Axis Clinical Trials
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 14 Trials 
29 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Fernandez, Maria E
NCT03393975 / 2017-000858-18: A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)

Completed
3
52
Europe, Japan, US
TAK-755, rADAMTS13, SHP-655, recombinant ADAMTS13, BAX 930, Standard of care
Baxalta now part of Shire, Takeda Development Center Americas, Inc.
Thrombotic Thrombocytopenic Purpura (TTP)
12/23
05/24
LIMT-2, NCT05070364 / 2021-003665-35: Phase 3 Study to Evaluate the Efficacy and Safety of Peginterferon Lambda for 48 Weeks in Patients With Chronic HDV

Active, not recruiting
3
150
Europe, US, RoW
Peginterferon Lambda-1a, Lambda, Peginterferon Lambda, Pegylated Interferon Lambda
Eiger BioPharmaceuticals, Eiger BioPharmaceuticals, Inc.
Hepatitis Delta Virus
06/24
01/25
BRAVE-AA-PEDS, NCT05723198: A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

Recruiting
3
595
Europe, Canada, Japan, US, RoW
Baricitinib, LY3009104, Placebo
Eli Lilly and Company
Areata Alopecia, Alopecia, Hypotrichosis, Hair Diseases, Skin Diseases, Pathological Conditions, Anatomical
09/27
08/29
REITAB-2, NCT05204563: Imipenem/Cilastatin-XNW4107 Versus Imipenem/Cilastatin/Relebactam for Treatment of Participants with Bacterial Pneumonia (XNW4107-302, )

Completed
3
450
Europe, US, RoW
Combination of Imipenem/Cilastatin and XNW4107, Imipenem/Cilastatin/Relebactam, Recarbrio
Evopoint Biosciences Inc.
Hospital Acquired Bacterial Pneumonia or Ventilator-Associated Bacterial Pneumonia
09/24
09/24
MOUNTAINEER-03, NCT05253651 / 2021-002672-40: A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

Recruiting
3
400
Europe, Canada, Japan, US, RoW
tucatinib, TUKYSA, ONT-380, ARRY-380, PF-07265792, trastuzumab, Herceptin, bevacizumab, Avastin, cetuximab, Erbitux, oxaliplatin, leucovorin, levoleucovorin, fluorouracil
Seagen, a wholly owned subsidiary of Pfizer, Merck Sharp & Dohme LLC
Colorectal Neoplasms
04/26
07/29
NCT04683003: A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura

Recruiting
3
77
Europe, Japan, US, RoW
TAK-755, rADAMTS13; recombinant ADAMTS13; SHP-655; BAX 930
Takeda, Takeda Development Center Americas, Inc., Shire
Thrombotic Thrombocytopenic Purpura (TTP)
03/27
03/27
Phenomenal, NCT03328884 / 2016-002689-30: Evaluation of the Efficacy and Safety of Nal-IRI for Progressing Brain Metastases in Breast Cancer Patients

Completed
2
55
Europe
Irinotecan (CPT-11) liposome, nal-IRI
MedSIR
Breast Cancer Metastatic
08/18
04/25
CAMPFIRE, NCT05999994: A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

Recruiting
2
105
Europe, Japan, US, RoW
Ramucirumab, LY3009806, Cyclophosphamide, Vinorelbine, Gemcitabine, LY188011, Docetaxel, Abemaciclib, LY2835219, Irinotecan, Temozolomide
Eli Lilly and Company
Neoplasms, Child, Adolescent
05/27
05/27
NCT05440786 / 2021-004734-11: CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma

Active, not recruiting
2
45
Europe, Japan, US, RoW
Abemaciclib, LY2835219, Irinotecan, Temozolomide
Eli Lilly and Company
Sarcoma, Ewing, Neoplasm Metastasis
01/25
09/28
NCT05606003: Using a Community-level Just-in-Time Adaptive Intervention to Address COVID-19 Testing Disparities

Active, not recruiting
N/A
1280
US
Multi-Level Multi-Component Intervention (MLI), Community Just-In-Time Adaptive Intervention (Community JITAI)
The University of Texas Health Science Center, Houston, National Center for Advancing Translational Sciences (NCATS)
COVID-19
06/22
12/22
NCT04438265: Quadratus Lumborum Type 2 as Chronic Hip Pain Treatment

