| Koblizek, Vladimir |
INFURO, NCT06252454: The Impact of Inhaled Furosemide and Perorally Administered Levodropropizine on Dyspnea in Patients With Respiratory Diseases |
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| Recruiting | 2/3 | 102 | RoW | Furosemide 40 mg, Levodropropizine, Levopront, Placebo - saline | University Hospital Hradec Kralove, Masaryk University | Dyspnea | 12/24 | 12/25 | | |
LUCAS, NCT04228237: LUng CAncer focuS - Long-term Monitoring of Bronchogenic Carcinoma Patients |
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| Recruiting | N/A | 2300 | RoW | | Ceska Lekarska Spolecnost Jana Evangelisty Purkyne z.s., OAKS Consulting s.r.o. | Lung Cancer | 05/25 | 05/25 | | |
| Belohlavkova, Petra |
| Active, not recruiting | 3 | 430 | Europe, Canada, US, RoW | Pelabresib, Ruxolitinib, Placebo | Constellation Pharmaceuticals | Myelofibrosis, Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis | 08/23 | 12/27 | | |
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HALF, NCT04147533: Efficacy and Safety of TKIs' Withdrawal After a Two-step Dose Reduction in Patients with Chronic Myeloid Leukemia |
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| Active, not recruiting | 2 | 150 | RoW | Imatinib withdrawal, Glivec withdrawal, Dasatinib, Sprycel withdrawal, Nilotinib, Tasigna withdrawal | Masaryk University | Chronic Myeloid Leukemia, Chronic Phase, Withdrawal;Drug | 06/26 | 06/26 | | |
| Dostal, Pavel |
NCT03644641: The Influence of Prone Position for Spinal Surgery on Visual Acuity |
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| Not yet recruiting | N/A | 60 | RoW | Desflurane Group, Propofol Group | University Hospital Hradec Kralove | Vision; Disorder, Loss | 11/28 | 12/29 | | |
NCT04114799: Haemodynamical Optimization During Brain Surgery |
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| Recruiting | N/A | 50 | RoW | Hemodynamic management based on invasive fluid responsiveness parameters, Hemodynamic management based on noninvasive cardiac output and SVV measurement | University Hospital Hradec Kralove | Brain Edema | 04/25 | 11/26 | | |
NCT04887623: Dynamics of Markers of Infection and Inflammation in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients |
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| Recruiting | N/A | 30 | RoW | | University Hospital Hradec Kralove | COVID-19 Respiratory Infection | 07/25 | 08/26 | | |
NCT04311840: Impact of Nimodipine on Sublingual Microcirculation in Patients With Hemorrhage - a Prospective Monocentric Observational Study |
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| Recruiting | N/A | 30 | RoW | | University Hospital Hradec Kralove | Subarachnoid Hemorrhage | 10/22 | 12/22 | | |
NCT03476213: Manual Versus Targer-controll Infusion in Reduction of Awareness and Dreaming |
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| Recruiting | N/A | 80 | RoW | Group TCI, Group TIVA | University Hospital Hradec Kralove | Anesthesia Awareness | 12/25 | 06/27 | | |
| Tomas, Suchy |
NCT03644641: The Influence of Prone Position for Spinal Surgery on Visual Acuity |
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| Not yet recruiting | N/A | 60 | RoW | Desflurane Group, Propofol Group | University Hospital Hradec Kralove | Vision; Disorder, Loss | 11/28 | 12/29 | | |
NCT03476213: Manual Versus Targer-controll Infusion in Reduction of Awareness and Dreaming |
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| Recruiting | N/A | 80 | RoW | Group TCI, Group TIVA | University Hospital Hradec Kralove | Anesthesia Awareness | 12/25 | 06/27 | | |
| Palicka, Vladimir |
NCT04887623: Dynamics of Markers of Infection and Inflammation in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients |
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| Recruiting | N/A | 30 | RoW | | University Hospital Hradec Kralove | COVID-19 Respiratory Infection | 07/25 | 08/26 | | |
| Vojacek, Jan |
AKITA, NCT05126303: Efficacy and Safety of RMC-035 in Subjects at High Risk for Acute Kidney Injury Following Open-Chest Cardiac Surgery |
