| Kotsakis, Athanasios |
JADE, NCT06256588: A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma |
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| Recruiting | 3 | 864 | Europe, Canada, Japan, US, RoW | Dostarlimab, Placebo | GlaxoSmithKline | Neoplasms, Head and Neck | 05/28 | 07/29 | | |
EMBER-3, NCT04975308 / 2021-000079-35: A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer |
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| Active, not recruiting | 3 | 866 | Europe, Japan, US, RoW | Imlunestrant, LY3484356, Exemestane, Fulvestrant, Abemaciclib, LY2835219 | Eli Lilly and Company, Eli Lilly and Company | Breast Neoplasms, Neoplasm Metastasis | 06/24 | 08/27 | | |
| Recruiting | 3 | 500 | Europe, Canada, Japan, US, RoW | NBTXR3, Functionalized hafnium oxide nanoparticles, Cetuximab, Erbitux, Radiation Therapy | Nanobiotix | Locally Advanced Head and Neck Squamous Cell Carcinoma, Aged | 06/26 | 06/27 | | |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer |
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| Recruiting | 3 | 6000 | Europe, Canada, Japan, US, RoW | Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane | Eli Lilly and Company | Breast Neoplasms | 10/27 | 03/32 | | |
| Recruiting | 2 | 340 | Europe, Japan, US, RoW | Pembrolizumab, Dostarlimab, GSK4057190, Belrestotug, EOS884448, GSK4428859A, Nelistotug, GSK6097608 | GlaxoSmithKline, iTeos Therapeutics | Lung Cancer, Non-Small Cell | 10/25 | 10/28 | | |
| Recruiting | N/A | 675 | Europe | Implantable Cardioverter Defibrillator (ICD) insertion | University of Athens | Sudden Cardiac Death Due to Cardiac Arrhythmia, Dilated Cardiomyopathy | 05/25 | 05/25 | | |
NCT05496491: Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial |
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| Recruiting | N/A | 84 | Europe | Neoadjuvant Chemoradiotherapy, nCRT, Adjuvant Chemotherapy, AC, Consolidation Chemotherapy, CC | Larissa University Hospital | Rectal Neoplasms | 08/26 | 08/26 | | |
| Dalekos, George |
| Recruiting | 3 | 330 | Europe | Clarithromycin 500mg, A β-lactam/β-lactamase inhibitor or a 3rd generation cephalosporin or a fluoroquinolone, Tablets | Hellenic Institute for the Study of Sepsis | Community-acquired Pneumonia | 11/25 | 01/26 | | |
| Recruiting | 2/3 | 182 | Europe | Placebo, Anakinra 149 MG/ML Prefilled Syringe [Kineret] | Hellenic Institute for the Study of Sepsis | Post-Acute COVID-19 Syndrome, Post-Acute COVID-19, Long COVID | 08/25 | 08/25 | | |
| Active, not recruiting | 2 | 280 | Europe | Anakinra or rhIFNγ, Imukin, Kineret, Placebo | Hellenic Institute for the Study of Sepsis | Sepsis | 01/25 | 04/25 | | |
| Completed | 2 | 44 | Europe | Bezlotoxumab, Standard-of-care treatment according to local guidelines or to the decision of the attending physicians., Normal saline 0.9% or 5% dextrose water, Standard-of-care treatment according to local guidelines or to the decision of the attending physicians | Hellenic Institute for the Study of Sepsis | Clostridioides Difficile Infection, Stool Microbiome, Organ Dysfunction Syndrome, Clostridioides Difficile Infection Recurrence, Mortality | 06/23 | 06/23 | | |
| Arnaoutoglou, Eleni |
| Recruiting | N/A | 288 | Europe | Preoperative HbA1c | University of Thessaly, University Hospital, Ioannina, Larissa University Hospital | Neurocognitive Disorders, HbA1c | 09/21 | 11/21 | | |
| Recruiting | N/A | 288 | Europe | NLR, PLR | University of Thessaly, University Hospital, Ioannina, Larissa University Hospital | Neurocognitive Disorders, Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio | 12/21 | 12/21 | | |
NCT04736303: The Impact of the Implementation of BIS on the Incidence of Postoperative Delirium |
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| Recruiting | N/A | 1400 | Europe | BIS | University of Thessaly | Postoperative Delirium | 12/22 | 04/23 | | |
NCT06614478: Frailty, Hip Fractures and Inflammatory Biomarkers |
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| Recruiting | N/A | 200 | Europe | | University of Thessaly | Frailty, Hip Fracture, Inflammatory Biomarkers | 12/25 | 01/26 | | |
NCT04380129: Music Therapy Model "The Bonny Method of Guided Imagery and Music" on Patients With Rheumatoid Arthritis |
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| Not yet recruiting | N/A | 74 | Europe | Music therapy-conversation sessions, GIM Bonny Method, Discussion sessions | University of Thessaly | Rheumatoid Arthritis, Quality of Life, Chronic Pain | 09/23 | 12/23 | | |
