- Respiratory Unit, IRCCS Foundation Policlinico San Matteo Trials

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Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Mondoni, Michele

FULMISCAP, NCT06516601: Fulminant Severe CAP - an Observational Study

Recruiting

N/A

1460

Europe

no intervention

University of Trieste

Community-acquired Pneumonia, Severe Pneumonia, ARDS, Human, Sepsis

09/24

10/24

ULYSSES, NCT05634200: Utility of Bronchoscopy in Patients With Haemoptysis and Negative Chest CT Scan

Recruiting

N/A

150

Europe

Bronchoscopy

University of Milan

Hemoptysis

10/24

10/25

Corsico, Angelo

FGCL-3019-095, NCT04419558 / 2020-000697-22: Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Apr 2024 - Sep 2024: Topline data from ZEPHYRUS-2 trial for IPF

Terminated

372

Europe, US, RoW

Pamrevlumab, FG-3019, Placebo

FibroGen

Idiopathic Pulmonary Fibrosis

09/23

NCT06165341: Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

Recruiting

Europe, Canada, US

Fazirsiran Injection, TAK-999, ARO-AAT, ADS-001, Placebo

Takeda

Alpha1-Antitrypsin Deficiency

08/28

REPAVID-22, NCT05254990 / 2021-006951-32: Reparixin add-on Therapy to Std Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia

Terminated

409

Europe, US, RoW

Reparixin, Repertaxin L-lysine salt, Placebo, Matched placebo

Dompé Farmaceutici S.p.A

Infectious Pneumonia, Severe COVID-19

09/24

NCT05243680 / 2020-004334-38: An Open-Label Extension Study of GSK3511294 (Depemokimab) in Participants Who Were Previously Enrolled in 206713 (NCT04719832) or 213744 (NCT04718103)

Active, not recruiting

641

Europe, Canada, Japan, US, RoW

GSK3511294 (Depemokimab)

GlaxoSmithKline, Iqvia Pty Ltd

Asthma

05/25

NIMBLE, NCT04718389 / 2020-003612-28: A Study of GSK3511294 (Depemokimab) Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic Phenotype

Feb 2024 - Jun 2024 : Acceptance of regulatory submission in China for CRSwNP

Active, not recruiting

1719

Europe, Canada, Japan, US, RoW

GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo, Standard of care (SoC), Pre-filled Syringes (PFS)

GlaxoSmithKline, Iqvia Pty Ltd

Asthma

09/25

NCT05677971: Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Recruiting

160

Europe, Canada, US, RoW

Fazirsiran Injection, TAK-999, ARO-AAT, ADS-001, Placebo, Sodium chloride

Takeda, Takeda Development Center Americas, Inc.

Alpha1-Antitrypsin Deficiency

03/27

03/29

IRENE, NCT03339063: The Italian REgistry of Pulmonary Non-tuberculous mycobactEria

Recruiting

N/A

500

Europe

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Niguarda Hospital, Azienda Ospedaliera San Gerardo di Monza, ASST Fatebenefratelli Sacco, Fondazione IRCCS Policlinico San Matteo di Pavia, Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, University of Turin, Italy, A.O.U. Città della Salute e della Scienza - Molinette Hospital, Azienda Unità Locale Socio Sanitaria n.9 Treviso, Ospedale Maggiore Di Trieste, Azienda Ospedaliero-Universitaria di Modena, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Università degli Studi di Ferrara, IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy, Azienda Ospedaliero, Universitaria Pisana, Azienda Ospedaliero-Universitaria Careggi, Ospedale San Jacopo, Pistoia, Italy, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Azienda Policlinico Umberto I, Istituto Nazionale per le Malattie Infettive Spallanzani, Roma, Policlinico Universitario, Catania, Azienda Ospedaliera Universitaria Policlinico "G. Martino", Azienda Ospedaliera Cosenza, Azienda Ospedaliero Universitaria di Sassari

Nontuberculous Mycobacteria

12/22

PERSONAS, NCT06320119: Setting a PERSONalized Outcome in ASthma: the Study. A Patient Driven Outcome (PDO) Study

Recruiting

N/A

190

Europe

PDO Group

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Bronchial Asthma

01/25

09/25

AIRVO-BX, NCT04102774: Effect of AIRVO Heated Humidification in Bronchiectasis

Active, not recruiting

N/A

130

Europe

Over-night treatment with myAIRVO2

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, ASST Fatebenefratelli Sacco, Fondazione IRCCS Policlinico San Matteo di Pavia, Ospedale Maggiore Di Trieste, Azienda Ospedaliero-Universitaria di Modena, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Fondazione Salvatore Maugeri, Università degli Studi di Ferrara, Azienda Ospedaliero, Universitaria Pisana, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Ospedale San Paolo, Universita degli Studi di Catania, Azienda Ospedaliera di Padova, University of Palermo, Azienda Ospedaliero-Universitaria di Parma, University of Foggia, Monaldi Hospital, Fondazione Don Carlo Gnocchi Onlus, Ospedale San Donato

Bronchiectasis Adult

01/25

PIANOFORTE, NCT04963140: Self-Management Of Asthma By Forced Oscillation Technique

