University of California Davis MIND Institute
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 11 Trials 
25 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Handen, Benjamin L
DS+ADHD Pilot, NCT04219280: Evaluating Treatment of ADHD in Children with Down Syndrome

Recruiting
4
100
US
Quillivant XR, Placebo
Children's Hospital Medical Center, Cincinnati, University of California, Davis, University of Pittsburgh Medical Center, Boston Children's Hospital, Boston, MA, USA
Down Syndrome, ADHD
09/25
09/25
NCT05916339: AWARE: Management of ADHD in Autism Spectrum Disorder

Recruiting
4
500
Canada, US
Randomization to either Amphetamine (AMP) class of stimulant medication or Methylphenidate (MPH) class of stimulant medication, Randomization to either Alpha 2 agonist class of medication or alternate class of stimulant.
Daniel Coury, Patient-Centered Outcomes Research Institute, University of California, Irvine, Holland Bloorview Kids Rehabilitation Hospital, Children's Hospital of Philadelphia, University of Rochester Golisano Children's Hospital, Nationwide Children's Hospital, Children's Hospital Medical Center, Cincinnati, University of Pittsburgh, Children's Hospital Los Angeles, University of Virginia, University of Alberta, Massachusetts General Hospital, MaineHealth, University of Michigan
ADHD, Autism Spectrum Disorder
01/27
12/27
NCT05418023: Validation of a Salivary miRNA Diagnostic Test for ASD

Recruiting
N/A
6604
US
Salivary Collection, Adaptive Assessment, Medical and Demographic questionnaire, Autism Assessment, Intellectual Development Assessment
Quadrant Biosciences Inc., University of California, Irvine, Holland Bloorview Kids Rehabilitation Hospital, Children's Hospital of Philadelphia, MetroHealth Medical Center, University of Rochester, Nationwide Children's Hospital, Children's Hospital Medical Center, Cincinnati, University of Pittsburgh, University of Massachusetts, Worcester, Children's Hospital Los Angeles, Prisma Health-Upstate, University of Virginia, State University of New York - Upstate Medical University, Rush University, Seattle Children's Hospital, Drexel University, Emory University
Autism Spectrum Disorder, Developmental Delay
07/23
07/23
CST, NCT06038799: Caregiver Skills Training: Comparing Clinician Training Methods

Recruiting
N/A
35
US
Caregiver Skills Training (CST)
University of Pittsburgh, Autism Speaks
Parenting
12/24
12/24
TRC-DS, NCT04165109: Trial-Ready Cohort-Down Syndrome

Recruiting
N/A
450
Europe, US
Flutafuranol, [18F]NAV4694, NAV4694, Pittsburgh Compound (PIB), [11C]-PIB, PIB, MK6240, [18F]MK-6240
University of Southern California, National Institute on Aging (NIA), Alzheimer's Clinical Trials Consortium, Alzheimer's Therapeutic Research Institute
Down Syndrome, Alzheimer Disease, Dementia
12/25
12/25
Schweitzer, Julie
DelTA, NCT03457402: Shaping Tolerance for Delayed Rewards

Recruiting
N/A
50
US
Shaping Delay Tolerance
University of California, Davis, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Impulsivity
05/25
05/26
NCT04526600: Fidgeting and Attentional and Emotional Regulation in ADHD

Recruiting
N/A
109
US
Fidget ball
University of California, Davis
ADHD
07/24
07/25
VRAM, NCT03221244: Virtual Reality Attention Management

Recruiting
N/A
50
US
VR Treatment, VR Active Control
University of California, Davis, National Institute of Mental Health (NIMH)
ADHD
09/26
07/27
Angkustsiri, Kathleen
DS+ADHD Pilot, NCT04219280: Evaluating Treatment of ADHD in Children with Down Syndrome

Recruiting
4
100
US
Quillivant XR, Placebo
Children's Hospital Medical Center, Cincinnati, University of California, Davis, University of Pittsburgh Medical Center, Boston Children's Hospital, Boston, MA, USA
Down Syndrome, ADHD
09/25
09/25
Froehlich, Tanya E
NCT03781752: Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD

Recruiting
4
500
US
Methylphenidate, d,l-methylphenidate, MPH
Icahn School of Medicine at Mount Sinai, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), University of Florida, Children's Hospital Medical Center, Cincinnati, Seattle Children's Hospital
ADHD, Attention Deficit Hyperactivity Disorder
08/25
08/25
DS+ADHD Pilot, NCT04219280: Evaluating Treatment of ADHD in Children with Down Syndrome

Recruiting
4
100
US
Quillivant XR, Placebo
Children's Hospital Medical Center, Cincinnati, University of California, Davis, University of Pittsburgh Medical Center, Boston Children's Hospital, Boston, MA, USA
Down Syndrome, ADHD
09/25
09/25
HYP01, NCT06042257: Guanfacine for Hyperactivity in Children with Down Syndrome (HYPEbeGONE_DS)

Recruiting
2
60
US
Guanfacine Hydrochloride Immediate Release, Placebo
Rachel G. Greenberg, MD, MB, MHS, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hyperactivity in Children with Down Syndrome, Impulsivity in Children with Down Syndrome
11/25
02/26
APCSAHAODBO, NCT04017286: Relationship About Pregnancy Health and Offspring Developmental &Behavioral Outcomes