Completed
N/A
200
Europe
levobupivacaine, chirocane, ultrasound device
Hospital Medina del Campo, Hospital Universitaio Getafe, Hospital Rio Hortega
Hip Arthropathy, Chronic Hip Pain, Ultrasound Therapy; Complications
09/22
06/24
NCT05606016: Examining How a Facilitated Self-Sampling Intervention and Testing Navigation Intervention Influences COVID-19 Testing

Not yet recruiting
N/A
1280
US
Facilitated Self-Sampling Intervention (FSSI), Testing Navigation Intervention (TNI)., Control
The University of Texas Health Science Center, Houston, National Center for Advancing Translational Sciences (NCATS)
COVID-19
01/23
04/23
NCT04431388: Serratus-intercostal Plane Block Versus Quadratus Lumborum Block in Nephrectomy: Randomized Study

Completed
N/A
126
Europe
ultrasound device, device, Levobupivacaine, drug
Hospital Medina del Campo
Kidney Injury
06/23
12/23
NCT05524480: Accelerating the Implementation of a Breast and Cervical Cancer Screening and HPV Vaccination Intervention

Enrolling by invitation
N/A
2000
US
Salud en Mis Manos - Dissemination and Implementation Assistance, SEMM-DIA, Salud en Mis Manos- Usual Implementation Practice, SEMM
The University of Texas Health Science Center, Houston, Centers for Disease Control and Prevention
Cancer Prevention
06/25
09/25
Stacey, Helen
NCT06389487: A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus (RSV) Given to Adults 18 to 49 Years of Age at Increased Risk for Respiratory Syncytial Virus Disease, Compared to Older Adults 60 Years of Age and Above

Completed
3
1459
Europe, Canada, Japan, US, RoW
RSVPreF3 OA investigational vaccine
GlaxoSmithKline
Respiratory Syncytial Virus Infections
07/24
03/25
TRIUMPH-5, NCT06662383: A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity

Recruiting
3
800
Europe, US, RoW
Retatrutide, LY3437943, Tirzepatide, LY3298176
Eli Lilly and Company
Obesity
04/27
04/27
TRIUMPH-2, NCT05929079: A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight

Active, not recruiting
3
1000
Europe, US, RoW
Retatrutide, LY3437943, Placebo
Eli Lilly and Company
Type 2 Diabetes, Obesity, Overweight, Obstructive Sleep Apnea
05/26
05/26
Hazan, Lydie
NCT04636229: Efficacy of Amniotic Suspension Allograft in Patients with Osteoarthritis of the Knee

Active, not recruiting
3
474
US
Amniotic Suspension Allograft, Placebo
Organogenesis, Premier Research Group plc
Knee Osteoarthritis
07/23
06/25
Lopez, Carlos J
NCT05947084: Comparison of Growth and Tolerance of Healthy Term Infants Fed Iron-Fortified Infant Formulas

Active, not recruiting
3
440
US
Infant Formula
Aussie Bubs, Inc.
Infant Development
04/25
04/25
NCT06693895: A Study on the Safety of an Investigational Chickenpox Vaccine, When Given to Healthy Children, 12 to 15 Months of Age

Recruiting
3
750
US
Investigational varicella vaccine, Marketed varicella vaccine, Measles, mumps, and rubella vaccine, Hepatitis A vaccine, PCV (pneumococcal conjugate vaccine) 13, PCV 20, Vaxneuvance
GlaxoSmithKline
Chickenpox
07/26
11/26
NCT05412030: A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy Infants

Active, not recruiting
2
472
US
AFX3772, Prevnar 13, PCV13, Prevnar 20, PCV20
GlaxoSmithKline, Affinivax, Inc.
Pneumonia, Bacterial, Pneumococcal Infections, Pneumonia, Pneumococcal
07/26
07/26
SVFCOVID-19, NCT06304623: SVF for Treating Pulmonary Fibrosis Post COVID-19

