University of Colorado, Anschutz Medical Campus
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 44 Trials 
71 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Pollyea, Daniel Aaron
NCT03573024: Venetoclax and Azacitidine for Non-Elderly Adult Patients with Acute Myeloid Leukemia

Active, not recruiting
2
36
US
Azacitidine, Venetoclax
University of Colorado, Denver, AbbVie
Acute Myeloid Leukemia
06/26
06/27
OV-AML-1231, NCT06384261: A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy

Recruiting
2
120
Europe, Canada, US
Cusatuzumab, OV-1001, Venetoclax, Azacitidine
OncoVerity, Inc.
Leukemia, Myeloid, Acute
01/27
06/27
NCT03564873: Omacetaxine + Azacitidine in Untreated Patients With High Grade MDS

Active, not recruiting
1/2
28
US
Omacetaxine, Phase 1, Azacitidine, Phase 2
University of Colorado, Denver
High Grade Myelodysplastic Syndromes
08/24
06/27
IO-202-CL-001, NCT04372433: IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML

Active, not recruiting
1
106
US
IO-202, IO-202 and Azacitidine, IO-202 and AZA, IO-202 and Azacitidine + Venetoclax, IO-202 and AZA + Ven
Immune-Onc Therapeutics, California Institute for Regenerative Medicine (CIRM)
AML With Monocytic Differentiation, CMML
01/26
01/27
NCT06429449: Mitoxantrone for Venetoclax Resistant Acute Myeloid Leukemia

Recruiting
1
30
US
Venetoclax, Venclexta, Venclyxto, Azacitidine, Onureg, Vidaza, Mitoxantrone, Novantrone
University of Colorado, Denver, The Leukemia and Lymphoma Society
Leukemia, Myeloid Leukemia, Monocytic Leukemia
12/26
11/27
NCT04914845: KPT-9274 in Patients with Relapsed and Refractory Acute Myeloid Leukemia

Recruiting
1
40
US
KPT-9274
University of Colorado, Denver, Karyopharm Therapeutics Inc
Acute Myeloid Leukemia, Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
02/26
02/27
20-1319.cc, NCT05287568: CC-486 and Venetoclax for Acute Myeloid Leukemia

Recruiting
1
35
US
Venetoclax, ABT-199, Abbvie, CC-486
University of Colorado, Denver, Bristol-Myers Squibb
AML
03/27
03/29
Smith, Andrew
NIMBLE, NCT04718389 / 2020-003612-28: A Study of GSK3511294 (Depemokimab) Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic Phenotype

Hourglass Feb 2024 - Jun 2024 : Acceptance of regulatory submission in China for CRSwNP
Active, not recruiting
3
1667
Europe, Canada, Japan, US, RoW
GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo, Standard of care (SoC), Pre-filled Syringes (PFS)
GlaxoSmithKline, Iqvia Pty Ltd
Asthma
10/25
10/25
NCT05677451: 24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

Recruiting
3
100
Europe, Canada, Japan, US, RoW
LOU064 (blinded), remibrutinib, placebo
Novartis Pharmaceuticals
Chronic Spontaneous Urticaria
11/25
02/32
NCT05976243: A Study to Investigate Efficacy, Safety, and Tolerability of Remibrutinib Compared With Placebo in Adults With CINDU Inadequately Controlled by H1-antihistamines

Recruiting
3
348
Europe, Canada, Japan, US, RoW
Remibrutinib, Placebo
Novartis Pharmaceuticals
Chronic Inducible Urticaria
03/26
12/28
NCT05513001 / 2022-001034-11: An Extension Study of Long-term Efficacy, Safety and Tolerability of Remibrutinib in Chronic Spontaneous Urticaria Patients Who Completed Preceding Studies With Remibrutinib

Active, not recruiting
3
698
Europe, Canada, Japan, US, RoW
LOU064 (blinded), remibrutinib, Placebo, LOU064 (open label)
Novartis Pharmaceuticals
Chronic Spontaneous Urticaria
08/24
02/27
RAPID-I, NCT03684278: Randomised Treatment of Acute Pancreatitis With Infliximab: Double-blind, Placebo-controlled, Multi-centre Trial

Recruiting
2
290
Europe
Infusion of 5 mg/kg Infliximab, Remicade, Infusion of 10 mg/kg Infliximab, 0.9% Sodium Chloride (Placebo)
University of Liverpool, Bangor University, Liverpool University Hospitals NHS Foundation Trust, Medical Research Council, National Institute for Health Research, United Kingdom, Merck Sharp & Dohme LLC
Acute Pancreatitis
07/26
03/27
CALM-CSU, NCT06077773: Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria

Recruiting
2
154
Europe, Canada, US
Oral EP262, Placebo
Escient Pharmaceuticals, Inc
Chronic Spontaneous Urticaria
06/25
07/25
NCT05432388 / 2021-006950-30: Study of Efficacy, Safety and Tolerability of Remibrutinib in Adult Participants With an Allergy to Peanuts

Recruiting
2
72
Europe, US
remibrutinib, (LOU064), placebo
Novartis Pharmaceuticals, Novartis Pharma AG
Allergy, Peanut
03/25
03/25
NCT03910413: Dual Energy CT as a Noninvasive Method to Screen for Gastroesophageal Varices

Terminated
N/A
11
US
Duel Energy CT
University of Alabama at Birmingham
Gastroesophageal Varices
09/19
07/23
NCT01817192: Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer

Recruiting
N/A
1050
Europe, US
Adjuvant Chemotherapy, Radiographic surveillance, 14-Gene Prognostic Assay
Razor Genomics, Encore Clinical
Non-Small Cell Lung Cancer
05/27
05/27
NCT05966896: Epidural Stimulation to Restore Voluntary Movement Following Spinal Cord Injury

Not yet recruiting
N/A
2
NA
implanted epidural stimulator
University of Colorado, Denver, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Spinal Cord Injuries
01/26
08/26
TITRE, NCT05405426: Trial of Indication-Based Transfusion of Red Blood Cells in ECMO

Recruiting
N/A
228
Canada, US, RoW
Red blood cell transfusion
Boston Children's Hospital
Extracorporeal Membrane Oxygenation, Red Blood Cell Transfusion, Organ Failure, Multiple
10/24
12/25
NCT04161417: Precision-Panc Master Protocol: Personalising Treatment for Pancreatic Cancer

Recruiting
N/A
2500
Europe
Patients with suspected or confirmed pancreatic cancer will be be asked to provide biopsy material for molecular profiling
Judith Dixon-Hughes, Cancer Research UK, NHS Greater Glasgow and Clyde
Neoplasms Pancreatic
12/25
12/25
TARGET-DERM, NCT03661866: A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Recruiting
N/A
15000
Europe, Canada, US
Target PharmaSolutions, Inc.
Atopic Dermatitis, Alopecia Areata, Hidradenitis Suppurativa, Vitiligo, Psoriasis, Chronic Spontaneous Urticaria
12/50
12/50
Amara, Amy
NCT06219629: Parkinson's Disease Progression Study

Recruiting
N/A
70
US
Koneksa Health, Merck Sharp & Dohme LLC, Regeneron Pharmaceuticals
Parkinson Disease
08/25
09/25
NCT05437640: Optimizing Protein Patterns for Skeletal Muscle Preservation and Sleep in the Medical Management of Parkinson Disease

Completed
N/A
12
US
Protein Redistribution Diet, PRD, Protein Consistent Diet, PCD
University of Alabama at Birmingham
Parkinson Disease
11/24
11/24
NCT04796506: Slow Wave Sleep As a Biomarker of Rehabilitation-induced Cognitive Improvement in PD

Recruiting
N/A
120
US
Progressive Resistance Training (PRT), PRT, Delayed Exercise Training (DE), Endurance Training (ET), ET
University of Colorado, Denver, National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Parkinson Disease
03/26
03/26
Bull, Todd M
IMPAHCT, NCT05036135 / 2021-001910-13: A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH)

Terminated
2/3
202
Europe, Canada, US, RoW
AV-101, Placebo
Aerovate Therapeutics, Aerovate Therapeutics, Inc.
Pulmonary Arterial Hypertension
08/24
08/24
NCT03409588: Treatment of Exercise-Induced Pulmonary Vascular Dysfunction After Pulmonary Thromboendarterectomy or Balloon Pulmonary Angioplasty

Recruiting
2
20
US
Adempas, Riociguat
University of Colorado, Denver, Bayer
Chronic Thromboembolic Disease (CTED), Exercise Intolerance Post PEA Surgery
12/24
12/24
CHORUS, NCT06259292: Comprehensive HHT Outcomes Registry of the United States

