Oxford University Hospitals
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 18 Trials 
50 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Boffito, Marta
TPLWH, NCT04944654: Efficacy, Tolerability and Acceptability of Biktarvy by

Terminated
4
1
Europe
BIKTARVY 50Mg-200Mg-25Mg Tablet
Chelsea and Westminster NHS Foundation Trust, Gilead Sciences, Imperial College London
Human Immunodeficiency Virus
05/23
05/23
BIC-T&T, NCT04653194 / 2019-003208-11: Efficacy of BIC/F/TAF Versus Standard of Care in the Treatment of New HIV Infection Diagnoses in the Context of 'Test and Treat'

Completed
3
36
Europe
Biktarvy, Symtuza
Chelsea and Westminster NHS Foundation Trust, Imperial College London, Gilead Sciences
Human Immunodeficiency Virus
07/23
07/23
DORDOL, NCT04892654: Efficacy of Doravirine + Dolutegravir Dual Therapy in the Context of Antiretroviral Therapy Switch

Recruiting
3
150
Europe
Doravirine, Pifeltro, Dolutegravir, Tivicay, Triple cART regimen
Chelsea and Westminster NHS Foundation Trust
HIV-1-infection
11/26
11/27
NCT04120415 / 2019-002818-40: A HIV Vaccine Trial in Individuals Who Started Antiretrovirals During Primary or Chronic Infection (EHVA T02)

Completed
2
2
Europe
Vaccine and vedolizumab (Entyvio), Placebo vaccine and vedolizumab infusion (Entyvio), Placebo vaccine and placebo infusion
ANRS, Emerging Infectious Diseases, EuroVacc Foundation, European AIDS Treatment Group (EATG), Medical Research Council, University College London Hospitals, University of Liverpool, Erasmus Medical Center, Henri Mondor University Hospital, European Georges Pompidou Hospital, Saint-Louis Hospital, Paris, France, Centre Hospitalier Universitaire Vaudois, Chelsea and Westminster Hospital, UK, Universitätsklinikum Hamburg-Eppendorf, Hospital Clinic of Barcelona, Istituto Nazionale Malattie Infettive Lazaro Spallanzani, Imperial College London, Institut d'Investigacions Biomèdiques August Pi i Sunyer, European Commission, Swiss Government
HIV-1-infection
07/23
07/23
RIO, NCT04319367: A Randomised Placebo Controlled Trial of ART Plus Dual Long-acting HIV-specific Broadly Neutralising Antibodies (bNAbs).

Recruiting
2
72
Europe
Investigational Medicinal Product, 10-1074-LS and 3BNC117-LS
Imperial College London, Bill and Melinda Gates Foundation, University of Oxford, Rockefeller University
HIV/AIDS and Infections
07/27
07/27
NCT04950530: The Effect of Biktarvy (B/F/TAF) on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers

Completed
1
25
Europe
BIKTARVY 50Mg-200Mg-25Mg Tablet, BIC/FTC/TAF, Bictegravir
Chelsea and Westminster NHS Foundation Trust
HIV-1-infection
02/24
02/24
TIME, NCT03922269: Trans People Living With HIV Throughout Europe

Recruiting
N/A
200
Europe
Chelsea and Westminster NHS Foundation Trust, ViiV Healthcare
HIV Infections, Gender Identity, Human Immunodeficiency Virus
04/24
10/25
Scarborough, Matthew
SNAP, NCT05137119: Staphylococcus Aureus Network Adaptive Platform Trial

Recruiting
4
8000
Europe, Canada, RoW
Cefazolin, Penicillin, Benzylpenicillin, Penicillin G, Clindamycin, Lincomycin, Vancomycin, Daptomycin, Effectiveness of early switch to oral antibiotics, Whole body FDG PET/CT Imaging
University of Melbourne, Berry Consultants, McGill University Health Centre/Research Institute of the McGill University Health Centre, Menzies School of Health Research, Aotearoa Clinical Trials, Queensland University of Technology, Sunnybrook Health Sciences Centre, Tan Tock Seng Hospital, Telethon Kids Institute, The Peter Doherty Institute for Infection and Immunity, The University of Queensland, UMC Utrecht, Radboud University Medical Center, King's College London, Rambam Health Care Campus, University College, London, Houston Medical Research Institute
Staphylococcus Aureus Bacteremia
12/28
12/28
NCT04238676: Persica 002 Phase 1b PP353 vs Placebo in the Treatment of Low Back Pain

