| Terminated | 2 | 92 | Europe, Japan, US, RoW | BIIB093, Glibenclamide, CIRARA, RP 1127, Placebo | Remedy Pharmaceuticals, Inc. | Brain Contusion | 06/23 | 06/23 | | |
| Recruiting | N/A | 1094 | Canada, US | ICP + PbtO2 guided management strategy, ICP guided management strategy | University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), University of Washington, University of Pennsylvania, University of Pittsburgh, Medical University of South Carolina | Brain Injuries, Traumatic | 11/27 | 11/27 | | |