Recruiting
N/A
10000
US
Cure HHT, Augusta University, The Cleveland Clinic, Mayo Clinic, Massachusetts General Hospital, Columbia University, Oregon Health and Science University, University of California, Los Angeles, University of California, San Francisco, University of Colorado, Denver, University of North Carolina, Chapel Hill, University of Pennsylvania, University of Texas, University of Utah, Washington University School of Medicine, Yale University, Health Resources and Services Administration (HRSA), Children's Hospital of Philadelphia
Hereditary Hemorrhagic Telangiectasia, Arteriovenous Malformations, Telangiectasia, Epistaxis, GastroIntestinal Bleeding, Cerebral Arteriovenous Malformations, Vascular Malformation
11/33
11/33
PHAR, NCT04071327: Pulmonary Hypertension Association Registry

Recruiting
N/A
3000
US
Pulmonary Hypertension Association, Inc., University of Washington, the Collaborative Health Studies Coordinating Center
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
10/25
10/25
O'Bryant, Cindy
NCT02007382: Study of Trametinib in Advanced Cancer Patients With Hepatic Dysfunction

Recruiting
1
68
US, Canada
Trametinib, GSK1120212
University Health Network, Toronto, National Cancer Institute (NCI)
Solid Tumors, Hepatic Dysfunction
06/15
12/15
Reusch, Jane EB
REACH, NCT04791371: Role of Microvascular Insulin Resistance and Cardiorespiratory Fitness Diabetes

Recruiting
N/A
150
US
Cardiovascular exercise
University of Colorado, Denver, University of Virginia, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 2 Diabetes, Overweight and Obesity
09/26
12/27
Cornwell, William K
NCT03409588: Treatment of Exercise-Induced Pulmonary Vascular Dysfunction After Pulmonary Thromboendarterectomy or Balloon Pulmonary Angioplasty

Recruiting
2
20
US
Adempas, Riociguat
University of Colorado, Denver, Bayer
Chronic Thromboembolic Disease (CTED), Exercise Intolerance Post PEA Surgery
12/24
12/24
NCT05349630: Impact of Iron Supplementation on Right Ventricular Function and Exercise Performance in Hypoxia

Not yet recruiting
1
5
US
Ferrous sulfate 325mg
University of Colorado, Denver
Right Ventricular Dysfunction, Hypoxia
12/25
05/26
IRONMAN, NCT03078972: Effect of mechanIcal circulatoRy Support ON Exercise Capacity aMong pAtieNts With Heart Failure

Active, not recruiting
N/A
60
US
University of Colorado, Denver
Heart Failure，Congestive
06/23
06/23
NCT05566483: Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity

Recruiting
N/A
30
US
Exercise
University of Colorado, Denver
Post-acute Sequelae of SARS-CoV-2 Infection
12/23
12/23
NCT05849168: High-Intensity Interval Training to Improve Symptoms of Deployment-Related Respiratory Disease

Completed
N/A
12
US
Exercise training
University of Colorado, Denver, VA Office of Research and Development
Occupational Exposure
07/24
07/24
NCT04147299: Cardiopulmonary and Right Ventricular Function in Health and Disease

Active, not recruiting
N/A
80
US
University of Colorado, Denver
Heart Failure, Athletes Heart
05/25
05/25
Regensteiner, Judy
NCT03419195: Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex

Completed
N/A
124
US
Cardiovascular exercise training, Exercise Training
University of Colorado, Denver, VA Eastern Colorado Health Care System
Type 2 Diabetes Mellitus, Healthy, Overweight, Cardiovascular Risk Factor
03/23
03/23
REACH, NCT04791371: Role of Microvascular Insulin Resistance and Cardiorespiratory Fitness Diabetes

Recruiting
N/A
150
US
Cardiovascular exercise
University of Colorado, Denver, University of Virginia, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 2 Diabetes, Overweight and Obesity
09/26
12/27
Fernandez-Bustamante, Ana
NCT03923556: Sugammadex Versus Neostigmine for Reversal of Neuromuscular Blockade at the End of Kidney Transplantation Surgery

Completed
4
84
US
Sugammadex, Neostigmine
University of Colorado, Denver
Kidney Transplant; Complications, Postoperative Residual Curarization, Postoperative Residual Weakness
09/23
10/23
NCT06239831: Postoperative Respiratory and Activity Monitoring

Recruiting
N/A
30
US
ExSpiron and ActivPAL Monitors
University of Colorado, Denver, Brigham and Women's Hospital
Hypoventilation, Hypoxemia, Postoperative Pulmonary Complications
12/24
06/25
MHALT, NCT03534141: Mild Hypothermia and Acute Kidney Injury in Liver Transplantation

