| Hunninghake, Gary |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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| Milstone, Aaron |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis |
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| Recruiting | 3 | 698 | Canada, US, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Progressive Pulmonary Fibrosis, Interstitial Lung Disease | 11/27 | 11/27 | | |
| Completed | 2 | 81 | Europe, Canada, US, RoW | CSL312, Factor XIIa antagonist monoclonal antibody, Garadacimab, Placebo | CSL Behring | Idiopathic Pulmonary Fibrosis | 01/24 | 01/24 | | |
NCT05032066: A Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects With Idiopathic Pulmonary Fibrosis |
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| Active, not recruiting | 2 | 153 | Europe, Canada, Japan, US, RoW | HZN-825, Placebo | Amgen | Idiopathic Pulmonary Fibrosis | 07/24 | 07/25 | | |
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NCT05671835: Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 2 | 75 | US | TTI-101, Placebo | Tvardi Therapeutics, Incorporated | Idiopathic Pulmonary Fibrosis | 03/25 | 07/25 | | |
NCT06283355: Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome |
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| Recruiting | 1 | 175 | US | Nasal Microbiota Transplant (NMT), Placebo | Johns Hopkins University | Staphylococcus Aureus, Microbial Colonization, Neonatal Infection | 06/26 | 12/26 | | |
NCT05695196: Feasibility and Safety Study of Parent-to-Child Nasal Microbiota Transplant |
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| Active, not recruiting | 1 | 34 | US | nasal microbiota transplant (NMT), Placebo | Johns Hopkins University, National Institute of Allergy and Infectious Diseases (NIAID) | Staphylococcus Aureus, Microbial Colonization, Neonatal Infection | 06/25 | 12/25 | | |
BrighT STAR, NCT04987840: A Multi-Center Diagnostic Stewardship Program to Improve Respiratory Culture Utilization in Critically Ill Children |
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| Enrolling by invitation | N/A | 15 | US | | Johns Hopkins University, National Institute of Allergy and Infectious Diseases (NIAID), Agency for Healthcare Research and Quality (AHRQ) | Ventilator Associated Pneumonia, Tracheobronchitis | 01/25 | 06/27 | | |
| Ettinger, Neil |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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| Active, not recruiting | 3 | 1667 | Europe, Canada, Japan, US, RoW | GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo, Standard of care (SoC), Pre-filled Syringes (PFS) | GlaxoSmithKline, Iqvia Pty Ltd | Asthma | 10/25 | 10/25 | | |
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TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis |
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| Recruiting | 3 | 698 | Canada, US, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Progressive Pulmonary Fibrosis, Interstitial Lung Disease | 11/27 | 11/27 | | |
SUVN-G3031, NCT04072380: A Study to Evaluate Safety, and Efficacy of (Samelisant) in Patients With Narcolepsy With and Without Cataplexy |
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| Completed | 2 | 190 | Canada, US | SUVN-G3031, Samelisant, Placebo | Suven Life Sciences Limited | Narcolepsy | 06/23 | 06/23 | | |
| Active, not recruiting | 2 | 129 | Europe, US, RoW | BBT-877, Placebo | Bridge Biotherapeutics, Inc. | Idiopathic Pulmonary Fibrosis | 01/25 | 09/25 | | |
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| Nair, Girish M |
| Active, not recruiting | 3 | 700 | Europe, Canada, US, RoW | Implantable Cardioverter Defibrillator + Usual Care, Implantable Cardioverter Defibrillator, ICD, Usual care, Standard medical therapy alone | University of Calgary, Canadian Institutes of Health Research (CIHR), Alberta Innovation and Science, Medtronic, GE Healthcare, Cardiac Arrhythmia Network of Canada, Accelerating Clinical Trials Consortium | Myocardial Infarction, Sudden Death | 12/24 | 12/24 | | |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis |
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| Recruiting | 3 | 698 | Canada, US, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Progressive Pulmonary Fibrosis, Interstitial Lung Disease | 11/27 | 11/27 | | |
| Recruiting | 2 | 66 | Europe, US | Reparixin 600mg, REP, Matching Placebo, Control | Dompé Farmaceutici S.p.A | Acute Respiratory Distress Syndrome, Adult | 08/25 | 08/25 | | |
NCT05571059: Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF) |
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| Recruiting | 2 | 128 | US | Ifetroban Sodium, ifetroban, Placebo | Cumberland Pharmaceuticals | Idiopathic Pulmonary Fibrosis | 01/26 | 01/26 | | |
IRM-ILD, NCT04119115: Integrated Radiographic and Metabolomics Risk Assessment in Patients With Interstitial Lung Diseases |
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| Terminated | N/A | 28 | US | CT-V, Quantitative lung function imaging and lung compliance imaging, Metabolites | William Beaumont Hospitals | Lung Diseases, Interstitial, Pulmonary Fibrosis | 10/22 | 10/22 | | |
NCT02150902: Augmented Wide Area Circumferential Catheter Ablation for Reduction of Atrial Fibrillation Recurrence |
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| Active, not recruiting | N/A | 411 | Canada | Wide area circumferential catheter ablation, WACA, Augmented- wide area circumferential ablation procedure, Augmented WACA | Ottawa Heart Institute Research Corporation | Atrial Fibrillation | 09/25 | 09/25 | | |
NEURO-AF, NCT02627183: Circulating BDNF in Patients With Atrial Fibrillation Undergoing Catheter Ablation or Exercise Training |
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| Recruiting | N/A | 200 | Canada | Catheter ablation, Exercise training | Ottawa Heart Institute Research Corporation | Atrial Fibrillation | 12/23 | 01/24 | | |
AWARE-2, NCT04823299: Patient Specific Ablation Strategy for Atrial Fibrillation (): A Randomized Clinical Trial |
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| Not yet recruiting | N/A | 390 | Canada | Cryoballoon ablation, Radiofrequency catheter ablation +EPS guided trigger and substrate ablation | Ottawa Heart Institute Research Corporation, McGill University, University of British Columbia | Atrial Fibrillation, Catheter Ablation, Radiofrequency Catheter Ablation | 09/26 | 09/26 | | |
| Kim, Hyun Soo |
COALA, NCT05383183: Efficacy and Safety of ChOline ALfoscerate in Patient With Mild to Moderate Alzheimer's Disease |
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| Recruiting | 4 | 630 | RoW | Choline Alfoscerate 400mg, Placebo | Daewoong Bio Inc. | Alzheimer Disease | 06/25 | 12/25 | | |
NCT05803941: Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer |
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| Recruiting | 4 | 700 | Europe, Canada, US, RoW | AAA617, lutetium (177Lu) vipivotide tetraxetan, [177Lu]Lu-PSMA-617, 177Lu-PSMA-617 | Novartis Pharmaceuticals | Prostate Cancer | 07/33 | 07/33 | | |
| Terminated | 3 | 372 | Europe, US, RoW | Pamrevlumab, FG-3019, Placebo | FibroGen | Idiopathic Pulmonary Fibrosis | 09/23 | 09/23 | | |
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| Active, not recruiting | 3 | 404 | Europe, Canada, Japan, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo | Chinook Therapeutics, Inc. | IgA Nephropathy, Immunoglobulin A Nephropathy | 12/26 | 12/26 | | |
PROUD, NCT05666804: Study Assessing the Efficacy and Safety of a Personalized Monotherapy Regimen of Brolucizumab in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy |
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| Recruiting | 3 | 160 | RoW | Brolucizumab 6mg, Beovu | Novartis Pharmaceuticals | Macular Polypoidal Choroidal Vasculopathy (PCV) | 09/25 | 09/25 | | |
