University Hospitals Cleveland
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 44 Trials 
105 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Dowlati, Afshin
ASTRIDE, NCT05468489: To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC

Recruiting
3
200
US
Serplulimab + chemotherapy (carboplatin-etoposide), Atezolizumab + chemotherapy (carboplatin-etoposide)
Shanghai Henlius Biotech
Extensive Stage Small Cell Lung Cancer
04/25
12/25
NCT02795923: Nivolumab Alone or in Combination With Decitabine/Tetrahydrouridine in Non-small Cell Lung Cancer

Not yet recruiting
2
60
US
Nivolumab, Opdivo, oral decitabine, decitabine, DEC, Dacogen, Tetrahydrouridine, THU
Yogen Saunthararajah
Lung Cancer, Non-small Cell Lung Cancer
12/18
12/18
NCT05027867 / 2021-001530-19: KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancer

Terminated
2
3
Europe, US, RoW
KRT-232, navtemadlin
Kartos Therapeutics, Inc.
Small-cell Lung Cancer, Small Cell Lung Carcinoma, Small Cell Lung Cancer Extensive Stage, Small Cell Lung Cancer Recurrent
08/22
08/22
NCT04010357: Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC

Recruiting
2
29
US
Abemaciclib,, LY2835219
Case Comprehensive Cancer Center
Small-cell Lung Cancer, Large Cell Neuroendocrine Carcinoma of the Lung, Extrapulmonary Small Cell Carcinoma
06/25
06/25
NCI-2021-14403, NCT05198830: Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Recruiting
2
42
US
Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Durvalumab, Imfinzi, Immunoglobulin G1, Anti-(Human Protein B7-H1) (Human Monoclonal MEDI4736 Heavy Chain), Disulfide with Human Monoclonal MEDI4736 Kappa-chain, Dimer, MEDI 4736, MEDI-4736, MEDI4736, FDG-Positron Emission Tomography, FDG, FDG-PET, FDG-PET Imaging, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Methoxyamine, TRC102 Base, Pemetrexed, MTA, Multitargeted Antifolate, Pemfexy, Radiation Therapy, Cancer Radiotherapy, Energy Type, ENERGY_TYPE, Irradiate, Irradiated, Irradiation, Radiation, Radiation Therapy, NOS, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation
National Cancer Institute (NCI)
Lung Adenocarcinoma, Lung Large Cell Carcinoma, Lung Non-Squamous Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8
12/25
12/25
HPN328-4001, NCT04471727: A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/)

Recruiting
1/2
232
US
MK-6070, HPN328, Atezolizumab, Ifinatamab Deruxtecan (I-DXd), DS-7300a, MK-2400
Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA), Daiichi Sankyo
Small-Cell Lung Cancer, Neuroendocrine Carcinoma
02/26
02/26
NCT05142696: A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab

Recruiting
1/2
200
Europe, US
[177Lu]Lu-DOTA-TATE, Lutathera, Lutetium (177Lu) oxodotreotide, Lutetium Lu 177 dotatate, Atezolizumab, [68Ga]Ga-DOTA-TATE, Carboplatin, Etoposide
Novartis Pharmaceuticals
Extensive Stage Small Cell Lung Cancer
06/29
06/29
BT7480-100, NCT05163041: Study in Patients With Advanced Malignancies Associated With Nectin-4 Expression

Active, not recruiting
1/2
200
Europe, US
BT7480, Nivolumab
BicycleTx Limited
Advanced Solid Tumor
09/25
12/25
NCT02007382: Study of Trametinib in Advanced Cancer Patients With Hepatic Dysfunction

Recruiting
1
68
US, Canada
Trametinib, GSK1120212
University Health Network, Toronto, National Cancer Institute (NCI)
Solid Tumors, Hepatic Dysfunction
06/15
12/15
CPI-300, NCT04808453: Phase I Study of in Patients With Advanced Tumors

Completed
1
17
US
CPI-300
Coordination Pharmaceuticals, Inc.
Advanced Tumors
12/23
12/23
NCT05130255: GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2

Recruiting
1
60
US
GD2-SADA:177Lu-DOTA Complex, two-step radioimmunotherapy
Y-mAbs Therapeutics
SCLC, Malignant Melanoma, Sarcoma, High Risk Neuroblastoma
03/27
04/27
NCT05580172: Phase 1 Study of Oral RH324 in Advanced Non-Small Cell Lung Cancer

