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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
CHABANNE, Russell
HAP-DEX, NCT06269900: Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype	Not yet recruiting	3	450	Europe	Dexamethasone, Placebo	Nantes University Hospital	Hospital Acquired Pneumonia	03/26	08/26
NIPA, NCT05008926: The Study Naloxegol Administration to Prevent Opioids Induced Gastrointestinal Motility Disturbance in Brain Injured PAtients	Recruiting	3	370	Europe	Naloxegol, Placebo	University Hospital, Brest	Brain Injuries	03/26	09/26
TREAT-HAP, NCT05914584: "Baricitinib for Treating Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype.	Not yet recruiting	3	450	Europe	Baricitinib 4 MG	Nantes University Hospital	Hospital-acquired Pneumonia	08/25	12/25
NCT03954041 / 2018-003858-24: A Study to Evaluate the Efficacy and Safety of BIIB093 in Participants With Brain Contusion	Terminated	2	92	Europe, Japan, US, RoW	BIIB093, Glibenclamide, CIRARA, RP 1127, Placebo	Remedy Pharmaceuticals, Inc.	Brain Contusion	06/23	06/23
COMET-AIS, NCT05051397: CO2 Modulation in Endovascular Thrombectomy for Acute Ischemic Stroke	Recruiting	2	50	Europe	HYPERCAPNIA, NORMOCAPNIA	University Hospital, Clermont-Ferrand	Ischemic Stroke, Acute, Thrombectomy, Anesthesia, General, Cerebrovascular Circulation, Carbon Dioxide	06/24	10/24
SPIDERMAN, NCT04023305: Sevoflurane PharmacokInetics in ARDS	Terminated	N/A	37	Europe	Deep sedation by Sevoflurane on the Morphotype of ARDS in ICU patieNts	University Hospital, Clermont-Ferrand	Acute Respiratory Distress Syndrome	12/21	01/22
DrainICU, NCT04438317: Thoracic Drains in Intensive Care Units: Comparison of Seldinger and Surgical Methods	Completed	N/A	227	Europe	Pleural drainage procedure with Seldinger procedure, Pleural drainage procedure with surgical-like technique	University Hospital, Clermont-Ferrand	Pleural Effusion, Pneumothorax, Hemothorax	04/23	06/23
Biper, NCT04080440: Brain-injured Patients Extubation Readiness Study	Recruiting	N/A	660	Europe	Extubation readiness clinical score, Standard of care	University Hospital, Clermont-Ferrand, AZUREA Network (www.azurea.org), ANARLF Network, Direction Générale de l'Offre de Soin (DGOS)	Mechanical Ventilator Weaning, Acute Brain Injury, Altered Level of Consciousness, Mechanical Ventilation, Airway Control	02/27	10/27