| Recruiting | 3 | 778 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Crohn's Disease | 11/24 | 12/26 | | |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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PSMAddition, NCT04720157 / 2020-003968-56: An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With SoC, Versus SoC Alone, in Adult Male Patients With mHSPC |
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| Active, not recruiting | 3 | 1148 | Europe, Canada, Japan, US, RoW | 177Lu-PSMA-617, 68Ga-PSMA-11, ARDT, ADT | Novartis Pharmaceuticals, Alliance Foundation Trials, LLC., RTOG Foundation, Inc. | Prostatic Neoplasms | 07/25 | 02/26 | | |
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| Active, not recruiting | 3 | 202 | US | N-acetyl cysteine, NAC, Placebo | Weill Medical College of Cornell University, University of Virginia, University of Michigan, Pulmonary Fibrosis Foundation, University of Washington, National Heart, Lung, and Blood Institute (NHLBI), Three Lakes Foundation | Idiopathic Pulmonary Fibrosis | 12/25 | 12/25 | | |
TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis |
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| Recruiting | 3 | 698 | Canada, US, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Progressive Pulmonary Fibrosis, Interstitial Lung Disease | 11/27 | 11/27 | | |
NCT03132974: Evaluation of Efficacy and Safety of Single and Multiple Therapy of Herbal Medicine/Chuna Therapy on Non-specific Chronic Low Back Pain: A Study Protocol for Multicenter, 3-arm, Randomized, Single Blinded, Parallel Group, Incomplete Factorial Design, Pilot Study - |
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| Recruiting | 2/3 | 150 | RoW | Sogyeonghwalhyeol-tang granule, Sogyeonghwalhyeol-tang granule with manipulation procedure, Placebo with manipulation procedure | Gachon University Gil Oriental Medical Hospital, Daejeon University, Semyung University Korean Medicine Hospital in Chungju, Woosuk University Oriental Medical Center | Chronic Low Back Pain | 12/21 | 12/21 | | |
NCT06233461: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease |
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| Recruiting | 2 | 268 | Europe, Canada, Japan, US, RoW | TAK-279, Zasocitinib, Placebo | Takeda | Crohn's Disease | 09/26 | 07/27 | | |
NCT06254950: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis |
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| Recruiting | 2 | 207 | Europe, Canada, Japan, US, RoW | TAK-279, Zasocitinib, Placebo | Takeda | Ulcerative Colitis | 09/26 | 08/27 | | |
NCT04541173: Study of Atezolizumab and Bevacizumab With Y-90 TARE in Patients With Unresectable Hepatocellular Carcinoma (HCC) |
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| Terminated | 2 | 6 | US | Y-90 TARE, Atezolizumab, Tecentriq, Bevacizumab, Avastin | Aiwu Ruth He, MD, Georgetown University, Genentech, Inc. | Hepatocellular Carcinoma | 06/23 | 06/23 | | |
| Completed | 2 | 153 | Europe, Canada, US | TAK-062, Simulated Inadvertent Gluten Exposure (SIGE) Gluten-Bar, TAK-062 Placebo, Simulated Inadvertent Gluten Exposure (SIGE) Gluten-free Bar | Takeda | Celiac Disease | 11/24 | 11/24 | | |
NCT04162665: Pre-operative Adaptive Short Court Radiation Therapy in Gastric Cancer |
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| Recruiting | 2 | 36 | US, RoW | Adaptive short course radiation therapy, Standard of care chemotherapy regimen | Washington University School of Medicine, Viewray Inc. | Gastric Adenocarcinoma | 04/26 | 04/27 | | |
NCT04331041: Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma |
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| Recruiting | 2 | 42 | US | Adaptive stereotactic body radiation therapy, Adaptive SBRT, Defactinib, VS-6063, PF-04554878, Tumor biopsy, Research blood draw | Washington University School of Medicine, National Cancer Institute (NCI), Verastem, Inc. | Pancreas Cancer, Cancer of the Pancreas, Pancreas Adenocarcinoma | 06/27 | 06/28 | | |
