The Aga Khan University Hospital
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 27 Trials 
28 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Bhutta, Zulfiqar A
NCT01908114: To Develop, Implement and Evaluate the Polio Demonstration Project Comprising of a Community Based Intervention Package for Polio Eradication in Pakistan

Active, not recruiting
4
60000
RoW
Enhanced Community mobilization, Combined Oral Polio Vaccine and Inject able Polio Vaccine during SIA
Aga Khan University, Pakistan Ministry of Health, Trust for Vaccines and Immunization, Pakistan, National Institutes of Health, Pakistan, Peshawar Medical College, World Health Organization, UNICEF, Bill and Melinda Gates Foundation
Polio, Polio Sero Conversion, Polio Sero Prevalence, Immunization Coverage
07/17
12/21
NCT03287882: Effect of Micronutrients and Life Skills Education on the Health and Nutrition of Adolescent and Young Women in Pakistan

Active, not recruiting
3
25447
RoW
Multiple micronutrients (UNIMMAP composition), UNICEF, Micronutrient tabs, pregnancy/PAC-1000, Life skills based education
Aga Khan University, The Hospital for Sick Children, National Program for Family Planning and Primary Health Care, Bill and Melinda Gates Foundation
Adolescents, Anemia, Pregnancy, Empowerment
03/21
02/22
KMC, NCT06130488: Implementation at Scale and Evaluation of

Completed
N/A
2500
RoW
KMC
Aga Khan University, Bill and Melinda Gates Foundation
Newborn Morbidity
07/23
07/23
UeN, NCT04184544: Scaling up Evidence Based MNCH Interventions : A Quasi Experimental Study Umeed e Nau () Project

Active, not recruiting
N/A
5000000
RoW
Improving of quality of care at health facility and outreach level
Aga Khan University, Bill and Melinda Gates Foundation, The Hospital for Sick Children
Maternal Complication of Pregnancy, Newborn Morbidity, Perinatal Problems
12/22
06/23
NCT05640050: Integrated Community Engagement and Audit Systems

Enrolling by invitation
N/A
1000
RoW
Audit Implementation
Aga Khan University, Bill and Melinda Gates Foundation
Maternal Death, Neonatal Death, Stillbirth
06/23
12/23
NCT05640063: Evaluation of Enhanced Delivery and Newborn Kit

Recruiting
N/A
2400
RoW
Enhanced Delivery and Newborn kit
Aga Khan University
Perinatal Death
12/23
12/23
MMiP, NCT05108675: Microbiome and Malnutrition in Pregnancy

Active, not recruiting
N/A
400
RoW
Aga Khan University, The Hospital for Sick Children, University of Toronto, University of Calgary, Dalhousie University, University of Alberta, Canadian Institutes of Health Research (CIHR)
Weight Gain, Pregnancy, Microbial Colonization, Pregnancy Related, Pregnancy Loss, Pregnancy Complications, Pregnancy; Parasitic Disease, Parasitic Disease, Microbial Disease, Infant Malnutrition, Malnutrition, Malnutrition in Pregnancy, Breastfeeding
12/24
12/24
NCT06025786: Impact Evaluation of Benazir Nashonuma Program (BNP) on Stunting Among Under-five Children

Recruiting
N/A
13200
RoW
Benazir Nashonuma Program (BNP)
Aga Khan University, International Food Policy Research Institute, Bill and Melinda Gates Foundation
Stunting, Wasting, Anemia, Nutrient Deficiency
12/25
06/26
NCT05135637: Naunehal - Integrated Immunization & MNCH Interventions; A Quasi-Experimental Study

Active, not recruiting
N/A
8100
RoW
Mobile health services, Private practitioner engagement for immunization, Community engagement and mobilization, Sehat Nishani - a health, nutrition and immunization app
The Hospital for Sick Children, Bill and Melinda Gates Foundation, Aga Khan University
Under Five Child Health Nutrition and Immunization
05/22
06/22
Hamid, Saeed S
D-LIVR, NCT03719313 / 2018-003167-54: Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2a

Completed
3
407
Europe, Canada, US, RoW
Lonafarnib, EBP994, Sarasar, LNF, Ritonavir, Norvir, RTV, PEG IFN-alfa-2a, Pegasys, pegylated interferon-alfa, Placebo Lonafarnib, Placebo Ritonavir
Eiger BioPharmaceuticals
Hepatitis Delta Virus
10/22
03/23
NCT04971538: HCV Self-testing in Pakistan