Recruiting
1
6
US
RH324
ReHeva Biosciences,Inc.
Safety Issues
06/24
01/25
TEAD-AST-101, NCT06251310: SW-682 in Advanced Solid Tumors

Recruiting
1
186
US
SW-682, Combination Therapy
SpringWorks Therapeutics, Inc.
Advanced Solid Tumor, Mesothelioma, Malignant
01/30
06/30
SGNB6A-001, NCT04389632: A Study of SGN-B6A in Advanced Solid Tumors

Recruiting
1
824
Europe, US, RoW
sigvotatug vedotin, SGN-B6A, pembrolizumab, Keytruda, cisplatin, carboplatin
Seagen Inc.
Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck, HER2 Negative Breast Neoplasms, Esophageal Squamous Cell Carcinoma, Esophageal Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Ovarian Neoplasms, Cutaneous Squamous Cell Cancer, Exocrine Pancreatic Adenocarcinoma, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Stomach Neoplasms
11/26
02/28
NCT05571969: Study to Determine the Maximum Tolerated Dose (MTD) of PARPi 2X-121 Monotherapy and the MTD of Dovitinib in Combination With 2X-121 in Patients With Advanced Solid Tumors

Suspended
1
40
US
2X-121 and dovitinib
Allarity Therapeutics, Amarex Clinical Research
Advanced Solid Tumors
10/24
03/25
SGNSTNV-001, NCT04665921: A Study of SGN-STNV in Advanced Solid Tumors

Terminated
1
111
Europe, Canada, US
SGN-STNV
Seagen Inc.
Carcinoma, Non-Small Cell Lung, HER2 Negative Breast Neoplasms, Ovarian Neoplasms, Uterine Cervical Neoplasms, Endometrial Neoplasms, Esophageal Neoplasms, Gastroesophageal Junction Carcinoma, Stomach Neoplasms, Colorectal Neoplasms, Exocrine Pancreatic Adenocarcinoma, Appendiceal Adenocarcinoma, Pseudomyxoma Peritonei
03/24
03/24
SGNPDL1V-001, NCT05208762: A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

Recruiting
1
438
Europe, Canada, US
PF-08046054, SGN-PDL1V, pembrolizumab, Keytruda
Seagen Inc.
Carcinoma, Non-Small-Cell Lung, Squamous Cell Carcinoma of the Head and Neck, Esophageal Squamous Cell Carcinoma, Ovarian Neoplasms, Melanoma, Triple Negative Breast Neoplasms, Gastric Cancer
07/25
12/27
ALCHEMIST Screening, NCT02194738: Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The Trial)

Recruiting
N/A
8300
US, RoW
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Clinical Observation, observation, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Crizotinib, Alkixen, Crizocent, MET Tyrosine Kinase Inhibitor PF-02341066, PF 02341066, PF-02341066, PF-2341066, PF02341066, Xalkori, Cytology Specimen Collection Procedure, Cytologic Sampling, Echocardiography, EC, Erlotinib, Gemcitabine Hydrochloride, dFdCyd, Difluorodeoxycytidine Hydrochloride, Gemcitabine HCI, Gemzar, LY 188011, LY-188011, LY188011, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat, Pembrolizumab, BCD-201, GME 751, GME751, Keytruda, Lambrolizumab, MK 3475, MK-3475, MK3475, Pembrolizumab Biosimilar BCD-201, Pembrolizumab Biosimilar GME751, Pembrolizumab Biosimilar QL2107, Pembrolizumab Biosimilar RPH-075, QL2107, RPH 075, RPH-075, RPH075, SCH 900475, SCH-900475, SCH900475, Pemetrexed, MTA, Multitargeted Antifolate, Pemfexy, Pemetrexed Disodium, Alimta, Almita, LY231514, N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium Salt, Placebo Administration, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT
National Cancer Institute (NCI)
Stage IB Lung Non-Small Cell Carcinoma AJCC v7, Stage II Lung Non-Small Cell Cancer AJCC v7, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIA Lung Non-Small Cell Cancer AJCC v7, Stage IIIB Lung Cancer AJCC v8
09/26
09/26
Hayek, Salim
SERENITY CM, NCT05614648: Sciatica Epidural Radiculopathy Experimental New Interventional TherapY Clonidine Micropellet

