The Brigham and Women's Hospital
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 10 Trials 
24 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Bhasin, Shalender
NCT05038488: Phase 2a MIB-626 vs. Placebo COVID-19

Completed
2
42
US
MIB-626, NAD-boosting drug, Placebo, Home Treatment
Metro International Biotech, LLC
Covid19, Stage 1 Acute Kidney Injury
08/23
08/23
NCT03716739: Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency

Active, not recruiting
2
137
US
Testosterone Cypionate 100 MG/ML, Depo-Testosterone, Placebo, Inactive comparator
Dana-Farber Cancer Institute, National Institute on Aging (NIA)
Prostate Cancer
09/25
03/26
NCT03576001: Multimodality Intervention for Function and Metabolism in SCI

Active, not recruiting
2
84
US
Testosterone Undecanoate, hybrid exercise
Brigham and Women's Hospital, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Spaulding Rehabilitation Hospital
Spinal Cord Injuries
01/25
06/25
NCT05878119: Effects of MIB-626 With and Without A High-Intensity Multi-Dimensional Exercise Training Program

Recruiting
2
120
US
Investigational Product - MIB 626, Investigational Product, Placebo, Standardized, progressive, high intensity, multidimensional exercise, Usual Physical Activity, Usual Physical Acitivty
Metro International Biotech, LLC
Healthy
04/25
06/25
DKD, NCT05759468: NAD Augmentation in Diabetes Kidney Disease

Recruiting
2
140
US
Investigational Product - MIB 626, NMN, Placebo, Placebo for NMN
Brigham and Women's Hospital, Boston Medical Center
Type2diabetes, Diabetic Kidney Disease
12/25
07/26
NCT05040321: Sirtuin-NAD Activator in Alzheimer's Disease

Recruiting
1/2
50
US
MIB-626, Placebo
Brigham and Women's Hospital
Alzheimer's Disease (Incl Subtypes), Dementia
04/24
12/24
NCT04772820: Feasibility of Remote Home Support Coaches (SOCIAL Study)

Completed
N/A
10
US
Telephone-based coaching, Remote coaching
Brigham and Women's Hospital, University of Maryland, Baltimore, National Institute on Aging (NIA)
Malnutrition, Isolation, Depression, Anxiety, Sedentary Behavior, Loneliness
06/22
11/22
Fisher, Naomi D
NCT05211648: COOL-BP Study: Continuous Versus Occasional Blood Pressure Study

Completed
N/A
55
US
Aktiia Bracelet
Aktiia SA
Hypertension
05/23
05/23
US GPS, NCT06297291: Global Paradise System US Post Approval Study

Recruiting
N/A
1000
US
Paradise Ultrasound Renal Denervation Treatment, Paradise Ultrasound RDN
ReCor Medical, Inc.
Hypertension, Cardiovascular Diseases, Vascular Diseases
09/26
07/31
TRIO CAP, NCT05017935: RADIANCE Continued Access Protocol

Active, not recruiting
N/A
300
US
Renal Denervation
ReCor Medical, Inc.
Hypertension, Hypertension, Resistant to Conventional Therapy, Vascular Diseases, Cardiovascular Diseases
12/28
12/28
Sang, Christine N
NCT04087941: Efficacy and Safety of VM202 in Painful Diabetic Peripheral Neuropathy -The HOPES Trial

Not yet recruiting
2
50
US
VM-202
Brigham and Women's Hospital
Painful Diabetic Neuropathy
12/22
12/22
CYPRESS, NCT05895552: A Phase 2 Study of RTA 901 (BIIB143) in Participants With Diabetic Peripheral Neuropathic Pain

Recruiting
2
384
US
RTA 901, BIIB143, Cemdomespib, RTA 901-Matching Placebo
Reata, a wholly owned subsidiary of Biogen
Diabetic Peripheral Neuropathic Pain
08/26
08/26
Ross, Edgar L
ASPIRE PH, NCT04555161: Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System

Recruiting
N/A
30
US
Aria CV Pulmonary Hypertension System, Aria CV PH System
Aria CV, Inc
Pulmonary Arterial Hypertension, Pulmonary Hypertension, Right Heart Dysfunction
10/25
10/26
Bhasin, Shalendar
NCT05038488: Phase 2a MIB-626 vs. Placebo COVID-19

Completed
2
42
US
MIB-626, NAD-boosting drug, Placebo, Home Treatment
Metro International Biotech, LLC
Covid19, Stage 1 Acute Kidney Injury
08/23
08/23
NCT05040321: Sirtuin-NAD Activator in Alzheimer's Disease

Recruiting
1/2
50
US
MIB-626, Placebo
Brigham and Women's Hospital
Alzheimer's Disease (Incl Subtypes), Dementia
04/24
12/24
Smith, Alexander
REPAC, NCT06017037: REward Processing And Citalopram Study

Recruiting
1/2
40
Europe
Citalopram 20mg, Placebo
University of Oxford
Anhedonia
05/24
05/24
Roberson, Marti
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis

Active, not recruiting
N/A
270
Europe, US
RheOx Bronchial Rheoplasty, Sham Procedure
Gala Therapeutics, Inc.
Chronic Bronchitis
05/24
10/25
COSIRA-II, NCT05102019: Efficacy of the COronary SInus Reducer in Patients with Refractory Angina II

Recruiting
N/A
380
Canada, US
Arm 1: treatment with Neovasc Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry
Neovasc Inc., Shockwave Medical, Inc.
Refractory Angina
06/25
12/28
US GPS, NCT06297291: Global Paradise System US Post Approval Study

Recruiting
N/A
1000
US
Paradise Ultrasound Renal Denervation Treatment, Paradise Ultrasound RDN
ReCor Medical, Inc.
Hypertension, Cardiovascular Diseases, Vascular Diseases
09/26
07/31
NCT05313165: PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

Recruiting
N/A
100
US
LimFlow Stent Graft System
LimFlow, Inc.
Critical Limb Ischemia, Chronic Limb-Threatening Ischemia, Peripheral Arterial Disease
05/27
05/27
TRIO CAP, NCT05017935: RADIANCE Continued Access Protocol

Active, not recruiting
N/A
300
US
Renal Denervation
ReCor Medical, Inc.
Hypertension, Hypertension, Resistant to Conventional Therapy, Vascular Diseases, Cardiovascular Diseases
12/28
12/28
Halliday, Ian
TRIO CAP, NCT05017935: RADIANCE Continued Access Protocol

Active, not recruiting
N/A
300
US
Renal Denervation
ReCor Medical, Inc.
Hypertension, Hypertension, Resistant to Conventional Therapy, Vascular Diseases, Cardiovascular Diseases
12/28
12/28
Hussain, M
ACCESS2, NCT05425056: A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery

Active, not recruiting
3
136
Europe, US
Sirolimus, Sirolimus-eluting Collagen Implant, SeCI, Sirogen
Vascular Therapies, Inc.
Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD, Chronic Kidney Failure, Complication of Hemodialysis, Vascular Access Complication, Arteriovenous Fistula
03/25
08/25
Mccracken, S
ACCESS2, NCT05425056: A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery

Active, not recruiting
3
136
Europe, US
Sirolimus, Sirolimus-eluting Collagen Implant, SeCI, Sirogen
Vascular Therapies, Inc.
Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD, Chronic Kidney Failure, Complication of Hemodialysis, Vascular Access Complication, Arteriovenous Fistula
03/25
08/25

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