Recruiting

N/A

200

Europe, RoW

Optimized self-management of asthma, Conventional self-management of asthma

Restech Srl

Asthma

04/24

09/24

ULYSSES, NCT05634200: Utility of Bronchoscopy in Patients With Haemoptysis and Negative Chest CT Scan

Recruiting

N/A

150

Europe

Bronchoscopy

University of Milan

Hemoptysis

10/24

10/25

Corcione, Nadia

ULYSSES, NCT05634200: Utility of Bronchoscopy in Patients With Haemoptysis and Negative Chest CT Scan

Recruiting

N/A

150

Europe

Bronchoscopy

University of Milan

Hemoptysis

10/24

10/25

HiSTENT, NCT06069817: Impact of High Flow Therapy on Complications Related to Airway Stenting

Recruiting

N/A

Europe

High flow nasal cannula, nebulized normal saline

Cardarelli Hospital

Airway Obstruction, Respiratory Infection, Mucus; Plug

11/24

12/24

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Mondoni, Michele

FULMISCAP, NCT06516601: Fulminant Severe CAP - an Observational Study

Recruiting

N/A

1460

Europe

no intervention

University of Trieste

Community-acquired Pneumonia, Severe Pneumonia, ARDS, Human, Sepsis

09/24

10/24

ULYSSES, NCT05634200: Utility of Bronchoscopy in Patients With Haemoptysis and Negative Chest CT Scan

Recruiting

N/A

150

Europe

Bronchoscopy

University of Milan

Hemoptysis

10/24

10/25

Corsico, Angelo

FGCL-3019-095, NCT04419558 / 2020-000697-22: Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Apr 2024 - Sep 2024: Topline data from ZEPHYRUS-2 trial for IPF

Terminated

372

Europe, US, RoW

Pamrevlumab, FG-3019, Placebo

FibroGen

Idiopathic Pulmonary Fibrosis

09/23

NCT06165341: Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

Recruiting

Europe, Canada, US

Fazirsiran Injection, TAK-999, ARO-AAT, ADS-001, Placebo

Takeda

Alpha1-Antitrypsin Deficiency

08/28

REPAVID-22, NCT05254990 / 2021-006951-32: Reparixin add-on Therapy to Std Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia

Terminated

409

Europe, US, RoW

Reparixin, Repertaxin L-lysine salt, Placebo, Matched placebo

Dompé Farmaceutici S.p.A

Infectious Pneumonia, Severe COVID-19

09/24

NCT05243680 / 2020-004334-38: An Open-Label Extension Study of GSK3511294 (Depemokimab) in Participants Who Were Previously Enrolled in 206713 (NCT04719832) or 213744 (NCT04718103)

Active, not recruiting

641

Europe, Canada, Japan, US, RoW

GSK3511294 (Depemokimab)

GlaxoSmithKline, Iqvia Pty Ltd

Asthma

05/25

NIMBLE, NCT04718389 / 2020-003612-28: A Study of GSK3511294 (Depemokimab) Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic Phenotype

Feb 2024 - Jun 2024 : Acceptance of regulatory submission in China for CRSwNP

Active, not recruiting

1719

Europe, Canada, Japan, US, RoW

GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo, Standard of care (SoC), Pre-filled Syringes (PFS)

GlaxoSmithKline, Iqvia Pty Ltd

Asthma

09/25

NCT05677971: Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Recruiting

160

Europe, Canada, US, RoW

Fazirsiran Injection, TAK-999, ARO-AAT, ADS-001, Placebo, Sodium chloride

Takeda, Takeda Development Center Americas, Inc.

Alpha1-Antitrypsin Deficiency

03/27

03/29

IRENE, NCT03339063: The Italian REgistry of Pulmonary Non-tuberculous mycobactEria

Recruiting

N/A

500

Europe

Nontuberculous Mycobacteria

12/22

PERSONAS, NCT06320119: Setting a PERSONalized Outcome in ASthma: the Study. A Patient Driven Outcome (PDO) Study

Recruiting

N/A

190

Europe

PDO Group

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Bronchial Asthma

01/25

09/25

AIRVO-BX, NCT04102774: Effect of AIRVO Heated Humidification in Bronchiectasis

Active, not recruiting

N/A

130

Europe

Over-night treatment with myAIRVO2

Bronchiectasis Adult

01/25

PIANOFORTE, NCT04963140: Self-Management Of Asthma By Forced Oscillation Technique

Recruiting

N/A

200

Europe, RoW

Optimized self-management of asthma, Conventional self-management of asthma

Restech Srl

Asthma

04/24

09/24

ULYSSES, NCT05634200: Utility of Bronchoscopy in Patients With Haemoptysis and Negative Chest CT Scan

Recruiting

N/A

150

Europe

Bronchoscopy

University of Milan

Hemoptysis

10/24

10/25

Corcione, Nadia

ULYSSES, NCT05634200: Utility of Bronchoscopy in Patients With Haemoptysis and Negative Chest CT Scan

Recruiting

N/A

150

Europe

Bronchoscopy

University of Milan

Hemoptysis

10/24

10/25

HiSTENT, NCT06069817: Impact of High Flow Therapy on Complications Related to Airway Stenting

Recruiting

N/A

Europe

High flow nasal cannula, nebulized normal saline

Cardarelli Hospital

Airway Obstruction, Respiratory Infection, Mucus; Plug

11/24

12/24



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