Terminated
3
17
US
Clonidine Micropellets, Tuohy epidural needle
Sollis Therapeutics, Inc.
Lumbosacral Radiculopathy
03/24
03/24
ATRIUM, NCT05335928: Abatacept in Immune Checkpoint Inhibitor Myocarditis

Recruiting
3
390
Canada, US
Abatacept plus, Orencia, Placebo
Massachusetts General Hospital, Bristol-Myers Squibb
Myocarditis Acute, Cancer
11/26
04/27
NCT05815485: A Randomized, Double-Blind, Placebo-Controlled Phase 2/3 Study to Determine the Safety and Effectiveness of Azeliragon in the Treatment of Patients Hospitalized for Coronavirus Disease 2019 (COVID-19) or Pneumonia

Recruiting
2/3
144
US
Azeliragon, Placebo
Salim S. Hayek
COVID-19
04/26
04/26
NCT05469074: Noninvasive Brain Stimulation for Diabetic Neuropathic Pain

Recruiting
2
80
US
Active tDCS + Active TUS, Device: Sham
Case Western Reserve University, Highland Instruments, Inc.
Diabetic Neuropathies, Chronic Pain
08/23
08/24
ISIC, NCT04818866: International Study of Inflammation in COVID-19

Completed
N/A
4463
US
SuPAR, C-reactive protein, Ferritin, D-Dimer, Procalcitonin, Interleukin-6, Lactate Dehydrogenase
University of Michigan, Rush University, Copenhagen University Hospital, Hvidovre, University of Athens, Heinrich-Heine University, Duesseldorf, University of Thessaly, Charite University, Berlin, Germany
Covid19, Outcome, Fatal, Respiratory Failure, Acute Kidney Injury, Inflammation
12/22
12/22
M2C2, NCT04706533: Michigan Medicine COVID-19 Cohort: Clinical Characteristics, Inflammatory Markers and Outcomes of Patients Hospitalized for COVID-19

Completed
N/A
3402
US
Biomarkers of inflammation
University of Michigan
Covid19, Kidney Diseases, Inflammation, SARS-CoV Infection
12/22
12/22
NCT05469438: IMAS Optimization and Applicability in an Acute Stroke Setting.

Active, not recruiting
N/A
30
US
Case Western Reserve University, Highland Instruments, Inc.
Acute Stroke
08/23
09/25
KIDCOV, NCT04705766: KIDney Injury in Times of COVID-19

Recruiting
N/A
2000
US
Urine Collection
University of California, San Francisco, Rush University Medical Center, University of Michigan, University of California
SARS-CoV Infection, Covid19, Corona Virus Infection, Acute Kidney Injury, Kidney Injury
03/26
03/26
NCT03625752: Optimization of NIBS for Diabetic Neuropathy Neuropathic Pain

Recruiting
N/A
60
US
Active Comparator: Active tDCS + Active TUS, Sham
Case Western Reserve University, Highland Instruments, Inc.
Diabetic Neuropathies, Chronic Pain
12/24
05/25
NCT05811143: Examining the Effects of Dorsal Column Stimulation on Pain From Lumbar Spinal Stenosis Related to Epidural Lipomatosis.

Completed
N/A
3
US
Spinal Cord Stimulator
University Hospitals Cleveland Medical Center
Lipomatosis, Low Back Pain
01/24
01/24
RESTORE, NCT04803214: ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation

Active, not recruiting
N/A
203
US
ReActiv8
Mainstay Medical
Chronic Low-back Pain
09/24
01/26
NCT05945121: Prehabilitation Program to Improve Cardiac Reserve in High-Risk Patients Undergoing Hematopoietic Stem Cell Transplantation

Recruiting
N/A
10
US
Cardio-oncology program
University of Michigan Rogel Cancer Center, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI)
Hematopoietic Stem Cell Transplant
08/27
08/27
Roselli, Eric
NCT03884634: Efficacy of the Dabir Surfaces Micropressure Overlay for Decubitus Ulcer Prevention During Cardiac Surgery

Completed
N/A
6627
US
Dabir Micropressure Overlay
The Cleveland Clinic
Pressure Ulcer, Pressure Injury
10/21
09/22
RelayBranch, NCT03214601: Early Feasibility Study of the Thoracic Stent-Graft System

Active, not recruiting
N/A
30
US
penetrating atherosclerotic ulcer, aorta branch cardiovascular implant, Relay Branch System, system, endovascular graft, aortic aneurysm treatment
Bolton Medical
Thoracic Aorta Aneurysm, Aneurysm, Ruptured, Aortic Aneurysm
09/23
08/28
NCT06780241: Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease

Recruiting
N/A
200
US
CMR, Quality of Life Questionnaire
The Cleveland Clinic
Aortic Regurgitation, Mitral Regurgitation, Aortic Stenosis
12/30
12/30
MANTRA, NCT05002543: CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

Recruiting
N/A
2150
Europe, Canada, US, RoW
Corcym S.r.l
Cardiac Valve Disease
08/25
12/35
B-SAFER, NCT04747626: Branched Stented Anastomosis Frozen Elephant Trunk Repair

Recruiting
N/A
490
US
B-SAFER
Eric Roselli, M. D., The Cleveland Clinic
Thoracic Aortic Aneurysm, Aortic Dissection, Congenital Aortic Anomaly
12/27
12/27
ARISEII, NCT05800743: Evaluation of the GORE® Ascending Stent Graft

Enrolling by invitation
N/A
370
US
GORE® Ascending Stent Graft (ASG device), GORE® Thoracic Aortic Graft Thoracic Branch Endoprosthesis (TBE Device), Revascularization Procedure, Surgery
W.L.Gore & Associates
Aortic Aneurysm, Thoracic, Pseudoaneurysm, Aortic Dissection, Aorta; Lesion
10/29
01/34
MacLeish, Sarah A
NCT05714059: Safety and Effectiveness of the MiniMed™ 780G System With DS5 CGM

Completed
N/A
250
US
Insulin Pump with Continuous Glucose Monitoring
Medtronic Diabetes
Type 1 Diabetes
12/23
12/23
SUCCEED2, NCT06604871: Safety Evaluation of MiniMed™ 780G System with DS5 CGM in Children

Recruiting
N/A
60
US
Insulin Pump with Continuous Glucose Monitoring
Medtronic Diabetes
Type 1 Diabetes
06/25
06/25
NCT06074458: GO TEAM: Glucose Optimization Through Technology Assisted Management

Recruiting
N/A
60
US
Glucosano, Community Health Worker diabetes technology coach
Sarah MacLeish, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), KeborMed
Type 1 Diabetes
10/26
10/26
Markowitz, Alan
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
N/A
1056
Europe, Canada, US
Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Medtronic Cardiovascular
Mitral Valve Regurgitation
10/26
09/36
NCT04073420: Medtronic Cardiac Surgery PMCF Registry

Recruiting
N/A
2700
Europe, US
Surgical Heart Valve Repair Products, Surgical Heart Valve Replacement Products
Medtronic Cardiac Surgery
Valve Disease, Heart
12/39
12/39
Ahuja, Sanjay
ATHN 16, NCT04647227: SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

Recruiting
4
55
US
coagulation factor VIIa [recombinant]-jncw, SEVENFACT
American Thrombosis and Hemostasis Network, LFB USA, Inc.
Hemophilia A With Inhibitor, Hemophilia B With Inhibitor
09/26
03/27
KEYSTONE 1, NCT06297486: Study of a Gene Therapy Treatment for Hemophilia A

Withdrawn
3
85
US
SPK-8011, AAV-Spark200-BDD-hFVIII, Dirloctocogene samoparvovec
Spark Therapeutics, Inc.
Hemophilia A
05/27
09/35
NCT02932618 / 2016-001477-33: A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)

Recruiting
3
34
Europe, US, RoW
von Willebrand factor (Recombinant), VONVENDI, rVWF, BAX111, BAX 111, Antihemophilic Factor (Recombinant), ADVATE, Recombinant Factor VIII, rFVIII
Baxalta now part of Shire, Takeda Development Center Americas, Inc.
Von Willebrand Disease
01/25
01/25
NCT05904210: Retrospective Experience Assessing the Real-World Utilization and Effectiveness of SEVENFACT®

Completed
N/A
17
US
SEVENFACT®
Laboratoire français de Fractionnement et de Biotechnologies
Hemophilia
05/24
05/24
ATHN Transcends, NCT04398628: A Natural History Study of Non-Neoplastic Hematologic Disorders

Recruiting
N/A
3000
US
American Thrombosis and Hemostasis Network, Pfizer, Hemophilia of Georgia, Inc., Genentech, Inc., Hemab Therapeutics, CSL Behring, Sanofi, Novo Nordisk A/S
Hematologic Disorder, Bleeding Disorder, Connective Tissue Disorder, Hemophilia, Thrombosis, Von Willebrand Diseases, Thrombophilia, Rare Bleeding Disorder, Platelet Disorder, Factor IX Deficiency, Factor VIII Deficiency, Thalassemia, Sickle Cell Disease
06/35
12/35
Shishehbor, Mehdi
R2P Registry, NCT04371861: Observational Study to Assess Transradial Access for Treatment in the Lower Extremities.

