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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Raddatz, Bettina
NCT04781543 / 2020-005764-62: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis Jan 2024 - Dec 2024: Data from trial for diffuse cutaneous systemic sclerosis	Terminated	2	301	Europe, RoW	HZN-825 BID, Placebo, HZN-825 QD	Amgen, Horizon Therapeutics USA, Inc	Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic	02/25	02/25
Medina, Hugo
NCT04781543 / 2020-005764-62: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis Jan 2024 - Dec 2024: Data from trial for diffuse cutaneous systemic sclerosis	Terminated	2	301	Europe, RoW	HZN-825 BID, Placebo, HZN-825 QD	Amgen, Horizon Therapeutics USA, Inc	Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic	02/25	02/25
NCT05626751 / 2021-006271-42: An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc)	Terminated	2	174	Europe, Japan, US, RoW	HZN-825	Amgen, Horizon Therapeutics USA, Inc, Horizon Therapeuthics USA, Inc	Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic	02/25	02/25
Bergmann, Christina
NCT04781543 / 2020-005764-62: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis Jan 2024 - Dec 2024: Data from trial for diffuse cutaneous systemic sclerosis	Terminated	2	301	Europe, RoW	HZN-825 BID, Placebo, HZN-825 QD	Amgen, Horizon Therapeutics USA, Inc	Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic	02/25	02/25

Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Raddatz, Bettina
NCT04781543 / 2020-005764-62: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis Jan 2024 - Dec 2024: Data from trial for diffuse cutaneous systemic sclerosis	Terminated	2	301	Europe, RoW	HZN-825 BID, Placebo, HZN-825 QD	Amgen, Horizon Therapeutics USA, Inc	Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic	02/25	02/25
Medina, Hugo
NCT04781543 / 2020-005764-62: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis Jan 2024 - Dec 2024: Data from trial for diffuse cutaneous systemic sclerosis	Terminated	2	301	Europe, RoW	HZN-825 BID, Placebo, HZN-825 QD	Amgen, Horizon Therapeutics USA, Inc	Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic	02/25	02/25
NCT05626751 / 2021-006271-42: An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc)	Terminated	2	174	Europe, Japan, US, RoW	HZN-825	Amgen, Horizon Therapeutics USA, Inc, Horizon Therapeuthics USA, Inc	Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic	02/25	02/25
Bergmann, Christina
NCT04781543 / 2020-005764-62: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis Jan 2024 - Dec 2024: Data from trial for diffuse cutaneous systemic sclerosis	Terminated	2	301	Europe, RoW	HZN-825 BID, Placebo, HZN-825 QD	Amgen, Horizon Therapeutics USA, Inc	Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic	02/25	02/25