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| Terminated | 2 | 177 | Europe, Canada, US, RoW | RMC-035, ROSgard, Placebo | Guard Therapeutics AB | Acute Kidney Injury | 04/23 | 07/23 | | |
| Recruiting | N/A | 60 | RoW | Blood sample test, Thoracic Aortic Surgery | University Hospital Hradec Kralove, American Association for Thoracic Surgery | Systemic Inflammatory Response Syndrome, Infections, Thoracic Aortic Aneurysm, Aortic Diseases, Immunological Abnormality | 06/24 | 06/24 | | |
NCT04124120: Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women |
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| Recruiting | N/A | 2000 | Europe, Canada, Japan, US, RoW | Single arterial graft, Multiple arterial grafting | Weill Medical College of Cornell University, New York Presbyterian Hospital, Sunnybrook Health Sciences Centre, Cedars-Sinai Medical Center, Columbia University, Duke University | Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting | 03/30 | 03/30 | | |
| Burkert, Jan |
AKITA, NCT05126303: Efficacy and Safety of RMC-035 in Subjects at High Risk for Acute Kidney Injury Following Open-Chest Cardiac Surgery |
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| Terminated | 2 | 177 | Europe, Canada, US, RoW | RMC-035, ROSgard, Placebo | Guard Therapeutics AB | Acute Kidney Injury | 04/23 | 07/23 | | |
POINTER, NCT06475274: A Phase 2b Dose Finding Study of RMC-035 in Participants Undergoing Open-chest Cardiac Surgery |
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| Recruiting | 2 | 161 | Europe, Canada | RMC-035, Placebo | Guard Therapeutics AB | Kidney Injury Following Open-Chest Cardiac Surgery | 10/25 | 10/25 | | |
| Widener, Nancy |
| Recruiting | 3 | 1655 | Europe, Canada, Japan, US, RoW | Abelacimab, MAA868, Apixaban, Eliquis | Anthos Therapeutics, Inc., Itreas | Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism | 12/26 | 02/27 | | |
| Recruiting | 3 | 1020 | Europe, Canada, US, RoW | Abelacimab, MAA868, Dalteparin, Fragmin | Anthos Therapeutics, Inc., Itreas | Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism | 12/26 | 02/27 | | |
| Sykorova, Alice |
| Recruiting | N/A | 500 | RoW | | Interni hematologicka klinika FNKV, Charles University, Czech Republic, General University Hospital, Prague, University Hospital Olomouc, University Hospital Hradec Kralove, University Hospital, Motol | Prognostic Cancer Model | 12/23 | 12/27 | | |
| PaÅ™Ãzková, Renata ÄŒerná |
| Completed | N/A | 3000 | RoW | Vaccionation eighter started or full course | University Hospital Hradec Kralove | COVID-19, Vaccination, Immunity, Respiratory Failure | 11/23 | 11/23 | | |
| Astapenko, David |
NCT05606536: The Impact of Intra-operative Fluid Infusion Rate on Microcirculation |
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| Recruiting | N/A | 80 | RoW | Crystalloid Solutions | University Hospital Hradec Kralove | Fluid Therapy, Microcirculation, Hemodilution | 12/24 | 12/24 | | |
NCT05609123: Endothelial Glycocalyx Damage in Brain Death Organ Donors |
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| Recruiting | N/A | 100 | RoW | Endothelial glycocalyx damage assessment | University Hospital Hradec Kralove | Brain Damage Due to Hypoxia, Organ Donors, Organ Transplant Failure or Rejection | 12/24 | 12/24 | | |
| Sirak, Igor |
| Recruiting | N/A | 2000 | Europe, RoW | | European Organisation for Research and Treatment of Cancer - EORTC | Cancer | 04/26 | 04/26 | | |
| Myjavec, Andrej |
POINTER, NCT06475274: A Phase 2b Dose Finding Study of RMC-035 in Participants Undergoing Open-chest Cardiac Surgery |
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| Recruiting | 2 | 161 | Europe, Canada | RMC-035, Placebo | Guard Therapeutics AB | Kidney Injury Following Open-Chest Cardiac Surgery | 10/25 | 10/25 | | |
| Recruiting | N/A | 60 | RoW | Blood sample test, Thoracic Aortic Surgery | University Hospital Hradec Kralove, American Association for Thoracic Surgery | Systemic Inflammatory Response Syndrome, Infections, Thoracic Aortic Aneurysm, Aortic Diseases, Immunological Abnormality | 06/24 | 06/24 | | |
