/25
01/33
GCC 1876, NCT03562273: GammaPod Registry and Quality of Life Nomogram

Recruiting
N/A
160
US
Quality Of Life Sizing Nomogram, GammaPod Quality Of Life Sizing Nomogram
University of Maryland, Baltimore, University of Texas, Southwestern Medical Center at Dallas
Breast Cancer Female
12/26
12/27
NCT04234386: GammaPod Dose Escalation Radiation for Early Stage Breast Cancer

Recruiting
N/A
50
US
GammaPod Radiation
University of Maryland, Baltimore
Breast Cancer
12/26
12/28
PCG 001-09, NCT01255748: Registry Study for Radiation Therapy Outcomes

Recruiting
N/A
40000
US
Proton Therapy, Photon Therapy, SRS, Brachytherapy
Proton Collaborative Group
Neoplasms
06/39
 
Mishra, Mark
NRG-BN013, NCT06500455: Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Recruiting
3
269
US
Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Fractionated Stereotactic Radiation Therapy, Fractionated Stereotactic Radiotherapy, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Stereotactic Radiosurgery, SRS, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, Stereotactic Radiation Therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery
NRG Oncology, National Cancer Institute (NCI)
Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Breast Carcinoma, Metastatic Digestive System Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm, Metastatic Melanoma, Metastatic Renal Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8
06/28
06/33
METIS, NCT02831959: Pivotal, Open-label, Randomized Study of Radiosurgery with or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases from Non-small Cell Lung Cancer (NSCLC).

Completed
3
298
Europe, Canada, US, RoW
NovoTTF-200M device, Best Standard of Care
NovoCure GmbH
Brain Metastases from Non-small Cell Lung Cancer (NSCLC)
11/24
11/24
NRG-BN009, NCT04588246: Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Terminated
3
19
US
Memantine, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, Stereotactic Radiation Therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy
NRG Oncology, National Cancer Institute (NCI)
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Digestive System Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma, Metastatic Renal Cell Carcinoma, Prognostic Stage IV Breast Cancer AJCC v8, Recurrent Brain Neoplasm, Stage IV Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
08/24
08/24
NRG-CC009, NCT04804644: Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Recruiting
3
200
Canada, US
Memantine Hydrochloride, Ebixia, Namenda, Neurocognitive Assessment, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, Stereotactic Radiation Therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy
NRG Oncology, National Cancer Institute (NCI)
Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Recurrent Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
07/28
07/30
NRG-BN012, NCT05438212: Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases

Recruiting
3
236
Canada, US
Brain Surgery, Quality-of-Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery
NRG Oncology, National Cancer Institute (NCI)
Metastatic Malignant Neoplasm in the Brain
03/27
03/32
INDICATE, NCT04423211: Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