Active, not recruiting
1/2
43
Europe, RoW
PP353, Placebo
Persica Pharmaceuticals Ltd, Micron Research Ltd
Chronic Low-back Pain
12/24
12/24
SOLARIO, NCT03806166: Short or Long Antibiotic Regimes in Orthopaedics

Active, not recruiting
N/A
500
Europe
Shorter Systemic Antibiotics, Standard treatment
Oxford University Hospitals NHS Trust
Osteomyelitis, Prosthetic Joint Infection, Diabetic Foot
12/24
01/25
Nicum, Shibani
ICON9, NCT03278717: Study Evaluating the Efficacy of Maintenance Olaparib and Cediranib or Olaparib Alone in Ovarian Cancer Patients

Recruiting
3
330
Europe, Canada, RoW
Olaparib, Cediranib
University College, London
Ovarian Cancer
12/23
12/23
RAMP 301, NCT06072781: A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Recruiting
3
270
Europe, Canada, US, RoW
avutometinib, avutometinib (VS-6766), Defactinib, defactinib (VS-6063), Pegylated liposomal doxorubicin, Caelyx, Doxil, Lipodox, Paclitaxel, Nov-Onxol, Onxol, Navaplus, Taxol, Letrozole, Femara, Anastrozole, Arimidex
Verastem, Inc., GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Australia New Zealand Gynaecological Oncology Group
Low Grade Serous Ovarian Cancer
10/28
02/31
Horrocks, Iain
GUARDIAN, NCT06713135: A Study on Safety and Effectiveness of Long-term Treatment With Vamorolone in Boys With Duchenne Muscular Dystrophy

Recruiting
4
80
Europe, RoW
vamorolone 40 mg/mL oral suspension, vamorolone
Santhera Pharmaceuticals
Duchenne Muscular Dystrophy
09/28
09/28
MOMENTUM, NCT04004065 / 2019-000601-77: Two-Part Study for Dose Determination of Vesleteplirsen (SRP-5051) (Part A), Then Dose Efficacy (Part B) in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51-Skipping Treatment

Checkmark From MOMENTUM trial for DMD
May 2021 - May 2021: From MOMENTUM trial for DMD
Checkmark Interim data from the MOMENTUM study
Dec 2020 - Dec 2020: Interim data from the MOMENTUM study
Checkmark Data from MOMENTUM trial for Duchenne muscular dystrophy
More
Active, not recruiting
2
62
Europe, Canada, US
Vesleteplirsen, SRP-5051
Sarepta Therapeutics, Inc.
Duchenne Muscular Dystrophy
10/23
01/29
NCT05938023: A Study of ATL1102 or Placebo in Participants With Non-ambulatory Duchenne Muscular Dystrophy

Active, not recruiting
2
48
Europe, RoW
ATL1102 25mg, ATL1102 50mg, Placebo
Percheron Therapeutics
Duchenne Muscular Dystrophy
11/24
03/25
NS, NCT06711692: The U.K. NorthStar Clinical Network

Not yet recruiting
N/A
300
Europe
University College, London, Muscular Dystrophy UK
Duchenne Muscular Dystrophy
04/25
06/25
Rahman, Najib
NCT05711290: Oxygen Nanobubble Drink Impact on Exercise in Pulmonary Fibrosis

Completed
N/A
28
Europe
Oxygen Nanobubble, Placebo
University of Oxford, Oxford University Hospitals NHS Trust
Pulmonary Fibrosis
08/23
08/23
NEWTON, NCT03831386: Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System

Recruiting
N/A
200
Europe, US
Vacuum-Based IPC, Gravity-Based IPC
Johns Hopkins University, Rocket Medical plc, Swedish Medical Center, Medical University of South Carolina, University of Oxford, Vanderbilt University Medical Center, Northwest Community Healthcare
Pleural Effusion
12/26
12/26
PROSPECT, NCT05910112: Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural Intervention

Recruiting
N/A
2000
Europe
Pleural interventions
University of Oxford, Beckton Dickinson
Pleural Diseases, Pleural Mesothelioma, Pneumothorax, Pleural Effusion, Pleural Infection, Pleural Neoplasms, Pleural Metastases, Pleural Effusion, Malignant, Procedural Complication, Complications, Pulmonary
08/24
08/24
LungI-ACT, NCT05888584: Improving Access and Recruitment to Clinical Trials for Lung Cancer Patients

