| KLOUCHE, Kada |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
|
|
| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
| Not yet recruiting | 3 | 610 | Europe | Levosimendan 2.5 MG/ML Injectable Solution, Placebo | Central Hospital, Nancy, France | Cardiogenic Shock | 07/23 | 06/24 | | |
| Recruiting | 3 | 272 | Europe | 56 days of weight-adjusted L-Carnitine treatment, 10 days of intravenous placebo (isotonic saline) | Centre Hospitalier Universitaire de Nīmes | Severe Sepsis, Shock, Septic, Acute Kidney Injury | 05/25 | 05/26 | | |
DE-RISK WF, NCT04696406: Multicenter, Multinational, Clinical Trial of the Performance of RESPINOR DXT to Identify Patients at Increased Risk of Weaning Failure |
|
|
| Completed | N/A | 193 | Europe | RESPINOR DXT | Respinor AS, The Research Council of Norway | Respiratory Failure | 03/22 | 04/22 | | |
| Active, not recruiting | N/A | 1346 | Europe, RoW | Family members of patients admitted to the ICU, Health care professionals, Patients | Nantes University Hospital, Assistance Publique - Hôpitaux de Paris, Assistance Publique Hopitaux De Marseille | Stress Disorders, Post-Traumatic, Family Members | 01/24 | 07/24 | | |
WeCAN, NCT06214390: Urinary Parameters to Predict Weaning of Renal Replacement Therapy in the Critically Ill |
|
|
| Not yet recruiting | N/A | 600 | Europe | Single strategy, Combined strategy | University Hospital, Montpellier | Acute Kidney Injury | 09/25 | 12/25 | | |
HyperBetashock, NCT04748796: Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility |
|
|
| Recruiting | N/A | 360 | Europe | echocardiography, Landiolol | Centre Hospitalier Universitaire, Amiens, CH Dieppe, CH Elbeuf, CH Le Havre, Centre Hospitalier de Beauvais, CH Compiègne, CH Laon, University Hospital, Caen, CH Cherbourg, University Hospital, Lille, CH Douai, CH Montreuil, Centre Hospitalier de Roubaix, Centre Hospitalier de Bethune, CH Lomme, Centre Hospitalier de Lens, Tourcoing Hospital, Centre Hospitalier VALENCIENNES, Centre Hospitalier Arras, Hospital Ambroise Paré Paris, University Hospital, Brest, Henri Mondor University Hospital, Hospital Avicenne, University Hospital, Montpellier, CH Calais, Hôpital Edouard Herriot, Centre Hospitalier Universitaire de Nīmes, Groupe Hospitalier Pitié-Salpêtrière | Septic Shock, Tachycardia, Mortality During Septic Shock, Beta-blocker | 02/24 | 03/24 | | |
| Recruiting | N/A | 220 | Europe | Remote ischemic conditioning, No remote ischemic conditioning | Hospices Civils de Lyon | Out-Of-Hospital Cardiac Arrest | 06/26 | 10/26 | | |
| Recruiting | N/A | 304 | Europe | ECCO2R | Assistance Publique - Hôpitaux de Paris, Ministry of Health, France, Xenios AG | COPD Acute Exacerbation | 06/25 | 04/26 | | |
| ARGAUD, Laurent |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
|
|
| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
| Recruiting | 3 | 270 | Europe | Placebos, Dobutamine | University Hospital, Limoges, Centre d'Investigation Clinique 1415 | Sepsis, Cardiomyopathies, Hypoperfusion, Left Ventricular Systolic Dysfunction | 12/24 | 12/24 | | |
| Recruiting | 3 | 650 | Europe, Canada, RoW | Alteplase, Placebo | Assistance Publique - Hôpitaux de Paris, Johannes Gutenberg University Mainz, Life Sciences Research Partners (D Collen Research Foundation), Canadian Institutes of Health Research (CIHR), Instituto de Salud Carlos III, International Network of VENous Thromboembolism Clinical Research Networks, Boehringer Ingelheim | Pulmonary Embolism | 09/25 | 08/27 | | |
RICO, NCT04392401: COVID-19 - Study of the Kinetics of the Immune Response During the Intensive Care Unit Stay in Adult Patients Infected With SARS-CoV-2: Multicentric Non Interventional Study |
|
|
| Recruiting | N/A | 200 | Europe | Collection of blood samples in order to create a biocollection | Hospices Civils de Lyon, BioMérieux | Intensive Care Unit, SARS-Cov-2 | 05/22 | 05/22 | | |
CovidEP, NCT04751643: Therapeutic Plasma Exchange to Alleviate Hyperinflammatory Condition During Severe Covid-19 Infections |
|
|
| Recruiting | N/A | 132 | Europe | Therapeutic plasma exchange : 3 sessions in 3 consecutive days (day 1 to day 3), Usual treatments in intensive care unit according to the current state of knowledge | Hospices Civils de Lyon | Intensive Care Units, ARDS, Human, Covid19 | 12/22 | 12/22 | | |
