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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Abed, Madar
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy	Recruiting	N/A	620	US	OPTIMIZER Smart System	Impulse Dynamics	Heart Failure	03/26	03/26
Cribbs, Michael
FROST, NCT01992250: Cryoablation of Small Breast Tumors in Early Stage Breast Cancer	Recruiting	N/A	200	US	Visica 2 Treatment System, Visica Breast Therapy	Sanarus Technologies, Inc.	Breast Cancer	12/21	06/23
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy	Recruiting	N/A	620	US	OPTIMIZER Smart System	Impulse Dynamics	Heart Failure	03/26	03/26
Nasur, Ali
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy	Recruiting	N/A	620	US	OPTIMIZER Smart System	Impulse Dynamics	Heart Failure	03/26	03/26
NCT05412927: AngelMed Guardian® System PMA Post Approval Study	Recruiting	N/A	500	US	PMA P150009 AngelMed Guardian® System	Angel Medical Systems	Acute Coronary Syndrome	12/26	12/26
Willis, Christy
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy	Recruiting	N/A	620	US	OPTIMIZER Smart System	Impulse Dynamics	Heart Failure	03/26	03/26
NCT05412927: AngelMed Guardian® System PMA Post Approval Study	Recruiting	N/A	500	US	PMA P150009 AngelMed Guardian® System	Angel Medical Systems	Acute Coronary Syndrome	12/26	12/26
Oakes, Cailin
NCT04863664: Lead EvaluAtion for Defibrillation and Reliability (LEADR) / Lead Evaluation for Defibrillation and Reliability in Left Bundle Branch Area Pacing (LEADR LBBAP)	Recruiting	N/A	975	Europe, Canada, Japan, US, RoW	Defibrillation (RV Implant), Defibrillation (LBBAP Implant)	Medtronic Cardiac Rhythm and Heart Failure	Tachyarrhythmia	06/25	02/26
NCT05602454: Virtual Care to Improve Heart Failure Outcomes (VITAL-HF)	Active, not recruiting	N/A	178	US	Digital Heart Failure Medication Titration	Duke University, Story Health Inc.	Heart Failure With Reduced Ejection Fraction	04/25	04/25
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy	Recruiting	N/A	620	US	OPTIMIZER Smart System	Impulse Dynamics	Heart Failure	03/26	03/26