Toronto Liver Centre
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 7 Trials 
17 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
PI
OASIS, NCT04986995: OpicApone Sleep dISorder

Active, not recruiting
4
22
Europe
Opicapone, BIA 9-1067
Bial - Portela C S.A.
Parkinson Disease
06/23
06/23
ADESOS, NCT05469464 / 2021-006707-15: Study to Assess the Efficacy and Safety of Orismilast in Atopic Dermatitis

Active, not recruiting
2b
210
Europe, US
Orismilast modified release tablets, Placebo
UNION therapeutics
Atopic Dermatitis, Skin Diseases
01/24
02/24
NCT04684914 / 2020-002118-42: HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB)

Terminated
2
87
Europe, Canada, US
HepTcell, Placebo
Altimmune, Inc., Altimmune, Inc
Hepatitis B, Chronic
03/24
04/24
NCT05686239: A Study to Evaluate RL-007 in the Treatment of Cognitive Impairment Associated With Schizophrenia (CIAS)

Recruiting
2
234
Europe, US, RoW
RL-007, Placebo
Recognify Life Sciences
Cognitive Impairment Associated With Schizophrenia (CIAS), Cognitive Impairment, Schizophrenia
06/25
07/25
NCT06040346: Open-Label Study to Assess Meplazumab in Adult Patients Diagnosed with Plasmodium Falciparum

Active, not recruiting
2
60
RoW
Meplazumab for Injection
Jiangsu Pacific Meinuoke Bio Pharmaceutical Co Ltd
Malaria
08/25
10/25
TRAK-ER, NCT04985266 / 2020-004022-36: A Trial of Early Detection of Molecular Relapse With Circulating Tumour DNA Tracking and Treatment With Palbociclib Plus Fulvestrant Versus Standard Endocrine Therapy in Patients With ER Positive HER2 Negative Breast Cancer

Recruiting
2
1100
Europe
Palbociclib 125Mg Tab, Fulvestrant injection, Tamoxifen, Letrozole, Exemestane, Anastrozole
Royal Marsden NHS Foundation Trust, Pfizer, AstraZeneca, Institute of Cancer Research, United Kingdom, UNICANCER, Gustave Roussy, Cancer Campus, Grand Paris, Invitae Corporation
ER+ Breast Cancer, HER2-negative Breast Cancer
09/27
09/30
NCT05463263: A Phase 1/2 Study of STP938 for Adult Subjects With Relapsed/Refractory B-Cell and T-Cell Lymphomas

Recruiting
1/2
180
Europe, US
STP938
Step Pharma, SAS
Lymphoma, B-Cell, Lymphoma, T-Cell
12/25
12/25
NCT05756322: The Safety and Tolerability of LBS-007 in Patients with Relapsed or Resistant Acute Leukaemias

Recruiting
1/2
90
US, RoW
LBS-007
Lin BioScience, Inc, Lin BioScience Pty Ltd
Relapsed or Resistant Acute Leukaemias
12/25
12/25
NCT04534686: CogXergaming to Promote Physical Activity and Cognitive Function in Frail Older Adults

Completed
N/A
50
US
CogXergaming, Cognitive training, Matter of Balance Training, Conventional training
University of Illinois at Chicago
Frail Older Adults
12/22
03/23
NCT06261216: Association Between Lifetime Physical Activity and Exercise and the Development of Wild-type Transthyretin Amyloid Cardiomyopathy

Recruiting
N/A
252
Europe
Interview
Medical University of Graz, Medical University Innsbruck
Amyloid Cardiomyopathy, Wild Type ATTR Amyloidosis
02/25
02/25
NCT06727240: Safe-Infusion Study

Recruiting
N/A
548
Europe
Intervention
Interlinked AB, Parc Sanitari Sant Joan de Déu, Centro Hospitalar e Universitário de Coimbra, E.P.E.
Intravenous Access, Medical Device
12/24
03/25
Elkhashab, Magdy
D-LIVR, NCT03719313 / 2018-003167-54: Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2a

Completed
3
407
Europe, Canada, US, RoW
Lonafarnib, EBP994, Sarasar, LNF, Ritonavir, Norvir, RTV, PEG IFN-alfa-2a, Pegasys, pegylated interferon-alfa, Placebo Lonafarnib, Placebo Ritonavir
Eiger BioPharmaceuticals
Hepatitis Delta Virus
10/22
03/23
B-Well 2, NCT05630820 / 2022-002268-53: Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B

Active, not recruiting
3
871
Europe, Canada, Japan, US, RoW
Bepirovirsen, Placebo
GlaxoSmithKline, GlaxoSmithKline Research & Development Limited
Chronic Hepatitis B, Hepatitis B, Chronic
11/25
05/26
NAVIGATE, NCT04365868 / 2019-001983-31: Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

Active, not recruiting
2b
357
Europe, Canada, US, RoW
belapectin, GR-MD-02, galactoarabino rhamnogalacturonate, Placebo
Galectin Therapeutics Inc., Galectin Therapeutics Inc
Prevention of Esophageal Varices, NASH - Nonalcoholic Steatohepatitis, Cirrhosis
12/24
12/24
Magnes, Marzena
D-LIVR, NCT03719313 / 2018-003167-54: Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2a

Completed
3
407
Europe, Canada, US, RoW
Lonafarnib, EBP994, Sarasar, LNF, Ritonavir, Norvir, RTV, PEG IFN-alfa-2a, Pegasys, pegylated interferon-alfa, Placebo Lonafarnib, Placebo Ritonavir
Eiger BioPharmaceuticals
Hepatitis Delta Virus
10/22
03/23
Mahmood, Muhammad
NCT04658264: Nutrient Profiling and Bio-efficacy of Wheat-Barley Composite Flour in Type-2 Diabetes a in Randomized Control Clinical Trial

Not yet recruiting
1
70
RoW
Wheat-Barley Composite flour
University of Veterinary and Animal Sciences, Lahore - Pakistan
Barley/Wheat Composite Flour in Type-2 Diabetes
07/21
07/21
Fragoso, Eva
NAVIGATE, NCT04365868 / 2019-001983-31: Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

Active, not recruiting
2b
357
Europe, Canada, US, RoW
belapectin, GR-MD-02, galactoarabino rhamnogalacturonate, Placebo
Galectin Therapeutics Inc., Galectin Therapeutics Inc
Prevention of Esophageal Varices, NASH - Nonalcoholic Steatohepatitis, Cirrhosis
12/24
12/24

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