Recruiting
N/A
2000
RoW
OraQuick® HCV Self-Test
Foundation for Innovative New Diagnostics, Switzerland, Aga Khan University
Hepatitis C, Diagnostic Self Evaluation
03/22
04/22
NCT04943588: Treating Hepatitis C in Pakistan. Strategies to Avoid Resistance to Antiviral Drugs

Recruiting
N/A
25000
RoW
HCV RNA (PCR), HCV Antibody test (Point of care), AST/ALT and platelets measurement
Queen Mary University of London, Aga Khan University, Dow University of Health Sciences, University of Oxford, University of Bristol
Hepatitis C, Chronic
11/24
01/25
NCT05248919: Therapy for Hepatitis C Virus (HCV) in Primary Treatment Failure in Pakistan

Enrolling by invitation
N/A
318
RoW
Epclusa (nucleotide HCV NS5B polymerase inhibitors)., Sofosbuvir 400 Mg and Velpatasvir 100 Mg Oral Capsules
Queen Mary University of London, Aga Khan University, Dow University of Health Sciences, University of Oxford, University of Bristol
Hepatitis C
09/25
09/25
NCT06605573: Lay User Evaluation of the Panbio™ HCV Self-Test

Not yet recruiting
N/A
1185
NA
Panbio™ HCV Self Test, Fingerstick HIV testing (optional), Laboratory reference testing for HCV (immunoassays and PCR, CE marked)
Abbott Rapid Dx, Aga Khan University, Clinic 553 Karachi, Ezintsha Clinical Research Center
HEPATITIS C (HCV)
03/25
03/25
Ashley, Elizabeth
PHARC, NCT05972772: Rickettsia Clearance Study

Recruiting
2/3
72
RoW
Doxycyclin, vibramycin, Azithromycin, Zithromax
Lao-Oxford-Mahosot Hospital Wellcome Trust Research Unit, Mahidol Oxford Tropical Medicine Research Unit
Infectious Disease, Therapeutics
08/25
08/26
PLATCOV, NCT05041907: Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19

Recruiting
2
3800
RoW
Nirmatrelvir/ritonavir (e.g. PAXLOVID™), Nitazoxanide, Molnupiravir and nirmatrelvir/ritonavir (e.g. PAXLOVID™), Hydroxychloroquine, No treatment, Monoclonal antibodies, Fluoxetine, Molnupiravir, Sotrovimab, Ensitrelvir, Favipiravir, Ivermectin, Remdesivir, Atilotrelvir/ritonavir, Metformin, Nirmatrelvir/ritonavir, Nirmatrelvir
University of Oxford
COVID-19
01/27
01/27
AD ASTRA, NCT05648448: A Phase 2 Trial Comparing Antiviral Treatments in Early Symptomatic Influenza

Recruiting
2
3000
RoW
Oseltamivir, Favipiravir, Zanamivir, Baloxavir, Molnupiravir, Peramivir, Laninamivir, Oseltamivir and Baloxavir, Oseltamivir and Favipiravir, Favipiravir and Baloxavir
University of Oxford
Influenza, Influenza, Human
01/27
01/27
CefREC, NCT03895567: Study to Compare Blood Levels of Ceftriaxone Given by Suppository or Injection.

Not yet recruiting
1
37
RoW
A. Ceftriaxone (Roche ®) 500mg (slow intravenous injection), B. Ceftriaxone rectal dosage form test formulation 1 (1 x 500mg), C. Ceftriaxone rectal dosage form test formulation 2 (1 x 500mg)
University of Oxford, Biopharma (Orofino Pharmaceuticals Group)
Healthy
04/25
04/25
SPOT-SEPSIS, NCT04285021: Prediction of Disease Severity in Young Children Presenting With Acute Febrile Illness in Resource-limited Settings