Completed
N/A
120
US
Peripheral Artery Treatment
Terumo Medical Corporation
Peripheral Arterial Disease
08/21
06/22
NCT03970538: PROMISE II: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

Active, not recruiting
N/A
105
US
LimFlow System
LimFlow, Inc.
Critical Limb Ischemia, Critical Lower Limb Ischemia, Peripheral Artery Disease, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Arterial Occlusive Diseases, Arterial Occlusion, Arterial Disease, Peripheral Artery Occlusion, Peripheral Vascular Disease, Peripheral Ischemia, Vascular Diseases
09/22
02/25
iVEST, NCT04748965: Imaging-Guided Vessel Sizing in the Tibial Arteries

Completed
N/A
40
US
Digital Subtraction Angiography
University Hospitals Cleveland Medical Center, Abbott Medical Devices
Peripheral Artery Disease, Critical Limb Ischemia
06/24
06/24
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Recruiting
N/A
1400
Europe, US, RoW
Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation
Medtronic Vascular
Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
11/26
11/29
JETi, NCT04370691: Peripheral Thrombectomy Registry

Active, not recruiting
N/A
260
Europe, Canada, US, RoW
JETi Peripheral Thrombectomy System
Abbott Medical Devices
Peripheral Artery Thrombosis, Peripheral Venous Thrombosis
08/24
08/25
TIC, NCT06544135: Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention

Not yet recruiting
N/A
25
US
FLIR One Pro LT
University Hospitals Cleveland Medical Center
Peripheral Arterial Disease, Critical Limb Ischemia, Critical Lower Limb Ischemia
10/27
10/27
NCT02924857: The Chocolate Touch Study

Active, not recruiting
N/A
333
Europe, US, RoW
Chocolate Touch, Chocolate Touch™ Paclitaxel Coated Balloon Catheter, Lutonix Drug Coated Balloon, LUTONIX® 035 Drug Coated Balloon Catheter
TriReme Medical, LLC
Peripheral Artery Disease (PAD), Ischemia, Intermittent Claudication
06/25
12/26
NCT05313165: PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

Recruiting
N/A
100
US
LimFlow Stent Graft System
LimFlow, Inc.
Critical Limb Ischemia, Chronic Limb-Threatening Ischemia, Peripheral Arterial Disease
05/27
05/27
XLPAD, NCT01904851: Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes

Recruiting
N/A
14000
US
Baylor Research Institute, Boston Scientific Corporation
Peripheral Arterial Disease
01/33
01/33
Milner, Ross
stAAAble, NCT06001918: Nectero EAST System Clinical Study

Recruiting
2/3
400
US
Nectero EAST System
Nectero Medical, Inc.
Abdominal Aortic Aneurysm
03/27
12/29
DISSECT-N, NCT04267055: Post Market Data Collection Registry

Completed
N/A
102
NA
Valiant Navion Thoracic Stent Graft System
Medtronic Cardiovascular, NAMSA
Thoracic Aortic Dissection
06/21
07/24
NCT06586021: Evaluation of the Aortoseal™ for Sealing and Fixation of AAA Endovascular Grafts to Aortic Wall

Recruiting
N/A
25
US
Aortoseal Endostapling System
Endoron Medical
Abdominal Aortic Aneurysm (AAA)
09/29
11/29
GREAT, NCT01658787: Global Registry for Endovascular Aortic Treatment

Active, not recruiting
N/A
4600
Europe, US, RoW
Endovascular aortic repair
W.L.Gore & Associates
Multiple Pathologies
06/27
06/27
Bavaria, Joseph E
MANTRA, NCT05002543: CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

Recruiting
N/A
2150
Europe, Canada, US, RoW
Corcym S.r.l
Cardiac Valve Disease
08/25
12/35
PANTHER, NCT04545502: Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

