| Antonelli, Massimo |
| Completed | 4 | 520 | Europe, RoW | Non-invasive ventilation, Noninvasive ventilation, NIV, Standard care | Università Vita-Salute San Raffaele | Early Acute Respiratory Failure | 08/23 | 07/24 | | |
| Recruiting | 3 | 1252 | Europe | Albumin, Balanced, Ringer Lactate, Ringer Acetate, Crystalsol | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Istituto Di Ricerche Farmacologiche Mario Negri | Septic Shock | 12/21 | 02/22 | | |
IPERPEEP, NCT04012073: Individualized Positive End-expiratory Pressure Guided by End-expiratory Lung Volume in the Acute Respiratory Distress Syndrome |
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| Recruiting | 3 | 132 | Europe | Invasive Mechanical ventilation, Neuromuscular Blocking Agents, Prone positioning, Resume of spontaneous breathing, Rescue treatments, Weaning from PEEP, Weaning from mechanical ventilation, Extubation | Fondazione Policlinico Universitario Agostino Gemelli IRCCS, ClinicalTrialCenter, FerrarioDati, General Electric | Respiratory Distress Syndrome, Adult | 12/24 | 04/25 | | |
HENIVOTpilot, NCT04502576: Helmet Noninvasive Ventilation vs. High-flow Nasal Cannula in Moderate-to-severe Acute Hypoxemic Respiratory Failure |
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| Completed | N/A | 110 | Europe | Noninvasive respiratory support | Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università degli studi di Chieti, Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva | Respiratory Failure With Hypoxia | 01/21 | 12/22 | | |
NCT04033224: Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure |
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| Recruiting | N/A | 1000 | Europe | Commercial membrane for Extracorporeal Blood Purification Therapy (EBPT) | Careggi Hospital, University of Florence | Critical Illness, Acute Kidney Injury, Sepsis, Systemic Inflammatory Response Syndrome | 12/24 | 12/24 | | |
NCT05403320: Cuff Pressure Control and Evacuation of Subglottic Secretions To Prevent Pneumonia |
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| Completed | N/A | 270 | Europe, RoW | Continuous cuff pressure regulation, Intermittent cuff pressure regulation, Automatic subglottic secretion drainage, Manual subglottic secretion drainage, Tracheobronchial colonization assessment, Microaspiration assessment, VAP assessment | Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of the Sacred Heart | Respiratory Failure | 01/24 | 04/24 | | |
NCT03807414: Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill Patients |
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| Active, not recruiting | N/A | 270 | Europe | oXiris | Careggi Hospital, University of Florence | Critical Illness, Acute Kidney Injury, Sepsis, Systemic Inflammatory Response Syndrome | 12/24 | 12/24 | | |
| Recruiting | N/A | 20 | Europe | Noninvasive support | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Acute Hypoxic Respiratory Failure | 12/24 | 12/24 | | |
NCT06210386: Physiology of Helmet vs. Facemask Noninvasive Ventilation |
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| Recruiting | N/A | 20 | Europe | Noninvasive ventilation | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Acute Hypoxemic Respiratory Failure | 12/24 | 01/25 | | |
| Recruiting | N/A | 1200 | Europe | Noninvasive respiratory support | Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva, Catholic University of the Sacred Heart | Respiratory Failure, Hypoxemic Respiratory Failure | 12/25 | 06/26 | | |
HISTAP, NCT05637606: HIgh Versus STAndard Blood Pressure Target in Hypertensive High-risk Patients Undergoing Major Abdominal Surgery |
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| Recruiting | N/A | 636 | Europe | Ephedrine, Ephedrine bolus, Norepinephrine, norepinephrine infusion, Etilefrine Hydrochloride bolus, Use of pulse pressure and stroke volume variation (PPV and SVV); use of Mini Fluid Challenge (mini_FC), Hemodynamic optimization | Humanitas Clinical and Research Center, Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva | Blood Pressure, Complication,Postoperative, Intraoperative Hypotension | 02/25 | 03/25 | | |
PACCOF, NCT06651047: PK/PD Analysis of Ceftazidime/Avibactam or Cefiderocol With or Without Fosfomycin for the Treatment of Difficult To-treat Gram-negative Infections |
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| Recruiting | N/A | 120 | Europe | | University of Bologna | Gram Negative Infection, Antimicrobial Resistance (AMR) | 09/25 | 09/25 | | |
| Not yet recruiting | N/A | 20 | Europe | Noninvasive ventilation, Positive-pressure ventilation | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Respiratory Insufficiency | 10/25 | 10/25 | | |
| Recruiting | N/A | 126 | Europe | Lower tract respiratory samples, Multiplex PCR assay (Film-array Pneumonia Panel Plus), Lower respiratory tract standard culture, Blood sample standard culture | Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of the Sacred Heart | HAP - Hospital Acquired Pneumonia, VAP - Ventilator Associated Pneumonia | 04/25 | 04/25 | | |
| Meduri, Umberto |
| No trials found |
