| Mahoney, Paul D |
| Recruiting | N/A | 1150 | US, RoW | Portico transcatheter aortic valve, Commercially available transcatheter aortic valve | Abbott Medical Devices | Aortic Valve Stenosis | 10/19 | 07/25 | | |
| Active, not recruiting | N/A | 572 | Europe, Canada, US | TriClipTM Device | Abbott Medical Devices | Tricuspid Regurgitation | 11/22 | 04/29 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
NCT03735667: ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement |
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| Active, not recruiting | N/A | 1948 | Canada, US | ACURATE neo2™ Transfemoral TAVR System, Medtronic CoreValve TAVR System, Edwards SAPIEN 3 TAVR System, ACURATE Prime™ Transfemoral TAVR System XL | Boston Scientific Corporation | Aortic Stenosis | 06/24 | 09/34 | | |
| Active, not recruiting | N/A | 1070 | Europe, US | Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure | 06/24 | 12/29 | | |
| Recruiting | N/A | 210 | US | Transseptal ViMAC, ViMAC | Mayra Guerrero | Mitral Annular Calcification, Mitral Stenosis, Mitral Regurgitation, Mitral Valve Disease | 12/24 | 12/24 | | |
NCT05295628: Evaluation of Safety and Effectiveness of the EMBLOK EPS During TAVR |
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| Recruiting | N/A | 532 | US | EMBLOK™ Embolic Protection System ("EMBLOK EPS"), SENTINEL™ Cerebral Protection System | Innovative Cardiovascular Solutions, Yale Cardiovascular Research Group | Aortic Valve Stenosis, Aortic Valve Disease, Aortic Valve Insufficiency, Aortic Valve Replacement | 01/25 | 02/25 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MitraClip™ device implantation, Mitral Valve Repair Surgery | Abbott Medical Devices | Mitral Valve Regurgitation | 04/26 | 04/34 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
REDUCE PAS, NCT03821129: GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study |
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| Recruiting | N/A | 636 | US | PFO closure with GORE® CARDIOFORM Septal Occluder | W.L.Gore & Associates | Stroke, PFO - Patent Foramen Ovale | 12/26 | 12/29 | | |
NCT03142152: The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR |
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| Recruiting | N/A | 300 | Europe, US | Carillon Mitral Contour System, Carillon, Percutaneous mitral valve repair, Guideline Directed Heart Failure Medication | Cardiac Dimensions, Inc. | Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases | 12/26 | 12/30 | | |
ENVISION, NCT05932615: IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation |
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| Enrolling by invitation | N/A | 1500 | Canada, US | Navitor Transcatheter Aortic Valve Implantation (TAVI) System, Any Commercially Available Transcatheter Aortic Valve (CAV) System | Abbott Medical Devices | Aortic Valve Stenosis, Heart Valve Diseases, Aortic Valve Disease, Heart Disease Structural Disorder | 04/27 | 04/36 | | |
| Zhang, Ming |
SHINY, NCT06157502: Shuxuening Injection in the Treatment With Intravenous Thrombolysis in Patients With Ischemic Stroke |
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| Recruiting | 3 | 1380 | RoW | Shuxuening Injection, Placebo | Beijing Tiantan Hospital | Ischemic Stroke, Acute | 06/25 | 12/26 | | |
TAPIS, NCT06316570: Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke |
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| Recruiting | 3 | 1380 | RoW | Early Dual Antiplatelet Therapy, Ticagrelor and Aspirin, Placebo, Placebo of Ticagrelor and Aspirin | Beijing Tiantan Hospital | Ischemic Stroke, Acute | 12/25 | 12/26 | | |
NCT05520177: A Phase III Study for 601 Versus Ranibizumab in Patients With Vision Loss |
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| Recruiting | 3 | 350 | RoW | 601 1.25mg, 601, ranibizumab 0.5mg, Lucentis | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | Branch Retinal Vein Occlusion | 12/25 | 12/25 | | |
NCT05297292: A Study to Evaluate the Efficacy and Safety of MW02 in the Treatment of nAMD |
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| Recruiting | 2/3 | 433 | RoW | MW02, Lucentis, ranibizumab | Mabwell (Shanghai) Bioscience Co., Ltd. | Wet Age-related Macular Degeneration | 05/23 | 06/24 | | |
| Completed | 1/2 | 60 | RoW | 2.5mg of BAT5906, 4.0mg of BAT5906 | Bio-Thera Solutions | Diabetic Macular Edema | 11/23 | 11/23 | | |
NCT05260385: To Evaluate KC1036 in the Patients with Advanced Digestive System Tumors |
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| Recruiting | 1/2 | 133 | RoW | KC1036 | Beijing Konruns Pharmaceutical Co., Ltd. | Digestive System Tumors | 10/25 | 12/25 | | |
| Recruiting | N/A | 192 | RoW | magnetic resonance image (MRI), serum | First Affiliated Hospital Xi'an Jiaotong University, NO.215 Hospital of Shaanxi Nuclear Industry, Baoji Zhongxin Hospital, Taihe Hospital | End Stage Renal Disease | 12/22 | 12/22 | | |
NCT05758623: Mg-containing Biodegradable Polymer Bone Repair Material |
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| Recruiting | N/A | 176 | RoW | Device | Shenzhen Zhongke Jingcheng Medical Technology Co., Ltd, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Chinese University of Hong Kong | Bone Deformity | 04/23 | 03/24 | | |
