| TROCHE, Gilles |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
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| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
| Weiss, Emmanuel |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
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| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
HAP-DEX, NCT06269900: Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype |
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| Not yet recruiting | 3 | 450 | Europe | Dexamethasone, Placebo | Nantes University Hospital | Hospital Acquired Pneumonia | 03/26 | 08/26 | | |
NCT06344442: Low-dose Arginine-vasopressin Supplementation on Post-transplant Acute Kidney Injury After Liver Transplantation (AVENIR Trial) |
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| Not yet recruiting | 3 | 304 | Europe | Arginine vasopressin, Norepinephrine | Assistance Publique - Hôpitaux de Paris | Acute Kidney Injury Post Liver Transplantation | 06/26 | 06/26 | | |
| Not yet recruiting | 3 | 196 | Europe | Gentamicin, Placebo, Metronidazole | Assistance Publique - Hôpitaux de Paris | Acute Mesenteric Ischemia | 10/27 | 10/27 | | |
TREAT-HAP, NCT05914584: "Baricitinib for Treating Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype. |
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| Not yet recruiting | 3 | 450 | Europe | Baricitinib 4 MG | Nantes University Hospital | Hospital-acquired Pneumonia | 08/25 | 12/25 | | |
| Completed | N/A | 335 | Europe | | Assistance Publique - Hôpitaux de Paris | Cirrhosis | 07/23 | 02/24 | | |
DIRECTABDO, NCT04925388: Impact of Rapid Molecular Diagnostic Method on Antibiotics Exposure Duration in ICU Patients With Postoperative Peritonitis |
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| Terminated | N/A | 16 | Europe | rapid molecular diagnosis, conventional method analysis | Assistance Publique - Hôpitaux de Paris | Postoperative Peritonitis | 02/24 | 03/24 | | |
PEFLA, NCT06011187: Assisted Fluid Management (AFM) System and Postoperative Outcome After High-risk Abdominal Surgery |
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| Recruiting | N/A | 2000 | Europe, Canada, US | Routine care, AFM | Assistance Publique - Hôpitaux de Paris | Decision Support System, Outcome | 05/26 | 12/26 | | |
| BACHOUMAS, Konstantinos |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
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| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
TestICUs, NCT03678233: Efficacy of Testosterone Gel to Restore Normal Serum Values of Testosterone During the Acute Phase of Critical Illness in Adult ICU Patients |
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| Recruiting | 2 | 30 | Europe | AndroGel 16.2 mg/L | University Hospital, Clermont-Ferrand | Hypermetabolism in ICU, Loss of Muscle Mass, Functional Disability After ICU, ICU Acquired Hypogonadism, Treatment With Testosterone Gel in ICU | 06/25 | 06/25 | | |
TestICUs, NCT05825092: Effects of Early Testosterone Gel Administration on Physical Performance in the Critically Ill |
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| Recruiting | 2 | 600 | Europe | Androgel Topical Product, Androgel 1.62% Transdermal Gel, Placebo, Physical performance, Muscle strength, Muscular mass, Test: Functional status, Oxygen muscular consumption | University Hospital, Clermont-Ferrand | Critical Illness | 09/25 | 04/27 | | |
| Dupuis, Claire |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
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| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
TestICUs, NCT05825092: Effects of Early Testosterone Gel Administration on Physical Performance in the Critically Ill |
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| Recruiting | 2 | 600 | Europe | Androgel Topical Product, Androgel 1.62% Transdermal Gel, Placebo, Physical performance, Muscle strength, Muscular mass, Test: Functional status, Oxygen muscular consumption | University Hospital, Clermont-Ferrand | Critical Illness | 09/25 | 04/27 | | |
VT4COVID, NCT04349618: Ultraprotective Ventilation Without Extracorporeal Circulation During COVID 19 Pneumonia |
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| Recruiting | N/A | 200 | Europe | PROTECTIVE VENTILATION, ULTRAPROTECTIVE VENTILATION | Hospices Civils de Lyon | Acute Respiratory Distress Syndrome, COVID19, Sars-CoV2, Pneumonia | 04/23 | 04/23 | | |
| Recruiting | N/A | 96 | Europe | Trendelenburg maneuver, End-expiratory occlusion test (EE OCC), End-expiratory and end-inspiratory occlusion test (EI OCC), Tidal volume challenge, Fluid bolus (reference diagnostic method) | Hospices Civils de Lyon | Acute Respiratory Distress Syndrome | 10/26 | 10/26 | | |
| SACCHERI, Clément |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
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| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
| Recruiting | N/A | 150 | Europe | | Centre Hospitalier Universitaire de Nice | COVID, ARDS, Quality of Life | 06/25 | 12/25 | | |
| DARREAU, Cédric |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
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| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
| Recruiting | N/A | 200 | Europe | | Centre Hospitalier le Mans | Catheter Complications | 01/25 | 03/25 | | |
| DARTEVEL, Anais |
BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis |
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| Recruiting | 4 | 600 | Europe | continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group | Assistance Publique - Hôpitaux de Paris | Sepsis | 09/24 | 01/25 | | |