Completed
1
40
RoW
Autologous adipose-derived SVF IV administration
Michael H Carstens, Ministerio de Salud de Nicaragua, Wake Forest University, National Autonomous University of Nicaragua
Pulmonary Fibrosis
03/24
03/24
DARC-VADOC, NCT04800783: Diagnostic Accuracy of Aerodigestive Ultrasound for Predicting Swallowing Disorders

Completed
N/A
124
Europe
Swallowing ultrasound
Hopital Forcilles
Deglutition Disorders
04/23
04/23
CAPTAIN, NCT05027477: A Comparison of TULSA Procedure vs. Radical Prostatectomy in Participants With Localized Prostate Cancer

Recruiting
N/A
201
Europe, Canada, US
Radical Prostatectomy, TULSA Procedure, TULSA-PRO
Profound Medical Inc.
Prostate Cancer, Prostate Adenocarcinoma
03/25
03/35
R-2D-2, NCT06387004: Radiation-Related Dysphagia Development Prediction Using a Two-Step Ultrasonographic Model

Recruiting
N/A
112
Europe
Hopital Forcilles
Swallowing Disorders
02/26
02/26
NCT06217328: RESTORE: An RCT to Evaluate the Efficacy of the Revi System

Recruiting
N/A
150
US
Revi System Treatment, Revi System - Delayed Activation
BlueWind Medical
Urinary Urge Incontinence
05/26
05/27
SHUBACA, NCT06630013: A New Ultrasound Score for Swallowing Disorders Diagnosis in Difficult-to-wean Tracheostomised Patients

Recruiting
N/A
114
Europe
Hopital Forcilles
Deglutition Disorders
02/26
04/26
NCT05031507: Study of Skeletal Disorders

Recruiting
N/A
100
US
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Skeletal Disorders
12/25
07/26
Gutierrez, Elizabeth
NCT05139121: Study of the Safety and Efficacy of MR-100A-01 in Approximately 1200 Healthy Women for up to 13 Cycles

Completed
3
1319
Canada, US
MR-100A-01, Transdermal contraceptive delivery system
Mylan Technologies Inc., Mylan Inc.
Contraception
01/25
01/25
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Fernandez, Maria E
NCT03393975 / 2017-000858-18: A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)

Completed
3
52
Europe, Japan, US
TAK-755, rADAMTS13, SHP-655, recombinant ADAMTS13, BAX 930, Standard of care
Baxalta now part of Shire, Takeda Development Center Americas, Inc.
Thrombotic Thrombocytopenic Purpura (TTP)
12/23
05/24
LIMT-2, NCT05070364 / 2021-003665-35: Phase 3 Study to Evaluate the Efficacy and Safety of Peginterferon Lambda for 48 Weeks in Patients With Chronic HDV

Active, not recruiting
3
150
Europe, US, RoW
Peginterferon Lambda-1a, Lambda, Peginterferon Lambda, Pegylated Interferon Lambda
Eiger BioPharmaceuticals, Eiger BioPharmaceuticals, Inc.
Hepatitis Delta Virus
06/24
01/25
BRAVE-AA-PEDS, NCT05723198: A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

Recruiting
3
595
Europe, Canada, Japan, US, RoW
Baricitinib, LY3009104, Placebo
Eli Lilly and Company
Areata Alopecia, Alopecia, Hypotrichosis, Hair Diseases, Skin Diseases, Pathological Conditions, Anatomical
09/27
08/29
REITAB-2, NCT05204563: Imipenem/Cilastatin-XNW4107 Versus Imipenem/Cilastatin/Relebactam for Treatment of Participants with Bacterial Pneumonia (XNW4107-302, )

Completed
3
450
Europe, US, RoW
Combination of Imipenem/Cilastatin and XNW4107, Imipenem/Cilastatin/Relebactam, Recarbrio
Evopoint Biosciences Inc.
Hospital Acquired Bacterial Pneumonia or Ventilator-Associated Bacterial Pneumonia
09/24
09/24
MOUNTAINEER-03, NCT05253651 / 2021-002672-40: A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