NCT04166318: Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study |
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| Recruiting | 2 | 252 | US | Capecitabine, Ro 09-1978/000, Xeloda, Fluorouracil, 5 Fluorouracil, 5 Fluorouracilum, 5 FU, 5-Fluoro-2,4(1H, 3H)-pyrimidinedione, 5-Fluorouracil, 5-Fluracil, 5-FU, 5FU, AccuSite, Carac, Fluoro Uracil, Fluouracil, Flurablastin, Fluracedyl, Fluracil, Fluril, Fluroblastin, Ribofluor, Ro 2-9757, Ro-2-9757, Intensity-Modulated Radiation Therapy, IMRT, Intensity Modulated RT, Intensity-Modulated Radiotherapy, Mitomycin, Ametycine, MITO, MITO-C, Mito-Medac, Mitocin, Mitocin-C, Mitolem, Mitomycin C, Mitomycin-C, Mitomycin-X, Mitomycine C, Mitosol, Mitozytrex, Mutamycin, Mutamycine, NCI-C04706, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration | ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI) | Anal Basaloid Carcinoma, Anal Canal Cloacogenic Carcinoma, Anal Canal Squamous Cell Carcinoma, Anal Margin Squamous Cell Carcinoma, Stage I Anal Cancer AJCC v8, Stage IIA Anal Cancer AJCC v8 | 12/29 | 12/29 | | |
NCT02899091: Evaluation of the Safety and Potential Therapeutic Effects of CB-AC-02 in Patients With Alzheimer's Disease |
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| Active, not recruiting | 1/2 | 24 | RoW | CB-AC-02, Placebo | CHABiotech CO., Ltd | Alzheimer's Disease | 12/24 | 12/24 | | |
NCT05877430: Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer |
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| Recruiting | 1/2 | 160 | US, RoW | CJRB-101, Pembrolizumab injection | CJ Bioscience, Inc. | NSCLC, HNSCC, Melanoma, Metastatic Cancer, Advanced Solid Tumor, Advanced Cancer | 07/26 | 10/27 | | |
| Recruiting | 1/2 | 150 | Europe, US | 177Lu-rhPSMA-10.1 injection, 177Lu-rhPSMA-10.1, 18F-rhPSMA-7.3 injection, 18F-rhPSMA-7.3 | Blue Earth Therapeutics Ltd, PSI CRO | Prostate Cancer, Metastatic Castration-resistant Prostate Cancer, MCRPC, Urogenital Neoplasms, Prostatic Neoplasms, Prostatic Diseases | 08/26 | 10/26 | | |
NCT03516708: Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer |
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| Recruiting | 1/2 | 49 | US | Epacadostat, INCB024360, Short-course radiation therapy, SCRT, CAPOX chemotherapy, FOLFOX chemotherapy | Washington University School of Medicine, Incyte Corporation, National Cancer Institute (NCI) | Rectal Cancer | 07/27 | 08/30 | | |
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NCT05039905: SLN Detection With Tc-MSA-ICG in Lung Cancer Patients |
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| Recruiting | 1 | 10 | RoW | 99mTc-MSA-ICG | Korea University Guro Hospital | Lung Cancer | 12/21 | 12/21 | | |
NCT04046575: Radiation Dose Intensification With Accelerated Hypofractionated Intensity Modulated Radiation Therapy and Concurrent Carboplatin and Paclitaxel for Inoperable Esophageal Cancer |
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| Recruiting | 1 | 20 | US | Intensity Modulated Radiation Therapy, IMRT, Carboplatin, Paraplatin, MD Anderson Symptom Inventory (MDASI)-Plus module, EuroQol (EQ-5D), SF-12, MOS Social Support Measure, CES-D, Blood for ctDNA (optional), Blood for SCCA, Paclitaxel, Taxol | Washington University School of Medicine | Esophagus Cancer, Esophageal Cancer, Cancer of the Esophagus | 09/25 | 09/27 | | |
NCT06167941: Identification of Integrin ab Expression in Lung Cancer Patients |
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| Completed | N/A | 61 | RoW | Lung cancer types | Korea University Guro Hospital | Expression of Integrin ανβ3 in Lung Cancer | 09/21 | 11/21 | | |
NCT04441970: The Influence of Head and Neck Position on the Cuff Pressure Using Nasotracheal Tube |
