| Krishnan, Jerry A |
| Recruiting | 4 | 1250 | US | Roflumilast, Daliresp, Azithromycin, Zithromax | Johns Hopkins University, Patient-Centered Outcomes Research Institute, University of Illinois at Chicago | Chronic Obstructive Pulmonary Disease Severe, Chronic Bronchitis | 03/26 | 05/26 | | |
NCT04129931: PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study |
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| Active, not recruiting | 2 | 395 | US | MCT, Breathe Better Diet (BBD), Clazakizumab, Anti-interleukin 6 monoclonal antibody, Anti-IL-6 mAb, BMS-945429, ALD518, Broncho-Vaxom, OM-85 BV VEGETAL, Imatinib Mesylate, Gleevec, Zoleta, Glivec, Ziatir, Cavosonstat, N91115, Placebo | University of North Carolina, Chapel Hill, National Heart, Lung, and Blood Institute (NHLBI) | Asthma | 12/24 | 12/24 | | |
| Active, not recruiting | N/A | 64 | US | PACE2 Intervention | University of Illinois at Chicago, National Heart, Lung, and Blood Institute (NHLBI) | Chronic Obstructive Pulmonary Disease | 01/22 | 05/22 | | |
NCT04543461: American Lung Association (ALA) Lung Health Cohort |
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| Recruiting | N/A | 4000 | US | | Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI), American Lung Association, Stanford University | Lung Diseases | 09/26 | 09/26 | | |
| Active, not recruiting | N/A | 2981 | US | | University of North Carolina, Chapel Hill, National Heart, Lung, and Blood Institute (NHLBI), COPD Foundation, Columbia University, Johns Hopkins University, National Jewish Health, Temple University, University of Alabama at Birmingham, University of California, Los Angeles, University of California, San Francisco, University of Illinois at Chicago, University of Iowa, University of Michigan, University of Utah, Wake Forest University | COPD, Chronic Obstructive Pulmonary Disease, Chronic Bronchitis, Emphysema | 12/30 | 12/30 | | |
| Recruiting | N/A | 1000 | US | | Weill Medical College of Cornell University, National Heart, Lung, and Blood Institute (NHLBI), University of North Carolina, Chapel Hill, Columbia University, Johns Hopkins University, National Jewish Health, University of Alabama at Birmingham, University of California, Los Angeles, University of Illinois at Chicago, University of Iowa, University of Michigan, University of Utah, Wake Forest University Health Sciences, Temple University, University of California, San Francisco, COPD Foundation, Mayo Clinic | COPD, Early-Onset | 01/25 | 04/25 | | |
NCT05172024: Understanding the Long-term Impact of COVID-19 in Adults (RECOVER) |
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| Active, not recruiting | N/A | 15178 | US | | NYU Langone Health, National Heart, Lung, and Blood Institute (NHLBI) | SARS-CoV2 Infection | 04/25 | 05/25 | | |
| Alaraj, Ali |
| Recruiting | 3 | 700 | US | Apixaban, Eliquis, Aspirin | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Intracerebral Hemorrhage, Atrial Fibrillation | 04/27 | 04/27 | | |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Recruiting | N/A | 520 | US | Conventional Surgery, Middle Meningeal Artery Embolization (MMAE) | The University of Texas Medical Branch, Galveston, National Institute of Neurological Disorders and Stroke (NINDS) | Chronic Subdural Hematoma | 09/28 | 09/28 | | |
CAPTIVA-MRI, NCT05907629: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging |
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| Recruiting | N/A | 300 | US | MRI | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Stroke, Intracranial Atherosclerotic Stenosis (ICAS) | 03/29 | 03/29 | | |
| Recruiting | N/A | 40000 | Europe, Canada, Japan, US, RoW | Stroke/Thrombectomy/Aneurysm-specific surgical procedures | Medical University of South Carolina | Stroke, Thromboses, Intracranial, Aneurysm, Brain | 01/55 | 01/55 | | |
| Amin-Hanjani, Sepideh |