Recruiting
N/A
2000
Europe, Canada, US
Gelsoft Plus Vascular Graft, Gelsoft Plus, Vascular Bypass Graft, Gelsoft Plus Extra Anatomical, Cardiovascular Patch, Gelseal Patch, Gelsoft Patch, Thinwall Patch, Cardiovascular Fabrics, Gelweave Vascular Graft, Gelweave, Gelweave Valsalva Vascular Graft, Gelweave Valsalva
Vascutek Ltd.
Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection, Carotid Artery Injuries, Aortic Arch, Bypass Extremity Graft, Occlusive Vascular Disease, Aortic Diseases
01/26
01/33
RESILIENCE, NCT03680040: Trial: Evaluation of the Durability of Aortic Bioprostheses/Valves With RESILIA Tissue in Subjects Under 65

Terminated
N/A
110
US
Subjects previously implanted with a RESILIA aortic tissue valve.
Edwards Lifesciences
Aortic Valve Replacement
02/24
02/24
INVIVITY, NCT04902053: INSPIRIS RESILIA Aortic Valve, Valve-in-Valve Surveillance Study

Suspended
N/A
50
US
Subjects previously implanted with INSPIRIS RESILIA Model 11500A and are undergoing planned valve-in-valve treatment.
Edwards Lifesciences
Aortic Valve Replacement
12/30
01/31
EXTEND, NCT05639400: Thoraflex Hybrid and Relay Extension Post-Approval Study

Recruiting
N/A
200
Europe, US
Thoraflex Hybrid, RelayPro NBS
Vascutek Ltd., Bolton Medical
Thoracic Diseases, Aortic Aneurysm, Aortic Dissection, Thoracic Aortic Aneurysm, Thoracic Aortic Dissection
12/35
12/36
Arous, Edward
RESTOR-1, NCT04663867: AngioSafe Peripheral CTO Crossing System Study ( Study)

Completed
N/A
133
US
AngioSafe Peripheral CTO Crossing System
AngioSafe, Inc., Veranex, Inc.
Peripheral Artery Occlusion, Peripheral Arterial Disease
04/23
06/23
NCT05055297: SELUTION4BTK Trial

Recruiting
N/A
376
Europe, US, RoW
SELUTION SLR™ DEB 014, Plain (Uncoated) Balloon Angioplasty (PTA)
MedAlliance, LLC, NAMSA, Cordis Corporation
Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities
06/27
07/29
NCT05132361: SELUTION4SFA Trial

Recruiting
N/A
300
Europe, US, RoW
SELUTION SLR™ 018 DEB, Plain (Uncoated) Balloon Angioplasty (PTA)
MedAlliance, LLC, NAMSA, Cordis Corporation
Peripheral Arterial Disease, Superficial Femoral Artery Stenosis
08/25
12/29
NCT05928221: Post Market Registry Study of the Philips QuickClear Mechanical Thrombectomy System

Recruiting
N/A
50
US
Thrombectomy, QuickClear Mechanical Thrombectomy system
Paul J. Gagne
Acute Deep Venous Thrombosis of Ileofemoral Vein
12/24
03/26
NCT05489588: The GORE® VIAFORT Vascular Stent Iliofemoral Study

Active, not recruiting
N/A
165
US
GORE® VIAFORT Vascular Stent
W.L.Gore & Associates
Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis, Venous Ulcer, Venous Stenosis, Venous Occlusion, Vein Thrombosis, Vein Occlusion, Vein Disease
04/25
04/29
THOR, NCT05916950: The IDE Study

Recruiting
N/A
155
US
Thor laser atherectomy, Thor calcium modification
Philips Clinical & Medical Affairs Global, NAMSA, Massachusetts General Hospital
Peripheral Artery Disease, Peripheral Artery Stenosis, Peripheral Artery Calcification, PAD
10/26
11/27
Gentile, Erica
ADCT-901-101, NCT04972981: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT-901 in Participants With Selected Advanced Solid Tumors

Active, not recruiting
1
132
Europe, US
ADCT-901
ADC Therapeutics S.A.
Advanced Solid Tumors
04/24
04/25
Becerra, Mario A
NCT05469438: IMAS Optimization and Applicability in an Acute Stroke Setting.

Active, not recruiting
N/A
30
US
Case Western Reserve University, Highland Instruments, Inc.
Acute Stroke
08/23
09/25
NCT05811143: Examining the Effects of Dorsal Column Stimulation on Pain From Lumbar Spinal Stenosis Related to Epidural Lipomatosis.