Terminated
N/A
175
US
Esophageal cooling/warming device, EnsoETM, ECD - Esophageal Cooling Device, Mild hypothermia, Normothermia
University of California, San Francisco, University of Colorado, Denver, The Methodist Hospital Research Institute
Cirrhosis, End Stage Liver Disease, Acute Kidney Injury, Liver Transplant; Complications, Chronic Kidney Diseases, Hepatitis c, Hepatitis B, NASH - Nonalcoholic Steatohepatitis, Alcoholic Cirrhosis, Hepatocellular Carcinoma
08/23
09/23
PRIME-AIR, NCT04108130: An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The Study

Recruiting
N/A
750
US
Preoperative Education, Intraoperative PEEP (Positive End-Expiratory Pressure) Individualization, Individualization of Neuromuscular Blockade, Postoperative Incentive Spirometry, Postoperative Ambulation
Columbia University
Postoperative Pulmonary Complications
07/23
07/24
NCT06304493: REMINDers for Incentive Spirometry in PACU (REMIND-IS in PACU)

Completed
N/A
240
US
Alarms, Auditory and visual reminders
University of Colorado, Denver
Postoperative Atelectasis, Postoperative Hypoxemia, Postoperative Pneumonia, Postoperative Pulmonary Complications, Patient Adherence, Incentive Spirometry, Respiratory Therapy, Respiratory Insufficiency
09/24
10/24
Corr, Bradley R
ENGOT-EN20, NCT05611931 / 2022-002540-42: Selinexor in Maintenance Therapy After Systemic Therapy for Participants with P53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma

Jul 2024 - Dec 2024: Top-line data from XPORT-EC trial in participants with TP53 wild type endometrial cancer
Recruiting
3
220
Europe, Canada, US, RoW
Selinexor, KPT-330, Matching Placebo for selinexor
Karyopharm Therapeutics Inc, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Belgium and Luxembourg Gynaecological Oncology Group, North Eastern German Society of Gynaecological Oncology, Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies, Spanish Research Group in Ovarian Cancer, The Central and Eastern European Gynecologic Oncology Group, Israeli Society of Gynecologic Oncology, Australia New Zealand Gynaecological Oncology Group
Endometrial Cancer
01/25
01/28
NRG-GY019, NCT04095364: Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Recruiting
3
450
Europe, Canada, US, RoW
Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Imaging Technique, Diagnostic Imaging Technique, Image Type, Imaging, Imaging (procedure), imaging procedure, Imaging Procedures, imaging type, IMAGING_METHOD, imaging_type, Medical Imaging, Type of imaging, Letrozole, CGS 20267, Femara, Fempro, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat
NRG Oncology, National Cancer Institute (NCI)
Low Grade Fallopian Tube Serous Adenocarcinoma, Ovarian Low Grade Serous Adenocarcinoma, Primary Peritoneal Low Grade Serous Adenocarcinoma, Stage II Fallopian Tube Cancer AJCC v8, Stage II Ovarian Cancer AJCC v8, Stage II Primary Peritoneal Cancer AJCC v8, Stage III Fallopian Tube Cancer AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage III Primary Peritoneal Cancer AJCC v8, Stage IV Fallopian Tube Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Primary Peritoneal Cancer AJCC v8
02/27
02/28
NRG-GY026, NCT05256225: Testing the Addition of Trastuzumab or Trastuzumab/Pertuzumab to the Usual Chemotherapy for HER2 Positive Endometrial Cancer

Recruiting
2/3
525
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, High-Dose-Rate Vaginal Cuff Brachytherapy, HDR-VCB, Hyaluronidase-zzxf/Pertuzumab/Trastuzumab, Pertuzumab and Trastuzumab hyaluronidase, Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf, Pertuzumab/Trastuzumab/Hyaluronidase-zzxf, Phesgo, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, MUGA, Radionuclide Ventriculography, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat, Quality-of-Life Assessment, Quality of Life Assessment, Trastuzumab/Hyaluronidase-oysk, Herceptin Hylecta, Trastuzumab and Hyaluronidase, Trastuzumab and Hyaluronidase-oysk, Trastuzumab and Recombinant Human Hyaluronidase PH20, Trastuzumab and rHuPH20, Trastuzumab-Hyaluronidase-oysk
National Cancer Institute (NCI), NRG Oncology
Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Dedifferentiated Carcinoma, Endometrial Endometrioid Adenocarcinoma, Endometrial Mixed Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Endometrial Undifferentiated Carcinoma, Uterine Corpus Carcinosarcoma
10/27
10/27
NCT03617679: Rucaparib vs Placebo Maintenance Therapy in Metastatic and Recurrent Endometrial Cancer