| Recruiting | 3 | 700 | US | Apixaban, Eliquis, Aspirin | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Intracerebral Hemorrhage, Atrial Fibrillation | 04/27 | 04/27 | | |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
CAPTIVA-MRI, NCT05907629: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging |
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| Recruiting | N/A | 300 | US | MRI | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Stroke, Intracranial Atherosclerotic Stenosis (ICAS) | 03/29 | 03/29 | | |
VERiTASII, NCT03729817: REstoring Flow by REvascularization with Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis |
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| Not yet recruiting | N/A | 159 | US | Submaximal balloon angioplasty | Case Western Reserve University, National Institute of Neurological Disorders and Stroke (NINDS) | Intracranial Atherosclerotic Disease, Stroke, Angioplasty, Balloon, Hemodynamics, Device Safety | 10/29 | 10/30 | | |
| Khanna, Anna |
CREST-H, NCT03121209: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics |
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| Active, not recruiting | 3 | 385 | Canada, US | Revascularization, Intensive Medical Management (IMM) alone | Columbia University, National Institute of Neurological Disorders and Stroke (NINDS), Mayo Clinic, University of Alabama at Birmingham, University of Maryland, University of California, Los Angeles | Internal Carotid Artery Stenosis, Cognitive Impairment | 01/27 | 07/27 | | |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Recruiting | 3 | 860 | Europe, Canada, Japan, US | Recombinant Activated Factor VII (rFVIIa), NovoSeven, NiaStase, Placebo | Joseph Broderick, MD, Novo Nordisk A/S, National Institute of Neurological Disorders and Stroke (NINDS) | Intracerebral Hemorrhage | 01/28 | 01/28 | | |
CREST-2, NCT02089217: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial |
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| Active, not recruiting | N/A | 2486 | Europe, Canada, US, RoW | Carotid endarterectomy (CEA), Carotid Stenting (CAS), Intensive Medical Management - no CEA, Intensive Medical Management - no CAS | Thomas G. Brott, M.D., National Institute of Neurological Disorders and Stroke (NINDS) | Carotid Stenosis | 02/26 | 02/26 | | |
| Recruiting | N/A | 3062 | US | CPAP | University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati | Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial | 11/26 | 11/26 | | |
| Williams, Mark V |
NCT05476276: EPPIC-Net: Platform Protocol to Assess Treatments for Painful Diabetic Peripheral Neuropathy |
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| Recruiting | 2 | 122 | US | ISA specific | James P. Rathmell, MD, New York University, Icahn School of Medicine at Mount Sinai, National Institute of Neurological Disorders and Stroke (NINDS) | Painful Diabetic Neuropathy | 01/25 | 01/25 | | |
| Recruiting | 2 | 122 | US | NRD135SE.1, NRD135s.E1, a small chemical entity for treatment of neuropathic pain, Placebo | James P. Rathmell, MD, New York University, National Institute of Neurological Disorders and Stroke (NINDS), Icahn School of Medicine at Mount Sinai | Painful Diabetic Neuropathy | 01/25 | 01/25 | | |
| Recruiting | N/A | 300 | Europe | Blood sample collection, Bone marrow aspirate | University of Manchester, The Christie NHS Foundation Trust | Haematopoietic Stem Cell Transplantation | 08/25 | 08/28 | | |
Destiny, NCT05109260: D-dimer. Investigating D-dimer Levels Using Point-of-Care (POC) Testing at Primary Care. |
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| Recruiting | N/A | 244 | Europe | Point-of-Care Immunoassay device | University of South Wales | Deep Vein Thrombosis | 09/22 | 03/23 | | |
| Hanel, Ricardo A |
NECC, NCT04852783: US IDE Study of the Contour NEurovasCular System™ for IntraCranial Aneurysm Repair |