Recruiting
N/A
100
Europe
Research readiness tool
Oxford Brookes University, De Montfort University
Lung Cancer
03/25
03/25
Roy, Pankaj G
ATNEC, NCT04109079: Axillary Management in Breast Cancer Patients with Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy

Recruiting
N/A
1900
Europe
Axillary lymph node dissection, Axillary radiotherapy, Breast or chest wall radiotherapy
University Hospitals of Derby and Burton NHS Foundation Trust
Breast Cancer, Sentinel Lymph Node, Neoplasm, Breast
02/30
02/30
Reynolds, Jeremy
PTRON, NCT02790983: Primary Tumor Research and Outcomes Network

Recruiting
N/A
1350
Europe, Canada, Japan, US, RoW
AO Innovation Translation Center, AO Foundation, AO Spine
Spinal Column Tumor
12/25
12/26
Smith, Gill
NCT02611089: Muscle Connective Tissue in Limb Development and Disease

Recruiting
N/A
45
Europe
Tissue biopsy
King's College London, Great Ormond Street Hospital for Children NHS Foundation Trust, Royal Free Hospital NHS Foundation Trust, Chelsea and Westminster NHS Foundation Trust
Radial Dysplasia
02/26
08/36
Murphy, George
NCT02611089: Muscle Connective Tissue in Limb Development and Disease

Recruiting
N/A
45
Europe
Tissue biopsy
King's College London, Great Ormond Street Hospital for Children NHS Foundation Trust, Royal Free Hospital NHS Foundation Trust, Chelsea and Westminster NHS Foundation Trust
Radial Dysplasia
02/26
08/36
Silva, M
NCT05626764: QUALITOP - Monitoring Multidimensional Aspects of QUAlity of Life After Cancer ImmunoTherapy, an Open Smart Digital Platform for Personalized Prevention and Patient Management

Recruiting
N/A
3000
Europe
QoL & irAEs determinants
Hospices Civils de Lyon
Solid Tumor, Hematologic Cancer
12/23
12/24
Watkinson, Peter
DREaMED, NCT06560931: Defining, Recognising and Escalating Maternal Early Deterioration

Active, not recruiting
N/A
459160
Europe
University of Oxford, NHS England, Guy's and St Thomas' NHS Foundation Trust, King's College London
Pregnancy Complications, Pregnancy, High Risk
05/29
05/29
NCT04545437: The Short and Long-term Cardiovascular Consequences of Critical Illness: The C3 Study

Recruiting
N/A
80000
Europe
Admission to ICU
University of Oxford
Critical Illness, Myocardial Infarction, Stroke, Atrium; Fibrillation, Atrial Flutter
08/23
12/23
vHDU phase 5, NCT05118477: vHDU Phase 5: Impact of an Ambulatory Monitoring System on Deterioration Detection and Clinical Outcomes

Recruiting
N/A
120
Europe
Ambulatory monitoring system, Active alerting system
University of Oxford, National Institute for Health Research, United Kingdom
Surgery, Deterioration, Clinical
03/25
03/25
RE-BLEED, NCT05608577: A Digital Platform for Identifying Bleeding Patients - a Feasibility Study

Active, not recruiting
N/A
200
Europe
University of Oxford, University of Leicester, Oxford University Hospitals NHS Trust
Hemorrhage, Trauma, Gastro Intestinal Bleeding
02/25
02/25
PARADISE, NCT05255224: Predicting AF After Cardiac Surgery

Active, not recruiting
N/A
13684
Europe
Not applicable as observational study
University of Oxford, St. Bartholomew's Hospital, University College, London, Liverpool Heart and Chest Hospital NHS Foundation Trust, Brigham and Women's Hospital, Oxford University Hospitals NHS Trust
Atrial Fibrillation New Onset
05/25
05/25
OPTIC-19, NCT04838106: Outcomes of Patients Who Survived Treatment on an Intensive Care Unit for COVID-19 in England and Wales

Active, not recruiting
N/A
319600
Europe
Not applicable as observational study
University of Oxford, Intensive Care National Audit & Research Centre
Covid19, Myocardial Infarction, Stroke, Critical Illness, Heart Failure, Deep Vein Thrombosis, Pulmonary Embolism, Renal Failure
02/25
02/25
TrAFFIC, NCT05229211: Tracking Atrial Fibrillation After Intensive Care Admission

Recruiting
N/A
100
Europe
Cardiac monitoring, VitalConnect patch
University of Oxford
Atrial Fibrillation New Onset, New Onset Atrial Fibrillation, Atrial Fibrillation
12/25
12/25
Cicconi, Paola
RIO, NCT04319367: A Randomised Placebo Controlled Trial of ART Plus Dual Long-acting HIV-specific Broadly Neutralising Antibodies (bNAbs).