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| Recruiting | N/A | 50 | RoW | Neutral position, Head extension position, Head flexion position, Head rotation position | Yonsei University | Adult Patients Over 20 Years of Age Who Require Intubation of the Nasotracheal Tube to Undergo Oral and Maxillofacial Surgery Under General Anesthesia | 12/20 | 03/21 | | |
NCT04499222: Assessment of Tube Position According to the Changes of Neck Position Between Two Different Types of Nasotracheal Tubes |
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| Not yet recruiting | N/A | 40 | RoW | Portex, Mallinckrodt | Yonsei University | Nasotracheal Intubation | 05/22 | 05/25 | | |
NCT03415919: Collection of Gastrointestinal Malignant and Non-malignant Human Samples |
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| Enrolling by invitation | N/A | 300 | US | no intervention will be given to patients. | University of Texas at Austin | Inflammatory Bowel Diseases, Colo-rectal Cancer | 07/22 | 07/22 | | |
NCT03962374: The Comparison of the Success Rate of the Endotracheal Intubation Between the Stylet and the Frova With Acute Angled Videolaryngoscope |
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| Recruiting | N/A | 166 | RoW | Frova, Stylet | Yonsei University | Anesthesia, General | 05/23 | 06/23 | | |
NCT05255588: A Stool DNA-based SDC2 Methylation Test for the Early Detection of Colorectal Cancer |
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| Recruiting | N/A | 2358 | RoW | EarlyTect® CRC test | Genomictree, Inc., Soon Chun Hyang University, Gangnam Severance Hospital, Kyung Hee University Hospital at Gangdong, Kangbuk Samsung Hospital, Kyung Hee University Hospital, Keimyung University Dongsan Medical Center, Korea University Anam Hospital, Pusan National University Hospital, The Catholic Univ. of Korea Bucheon ST. Mary's Hospital, Samsung Medical Center, Seoul National University Hospital, Asan Medical Center, Wonju Severance Christian Hospital, Severance Hospital | Colorectal Cancer, Advanced Colorectal Neoplasm, Advanced Adenomas, Non-neoplastic Polyps, Non-advanced Adenomas | 02/24 | 02/24 | | |
NCT05571982: Comparison of the Efficacy of Tidal Volume Breathing and Vital Capacity Breathing During High-flow Nasal Oxygen |
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| Not yet recruiting | N/A | 58 | RoW | Tidal volume breathing technique, Vital capacity breathing technique | Yonsei University | Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia | 09/23 | 09/24 | | |
ASSURE, NCT03306901: Chemoradiotherapy Versus Esophagectomy After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinoma |
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| Active, not recruiting | N/A | 240 | RoW | Esophagectomy, 5-fluorouracil, 5-FU, Cisplatin, Radiation therapy | Samsung Medical Center, Ministry of Health & Welfare, Korea | Esophageal Cancer | 12/25 | 12/33 | | |
NCT06583434: Effects of Stabilization-based Pilates Exercise on Gait and Balance in Women With Flexible Pesplanus |
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| Completed | N/A | 22 | RoW | core-lower extremity Pilates Training Group, Non-Training Group | Hyun Ju Kim | Flexible Flatfoot | 03/24 | 03/24 | | |
NCT05987007: Sleep Interventions and Neurocognitive Outcomes |
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| Not yet recruiting | N/A | 50 | US | Acoustic slow-wave activity enhancement, Cognitive behavioral therapy for insomnia | New York State Psychiatric Institute, Columbia University | Sleep Disturbance, Amnestic Mild Cognitive Impairment | 12/27 | 12/27 | | |
| Withdrawn | N/A | 10 | NA | Balloon-tipped catheter | Washington University School of Medicine | Esophageal Cancer, Kidney Cancer, Larynx Cancer, Liver Cancer, Lung Cancer, Digestive Organs--Cancer, Intrathoracic--Cancer, Respiratory Organs--Cancer, Pancreas Cancer, Small Intestine Cancer, Stomach Cancer, Colon Cancer, Rectal Cancer | 04/25 | 05/25 | | |