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| Active, not recruiting | 4 | 250 | US | Contour Neurovascular System | Cerus Endovascular, Inc. | Aneurysm, Intracranial | 12/25 | 12/29 | | |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Recruiting | 2/3 | 200 | Europe, Canada, US | Immediate mechanical thrombectomy(iMT) using EmboTrap Revascularization Device, EmboTrap III, Initial medical management (iMM) | Emory University, University of Calgary, University of Cincinnati, Heidelberg University, Children's Hospital Medical Center, Cincinnati | Cerebral Ischemia | 12/24 | 12/24 | | |
| Recruiting | 1 | 24 | US | PP-007 (Two doses administered 24±6 hours apart) + SOC (IVT or MT or IVT+MT), Sanguinate | Prolong Pharmaceuticals | Acute Ischemic Stroke | 12/24 | 02/25 | | |
NCT04518670: Success in Comaneci-assist Coils Embolization Surveillance Study (SUCCESS) |
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| Completed | N/A | 90 | US | Comaneci Embolization Assist Device | Rapid Medical | Intracranial Aneurysm | 05/24 | 07/24 | | |
| Completed | N/A | 121 | Canada, US, RoW | AneurysmFlow | Philips Clinical & Medical Affairs Global | Intracranial Aneurysm | 11/23 | 11/23 | | |
STEM, NCT04410146: The SQUID Trial for the Embolization of the Middle Meningeal Artery for Treatment of Chronic Subdural Hematoma |
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| Completed | N/A | 310 | Europe, US | SQUID Embolization, SQUID Embolization and Surgical Evacuation, Surgical Evacuation, Other: Medical Management | Balt USA, Balt Extrusion, Embo-Flüssigkeiten A.G., AXIOM Real Time Metrics | Subdural Hematoma, Chronic | 02/24 | 05/24 | | |
NCT05018650: A Randomized, Controlled Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical Reperfusion System (SUMMIT MAX) |
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| Active, not recruiting | N/A | 250 | US, RoW | Route 92 Medical Reperfusion System | Route 92 Medical, Inc. | Acute Ischemic Stroke | 06/24 | 06/24 | | |
NCT05232838: US Pilot Study of the CereVasc® EShunt® System in Normal Pressure Hydrocephalus |
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| Recruiting | N/A | 50 | US | eShunt Implant | CereVasc Inc, AlvaMed, Inc., Simplified Clinical Data Systems, LLC | Hydrocephalus, Normal Pressure, Hydrocephalus | 01/25 | 01/30 | | |
VANTAGE, NCT04391803: EvaLuate EndoVascular Treatment of Acutely Ruptured Shallow Intradural Aneurysms with the Pipeline™ Flex Embolization Device with Shield TEchnology™ (ELEVATE) |
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| Recruiting | N/A | 200 | NA | Pipeline™ Flex Embolization Device with Shield Technology™, Pipeline™ Shield Device | Medtronic Neurovascular Clinical Affairs | Intracranial Aneurysm, Ruptured Aneurysm | 01/26 | 01/27 | | |
EMBOLISE, NCT04402632: Embolization of the Middle Meningeal Artery with ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma |
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| Active, not recruiting | N/A | 600 | US | Surgical Management, Surgical Management + Treatment, No Treatment, Treatment | Medtronic Neurovascular Clinical Affairs | Subdural Hematoma | 12/24 | 03/25 | | |
| Recruiting | N/A | 2000 | Europe, US, RoW | EmboTrap® Revascularization Device, CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter, CEREGLIDE 71 Intermediate Catheter | Cerenovus, Part of DePuy Synthes Products, Inc. | Cerebral Stroke | 03/25 | 06/25 | | |
| Recruiting | N/A | 520 | US | Conventional Surgery, Middle Meningeal Artery Embolization (MMAE) | The University of Texas Medical Branch, Galveston, National Institute of Neurological Disorders and Stroke (NINDS) | Chronic Subdural Hematoma | 09/28 | 09/28 | | |
NCT04701684: WE-TRUST (Workflow Optimization to Reduce Time to Endovascular Reperfusion for Ultra-fast Stroke Treatment) |
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| Recruiting | N/A | 564 | Europe, US, RoW | Direct to Angio Suite (DTAS) Philips' CBCT triage, Conventional CT/MR triage | Philips Clinical & Medical Affairs Global | Stroke, Acute | 12/25 | 12/25 | | |