Recruiting
3
804
US
3-Dimensional Conformal Radiation Therapy, 3-dimensional radiation therapy, 3D Conformal, 3D CONFORMAL RADIATION THERAPY, 3D CRT, 3D radiotherapy, 3D-CRT, Conformal Therapy, Radiation Conformal Therapy, Radiation, 3D Conformal, Three dimensional external beam radiation therapy (procedure), Apalutamide, ARN 509, ARN-509, ARN509, Erleada, JNJ 56021927, JNJ-56021927, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, CT, CT Scan, tomography, Degarelix, FE200486, Firmagon, External Beam Radiation Therapy, Definitive Radiation Therapy, EBRT, External Beam Radiation, External Beam Radiotherapy, External Beam Radiotherapy (conventional), External Beam RT, external radiation, External Radiation Therapy, external-beam radiation, Radiation, External Beam, Teleradiotherapy, Teletherapy, Teletherapy Radiation, Fluciclovine F18, (18F)Fluciclovine, (18F)GE-148, 18F-Fluciclovine, [18F]FACBC, Anti-(18f)FABC, Anti-1-Amino-3-[18F]Fluorocyclobutane-1-Carboxylic Acid, Anti-[18F] FACBC, Axumin, Fluciclovine (18F), FLUCICLOVINE F-18, GE-148 (18F), GE-148 F-18, Goserelin Acetate, ZDX, Zoladex, Intensity-Modulated Proton Therapy, IMPT, Intensity-Modulated Radiation Therapy, IMRT, Intensity modulated radiation therapy (procedure), Intensity Modulated RT, Intensity-Modulated Radiotherapy, Radiation, Intensity-Modulated Radiotherapy, Leuprolide Acetate, A-43818, Abbott 43818, Abbott-43818, Carcinil, Depo-Eligard, Eligard, Enanton, Enantone, Enantone-Gyn, Ginecrin, LEUP, Leuplin, Leuprorelin Acetate, Lucrin, Lucrin Depot, Lupron, Lupron Depot, Lupron Depot-3 Month, Lupron Depot-4 Month, Lupron Depot-Ped, Lutrate, Procren, Procrin, Prostap, TAP-144, Trenantone, Uno-Enantone, Viadur, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Relugolix, N-(4-(1-((2,6-Difluorophenyl)methyl)-5-((dimethylamino)methyl)-1,2,3,4-tetrahydro-3-(6-methoxy-3-pyridazinyl)-2,4-dioxothieno(2,3-d)pyrimidin-6-yl)phenyl)-N'-methoxyurea, Orgovyx, TAK 385, TAK-385, Stereotactic Body Radiation Therapy, SABR, SBRT, Stereotactic Ablative Body Radiation Therapy, Triptorelin, 6-D-Tryptophan-LH-RH, 6-D-Tryptophanluteinizing Hormone-releasing Factor, AY-25650, CL-118,532, Detryptoreline, Volume Modulated Arc Therapy, VMAT, Volumetric Modulated Arc Therapy (procedure)
ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI)
Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Carcinoma, Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8
12/32
12/32
NRG-BN005, NCT03180502: Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

Active, not recruiting
2
148
US
IMRT (Intensity-Modulated Radiation Therapy), IMRT, Intensity Modulated RT, Intensity-Modulated Radiotherapy, Proton Beam Radiation Therapy, Temozolomide, CCRG-81045, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-, M & B 39831, M and B 39831, Methazolastone, RP-46161, SCH 52365, Temcad, Temodal, Temodar, Temomedac
NRG Oncology, National Cancer Institute (NCI)
1p/19q Co-deletion, Anaplastic Astrocytoma, Diffuse Astrocytoma, Glioma, IDH1 Gene Mutation, IDH2 Gene Mutation, Oligoastrocytoma, Oligodendroglioma, WHO Grade III Glioma
06/26
01/30
SAMURAI, NCT05327686: Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, Study

Recruiting
2
240
US
Avelumab, Bavencio, MSB-0010718C, MSB0010718C, Axitinib, AG-013736, AG013736, Inlyta, Cabozantinib, Ipilimumab, Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody, BMS-734016, Ipilimumab Biosimilar CS1002, MDX-010, MDX-CTLA4, Yervoy, Lenvatinib, E7080, ER-203492-00, Multi-Kinase Inhibitor E7080, Nivolumab, BMS-936558, CMAB819, MDX-1106, NIVO, Nivolumab Biosimilar CMAB819, ONO-4538, Opdivo, Pembrolizumab, Keytruda, Lambrolizumab, MK-3475, SCH 900475, Stereotactic Ablative Radiotherapy, SABER, SABR, SBRT, Stereotactic Ablative Radiation Therapy
NRG Oncology, National Cancer Institute (NCI)
Metastatic Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Unresectable Renal Cell Carcinoma
06/28
06/32
NCT04486755: Hypofractionated Accelerated Pelvic Nodal Radiotherapy (GCC 2048)