Recruiting
N/A
3000
RoW
Chen Li
Children Behavior Problem, Pregnancy
07/25
12/28
Esbensen, Anna
DS+ADHD Pilot, NCT04219280: Evaluating Treatment of ADHD in Children with Down Syndrome

Recruiting
4
100
US
Quillivant XR, Placebo
Children's Hospital Medical Center, Cincinnati, University of California, Davis, University of Pittsburgh Medical Center, Boston Children's Hospital, Boston, MA, USA
Down Syndrome, ADHD
09/25
09/25
HYP01, NCT06042257: Guanfacine for Hyperactivity in Children with Down Syndrome (HYPEbeGONE_DS)

Recruiting
2
60
US
Guanfacine Hydrochloride Immediate Release, Placebo
Rachel G. Greenberg, MD, MB, MHS, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hyperactivity in Children with Down Syndrome, Impulsivity in Children with Down Syndrome
11/25
02/26
ECODS-2, NCT04208685: Evaluating Cognitive Outcomes in Down Syndrome

Active, not recruiting
N/A
202
US
Children's Hospital Medical Center, Cincinnati, Colorado State University
Down Syndrome
06/24
06/26
LIFE-DSR, NCT04149197: Down Syndrome Clinical Trials - Study of Alzheimer's Disease in Down Syndrome

Terminated
N/A
252
US
LuMind IDSC Foundation, Alzheimer's Disease Cooperative Study (ADCS)
Alzheimer's Disease in Down Syndrome
04/24
04/24
POPS or POP02, NCT04278404: Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Recruiting
N/A
5000
Canada, US
The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:, Aminocaproic acid, Amiodarone, Bosentan, Budesonide, Cefdinir, Cefepime, Ceftazidime, Clindamycin, Clobazam, Dexamethasone, Dexmedetomidine, Dextroamphetamine/Amphetamine, Fosfomycin, Furosemide, Gabapentin, Guanfacine, Hydrocortisone, Labetalol, Meropenem, Metformin, Milrinone, Nalbuphine, Nicardipine, Nifedipine, Oseltamivir, Oxycodone, Risperidone, Sertraline, Sevelamer Carbonate / Sevelamer Hydrochloride, Spironolactone, Terbutaline, Tranexamic acid, Voriconazole, Zolpidem, Azithromycin, Lopinavir/Ritonavir, Ribavirin, Tocilizumab, Anakinra, Aspirin, Canakinumab, Colchicine, Interferon, Remdesivir, Ruxolitinib, Sarilumab, Abatacept, Infliximab
Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
09/26
09/27
Abbeduto, Leonard
DS+ADHD Pilot, NCT04219280: Evaluating Treatment of ADHD in Children with Down Syndrome

Recruiting
4
100
US
Quillivant XR, Placebo
Children's Hospital Medical Center, Cincinnati, University of California, Davis, University of Pittsburgh Medical Center, Boston Children's Hospital, Boston, MA, USA
Down Syndrome, ADHD
09/25
09/25
Harris, Danielle
NCT04921943: Hypertonic Saline for MAC

Recruiting
4
50
Canada, US
Hypertonic saline, Azithromycin, Ethambutol, Rifampin
Oregon Health and Science University, NTM Info & Research, Inc., University Health Network, Toronto, New York University
Nontuberculous Mycobacterial Lung Disease, Nontuberculous Mycobacterium Infection
06/25
06/25
Ponzini, Danielle
DS+ADHD Pilot, NCT04219280: Evaluating Treatment of ADHD in Children with Down Syndrome

Recruiting
4
100
US
Quillivant XR, Placebo
Children's Hospital Medical Center, Cincinnati, University of California, Davis, University of Pittsburgh Medical Center, Boston Children's Hospital, Boston, MA, USA
Down Syndrome, ADHD
09/25
09/25
Canty, Marie
DS+ADHD Pilot, NCT04219280: Evaluating Treatment of ADHD in Children with Down Syndrome

Recruiting
4
100
US
Quillivant XR, Placebo
Children's Hospital Medical Center, Cincinnati, University of California, Davis, University of Pittsburgh Medical Center, Boston Children's Hospital, Boston, MA, USA
Down Syndrome, ADHD
09/25
09/25
HYP01, NCT06042257: Guanfacine for Hyperactivity in Children with Down Syndrome (HYPEbeGONE_DS)

Recruiting
2
60
US
Guanfacine Hydrochloride Immediate Release, Placebo
Rachel G. Greenberg, MD, MB, MHS, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hyperactivity in Children with Down Syndrome, Impulsivity in Children with Down Syndrome
11/25
02/26
Sargado, Sabrina
DS+ADHD Pilot, NCT04219280: Evaluating Treatment of ADHD in Children with Down Syndrome

Recruiting
4
100
US
Quillivant XR, Placebo
Children's Hospital Medical Center, Cincinnati, University of California, Davis, University of Pittsburgh Medical Center, Boston Children's Hospital, Boston, MA, USA
Down Syndrome, ADHD
09/25
09/25
HYP01, NCT06042257: Guanfacine for Hyperactivity in Children with Down Syndrome (HYPEbeGONE_DS)

Recruiting
2
60
US
Guanfacine Hydrochloride Immediate Release, Placebo
Rachel G. Greenberg, MD, MB, MHS, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hyperactivity in Children with Down Syndrome, Impulsivity in Children with Down Syndrome
11/25
02/26

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