| Active, not recruiting | N/A | 246 | US | Treatment of Intracranial Aneurysms | Medtronic Neurovascular Clinical Affairs | Intracranial Aneurysm | 03/26 | 04/28 | | |
| Recruiting | N/A | 225 | Europe, US | Millipede System | Perfuze | Acute Ischemic Stroke | 07/25 | 10/25 | | |
CLASS, NCT05636124: Kaneka IED Coil System for the Treatment of Wide Necked Ruptured and Unruptured Intracranial Aneurysms |
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| Recruiting | N/A | 50 | US | Kaneka i-ED coil | Icahn School of Medicine at Mount Sinai, Kaneka Corporation | Intracranial Aneurysms, Wide Neck Intracranial Aneurysms | 07/25 | 07/25 | | |
CREST-2, NCT02089217: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial |
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| Active, not recruiting | N/A | 2486 | Europe, Canada, US, RoW | Carotid endarterectomy (CEA), Carotid Stenting (CAS), Intensive Medical Management - no CEA, Intensive Medical Management - no CAS | Thomas G. Brott, M.D., National Institute of Neurological Disorders and Stroke (NINDS) | Carotid Stenosis | 02/26 | 02/26 | | |
| Recruiting | N/A | 150 | US | Citadel Embolization Device | Stryker Neurovascular | Unruptured Wide-neck Aneurysms | 06/26 | 06/26 | | |
CAPTIVA-MRI, NCT05907629: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging |
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| Recruiting | N/A | 300 | US | MRI | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Stroke, Intracranial Atherosclerotic Stenosis (ICAS) | 03/29 | 03/29 | | |
| Recruiting | N/A | 2000 | Europe, US, RoW | EmboTrap® Revascularization Device, CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter | Cerenovus, Part of DePuy Synthes Products, Inc. | Cerebral Stroke | 07/24 | 10/24 | | |
| Campo-Bustillo, Iszet |
| Recruiting | 2/3 | 200 | Europe, Canada, US | Immediate mechanical thrombectomy(iMT) using EmboTrap Revascularization Device, EmboTrap III, Initial medical management (iMM) | Emory University, University of Calgary, University of Cincinnati, Heidelberg University, Children's Hospital Medical Center, Cincinnati | Cerebral Ischemia | 12/24 | 12/24 | | |
EMAGINE, NCT05044507: The Efficacy of a Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Subacute Ischemic Stroke Patients - a Pivotal Study (THE "" STUDY) |
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| Completed | N/A | 100 | US | BQ 2.0, BQ 2.0 sham stimulation group, BQ 2.0 active stimulation group | BrainQ Technologies Ltd. | Ischemic Stroke | 11/23 | 01/24 | | |
CAPTIVA-MRI, NCT05907629: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging |
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| Recruiting | N/A | 300 | US | MRI | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Stroke, Intracranial Atherosclerotic Stenosis (ICAS) | 03/29 | 03/29 | | |
| Desaro, Pamela |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Recruiting | 2 | 116 | Europe, US | Inebilizumab, UPLIZNA, Placebo | University of Utah | Autoimmune Encephalitis, Encephalitis | 10/25 | 08/26 | | |
| Stratoberdha, Melissa |
CAPTIVA-MRI, NCT05907629: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging |
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| Recruiting | N/A | 300 | US | MRI | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Stroke, Intracranial Atherosclerotic Stenosis (ICAS) | 03/29 | 03/29 | | |
| Escobar, Andrea |
CREST-H, NCT03121209: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics |
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| Active, not recruiting | 3 | 385 | Canada, US | Revascularization, Intensive Medical Management (IMM) alone | Columbia University, National Institute of Neurological Disorders and Stroke (NINDS), Mayo Clinic, University of Alabama at Birmingham, University of Maryland, University of California, Los Angeles | Internal Carotid Artery Stenosis, Cognitive Impairment | 01/27 | 07/27 | | |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Recruiting | 2 | 300 | US | TS23 | Translational Sciences, Inc., University of Cincinnati, National Institute of Neurological Disorders and Stroke (NINDS), Medical University of South Carolina, University of Arizona | Ischemic Stroke | 07/27 | 12/27 | | |
CREST-2, NCT02089217: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial |
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| Active, not recruiting | N/A | 2486 | Europe, Canada, US, RoW | Carotid endarterectomy (CEA), Carotid Stenting (CAS), Intensive Medical Management - no CEA, Intensive Medical Management - no CAS | Thomas G. Brott, M.D., National Institute of Neurological Disorders and Stroke (NINDS) | Carotid Stenosis | 02/26 | 02/26 | | |
| Recruiting | N/A | 3062 | US | CPAP | University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati | Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial | 11/26 | 11/26 | | |
| Mcdaneld, Logan |
| Completed | 4 | 3591 | Europe, US, RoW | theraputic heparin, unfractionated heparin, Enoxaparin, Dalteparin, Tinzaparin, Heparin, prophylactic heparin, enoxaparin, dalteparin, Fondparinux, P2Y12, Ticagrelor, Prasugrel, Clopidogrel, Crizanlizumab Injection, SGLT2 inhibitor, dapagliflozin, empagliflozin, canagliflozin, ertugliflozin | Matthew Neal MD, National Heart, Lung, and Blood Institute (NHLBI) | Covid19 | 08/23 | 01/24 | | |
| Recruiting | 3 | 700 | US | Apixaban, Eliquis, Aspirin | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Intracerebral Hemorrhage, Atrial Fibrillation | 04/27 | 04/27 | | |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Recruiting | N/A | 3062 | US | CPAP | University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati | Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial | 11/26 | 11/26 | | |
| Arora, Ajay |
| Recruiting | 3 | 700 | US | Apixaban, Eliquis, Aspirin | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Intracerebral Hemorrhage, Atrial Fibrillation | 04/27 | 04/27 | | |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Recruiting | N/A | 30000 | Europe | | King's College Hospital NHS Trust, King's College London | Neurological Disorder | 08/24 | 03/25 | | |
| Recruiting | N/A | 3062 | US | CPAP | University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati | Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial | 11/26 | 11/26 | | |
| Pagani, Rodrigo |
NCT04704141: Relationship of the Microenvironment and Male Fertility |
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| Not yet recruiting | N/A | 150 | US | Hormone replacement therapy | University of Illinois at Chicago | Male Infertility, Male Hypogonadism | 06/25 | 06/26 | | |
| Bradbury, Kristine |
NCT04450693: Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage, Complex Non-healing Diabetic Foot Ulcers (AMBULATE DFU II) |
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| Active, not recruiting | 3 | 220 | US | TTAX01, Standard care | BioTissue Holdings, Inc | Diabetic Foot Infection, Non-healing Wound, Non-healing Diabetic Foot Ulcer | 03/25 | 03/25 | | |
FLAMINGO-01, NCT05232916: Phase 3 Study to Evaluate the Efficacy and Safety of HER2/neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/neu Positive Subjects |
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| Recruiting | 3 | 750 | Europe, US | Placebo, GLSI-100 | Greenwich LifeSciences, Inc. | Breast Cancer | 12/26 | 12/26 | | |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Maley, Christine |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
NCT05489822: PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use. |
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| Recruiting | N/A | 20 | US | VERTICALE® Cervical System | Silony Medical GmbH | Degenerative Disc Disease (DDD), Instabilities, Trauma, Deformity | 01/26 | 04/26 | | |