Recruiting
2
72
Europe
Investigational Medicinal Product, 10-1074-LS and 3BNC117-LS
Imperial College London, Bill and Melinda Gates Foundation, University of Oxford, Rockefeller University
HIV/AIDS and Infections
07/27
07/27
NCT06549257: Assessing the Safety, Immunogenicity and Ex-vivo Efficacy of Two Candidate Malaria Transmission Blocking Vaccines, Pfs25-IMX313 and Pfs45/48 Administered Alone and in Combination, in Matrix-M Adjuvant

Not yet recruiting
1/2
56
NA
Pfs25-IMX313, Pfs48/45
University of Oxford, European and Developing Countries Clinical Trials Partnership (EDCTP)
Plasmodium Falciparum Malaria
12/25
12/25
HIV-CORE 006, NCT04553016: A Study to Test Three Experimental HIV Vaccines in Healthy Adults.

Active, not recruiting
1
88
RoW
Vaccine, Placebo
University of Oxford, European and Developing Countries Clinical Trials Partnership (EDCTP), University of Nairobi, KEMRI-Wellcome Trust Collaborative Research Program, MRC/UVRI & LSHTM Uganda Research Unit, International AIDS Vaccine Initiative, Imperial College London, Center for Family Health Research in Zambia
HIV-1-infection
11/22
11/22
NCT05079750: A Study of a New Vaccine Against Two Types of Ebola

Completed
1
26
Europe
ChAdOx1 biEBOV
University of Oxford
Ebola
03/23
03/23
cassell, oliver
MelMarT-II, NCT03860883: Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Recruiting
N/A
2998
Europe, Canada, US, RoW
Wide Local Excision = 1cm Margin, Wide Local Excision = 2cm Margin
Melanoma and Skin Cancer Trials Limited, Norfolk and Norwich University Hospitals NHS Foundation Trust, Canadian Cancer Trials Group, Cancer Trials Ireland, Zuyderland Medical Centre
Cutaneous Melanoma, Stage II
12/29
12/34
Thompson, Sanja
CHIEF PD, NCT04226248: CHIEF-PD (CHolinesterase Inhibitor to prEvent Falls in Parkinson's Disease)

Active, not recruiting
3
600
Europe
Rivastigmine Transdermal System, Placebo Transdermal System
University of Bristol, Royal United Hospitals Bath NHS Foundation Trust
Parkinson Disease
05/24
02/25
Whitestone, Lauren
CHIEF PD, NCT04226248: CHIEF-PD (CHolinesterase Inhibitor to prEvent Falls in Parkinson's Disease)

Active, not recruiting
3
600
Europe
Rivastigmine Transdermal System, Placebo Transdermal System
University of Bristol, Royal United Hospitals Bath NHS Foundation Trust
Parkinson Disease
05/24
02/25
McKechnie, Stuart
PHIND, NCT04009330: Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome

Active, not recruiting
N/A
480
Europe
POC Assay
Queen's University, Belfast, Northern Ireland Clinical Trials Unit, Innovate UK
Acute Respiratory Distress Syndrome (ARDS)
11/23
02/26
Cogswell, Lucy
NCT02611089: Muscle Connective Tissue in Limb Development and Disease

Recruiting
N/A
45
Europe
Tissue biopsy
King's College London, Great Ormond Street Hospital for Children NHS Foundation Trust, Royal Free Hospital NHS Foundation Trust, Chelsea and Westminster NHS Foundation Trust
Radial Dysplasia
02/26
08/36
Ather, Sarim
AI-REACT, NCT06018545: AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation

Active, not recruiting
N/A
33
Europe
Ground truthing, Reading
Oxford University Hospitals NHS Trust
Intracranial Hemorrhages, Acute Ischemic Stroke, Hydrocephalus, Cerebral Infarction, Cerebral Edema, Cerebral Injury
09/23
06/25
AID-CXR, NCT06075836: AI Assisted Detection of Chest X-Rays

