| Wong, Robert |
INSITE-DME, NCT05610319: Treat & Extend Versus Fixed Dosing with Faricimab for Management of Diabetic Macular Edema: a Pragmatic, Multi-center, Open-label, Randomized, Controlled Trial |
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| Active, not recruiting | 4 | 446 | Europe, Canada, US, RoW | Faricimab | McMaster University, Hoffmann-La Roche | Diabetic Macular Edema | 12/26 | 12/26 | | |
ARCHER II, NCT06510816: A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA) |
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| Recruiting | 3 | 630 | US | ANX007, Sham Administration | Annexon, Inc. | Geographic Atrophy | 10/26 | 10/27 | | |
| Recruiting | 3 | 560 | US | Fenofibrate, Placebo | Jaeb Center for Health Research, National Institutes of Health (NIH), National Eye Institute (NEI), Juvenile Diabetes Research Foundation, Roche Pharma AG, The Leona M. and Harry B. Helmsley Charitable Trust | Diabetic Retinopathy | 04/29 | 04/29 | | |
GION, NCT06178055: A Study of the Efficacy and Safety of KUS121 in Participants With Acute Non-Arteritic Central Retinal Artery Occlusion (CRAO) |
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| Active, not recruiting | 2 | 75 | US | KUS121 high dose, KUS121 low dose, Sham procedure | Kyoto Drug Discovery and Development Co., Ltd. | Central Retinal Artery Occlusion | 03/25 | 12/25 | | |
SIGLEC, NCT05839041: A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD) |
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| Active, not recruiting | 2 | 300 | US | AVD-104, Avacincaptad | Aviceda Therapeutics, Inc. | Geographic Atrophy of the Macula, Macular Degeneration | 09/25 | 09/26 | | |
NCT06116916: Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema |
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| Recruiting | 2 | 150 | Japan, US, RoW | KHK4951, Aflibercept Injection | Kyowa Kirin Co., Ltd. | Diabetic Macular Edema (DME) | 11/25 | 12/25 | | |
NCT06116890: Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration |
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| Recruiting | 2 | 180 | Japan, US, RoW | KHK4951, Aflibercept Injection | Kyowa Kirin Co., Ltd. | Neovascular Age-Related Macular Degeneration (nAMD) | 11/25 | 12/25 | | |
| Active, not recruiting | 2 | 179 | US | Faricimab | Greater Houston Retina Research, Genentech, Inc. | Non-Proliferative Diabetic Retinopathy | 03/26 | 04/26 | | |
| Recruiting | 1/2 | 215 | US | 4D-150 IVT, Aflibercept IVT | 4D Molecular Therapeutics | Neovascular (Wet) Age-Related Macular Degeneration | 11/25 | 11/26 | | |
ALTUS, NCT05064553: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk |
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| Recruiting | N/A | 2500 | US | Study CT/MRI Imaging, Standard of Care CT/MRI Imaging, Oncoguard™ Liver Test | Exact Sciences Corporation | Hepatocellular Carcinoma, Hepatocellular Cancer, Hepatitis B, Cirrhosis, Liver Cancer | 01/25 | 04/26 | | |
| Shah, Rajesh |
NCT05458791: Intra-arterial Perfusion in Interventional Radiology |
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| Recruiting | N/A | 20 | US | Intra-arterial Perfusion | Palo Alto Veterans Institute for Research, Canon Medical Systems, USA | Hepatocellular Carcinoma | 07/23 | 01/24 | | |
| Yang, Ju Dong |
NCT06514027: Study of BEBT-109 in Subjects With Non-Small Cell Lung Cancer Carrying EGFR Exon 20 Insertion Mutations |
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| Not yet recruiting | 2 | 30 | RoW | BEBT-109 Capsules, KCBT-1083, Pemetrexed Disodium for Injection, Carboplatin Injection, Cisplatin Injection | BeBetter Med Inc | Non Small Cell Lung Cancer | 06/27 | 11/27 | | |
NCT03878550: Case-Control Study of the Glycotest™ HCC Panel vs AFP for the Detection of Early-stage Hepatocellular Carcinoma |