| Completed | N/A | 52 | US | Halcyon 4.0 system | Washington University School of Medicine, Varian Medical Systems | Brain Cancer, Head and Neck Cancer, Lung Cancer, Gastric Cancer, Ovarian Cancer, Colon Cancer | 10/24 | 10/24 | | |
| Recruiting | N/A | 10 | US | Proton SBRT | Washington University School of Medicine, The Foundation for Barnes-Jewish Hospital | Solid Tumor | 05/25 | 08/25 | | |
| Recruiting | N/A | 72 | RoW | Binaural sound | Gangnam Severance Hospital | General Anesthesia, Prostate Cancer Stage, Uterine Myoma | 02/25 | 02/25 | | |
NCT06705946: Effects of Water Inertia Load Training on Lower Limb Joint Moments, Gait, and Balance in Elderly Women |
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| Enrolling by invitation | N/A | 30 | RoW | Aqua vest group, Weight vest group | Hyun Ju Kim | Balance and Gait Impairment in Elderly Women | 02/25 | 02/25 | | |
IMPARC, NCT04827732: Hypofractionated Pencil-Beam Scanning Intensity-modulated Proton Therapy (IMPT) in Recurrent Rectal Cancer |
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| Recruiting | N/A | 23 | US | Hypofractionated Pencil-Beam Scanning Intensity-modulated Proton Therapy, IMPT, MEVION S250i Hyperscan and Adaptive Aperture Proton Therapy Machine | Washington University School of Medicine | Recurrent Rectal Cancer | 12/25 | 01/26 | | |
| Recruiting | N/A | 10000 | RoW | Biologic or targeted synthetic DMARD, etanercept, adalimumab, infliximab, golimumab, tocilizumab, abatacept, rituximab, ustekinumab, secukinumab, ixekizumab, or biosimilars, tofacitinib, baricitinib, upadacitinib | Seoul National University Hospital | Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis | 12/29 | 06/30 | | |
| Active, not recruiting | N/A | 63 | US | Radiation therapy, FOLFOX regimen, Functional Assessment of Cancer Therapy-Colorectal cancer (FACT-C) questionnaire, Rectal biopsy samples, Blood for ctDNA | Washington University School of Medicine | Adenocarcinoma of the Lower Rectum | 08/24 | 04/26 | | |
| Recruiting | N/A | 46 | RoW | Targeted therapeutic hypothermia, Targeted therapeutic normothermia | Wonju Severance Christian Hospital, National Research Foundation of Korea | Carbon Monoxide Poisoning, Neurologic Sequelae, Hypothermia | 12/24 | 07/25 | | |
| Recruiting | N/A | 134 | US | Daily Adaptive External Beam Radiation Therapy | Varian, a Siemens Healthineers Company, Washington University School of Medicine | Pancreatic Cancer | 02/26 | 02/28 | | |
NCT05369182: Multicenter Registry of Coronary Flow-Derived Indexes for Coronary Microvascular Disease (Multicenter FLOW-CMD Registry) |
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| Recruiting | N/A | 1000 | RoW | Invasive physiologic assessment, Intravascular imaging | Samsung Medical Center, Chonnam National University Hospital, Chosun University Hospital, Seoul National University Bundang Hospital, Seoul St. Mary's Hospital | Coronary Microvascular Disease, Coronary Artery Disease, Ischemic Heart Disease | 06/27 | 06/30 | | |
| Recruiting | N/A | 60 | US | Tumor collection via biopsy, Blood collection, Diffusion basis spectrum imaging (DBSI) magnetic resonance imaging (MRI), DBSI MRI | Washington University School of Medicine, National Cancer Institute (NCI) | Locally Advanced Cervical Carcinoma, Locally Advanced Cervical Cancer, Locally Advanced Pancreas Cancer, Locally Advanced Pancreatic Carcinoma, Locally Advanced Pancreatic Cancer, Cervical Cancer, Pancreas Cancer, Pancreatic Cancer, Cancer of the Cervix, Cancer of the Pancreas | 12/32 | 12/32 | | |
NCT05587114: Comparision of Various Biomarkers Between Peripheral and Pulmonary Blood |
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| Recruiting | N/A | 150 | RoW | frozen blood plasma samples | Korea University Guro Hospital | Lung Cancer, Diagnosis | 12/24 | 12/25 | | |