Active, not recruiting
N/A
33
Europe
Cases reading, Ground truthing
Oxford University Hospitals NHS Trust
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple, Pulmonary Consolidation, Pneumothorax, Pneumothorax; Acute, Atelectasis, Pulmonary Calcification, Cardiomegaly, Fibrosis Lung, Pleural Effusion, Pleural Effusions, Chronic, Pneumoperitoneum
10/24
06/25
FRACT-AI, NCT06130397: AI Assisted Detection of Fractures on X-Rays

Recruiting
N/A
21
Europe
Cases reading, Ground truthing
Oxford University Hospitals NHS Trust, Gleamer
Fracture, Bone Fracture, Dislocation, Fracture Multiple, Fractures, Closed, Fractures, Open
10/24
06/25
ACCEPT, NCT06027411: Assess the Clinical Effectiveness in AI Prioritising CT Heads

Recruiting
N/A
16800
Europe
qER (qER EU 2.0)
Guy's and St Thomas' NHS Foundation Trust, Qure.ai, NHS Greater Glasgow and Clyde, Northumbria Healthcare NHS Foundation Trust, Oxford University Hospitals NHS Trust
Trauma, Brain, Mass Lesion, Skull Fractures, Hemorrhage, Intracranial, Midline Deviation, Stroke, Ischemic, Encephalomalacia
08/24
08/24
Narbone, Mariapaola
ACCEPT, NCT06027411: Assess the Clinical Effectiveness in AI Prioritising CT Heads

Recruiting
N/A
16800
Europe
qER (qER EU 2.0)
Guy's and St Thomas' NHS Foundation Trust, Qure.ai, NHS Greater Glasgow and Clyde, Northumbria Healthcare NHS Foundation Trust, Oxford University Hospitals NHS Trust
Trauma, Brain, Mass Lesion, Skull Fractures, Hemorrhage, Intracranial, Midline Deviation, Stroke, Ischemic, Encephalomalacia
08/24
08/24
Lee, Regent
VASCULAIDRETRO, NCT06206369: Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression

Recruiting
N/A
11000
Europe, RoW
No intervention, retrospective study
Amsterdam UMC, location VUmc, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Technical University of Twente, Universidade do Porto, Centre Hospitalier Universitaire de Nice, Stichting Allai, Faculty of Medicine, University of Belgrade, Brightfish Be, Hospital District of Helsinki and Uusimaa, University of Bergen, Asklepios Kliniken Hamburg GmbH, University of Oxford, VINČA INSTITUTE OF NUCLEAR SCIENCES Belgrado
Aneurysm Abdominal, Peripheral Arterial Disease
05/29
05/29
Sarker, Sarah
LungI-ACT, NCT05888584: Improving Access and Recruitment to Clinical Trials for Lung Cancer Patients

Recruiting
N/A
100
Europe
Research readiness tool
Oxford Brookes University, De Montfort University
Lung Cancer
03/25
03/25
Balakrishnan, Indran
SNAP, NCT05137119: Staphylococcus Aureus Network Adaptive Platform Trial

Recruiting
4
8000
Europe, Canada, RoW
Cefazolin, Penicillin, Benzylpenicillin, Penicillin G, Clindamycin, Lincomycin, Vancomycin, Daptomycin, Effectiveness of early switch to oral antibiotics, Whole body FDG PET/CT Imaging
University of Melbourne, Berry Consultants, McGill University Health Centre/Research Institute of the McGill University Health Centre, Menzies School of Health Research, Aotearoa Clinical Trials, Queensland University of Technology, Sunnybrook Health Sciences Centre, Tan Tock Seng Hospital, Telethon Kids Institute, The Peter Doherty Institute for Infection and Immunity, The University of Queensland, UMC Utrecht, Radboud University Medical Center, King's College London, Rambam Health Care Campus, University College, London, Houston Medical Research Institute
Staphylococcus Aureus Bacteremia
12/28
12/28
Mokhtar, Ibrahim
PROTECT-UP, NCT06052475: Physiological Versus Right Ventricular Outcome Trial Evaluated for Bradycardia Treatment Upgrades

Recruiting
N/A
155
Europe
Physiological Pacing Upgrade (Conduction System Pacing or Biventricular Pacing), Continued RV Pacing (Right Ventricular Pacing)
Imperial College London
Pacing-Induced Cardiomyopathy, Heart Failure
05/26
08/26

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