Active, not recruiting
2
79
US
Rucaparib, Placebo Oral Tablet
University of Colorado, Denver, Clovis Oncology, Inc., National Cancer Institute (NCI)
Metastatic Endometrial Cancer
10/23
12/24
PICCOLO, NCT05041257: Mirvetuximab Soravtansine Monotherapy in Platinum-Sensitive Epithelial, Peritoneal, and Fallopian Tube Cancers

Hourglass Oct 2024 - Dec 2024 : Approval for 2L+ FRα +ve PROC
Hourglass Jan 2024 - Jun 2024 : FDA action date for approval for ovarian cancer with high FRAC
Hourglass Jan 2024 - Jun 2024 : sBLA approval for ovarian cancer
Hourglass Jan 2023 - Dec 2023 : ORR data from PICCOLO trial for platinum sensitive ovarian cancer
Completed
2
79
Europe, Canada, US, RoW
Mirvetuximab soravtansine, MIRV, IMGN853
AbbVie
Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
01/24
12/24
NCT04576104: Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

Recruiting
2
50
US
Biopsy, BIOPSY_TYPE, Bx, Extended Release Metformin Hydrochloride, ER Metformin Hydrochloride, Extended-release Metformin Hydrochloride, Glucophage XR, Glumetza, Metformin Hydrochloride Extended Release, Megestrol Acetate, 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate, 17.alpha.-Acetoxy-6-methylpregna-4,6-diene-3,20-dione, 6-Dehydro-6-methyl-17.alpha.-acetoxyprogesterone, 6-Methyl-6-dehydro-17.alpha.-acetoxyprogesterone, BDH 1298, BDH-1298, Maygace, Megace, Megestat, Megestil, Niagestin, Ovaban, Pallace, SC 10363, SC-10363, Questionnaire Administration
National Cancer Institute (NCI)
Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, Endometrial Carcinoma
11/25
05/26
NCT06388018: Tailoring Therapy in Post-surgical Patients With Low-risk Endometrial Cancer

Recruiting
2
325
US
Clinical Observation, observation, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, External Beam Radiation Therapy, Definitive Radiation Therapy, EBRT, External Beam Radiation, External Beam Radiotherapy, External Beam Radiotherapy (conventional), External Beam RT, external radiation, External Radiation Therapy, external-beam radiation, Radiation, External Beam, Teleradiotherapy, Teletherapy, Teletherapy Radiation, High-Dose-Rate Vaginal Brachytherapy, HDR-IVB, High-Dose-Rate Intra-Vaginal Brachytherapy, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Questionnaire Administration, X-Ray Imaging, Conventional X-Ray, Diagnostic Radiology, Medical Imaging, X-Ray, Plain film radiographs, Radiographic Imaging, Radiographic imaging procedure (procedure), Radiography, RG, Static X-Ray, X-Ray
NRG Oncology, National Cancer Institute (NCI)
Stage I Uterine Corpus Endometrial Stromal Sarcoma AJCC v8, Stage II Uterine Corpus Endometrial Stromal Sarcoma AJCC v8, Stage III Uterine Corpus Endometrial Stromal Sarcoma AJCC v8
01/27
01/27
NCT05327010: Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

Recruiting
2
88
US
BET Bromodomain Inhibitor ZEN-3694, BETi ZEN-3694, ZEN 3694, ZEN-3694, ZEN003694, Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Diagnostic Imaging, Medical Imaging, Talazoparib, BMN 673, BMN-673, BMN673
National Cancer Institute (NCI)
Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm
08/25
08/25
NCT05887609: An Evaluation of Maintenance Therapy Combination Mirvetuximab Soravtansine and Olaparib

Recruiting
2
53
US
Mirvetuximab Soravtansine, IMGN853, MIRV, Olaparib
University of Colorado, Denver, ImmunoGen, Inc.
Ovary Cancer, Peritoneal Cancer, Fallopian Tube Cancer
04/26
12/27
GOG-3088, NCT05649956: Letrozole in Uterine Leiomyosarcoma

Recruiting
2
40
US
Letrozole
GOG Foundation
Uterine Leiomyosarcoma
07/28
07/29
CCTG EN10, NCT05640999: Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