| Not yet recruiting | N/A | 200 | Europe | Dexmedetomidine, Remifentanil | University of Thessaly | Functional Endoscopic Sinus Surgery | 10/23 | 12/23 | | |
G-GFI, NCT05091645: Translation and Cultural Adaptation of the Groningen Frailty Indicator (GFI) in Patients With Hip Fracture |
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| Recruiting | N/A | 89 | Europe | GFI | University of Thessaly | Frailty Syndrome, Hip Fractures | 06/24 | 07/24 | | |
| Completed | N/A | 55 | Europe | VIOSync-SPI | Aisthesis Medical P.C., Larissa University Hospital, Technical University of Crete | Sepsis, Abdominal Sepsis, Infections, Clinical Deterioration, Hemodynamic Instability | 06/24 | 06/24 | | |
| Not yet recruiting | N/A | 200 | Europe | Dexmedetomidine | University of Thessaly | Acute Kidney Injury, Dexmedetomidine, Endovascular Aortic Repair | 11/23 | 02/24 | | |
| Recruiting | N/A | 30 | Europe | ERAS | University of Thessaly | ERAS, Craniotomy | 05/24 | 07/24 | | |
CoFA-TAAA, NCT06432387: Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair |
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| Not yet recruiting | N/A | 58 | Europe | Patients undergoing complex thoraco-abdominal aortic aneurysm repair | University of Thessaly | Thoraco-abdominal Aortic Aneurysm Repair, Coagulation Factors Alterations, Platelet Activation | 12/25 | 01/26 | | |
| Recruiting | N/A | 64 | Europe | | University of Thessaly | Venous Thromboembolism, Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma | 09/24 | 10/24 | | |
NCT04108546: Massage and Electroacupuncture in Chronic Lumbar Pain |
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| Recruiting | N/A | 110 | Europe | Electroacupuncture device, Epidural analgesia | University of Thessaly | Back Pain, Lumbar, Anesthesia, Local, Epidural, Electroacupuncture, Massage | 10/24 | 12/24 | | |
NCT05518643: Compliance With ERAS Protocol in Pancreatic Surgery, Stress Response and Outcomes |
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| Recruiting | N/A | 120 | Europe | ERAS protocol | University of Thessaly, IASO Thessalias, Larissa University Hospital | ERAS, Pancreas Cancer, Pancreas; Fistula, Delayed Gastric Emptying, Surgery-Complications, Pancreatic Hemorrhage, PROMs | 08/25 | 08/26 | | |
| Daniil, Zoe |
NCT05032066: A Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects With Idiopathic Pulmonary Fibrosis |
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| Active, not recruiting | 2 | 153 | Europe, Canada, Japan, US, RoW | HZN-825, Placebo | Amgen | Idiopathic Pulmonary Fibrosis | 07/24 | 07/25 | | |
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| Vajter, Jaromir |
NCT06054997: Anaesthesiologic Considerations for Intraoperative ECMO Anticoagulation During Lung Transplantation |
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| Completed | N/A | 141 | RoW | | University Hospital, Motol | Lung Transplantation | 12/22 | 08/23 | | |
| Recruiting | N/A | 20000 | Europe, RoW | VAP | European Clinical Research Alliance for Infectious Diseases (ECRAID), Centre Hospitalier Universitaire Dupuytren de Limoges (CHUL), Université de Genève (UNIGE), University Medical Center Utrecht (UMCU) | Ventilator Associated Pneumonia | 12/25 | 03/26 | | |
| Completed | N/A | 2165 | Europe, RoW | | UMC Utrecht, Universiteit Antwerpen, University Hospital, Geneva | Hospital-acquired Pneumonia, Ventilator Associated Pneumonia | 05/22 | 01/23 | | |
| Kotsakis, Athansios |
| Recruiting | N/A | 200 | Europe | Digital platform | Hellenic Cooperative Oncology Group, Stavros Niarchos Foundation, Care Across Ltd | Non-Small Cell Carcinoma of Lung, TNM Stage 4 | 09/24 | 03/25 | | |
| Oikonomou, Georgia |
| Recruiting | 2/3 | 344 | Europe, Canada, US, RoW | Etavopivat Tablets Low dose, FT-4202, Etavopivat Tablets High dose, Placebo Tablets, placebo, Etavopivat Tablets | Forma Therapeutics, Inc., Novo Nordisk A/S | Sickle Cell Disease | 03/26 | 04/27 | | |
| Christodoulou, Ioanna |
| Recruiting | 2/3 | 344 | Europe, Canada, US, RoW | Etavopivat Tablets Low dose, FT-4202, Etavopivat Tablets High dose, Placebo Tablets, placebo, Etavopivat Tablets | Forma Therapeutics, Inc., Novo Nordisk A/S | Sickle Cell Disease | 03/26 | 04/27 | | |
| Mercone, Katia |
| Recruiting | 2/3 | 344 | Europe, Canada, US, RoW | Etavopivat Tablets Low dose, FT-4202, Etavopivat Tablets High dose, Placebo Tablets, placebo, Etavopivat Tablets | Forma Therapeutics, Inc., Novo Nordisk A/S | Sickle Cell Disease | 03/26 | 04/27 | | |