| Recruiting | N/A | 60 | RoW | Scanning with magnetic resonance imaging | First Affiliated Hospital Xi'an Jiaotong University | Hemifacial Spasm, Magnetic Resonance Imaging | 06/24 | 12/24 | | |
| Recruiting | N/A | 80 | RoW | physiotherapy and maxillary traction, massage therapy | First Affiliated Hospital Xi'an Jiaotong University | Neck Pain | 12/26 | 12/27 | | |
NCT06228196: Cohort Study of Clinical and Neuroimaging Characteristics for BPPV Patients in China |
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| Recruiting | N/A | 150 | RoW | Simultaneous cortico-spinal magnetic resonance imaging, Serum | First Affiliated Hospital Xi'an Jiaotong University | BPPV, Vertigo, Vertigo, Peripheral | 06/26 | 09/26 | | |
| Active, not recruiting | N/A | 1070 | Europe, US | Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure | 06/24 | 12/29 | | |
| Recruiting | N/A | 100 | Europe, Canada, US | Edwards APTURE transcatheter shunt system, Sham procedure | Edwards Lifesciences | Heart Failure | 01/26 | 07/30 | | |
| Recruiting | N/A | 870 | Canada, US | Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease | 12/27 | 12/31 | | |
NCT05090007: Imaging of Injury Mechanism and Interaction of Intestinal Bacteria in Children With Mild Traumatic Brain Injury |
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| Recruiting | N/A | 300 | RoW | magnetic resonance image, gut microbiota | First Affiliated Hospital Xi'an Jiaotong University, School of Life Science and Technology, Xi'an Jiaotong University, The Second Affiliated Hospital and Yuying Childern's Hospital of Wenzhou Medical University | MTBI - Mild Traumatic Brain Injury | 12/24 | 12/24 | | |
| Recruiting | N/A | 2000 | RoW | | China-Japan Friendship Hospital, Second Affiliated Hospital of Xi'an Jiaotong University, First Hospital of China Medical University, Henan Provincial People's Hospital, Second Xiangya Hospital of Central South University, Sichuan University, Southern Medical University, China, Ruijin Hospital, Wuhan Union Hospital, China | Chronic Obstructive Pulmonary Disease (COPD), Asthma, Bronchiectasis | 07/28 | 07/28 | | |
NCT05108909: Rapid Diagnosis and Prognosis Recognition of Imaging and Biomarkers in Mild to Moderate Traumatic Brain Injury |
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| Recruiting | N/A | 800 | RoW | MRI, CT, and serum biomarkers | First Affiliated Hospital Xi'an Jiaotong University, School of Life Science and Technology, Xi'an Jiaotong University, Second Affiliated Hospital of Wenzhou Medical University, Central South University, Xijing Hospital | MTBI - Mild Traumatic Brain Injury, Moderate Traumatic Brain Injury | 08/25 | 08/25 | | |
NCT05494190: The Management of Metastatic Neck Nodes in N2/3 Hypopharyngeal Squamous Cell Carcinoma |
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| Recruiting | N/A | 111 | RoW | Docetaxel, Cisplatin, Capecitabine, Concomitant chemoradiotherapy, Surgery | Eye & ENT Hospital of Fudan University, Shandong Provincial Hospital, Harbin Medical University Third Affiliated Hospital | Hypopharyngeal Carcinoma | 11/25 | 11/25 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MitraClip™ device implantation, Mitral Valve Repair Surgery | Abbott Medical Devices | Mitral Valve Regurgitation | 04/26 | 04/34 | | |
NCT05745805: Cohort Follow-up of Epidemic and Neuroimaging for Patients During the 1st Wave of the COVID-19 in China |
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| Recruiting | N/A | 600 | RoW | Simultaneous cortico-spinal magnetic resonance imaging, Serum | First Affiliated Hospital Xi'an Jiaotong University, Nuclear 215 Hospital of Shaanxi Province, Yanan Traditional Chinese Medicine Hospital, Shangluo Central Hospital, Xian QinHuang Hospital, Yulin No.2 Hospital, Hanzhong Central Hospital, Ankang Central Hospital, Baoji High-tech Hospital | COVID-19, Post-COVID-19 Syndrome, Acute COVID-19, Post-Acute COVID-19 | 06/26 | 09/26 | | |
BEST-BAO, NCT05631847: Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke |
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| Recruiting | N/A | 336 | RoW | Endovascular treatment, Intravenous thrombolysis (Alteplase) | Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital | Acute Ischemic Stroke, Basilar Artery Occlusion, Thrombosis, Alteplase, Endovascular Treatment | 01/27 | 05/27 | | |
| Caufield, Joanna |
COMPANION-002, NCT05506943: A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers |
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| Active, not recruiting | 2/3 | 150 | US | CTX-009, Paclitaxel | Compass Therapeutics | Biliary Tract Cancer, Cholangiocarcinoma, Gall Bladder Cancer, Ampullary Cancer | 07/25 | 12/25 | | |
NCT05242822: A Study to Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations |
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| Active, not recruiting | 1 | 54 | Europe, US, RoW | KIN-3248 | Kinnate Biopharma | Solid Tumor, Adult, Intrahepatic Cholangiocarcinoma, Urothelial Carcinoma | 06/26 | 09/26 | | |