Recruiting
1
18
US
Hypofractionated Radiation Therapy
University of Maryland, Baltimore
Prostate Cancer, Prostate Adenocarcinoma
08/26
08/27
RADCOMP, NCT02603341: Pragmatic Randomized Trial of Proton Vs. Photon Therapy for Patients with Non-Metastatic Breast Cancer: a Radiotherapy Comparative Effectiveness () Consortium Trial

Active, not recruiting
N/A
1238
US
Photon, Proton
Abramson Cancer Center at Penn Medicine, Patient-Centered Outcomes Research Institute
Breast Cancer
08/28
11/36
GCCC 19140, NCT04181684: LITT Followed by Hypofractionated RT for Recurrent Gliomas

Recruiting
N/A
32
US
Procedure: LITT, Laser Interstitial thermal therapy, Hypo-Fractionated Radiation Therapy
University of Maryland, Baltimore, Keep Punching Foundation
Glioblastoma, Brain Tumor, Glioma, Neoplasms
12/25
12/26
NCT04699773: LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)

Recruiting
N/A
32
US
LITT, Laser Interstitial thermal therapy, Hypofractionated Radiation Therapy
University of Maryland, Baltimore, Keep Punching Foundation
Glioma, Glioblastoma, Brain Tumor
02/25
12/27
NCT03115333: DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

Recruiting
N/A
146
US
Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging, DSC-MRI, Dynamic Susceptibility Contrast-Enhanced MRI, DYNAMIC SUSCEPTIBILITY-CONTRAST MRI
ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI)
Gliosarcoma, Recurrent Glioblastoma
05/25
05/27
NCT05124912: REMASTer: REcurrent Brain Metastases After SRS Trial

Recruiting
N/A
261
US
Radiation Therapy, Steroid Therapy, Laser Interstitial Thermal Therapy
Monteris Medical
Brain Metastases, Radiation Necrosis, Recurrent Tumor, Recurrent Metastases
12/26
10/28
PCG 001-09, NCT01255748: Registry Study for Radiation Therapy Outcomes

Recruiting
N/A
40000
US
Proton Therapy, Photon Therapy, SRS, Brachytherapy
Proton Collaborative Group
Neoplasms
06/39
 
Qutab, Madiha
GCC 1876, NCT03562273: GammaPod Registry and Quality of Life Nomogram

Recruiting
N/A
160
US
Quality Of Life Sizing Nomogram, GammaPod Quality Of Life Sizing Nomogram
University of Maryland, Baltimore, University of Texas, Southwestern Medical Center at Dallas
Breast Cancer Female
12/26
12/27
NCT04234386: GammaPod Dose Escalation Radiation for Early Stage Breast Cancer

Recruiting
N/A
50
US
GammaPod Radiation
University of Maryland, Baltimore
Breast Cancer
12/26
12/28
Eggleston, Caitlin M
NCT03785288: Vaginal Cuff Brachytherapy Fractionation Study

Recruiting
3
258
US
HDR vaginal brachytherapy
Kara Romano, MD
Endometrial Cancer
01/25
01/26
KNIGHTS, NCT06212583: High-Risk Metachronous Oligometastatic Prostate Cancer Trial

Recruiting
2
88
US
niraparib/abiraterone acetate, Stereotactic ablative radiation therapy (SABR), Androgen deprivation therapy (ADT)
University of Maryland, Baltimore, Janssen Scientific Affairs, LLC
Prostate Cancer, Oligometastatic Disease
12/28
12/29
NCT01766297: Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

Recruiting
2
132
US
Proton Radiotherapy
Proton Collaborative Group
Breast Cancer, Breast Neoplasm, Breast Tumor, Cancer of the Breast
01/25
01/33
TERPs, NCT05223803: TERPS Trial for De Novo Oligometastic Prostate Cancer

Recruiting
2
122
US
Prostate radiation (XRT), Systemic Therapy, Stereotactic ablative radiation therapy (SABR)
University of Maryland, Baltimore
Prostate Cancer, Oligometastatic Disease
07/26
07/27
NCT06546969: Chemoimmunotherapy Combined with Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract Cancer