Completed
N/A
3
US
Spinal Cord Stimulator
University Hospitals Cleveland Medical Center
Lipomatosis, Low Back Pain
01/24
01/24
RESTORE, NCT04803214: ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation

Active, not recruiting
N/A
203
US
ReActiv8
Mainstay Medical
Chronic Low-back Pain
09/24
01/26
Sesaba, Kassaye
stAAAble, NCT06001918: Nectero EAST System Clinical Study

Recruiting
2/3
400
US
Nectero EAST System
Nectero Medical, Inc.
Abdominal Aortic Aneurysm
03/27
12/29
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Recruiting
N/A
1400
Europe, US, RoW
Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation
Medtronic Vascular
Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
11/26
11/29
REVIT, NCT06394739: RevCore for In Stent Thrombosis

Recruiting
N/A
100
US
Thrombectomy, RevCore Thrombectomy
Inari Medical
In-stent Thrombosis
12/25
12/26
NCT05409976: The GORE® VIAFORT Vascular Stent IVC Study

Active, not recruiting
N/A
111
Europe, US, RoW
GORE® VIAFORT Vascular Stent
W.L.Gore & Associates
Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis, Venous Ulcer, Venous Stenosis, Venous Occlusion, Vein Thrombosis, Vein Occlusion, Vein Disease
01/25
01/29
NCT05489588: The GORE® VIAFORT Vascular Stent Iliofemoral Study

Active, not recruiting
N/A
165
US
GORE® VIAFORT Vascular Stent
W.L.Gore & Associates
Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis, Venous Ulcer, Venous Stenosis, Venous Occlusion, Vein Thrombosis, Vein Occlusion, Vein Disease
04/25
04/29
ROADSTER 3, NCT05365490: Post-approval Study of Transcarotid Artery Revascularization in Standard Risk Patients with Significant Carotid Artery Disease

Active, not recruiting
N/A
344
US
Transcarotid Artery Revascularization (TCAR), Carotid Revascularization, Carotid Artery Stenting
Silk Road Medical
Carotid Artery Diseases
09/25
09/25
JAGUAR, NCT05064540: Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

Recruiting
N/A
450
US
Alto Abdominal Stent Graft System, FDA Approved EVAR AAA Graft Systems
Endologix
AAA, AAA - Abdominal Aortic Aneurysm
12/28
12/28
Casey, Terri
INHALE-1, NCT04974528: Afrezza® Study in Pediatrics

Active, not recruiting
3
319
US
Afrezza, Technosphere Insulin, Rapid-acting Insulin Analog, insulin aspart, insulin lispro, insulin glulisine, Novolog®, Fiasp®, Humalog®, Admelog®, Apidra®, Basal Insulin, insulin glargine, insulin degludec, insulin detemir, Lantus®, Abasaglar®, Basaglar®, Semglee®, Toujeo®, Tresiba®, Levemir®
Mannkind Corporation, Jaeb Center for Health Research
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
10/24
05/25
NCT05714059: Safety and Effectiveness of the MiniMed™ 780G System With DS5 CGM

Completed
N/A
250
US
Insulin Pump with Continuous Glucose Monitoring
Medtronic Diabetes
Type 1 Diabetes
12/23
12/23
SUCCEED2, NCT06604871: Safety Evaluation of MiniMed™ 780G System with DS5 CGM in Children

Recruiting
N/A
60
US
Insulin Pump with Continuous Glucose Monitoring
Medtronic Diabetes
Type 1 Diabetes
06/25
06/25
NCT06074458: GO TEAM: Glucose Optimization Through Technology Assisted Management

Recruiting
N/A
60
US
Glucosano, Community Health Worker diabetes technology coach
Sarah MacLeish, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), KeborMed
Type 1 Diabetes
10/26
10/26
Herz, Katrina
SRF388-201, NCT05359861: Trial of Atezolizumab and Bevacizumab With SRF388 or Placebo in Patients With Hepatocellular Carcinoma

Active, not recruiting
2
134
US, RoW
SRF388, Atezolizumab, Tecentriq, Bevacizumab, Avastin, Placebo
Coherus Biosciences, Inc.
Hepatocellular Carcinoma
05/25
05/26
Indapta-Trial-1, NCT06119685: IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