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| Active, not recruiting | N/A | 766 | US, RoW | | Glycotest, Inc. | Carcinoma, Hepatocellular, Cirrhosis, Liver | 08/23 | 12/24 | | |
ALTUS, NCT05064553: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk |
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| Recruiting | N/A | 2500 | US | Study CT/MRI Imaging, Standard of Care CT/MRI Imaging, Oncoguard™ Liver Test | Exact Sciences Corporation | Hepatocellular Carcinoma, Hepatocellular Cancer, Hepatitis B, Cirrhosis, Liver Cancer | 01/25 | 04/26 | | |
| Vasanawala, Minal |
PSMAddition, NCT04720157 / 2020-003968-56: An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With SoC, Versus SoC Alone, in Adult Male Patients With mHSPC |
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| Active, not recruiting | 3 | 1145 | Europe, Canada, Japan, US, RoW | 177Lu-PSMA-617, 68Ga-PSMA-11, ARDT, ADT | Novartis Pharmaceuticals, Alliance Foundation Trials, LLC., RTOG Foundation, Inc. | Prostatic Neoplasms | 07/25 | 02/26 | | |
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NCT04726215: Imaging of T-cell Activation With [18F]F-AraG in Advanced Non Small Cell Lung Cancer |
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| Recruiting | 2 | 50 | US | [18F]F AraG | CellSight Technologies, Inc. | Non Small Cell Lung Cancer | 10/24 | 10/24 | | |
| Kishore, Sirish |
MRI, NCT05700682: Perfusion -targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee |
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| Recruiting | N/A | 120 | US | Shoulder/Hip/Knee Embolization with Embozene Microspheres | Palo Alto Veterans Institute for Research, Varian Medical Systems | Osteoarthritis, Knee, Osteoarthritis, Hip, Osteo Arthritis Shoulders, Synovitis of Knee, Synovitis/Tenosynovitis - Hip, Synovitis, Pain, Chronic | 03/26 | 08/26 | | |
| Okafor, Michael |
NCT04781387: Evaluation of CRS3123 vs. Oral Vancomycin in Adult Patients With Clostridioides Difficile Infection |
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| Active, not recruiting | 2 | 108 | Canada, US | CRS3123, Active Comparator | Crestone, Inc, National Institute of Allergy and Infectious Diseases (NIAID) | Clostridioides Difficile Infection | 02/24 | 04/24 | | |
ALTUS, NCT05064553: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk |
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| Recruiting | N/A | 2500 | US | Study CT/MRI Imaging, Standard of Care CT/MRI Imaging, Oncoguard™ Liver Test | Exact Sciences Corporation | Hepatocellular Carcinoma, Hepatocellular Cancer, Hepatitis B, Cirrhosis, Liver Cancer | 01/25 | 04/26 | | |
| Recruiting | N/A | 1000 | US | MicroVention Mechanical Thrombectomy Devices as first-line treatment | Microvention-Terumo, Inc. | Acute Ischemic Stroke, Vessel Occlusion, Stroke, Ischemic | 12/25 | 12/25 | | |
| Liao, Meimei |
ALTUS, NCT05064553: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk |
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| Recruiting | N/A | 2500 | US | Study CT/MRI Imaging, Standard of Care CT/MRI Imaging, Oncoguard™ Liver Test | Exact Sciences Corporation | Hepatocellular Carcinoma, Hepatocellular Cancer, Hepatitis B, Cirrhosis, Liver Cancer | 01/25 | 04/26 | | |
| Bultman, Eric |
MRI, NCT05700682: Perfusion -targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee |
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| Recruiting | N/A | 120 | US | Shoulder/Hip/Knee Embolization with Embozene Microspheres | Palo Alto Veterans Institute for Research, Varian Medical Systems | Osteoarthritis, Knee, Osteoarthritis, Hip, Osteo Arthritis Shoulders, Synovitis of Knee, Synovitis/Tenosynovitis - Hip, Synovitis, Pain, Chronic | 03/26 | 08/26 | | |