VT4COVID, NCT04349618: Ultraprotective Ventilation Without Extracorporeal Circulation During COVID 19 Pneumonia |
|
|
| Recruiting | N/A | 200 | Europe | PROTECTIVE VENTILATION, ULTRAPROTECTIVE VENTILATION | Hospices Civils de Lyon | Acute Respiratory Distress Syndrome, COVID19, Sars-CoV2, Pneumonia | 04/23 | 04/23 | | |
| Active, not recruiting | N/A | 1346 | Europe, RoW | Family members of patients admitted to the ICU, Health care professionals, Patients | Nantes University Hospital, Assistance Publique - Hôpitaux de Paris, Assistance Publique Hopitaux De Marseille | Stress Disorders, Post-Traumatic, Family Members | 01/24 | 07/24 | | |
| Recruiting | N/A | 300 | Europe | Skin biopsy for genetic analyze | Hospices Civils de Lyon | Legionella | 01/24 | 01/25 | | |
EXSUPEEP, NCT05147636: EXtubation With SUctioning or With Positive End-Expiratory Pressure in Intensive Care Unit |
|
|
| Recruiting | N/A | 424 | Europe | Extubation with PEEP, Endotracheal Aspiration | Centre Hospitalier de Bourg en Bresse, Direction Générale de l'Offre de Soins, Hospices Civils de Lyon | Extubation in Intensive Care Unit | 12/24 | 01/25 | | |
IDBIORIV, NCT06219135: Evaluation of the Performance of the Method in Pathogen Identification and Antibiotic Susceptibility Testing in Patients With Sepsis |
|
|
| Recruiting | N/A | 1372 | Europe | no intervention - Contamination group, blood sample - Bacteraemia group | Hospices Civils de Lyon | Sepsis | 01/26 | 05/26 | | |
| Recruiting | N/A | 220 | Europe | Remote ischemic conditioning, No remote ischemic conditioning | Hospices Civils de Lyon | Out-Of-Hospital Cardiac Arrest | 06/26 | 10/26 | | |
| LOUIS, Guillaume |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
|
|
| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
| Not yet recruiting | 3 | 610 | Europe | Levosimendan 2.5 MG/ML Injectable Solution, Placebo | Central Hospital, Nancy, France | Cardiogenic Shock | 07/23 | 06/24 | | |
EMPASHOCK, NCT05879276: Effect at 3 Months of Early Empagliflozin Initiation in Cardiogenic Shock Patients on Mortality, Rehospitalization, Left Ventricular Ejection Fraction and Renal Function. |
|
|
| Not yet recruiting | 3 | 164 | Europe | Empagliflozin 10 MG | Central Hospital, Nancy, France | Cardiogenic Shock | 01/26 | 01/26 | | |
| Completed | N/A | 1058 | Europe | | Centre Hospitalier Régional Metz-Thionville | SARS CoV 2 Infection | 05/23 | 05/23 | | |
NCT04494074: Fever Control Using External Cooling in Mechanically Ventilated Patients With Septic Shock |
|
|
| Recruiting | N/A | 820 | Europe | External Cooling | Centre Hospitalier Intercommunal Creteil | Septic Shock | 12/26 | 12/26 | | |
| TROCHE, Gilles |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
|
|
| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
| BACHOUMAS, Konstantinos |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
|
|
| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
TestICUs, NCT03678233: Efficacy of Testosterone Gel to Restore Normal Serum Values of Testosterone During the Acute Phase of Critical Illness in Adult ICU Patients |
|
|
| Recruiting | 2 | 30 | Europe | AndroGel 16.2 mg/L | University Hospital, Clermont-Ferrand | Hypermetabolism in ICU, Loss of Muscle Mass, Functional Disability After ICU, ICU Acquired Hypogonadism, Treatment With Testosterone Gel in ICU | 06/25 | 06/25 | | |
TestICUs, NCT05825092: Effects of Early Testosterone Gel Administration on Physical Performance in the Critically Ill |
|
|
| Recruiting | 2 | 600 | Europe | Androgel Topical Product, Androgel 1.62% Transdermal Gel, Placebo, Physical performance, Muscle strength, Muscular mass, Test: Functional status, Oxygen muscular consumption | University Hospital, Clermont-Ferrand | Critical Illness | 09/25 | 04/27 | | |
| SACCHERI, Clément |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
|
|
| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
| Recruiting | N/A | 150 | Europe | | Centre Hospitalier Universitaire de Nice | COVID, ARDS, Quality of Life | 06/25 | 12/25 | | |
| DARTEVEL, Anais |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
|
|
| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
| ARRIVE, François |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
|
|
| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
