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9 Trials

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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Cohen, Ezra
NCT02769520: Efficacy Study of Pembrolizumab in Relapsed, Locally Recurrent Squamous Cell Cancer of the Head and Neck	Active, not recruiting	2	27	US	Pembrolizumab, Keytruda	Assuntina Sacco, M.D., Merck Sharp & Dohme LLC	Squamous Cell Carcinoma of the Head and Neck	04/25	04/26
KEYNOTE-D38, NCT05077709: IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC	Active, not recruiting	2	63	Europe, US	IO102-IO103 in combination with pembrolizumab	IO Biotech, Theradex, Almac, NeoGenomics, Merck Sharp & Dohme LLC	Lung Cancer Non Small Cell, Head and Neck Squamous Cell Carcinoma, Urothelial Carcinoma Bladder	01/24	11/24
NCI-2018-01227, NCT03603223: Pembrolizumab in Treating Participants with Leukoplakia	Recruiting	2	26	US	Pembrolizumab, Keytruda, Lambrolizumab, MK-3475, SCH 900475	Jonsson Comprehensive Cancer Center, Merck Sharp & Dohme LLC	Erythroleukoplakia, Leukoplakia, Verrucous Oral Leukoplakia	08/25	08/26
PEMDA-HN, NCT05814666: Activity and Safety of Danvatirsen and Pembrolizumab in HNSCC	Recruiting	2	81	Europe, US, RoW	Danvatirsen, ISIS 481464, AZD9150, Pembrolizumab, Keytruda	Flamingo Therapeutics NV	HNSCC	05/25	05/26
NCT05743270: Study of RP3 in Combination With Nivolumab and Other Therapy in Patients With Locoregionally Advanced or Recurrent SCCHN	Withdrawn	2	130	Europe, US, RoW	RP3, CCRT(concurrent chemoradiation therapy), carboplatin and paclitaxel, nivolumab	Replimune Inc., Bristol-Myers Squibb	Squamous Cell Carcinoma of Head and Neck, Locally Advanced Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma	03/26	06/26
NCT04020185: Safety and Efficacy Study of IMSA101 in Refractory Malignancies	Completed	1/2	40	US	IMSA101, Immune checkpoint inhibitor (ICI), Immuno-oncology (IO) therapy	ImmuneSensor Therapeutics Inc.	Solid Tumor, Adult	09/23	09/23
Burgoyne, Adam M
ROWAN, NCT05063565 / 2021-001907-33: TheraSphere With Durvalumab and Tremelimumab for HCC	Recruiting	2	100	Europe, US	TheraSphere Y-90 glass microsphere therapy, Durvalumab (Imfinzi) immunotherapy, Tremelimumab immunotherapy	Boston Scientific Corporation, Biocompatibles UK Ltd	Hepatocellular Carcinoma	06/27	06/27
NCT05733598: Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced Unresectable or Metastatic HCC	Recruiting	2	30	US	RP2, Bevacizumab, Avastin, Atezolizumab, Tecentriq	Replimune Inc., Roche Pharma AG	Hepatocellular Carcinoma	12/27	07/28
NCT03715933: Phase 1 Study of INBRX-109 in Subjects with Locally Advanced or Metastatic Solid Tumors Including Sarcomas	Recruiting	1	321	Europe, US	INBRX-109, Carboplatin, Cisplatin, Pemetrexed, 5-fluorouracil, Irinotecan, Temozolomide	Inhibrx Biosciences, Inc	Colorectal Adenocarcinoma, Ewing Sarcoma	06/26	12/26