Recruiting
3
400
Europe, Canada, Japan, US, RoW
tucatinib, TUKYSA, ONT-380, ARRY-380, PF-07265792, trastuzumab, Herceptin, bevacizumab, Avastin, cetuximab, Erbitux, oxaliplatin, leucovorin, levoleucovorin, fluorouracil
Seagen, a wholly owned subsidiary of Pfizer, Merck Sharp & Dohme LLC
Colorectal Neoplasms
04/26
07/29
NCT04683003: A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura

Recruiting
3
77
Europe, Japan, US, RoW
TAK-755, rADAMTS13; recombinant ADAMTS13; SHP-655; BAX 930
Takeda, Takeda Development Center Americas, Inc., Shire
Thrombotic Thrombocytopenic Purpura (TTP)
03/27
03/27
Phenomenal, NCT03328884 / 2016-002689-30: Evaluation of the Efficacy and Safety of Nal-IRI for Progressing Brain Metastases in Breast Cancer Patients

Completed
2
55
Europe
Irinotecan (CPT-11) liposome, nal-IRI
MedSIR
Breast Cancer Metastatic
08/18
04/25
CAMPFIRE, NCT05999994: A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

Recruiting
2
105
Europe, Japan, US, RoW
Ramucirumab, LY3009806, Cyclophosphamide, Vinorelbine, Gemcitabine, LY188011, Docetaxel, Abemaciclib, LY2835219, Irinotecan, Temozolomide
Eli Lilly and Company
Neoplasms, Child, Adolescent
05/27
05/27
NCT05440786 / 2021-004734-11: CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma

Active, not recruiting
2
45
Europe, Japan, US, RoW
Abemaciclib, LY2835219, Irinotecan, Temozolomide
Eli Lilly and Company
Sarcoma, Ewing, Neoplasm Metastasis
01/25
09/28
NCT05606003: Using a Community-level Just-in-Time Adaptive Intervention to Address COVID-19 Testing Disparities

Active, not recruiting
N/A
1280
US
Multi-Level Multi-Component Intervention (MLI), Community Just-In-Time Adaptive Intervention (Community JITAI)
The University of Texas Health Science Center, Houston, National Center for Advancing Translational Sciences (NCATS)
COVID-19
06/22
12/22
NCT04438265: Quadratus Lumborum Type 2 as Chronic Hip Pain Treatment

Completed
N/A
200
Europe
levobupivacaine, chirocane, ultrasound device
Hospital Medina del Campo, Hospital Universitaio Getafe, Hospital Rio Hortega
Hip Arthropathy, Chronic Hip Pain, Ultrasound Therapy; Complications
09/22
06/24
NCT05606016: Examining How a Facilitated Self-Sampling Intervention and Testing Navigation Intervention Influences COVID-19 Testing

Not yet recruiting
N/A
1280
US
Facilitated Self-Sampling Intervention (FSSI), Testing Navigation Intervention (TNI)., Control
The University of Texas Health Science Center, Houston, National Center for Advancing Translational Sciences (NCATS)
COVID-19
01/23
04/23
NCT04431388: Serratus-intercostal Plane Block Versus Quadratus Lumborum Block in Nephrectomy: Randomized Study

Completed
N/A
126
Europe
ultrasound device, device, Levobupivacaine, drug
Hospital Medina del Campo
Kidney Injury
06/23
12/23
NCT05524480: Accelerating the Implementation of a Breast and Cervical Cancer Screening and HPV Vaccination Intervention

Enrolling by invitation
N/A
2000
US
Salud en Mis Manos - Dissemination and Implementation Assistance, SEMM-DIA, Salud en Mis Manos- Usual Implementation Practice, SEMM
The University of Texas Health Science Center, Houston, Centers for Disease Control and Prevention
Cancer Prevention
06/25
09/25
Stacey, Helen
NCT06389487: A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus (RSV) Given to Adults 18 to 49 Years of Age at Increased Risk for Respiratory Syncytial Virus Disease, Compared to Older Adults 60 Years of Age and Above

Completed
3
1459
Europe, Canada, Japan, US, RoW
RSVPreF3 OA investigational vaccine
GlaxoSmithKline
Respiratory Syncytial Virus Infections
07/24
03/25
TRIUMPH-5, NCT06662383: A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity

Recruiting
3
800
Europe, US, RoW
Retatrutide, LY3437943, Tirzepatide, LY3298176
Eli Lilly and Company
Obesity
04/27
04/27
TRIUMPH-2, NCT05929079: A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight

Active, not recruiting
3
1000
Europe, US, RoW
Retatrutide, LY3437943, Placebo
Eli Lilly and Company
Type 2 Diabetes, Obesity, Overweight, Obstructive Sleep Apnea
05/26
05/26
Hazan, Lydie
NCT04636229: Efficacy of Amniotic Suspension Allograft in Patients with Osteoarthritis of the Knee

Active, not recruiting
3
474
US
Amniotic Suspension Allograft, Placebo
Organogenesis, Premier Research Group plc
Knee Osteoarthritis
07/23
06/25
Lopez, Carlos J
NCT05947084: Comparison of Growth and Tolerance of Healthy Term Infants Fed Iron-Fortified Infant Formulas

Active, not recruiting
3
440
US
Infant Formula
Aussie Bubs, Inc.
Infant Development
04/25
04/25
NCT06693895: A Study on the Safety of an Investigational Chickenpox Vaccine, When Given to Healthy Children, 12 to 15 Months of Age

Recruiting
3
750
US
Investigational varicella vaccine, Marketed varicella vaccine, Measles, mumps, and rubella vaccine, Hepatitis A vaccine, PCV (pneumococcal conjugate vaccine) 13, PCV 20, Vaxneuvance
GlaxoSmithKline
Chickenpox
07/26
11/26
NCT05412030: A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy Infants

Active, not recruiting
2
472
US
AFX3772, Prevnar 13, PCV13, Prevnar 20, PCV20
GlaxoSmithKline, Affinivax, Inc.
Pneumonia, Bacterial, Pneumococcal Infections, Pneumonia, Pneumococcal
07/26
07/26
SVFCOVID-19, NCT06304623: SVF for Treating Pulmonary Fibrosis Post COVID-19

Completed
1
40
RoW
Autologous adipose-derived SVF IV administration
Michael H Carstens, Ministerio de Salud de Nicaragua, Wake Forest University, National Autonomous University of Nicaragua
Pulmonary Fibrosis
03/24
03/24
DARC-VADOC, NCT04800783: Diagnostic Accuracy of Aerodigestive Ultrasound for Predicting Swallowing Disorders

Completed
N/A
124
Europe
Swallowing ultrasound
Hopital Forcilles
Deglutition Disorders
04/23
04/23
CAPTAIN, NCT05027477: A Comparison of TULSA Procedure vs. Radical Prostatectomy in Participants With Localized Prostate Cancer

Recruiting
N/A
201
Europe, Canada, US
Radical Prostatectomy, TULSA Procedure, TULSA-PRO
Profound Medical Inc.
Prostate Cancer, Prostate Adenocarcinoma
03/25
03/35
R-2D-2, NCT06387004: Radiation-Related Dysphagia Development Prediction Using a Two-Step Ultrasonographic Model

Recruiting
N/A
112
Europe
Hopital Forcilles
Swallowing Disorders
02/26
02/26
NCT06217328: RESTORE: An RCT to Evaluate the Efficacy of the Revi System

Recruiting
N/A
150
US
Revi System Treatment, Revi System - Delayed Activation
BlueWind Medical
Urinary Urge Incontinence
05/26
05/27
SHUBACA, NCT06630013: A New Ultrasound Score for Swallowing Disorders Diagnosis in Difficult-to-wean Tracheostomised Patients

Recruiting
N/A
114
Europe
Hopital Forcilles
Deglutition Disorders
02/26
04/26
NCT05031507: Study of Skeletal Disorders

Recruiting
N/A
100
US
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Skeletal Disorders
12/25
07/26
Gutierrez, Elizabeth
NCT05139121: Study of the Safety and Efficacy of MR-100A-01 in Approximately 1200 Healthy Women for up to 13 Cycles

Completed
3
1319
Canada, US
MR-100A-01, Transdermal contraceptive delivery system
Mylan Technologies Inc., Mylan Inc.
Contraception
01/25
01/25

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