| Thavarajah, Krishna |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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| Belloli, Elizabeth |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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| Active, not recruiting | 3 | 202 | US | N-acetyl cysteine, NAC, Placebo | Weill Medical College of Cornell University, University of Virginia, University of Michigan, Pulmonary Fibrosis Foundation, University of Washington, National Heart, Lung, and Blood Institute (NHLBI), Three Lakes Foundation | Idiopathic Pulmonary Fibrosis | 12/25 | 12/25 | | |
NCT06265532: Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG Effect |
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| Recruiting | 1 | 22 | US | EGCG 300 mg, Dietary Supplement: EGCG Capsules with EGCG (at least 94% purity). 300 mg EGCG (2 capsules) taken orally daily for 12 weeks., Placebo for EGCG 300 mg, Dietary Supplement: Placebo Placebo (2 capsules) taken orally daily for 12 weeks., EGCG 600 mg, Dietary Supplement: EGCG Capsules with EGCG (at least 94% purity). 600 mg EGCG (4 capsules) taken orally daily for 12 weeks., Placebo for EGCG 600 mg, Dietary Supplement: Placebo Placebo (4 capsules) taken orally daily for 12 weeks. | Hal Chapman, Cornell University, Massachusetts General Hospital, University of Michigan, National Heart, Lung, and Blood Institute (NHLBI) | Idiopathic Pulmonary Fibrosis | 03/26 | 03/26 | | |
NCT05195918: Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients |
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| Recruiting | 1 | 50 | US | EGCG 300 mg + Nintedanib, epigallocatechin-3-gallate + Ofev, EGCG 300 mg + Pirfenidone, epigallocatechin-3-gallate + Esbriet, Placebo 2 capsules + Nintedanib or Pirfenidone, Placebo + Ofev or Esbriet, EGCG 600 mg + Nintedanib, EGCG 600 mg + Pirfenidone, Placebo 4 capsules + Nintedanib or Pirfenidone | Hal Chapman, University of Michigan, Cornell University, Massachusetts General Hospital, Temple University, University of Washington, University of Virginia | Idiopathic Pulmonary Fibrosis | 04/26 | 04/26 | | |
PHINDER, NCT05776225: Pulmonary Hypertension Screening in Patients With Interstitial Lung Disease for Earlier Detection |
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| Recruiting | N/A | 200 | US | Right heart catheterization (RHC) | United Therapeutics | Interstitial Lung Disease, Pulmonary Hypertension | 04/25 | 06/25 | | |
| Ginns, Leo |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis |
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| Recruiting | 3 | 698 | Canada, US, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Progressive Pulmonary Fibrosis, Interstitial Lung Disease | 11/27 | 11/27 | | |
| Recruiting | N/A | 660 | US | Personalized Cardiopulmonary Rehabilitation, Structured Pacing, Education, Usual Care | Duke University, National Heart, Lung, and Blood Institute (NHLBI) | Long COVID, Long Covid19, Long Covid-19 | 10/25 | 01/26 | | |
| Hereford, Sherae |
NCT03694158: Investigating Dupilumab's Effect in Asthma by Genotype |
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| Recruiting | 4 | 150 | US | Dupilumab, Dupixent®, Placebo | Boston Children's Hospital, National Institute of Allergy and Infectious Diseases (NIAID), Regeneron Pharmaceuticals, HealthBeacon Plc, Merck Sharp & Dohme LLC, Sanofi | Asthma | 09/26 | 03/27 | | |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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NCT06004440: Real World Registry for Use of the Ion Endoluminal System |
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| Recruiting | N/A | 3000 | US | Ion Endoluminal System | Intuitive Surgical | Lung Cancer, Multiple Pulmonary Nodules, Lung Neoplasms, Respiratory Tract Neoplasms, Thoracic Neoplasms, Neoplasms by Site, Neoplasms, Lung Diseases, Respiratory Tract Diseases | 08/26 | 08/27 | | |
| DeGrote, Mandi |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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IPF-PRO, NCT01915511: Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry |
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| Recruiting | N/A | 3000 | US | | Duke University, Boehringer Ingelheim | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 01/28 | 01/28 | | |
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| DeGrote, Amanda |
TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis |
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| Recruiting | 3 | 698 | Canada, US, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Progressive Pulmonary Fibrosis, Interstitial Lung Disease | 11/27 | 11/27 | | |
| Shipp, Anna |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis |
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| Recruiting | 3 | 698 | Canada, US, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Progressive Pulmonary Fibrosis, Interstitial Lung Disease | 11/27 | 11/27 | | |
NCT05671835: Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 2 | 75 | US | TTI-101, Placebo | Tvardi Therapeutics, Incorporated | Idiopathic Pulmonary Fibrosis | 03/25 | 07/25 | | |
| Rahimi, Layla |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis |
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| Recruiting | 3 | 698 | Canada, US, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Progressive Pulmonary Fibrosis, Interstitial Lung Disease | 11/27 | 11/27 | | |
| Briggs, Linda |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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| Moua, Teng |
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 576 | Canada, US | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 06/25 | 06/25 | | |
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TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis |
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| Recruiting | 3 | 698 | Canada, US, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Progressive Pulmonary Fibrosis, Interstitial Lung Disease | 11/27 | 11/27 | | |
NCT06317285: A Study to Evaluate the Efficacy and Safety of GSK3915393 in Participants With Idiopathic Pulmonary Fibrosis (IPF) |
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| Recruiting | 2 | 150 | Europe, Canada, US, RoW | GSK3915393, Placebo | GlaxoSmithKline | Idiopathic Pulmonary Fibrosis | 03/26 | 03/26 | | |
NCT05130034: Home-based Pulmonary Rehabilitation and Health Coaching in Fibrotic Interstitial Lung Disease |
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| Enrolling by invitation | N/A | 80 | US | Home-based pulmonary rehabilitation | Mayo Clinic, Boehringer Ingelheim | Fibrotic Interstitial Lung Disease | 02/25 | 02/25 | | |
| Recruiting | N/A | 135 | US | | National Jewish Health, University of California, Davis, Mayo Clinic, University of Chicago, University of Texas Southwestern Medical Center, University of Arizona, University of Utah | Hypersensitivity Pneumonitis | 01/25 | 01/26 | | |
| Mello, Curtis |
| Completed | 4 | 40 | Europe, US | dupilumab, Dupixent®, SAR231893, Matching placebo | Regeneron Pharmaceuticals | Asthma | 07/23 | 07/23 | | |
ACHIEVE-4, NCT05803421: A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk |
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| Active, not recruiting | 3 | 2749 | Europe, US, RoW | Orforglipron, LY3502970, Insulin Glargine | Eli Lilly and Company | Type 2 Diabetes, Obesity, Overweight or Obesity, Overweight, Cardiovascular Diseases, Chronic Kidney Disease | 09/25 | 01/26 | | |
| Active, not recruiting | 3 | 1667 | Europe, Canada, Japan, US, RoW | GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo, Standard of care (SoC), Pre-filled Syringes (PFS) | GlaxoSmithKline, Iqvia Pty Ltd | Asthma | 10/25 | 10/25 | | |
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TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis |
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| Recruiting | 3 | 698 | Canada, US, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Progressive Pulmonary Fibrosis, Interstitial Lung Disease | 11/27 | 11/27 | | |