Completed
N/A
3433
RoW
Medecins Sans Frontieres, Spain, Mahidol Oxford Tropical Medicine Research Unit, Gadjah Mada University, Laos-Oxford-Mahosot Wellcome Trust Research Unit, Cambodia Oxford Medical Research Unit, University of Medicine and Pharmacy at Ho Chi Minh City, Research Institute for Tropical Medicine, Philippines, International Centre for Diarrhoeal Disease Research, Bangladesh, Hanoi Medical University, Vietnam
Sepsis
11/22
11/22
SEACTN-WP-A, NCT04478578: Incidences, Causes, and Outcomes of Febrile Illness in Rural South and Southeast Asia

Recruiting
N/A
100000
RoW
University of Oxford, Medical Action Myanmar, Shoklo Malaria Research Unit, Lao-Oxford-Mahosot Hospital Wellcome Trust Research Unit, Building Resources Across Communities (BRAC), Bangladesh, Mahidol Oxford Tropical Medicine Research Unit, Action for Health Development (AHEAD)
Febrile Illness
12/24
12/24
SEACTN-WP-B, NCT04629053: Causes and Outcomes of Febrile Illness in Health Facilities in Rural South and Southeast Asia

Recruiting
N/A
7200
RoW
University of Oxford, Shoklo Malaria Research Unit (SMRU), Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Building Resources Across Communities (BRAC), Bangladesh, Mahidol Oxford Tropical Medicine Research Unit, Chiang Rai Clinical Research Unit (CCRU), Thailand
Acute Febrile Illness
12/24
12/24
Khan, Farhan R
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis

Recruiting
3
1683
US
Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management
University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca
Intracranial Arteriosclerosis, Stroke
05/28
05/28
SISTER, NCT05948566: Strategy for Improving Stroke Treatment Response

Recruiting
2
300
US
TS23
Translational Sciences, Inc., University of Cincinnati, National Institute of Neurological Disorders and Stroke (NINDS), Medical University of South Carolina, University of Arizona
Ischemic Stroke
07/27
12/27
NCT05529914: Effects of Myofascial Release and Neuromuscular Training for Pes Anserine Syndrome Associated With Knee Osteoarthritis

Completed
N/A
80
RoW
Myofascial release, Neuromuscular exercises, Cold pack, Cold pack therapy
Dow University of Health Sciences
Knee Osteoarthritis, Pes Anserine Bursitis
03/23
04/23
NCT05616702: Effectiveness of Pressure Biofeedback Therapy and Progressive Muscle Relaxation Technique in Improving Pain and Disability Among Patients With Non-Specific Low Back Pain

Recruiting
N/A
70
RoW
Pressure Biofeedback Therapy + Progressive Muscles Relaxation + thermotherapy, Progressive Muscles Relaxation + thermotherapy
Dow University of Health Sciences
Low Back Pain, Mechanical, Chronic Low-back Pain, Mechanical Low Back Pain, Lower Back Pain Chronic, Low Back Pain, CLBP - Chronic Low Back Pain, Pain, Chronic, Pain, Back
10/23
11/23
NCT05959902: Effectiveness of Physical Therapy in Stem Cell Transplant Recipients for Knee Osteoarthritis

Recruiting
N/A
48
RoW
Forward Walking, Physiotherapy Exercises
Dow University of Health Sciences
Knee Osteoarthritis, Osteo Arthritis Knee, OA Knee
11/23
12/23
Karkey, Abhilasha
PLATCOV, NCT05041907: Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19

Recruiting
2
3800
RoW
Nirmatrelvir/ritonavir (e.g. PAXLOVID™), Nitazoxanide, Molnupiravir and nirmatrelvir/ritonavir (e.g. PAXLOVID™), Hydroxychloroquine, No treatment, Monoclonal antibodies, Fluoxetine, Molnupiravir, Sotrovimab, Ensitrelvir, Favipiravir, Ivermectin, Remdesivir, Atilotrelvir/ritonavir, Metformin, Nirmatrelvir/ritonavir, Nirmatrelvir
University of Oxford
COVID-19
01/27
01/27
AD ASTRA, NCT05648448: A Phase 2 Trial Comparing Antiviral Treatments in Early Symptomatic Influenza

Recruiting
2
3000
RoW
Oseltamivir, Favipiravir, Zanamivir, Baloxavir, Molnupiravir, Peramivir, Laninamivir, Oseltamivir and Baloxavir, Oseltamivir and Favipiravir, Favipiravir and Baloxavir
University of Oxford
Influenza, Influenza, Human
01/27
01/27

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