CAPTIVA-MRI, NCT05907629: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging |
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| Recruiting | N/A | 300 | US | MRI | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Stroke, Intracranial Atherosclerotic Stenosis (ICAS) | 03/29 | 03/29 | | |
| Ibrahim, Khalil |
NCT05625503: Dilution of Verapamil During Intraarterial Administration |
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| Completed | 1 | 55 | US | Verapamil, Calcium channel blocker, Nicardipine | University of Illinois at Chicago | Vasospasm;Peripheral, Burning, Pain | 12/23 | 12/23 | | |
| Ohlander, Samuel |
NCT04704141: Relationship of the Microenvironment and Male Fertility |
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| Not yet recruiting | N/A | 150 | US | Hormone replacement therapy | University of Illinois at Chicago | Male Infertility, Male Hypogonadism | 06/25 | 06/26 | | |
| Atillo, Jefferson |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
NCT05232838: US Pilot Study of the CereVasc® EShunt® System in Normal Pressure Hydrocephalus |
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| Recruiting | N/A | 50 | US | eShunt Implant | CereVasc Inc, AlvaMed, Inc., Simplified Clinical Data Systems, LLC | Hydrocephalus, Normal Pressure, Hydrocephalus | 01/25 | 01/30 | | |
CAPTIVA-MRI, NCT05907629: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging |
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| Recruiting | N/A | 300 | US | MRI | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Stroke, Intracranial Atherosclerotic Stenosis (ICAS) | 03/29 | 03/29 | | |
| Holland, Amy |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Recruiting | 2 | 300 | US | TS23 | Translational Sciences, Inc., University of Cincinnati, National Institute of Neurological Disorders and Stroke (NINDS), Medical University of South Carolina, University of Arizona | Ischemic Stroke | 07/27 | 12/27 | | |
| Recruiting | N/A | 3062 | US | CPAP | University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati | Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial | 11/26 | 11/26 | | |
| Kozberg, Mariel |
| Recruiting | 3 | 700 | US | Apixaban, Eliquis, Aspirin | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Intracerebral Hemorrhage, Atrial Fibrillation | 04/27 | 04/27 | | |
| Tofovic, David |
CHANGE AFIB, NCT05130268: Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation |
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| Completed | 4 | 339 | US | Dronedarone, Multaq | American Heart Association, Duke Clinical Research Institute, Sanofi | Atrial Fibrillation | 01/24 | 06/24 | | |
| Active, not recruiting | 3 | 14013 | Europe, Canada, US, RoW | Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL, KJX839, Placebo in 1.5ml | Novartis Pharmaceuticals | Primary Prevention of Atherosclerotic Cardiovascular Disease | 04/29 | 04/29 | | |
| Chen, Yining |
CHANGE AFIB, NCT05130268: Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation |
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| Completed | 4 | 339 | US | Dronedarone, Multaq | American Heart Association, Duke Clinical Research Institute, Sanofi | Atrial Fibrillation | 01/24 | 06/24 | | |
| McCullough, Jada |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Abecassis, Isaac |
| Recruiting | 3 | 700 | US | Apixaban, Eliquis, Aspirin | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Intracerebral Hemorrhage, Atrial Fibrillation | 04/27 | 04/27 | | |
| Balinski, Mariah |
NCT06132412: Transcranial Direct Current Stimulation in Conjunction with Individualized Physical Therapy for Individuals with Chronic Knee Pain |
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| Recruiting | N/A | 30 | US | transcranial direct current stimulation, tDCS, physical therapy, PT | University of Illinois at Chicago | Knee Pain Chronic | 12/25 | 01/26 | | |