Recruiting
1
15
US
Gemcitabine, Cisplatin, Durvalumab, Spatially Fractionated RT, Deep Hyperthermia
University of Maryland, Baltimore
Biliary Tract Cancer, Cholangiocarcinoma
12/27
12/28
NEORADJUVANT, NCT06800339: A Phase I, Single-Arm, Single-Institution Study Evaluating Neoadjuvant Chemoimmunotherapy with Immunosensitizing Radiation for Borderline Resectable Non-Small Cell Lung Cancer

Not yet recruiting
1
18
US
Nivolumab, Chemotherapy, SBRT, Surgical Resection
University of Maryland, Baltimore
Non-Small Cell Lung Cancer
03/28
03/30
NCT06187103: Evaluation of Improved Onboard Patient Imaging

Recruiting
N/A
40
US
HyperSight Imaging
Varian, a Siemens Healthineers Company
Head and Neck Cancer, Breast Cancer, Upper Gastrointestinal Cancer, Lung Cancer, Pelvic Cancer
06/25
06/25
GCCC 19140, NCT04181684: LITT Followed by Hypofractionated RT for Recurrent Gliomas

Recruiting
N/A
32
US
Procedure: LITT, Laser Interstitial thermal therapy, Hypo-Fractionated Radiation Therapy
University of Maryland, Baltimore, Keep Punching Foundation
Glioblastoma, Brain Tumor, Glioma, Neoplasms
12/25
12/26
NCT04699773: LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)

Recruiting
N/A
32
US
LITT, Laser Interstitial thermal therapy, Hypofractionated Radiation Therapy
University of Maryland, Baltimore, Keep Punching Foundation
Glioma, Glioblastoma, Brain Tumor
02/25
12/27
PCG 001-09, NCT01255748: Registry Study for Radiation Therapy Outcomes

Recruiting
N/A
40000
US
Proton Therapy, Photon Therapy, SRS, Brachytherapy
Proton Collaborative Group
Neoplasms
06/39
 
Helie, Nicole
TERPs, NCT05223803: TERPS Trial for De Novo Oligometastic Prostate Cancer

Recruiting
2
122
US
Prostate radiation (XRT), Systemic Therapy, Stereotactic ablative radiation therapy (SABR)
University of Maryland, Baltimore
Prostate Cancer, Oligometastatic Disease
07/26
07/27
Kitzmiller, Kelly
SAVER, NCT04609280: Selective Avoidance of Nodal VolumEs at Minimal Risk (GCC 20110)

Active, not recruiting
2
52
US
Intensity modulated radiotherapy (IMRT)/volumetric modulated arc therapy (VMAT) or Pencil beam proton therapy (PBPT)
University of Maryland, Baltimore
Head and Neck Cancer, Oropharynx Cancer, Oropharyngeal Squamous Cell Carcinoma
12/26
12/27
SAVAL, NCT06088381: Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels

Recruiting
2
61
US
Experimental Observation, Observation per Standard of Care, Adjuvant Treatment per Standard of Care, Circulating Tumor DNA test (ctDNA test)
University of Maryland, Baltimore
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Oropharynx Cancer, Oropharynx Squamous Cell Carcinoma, HPV Positive Oropharyngeal Squamous Cell Carcinoma
10/25
10/27
NCT05959395: Hyperthermia Treatment Added to Chemotherapy Standard of Care for Pancreatic Tumors

Recruiting
N/A
5
US
VectRx Thermal Therapy
NeoTherma Oncology, University of Maryland, Baltimore, Databean
Pancreatic Cancer
02/24
04/24
Straub, Ermiece
NCT04527900: The UPPROACH (Upfront Intensity Modulated Proton Beam Therapy) Approach

Recruiting
2
21
US
carboplatin and paclitaxel, pelvic IMPT (Intensity Modulated Proton Therapy)
University of Maryland, Baltimore
Endometrial Cancer
09/27
09/28

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