Yale Pediatric Endocrinology Clinic
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 5 Trials 
11 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Caprio, Sonia
NCT05067621: Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease

Recruiting
2
60
US
Semaglutide Pen Injector, Wegovy, Placebo
Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 2 Diabetes Mellitus, Impaired Glucose Tolerance, Non-Alcoholic Fatty Liver Disease, Obesity, Childhood
12/26
01/27
NCT03195400: Pathogenesis of Youth Onset Type 2 Diabetes and Prediabetes

Completed
N/A
100
US
Oral Glucose Tolerance Test, OGTT, Hyperglycemic Clamp, Infusion Study, Isoglycemic Intravenous Glucose Test, IsoG IVGT, Hyperinsulinemic Euglycemic Clamp and 2H20, E Clamp with labeled water
Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
IGT - Impaired Glucose Tolerance, T2D
08/21
08/22
NCT01725035: Hepatic De Novo Lipogenesis (DNL)in the Pathogenesis of Hepatic Steatosis in Obese Youth

Completed
N/A
60
US
Yale University, American Heart Association, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Hepatic Steatosis, Fatty Liver
08/22
08/22
NCT02004561: Comparison Between Gastric Band, Laparoscopic Sleeve Gastrectomy, Gastric Bypass Surgeries

Active, not recruiting
N/A
26
US
Yale University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Obese Adolescents
08/25
12/25
NCT02395003: Study to Investigate Adipocyte Cell and Lipid Turnover in Obese Adolescents

Completed
N/A
26
US
Palmitate Diet
Yale University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pediatric Obesity
03/23
03/23
NCT01967849: Prevalence of Carbohydrate Intolerance in Lean and Overweight/Obese Children

Completed
N/A
2500
US
Oral Glucose tolerance test
Yale University, National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Type 2 Diabetes
09/23
09/23
Weinzimer, Stuart A
NCT06449677: Bionic Pancreas in CFRD

Recruiting
3
150
US
iLet Bionic Pancreas System (BP), Usual Care (UC)
Jaeb Center for Health Research, Cystic Fibrosis Foundation, Massachusetts General Hospital, Beta Bionics, Inc.
Cystic Fibrosis-related Diabetes
11/25
03/26
NCT04959552: FSL2 Post Approval Study for Pediatric and Young Adults Patients

Recruiting
N/A
550
US
FreeStyle Libre 2
Abbott Diabetes Care
Diabete Mellitus
12/25
12/25
Glu-COACH, NCT06171412: a Peer-mentoring Intervention to Reduce Disparities in Continuous Glucose Monitor (CGM) Use

Recruiting
N/A
50
US
Glu-COACH, Enhanced standard-of-care (ESOC)
Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 1 Diabetes
02/27
02/27
Shaw, Melissa
UP-NEXT, NCT05329545: Upifitamab Rilsodotin Maintenance in Platinum-Sensitive Recurrent Ovarian Cancer

Terminated
3
20
Canada, US, RoW
Upifitimab rilsodotin, XMT-1536 Antibody Drug Conjugate, Placebo
Mersana Therapeutics, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT)
High Grade Serous Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
09/23
09/23
NCT04343417: Biorepository to Support Research in Kidney Diseases

Enrolling by invitation
N/A
1000
US
Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Acute Kidney Injury, Acute Interstitial Nephritis, Kidney Diseases
08/25
08/35
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Caprio, Sonia
NCT05067621: Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease

Recruiting
2
60
US
Semaglutide Pen Injector, Wegovy, Placebo
Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 2 Diabetes Mellitus, Impaired Glucose Tolerance, Non-Alcoholic Fatty Liver Disease, Obesity, Childhood
12/26
01/27
NCT03195400: Pathogenesis of Youth Onset Type 2 Diabetes and Prediabetes

Completed
N/A
100
US
Oral Glucose Tolerance Test, OGTT, Hyperglycemic Clamp, Infusion Study, Isoglycemic Intravenous Glucose Test, IsoG IVGT, Hyperinsulinemic Euglycemic Clamp and 2H20, E Clamp with labeled water
Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
IGT - Impaired Glucose Tolerance, T2D
08/21
08/22
NCT01725035: Hepatic De Novo Lipogenesis (DNL)in the Pathogenesis of Hepatic Steatosis in Obese Youth

Completed
N/A
60
US
Yale University, American Heart Association, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Hepatic Steatosis, Fatty Liver
08/22
08/22
NCT02004561: Comparison Between Gastric Band, Laparoscopic Sleeve Gastrectomy, Gastric Bypass Surgeries

Active, not recruiting
N/A
26
US
Yale University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Obese Adolescents
08/25
12/25
NCT02395003: Study to Investigate Adipocyte Cell and Lipid Turnover in Obese Adolescents

Completed
N/A
26
US
Palmitate Diet
Yale University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pediatric Obesity
03/23
03/23
NCT01967849: Prevalence of Carbohydrate Intolerance in Lean and Overweight/Obese Children

Completed
N/A
2500
US
Oral Glucose tolerance test
Yale University, National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Type 2 Diabetes
09/23
09/23
Weinzimer, Stuart A
NCT06449677: Bionic Pancreas in CFRD

Recruiting
3
150
US
iLet Bionic Pancreas System (BP), Usual Care (UC)
Jaeb Center for Health Research, Cystic Fibrosis Foundation, Massachusetts General Hospital, Beta Bionics, Inc.
Cystic Fibrosis-related Diabetes
11/25
03/26
NCT04959552: FSL2 Post Approval Study for Pediatric and Young Adults Patients

Recruiting
N/A
550
US
FreeStyle Libre 2
Abbott Diabetes Care
Diabete Mellitus
12/25
12/25
Glu-COACH, NCT06171412: a Peer-mentoring Intervention to Reduce Disparities in Continuous Glucose Monitor (CGM) Use

Recruiting
N/A
50
US
Glu-COACH, Enhanced standard-of-care (ESOC)
Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 1 Diabetes
02/27
02/27
Shaw, Melissa
UP-NEXT, NCT05329545: Upifitamab Rilsodotin Maintenance in Platinum-Sensitive Recurrent Ovarian Cancer

Terminated
3
20
Canada, US, RoW
Upifitimab rilsodotin, XMT-1536 Antibody Drug Conjugate, Placebo
Mersana Therapeutics, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT)
High Grade Serous Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
09/23
09/23
NCT04343417: Biorepository to Support Research in Kidney Diseases

Enrolling by invitation
N/A
1000
US
Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Acute Kidney Injury, Acute Interstitial Nephritis, Kidney Diseases
08/25
08/35

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