Recruiting
1/2
128
US
IDP-023, Rituximab, Rituxan, Daratumumab, Darzalex, Interleukin-2, Proleukin, Cyclophosphamide, Fludarabine, Mesna
Indapta Therapeutics, INC.
NHL, Multiple Myeloma, Blood Cancer, Refractory Non-Hodgkin Lymphoma, Relapsed Non-Hodgkin Lymphoma, Refractory Multiple Myeloma, Relapsed Multiple Myeloma
12/25
12/29
MK-6482-030, NCT06234605: A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

Recruiting
1
80
US
HC-7366, Belzutifan, WELIREG™, MK-6482
HiberCell, Inc., Merck Sharp & Dohme LLC
Renal Cell Carcinoma
11/26
11/27
WUN101-01, NCT05470140: A Phase 1 Study of WU-NK-101 in Patients With Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML)

Active, not recruiting
1
9
US, RoW
WU-NK-101
Wugen, Inc.
Acute Myeloid Leukemia
10/24
01/25
Baeza, Christian
MANTRA, NCT05002543: CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

Recruiting
N/A
2150
Europe, Canada, US, RoW
Corcym S.r.l
Cardiac Valve Disease
08/25
12/35
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
N/A
1056
Europe, Canada, US
Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Medtronic Cardiovascular
Mitral Valve Regurgitation
10/26
09/36
Bonatti, Johannes
MIST, NCT03447938: The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial

Recruiting
N/A
176
Europe, Canada, Japan, US, RoW
MICS CABG, Minimally invasive coronary artery bypass grafting, Conventional CABG, coronary artery bypass grafting via sternotomy
Ottawa Heart Institute Research Corporation, London Health Sciences Centre, Heart Center Leipzig - University Hospital, Fortis Escorts Heart Institute, The Methodist Hospital Research Institute, Carolinas Medical Center, Gundersen Lutheran Health System, Jilin Heart Hospital, Far Eastern Memorial Hospital, Medtronic, Apollo Hospitals Enterprise Limited, Fresno Heart and Surgical Hospital, Ichinomiya-Nishi Hospital
Coronary Artery Disease
03/26
03/28
NCT04073420: Medtronic Cardiac Surgery PMCF Registry

Recruiting
N/A
2700
Europe, US
Surgical Heart Valve Repair Products, Surgical Heart Valve Replacement Products
Medtronic Cardiac Surgery
Valve Disease, Heart
12/39
12/39
Reynolds, Kyle
FORWARD PAD, NCT05858905: IDE Study With the Shockwave Mini S IVL Catheter

Active, not recruiting
N/A
75
US
Intravascular Lithotripsy
Shockwave Medical, Inc.
Peripheral Arterial Disease
04/24
04/25
REVIT, NCT06394739: RevCore for In Stent Thrombosis

Recruiting
N/A
100
US
Thrombectomy, RevCore Thrombectomy
Inari Medical
In-stent Thrombosis
12/25
12/26
NCT05409976: The GORE® VIAFORT Vascular Stent IVC Study

Active, not recruiting
N/A
111
Europe, US, RoW
GORE® VIAFORT Vascular Stent
W.L.Gore & Associates
Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis, Venous Ulcer, Venous Stenosis, Venous Occlusion, Vein Thrombosis, Vein Occlusion, Vein Disease
01/25
01/29
NCT05489588: The GORE® VIAFORT Vascular Stent Iliofemoral Study

Active, not recruiting
N/A
165
US
GORE® VIAFORT Vascular Stent
W.L.Gore & Associates
Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis, Venous Ulcer, Venous Stenosis, Venous Occlusion, Vein Thrombosis, Vein Occlusion, Vein Disease
04/25
04/29
Zacharias, Nikolaos
stAAAble, NCT06001918: Nectero EAST System Clinical Study

Recruiting
2/3
400
US
Nectero EAST System
Nectero Medical, Inc.
Abdominal Aortic Aneurysm
03/27
12/29
NCT05489588: The GORE® VIAFORT Vascular Stent Iliofemoral Study

Active, not recruiting
N/A
165
US
GORE® VIAFORT Vascular Stent
W.L.Gore & Associates
Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis, Venous Ulcer, Venous Stenosis, Venous Occlusion, Vein Thrombosis, Vein Occlusion, Vein Disease
04/25
04/29
Nuzzolo, Kathryn
stAAAble, NCT06001918: Nectero EAST System Clinical Study

Recruiting
2/3
400
US
Nectero EAST System
Nectero Medical, Inc.
Abdominal Aortic Aneurysm
03/27
12/29
 

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