Recruiting
2
325
Europe, Canada, US, RoW
Vaginal brachytherapy, Adjuvant radiotherapy (EBRT +/- brachytherapy), Observation
Canadian Cancer Trials Group, Canadian Cancer Clinical Trials Network
Endometrial Cancer
12/28
06/29
NRG-GY028, NCT05538897: Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers

Recruiting
1/2
96
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Ipatasertib, GDC 0068, GDC-0068, GDC0068, RG 7440, RG-7440, RG7440, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Megestrol Acetate, 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate, 17.alpha.-Acetoxy-6-methylpregna-4,6-diene-3,20-dione, 6-Dehydro-6-methyl-17.alpha.-acetoxyprogesterone, 6-Methyl-6-dehydro-17.alpha.-acetoxyprogesterone, BDH 1298, BDH-1298, Maygace, Megace, Megestat, Megestil, Niagestin, Ovaban, Pallace, SC 10363, SC-10363
National Cancer Institute (NCI), NRG Oncology
FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma, Metastatic Endometrial Endometrioid Adenocarcinoma, Recurrent Endometrial Endometrioid Adenocarcinoma
01/27
01/27
IMGN151-1001, NCT05527184: First in Human Study of IMGN151 in Recurrent Gynaecological Cancers

Recruiting
1
423
US
IMGN151
AbbVie
Endometrial Cancer, High Grade Serous Adenocarcinoma of Ovary, Primary Peritoneal Carcinoma, Fallopian Tube Cancer, Cervical Cancer
02/27
02/27
NCT04092270: A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer

Active, not recruiting
1
54
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNV Scan, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Pegylated Liposomal Doxorubicin Hydrochloride, ATI-0918, Caelyx, Dox-SL, Doxil, Doxilen, Doxorubicin HCl Liposomal, Doxorubicin HCl Liposome, Doxorubicin Hydrochloride Liposome, Duomeisu, Evacet, LipoDox, Lipodox 50, Liposomal Adriamycin, Liposomal Doxorubicin Hydrochloride, Liposomal-Encapsulated Doxorubicin, Pegylated Doxorubicin HCl Liposome, Pegylated Liposomal Doxorubicin, S-Liposomal Doxorubicin, Stealth Liposomal Doxorubicin, TLC D-99, Peposertib, 3-Pyridazinemethanol, alpha-(2-Chloro-4-fluoro-5-(7-(4-morpholinyl)-4-quinazolinyl)phenyl)-6-methoxy-, (alphaS)-, M 3814, M-3814, M3814, MSC 2490484A, MSC-2490484A, MSC2490484A, Nedisertib
National Cancer Institute (NCI)
Endometrial High Grade Endometrioid Adenocarcinoma, Fallopian Tube Carcinosarcoma, Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube High Grade Serous Adenocarcinoma, Fallopian Tube Mucinous Adenocarcinoma, Fallopian Tube Transitional Cell Carcinoma, Fallopian Tube Undifferentiated Carcinoma, FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma, Ovarian High Grade Serous Adenocarcinoma, Ovarian Seromucinous Carcinoma, Ovarian Undifferentiated Carcinoma, Platinum-Sensitive Ovarian Carcinoma, Primary Peritoneal Carcinosarcoma, Primary Peritoneal High Grade Serous Adenocarcinoma, Primary Peritoneal Transitional Cell Carcinoma, Primary Peritoneal Undifferentiated Carcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Low Grade Fallopian Tube Serous Adenocarcinoma, Recurrent Ovarian Carcinoma, Recurrent Ovarian Carcinosarcoma, Recurrent Ovarian Clear Cell Adenocarcinoma, Recurrent Ovarian Endometrioid Adenocarcinoma, Recurrent Ovarian Low Grade Serous Adenocarcinoma, Recurrent Ovarian Mucinous Adenocarcinoma, Recurrent Ovarian Transitional Cell Carcinoma, Recurrent Primary Peritoneal Carcinoma, Recurrent Primary Peritoneal Low Grade Serous Adenocarcinoma
06/25
06/25
NRG-GY022, NCT03997370: Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol

Recruiting
1
350
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Iohexol, Omnipaque
NRG Oncology, National Cancer Institute (NCI)
Malignant Solid Neoplasm
02/27
02/28
Rafferty, Deirdre
REACH, NCT04791371: Role of Microvascular Insulin Resistance and Cardiorespiratory Fitness Diabetes

Recruiting
N/A
150
US
Cardiovascular exercise
University of Colorado, Denver, University of Virginia, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 2 Diabetes, Overweight and Obesity
09/26
12/27
MORROW, MARK
NCT03409016: Biomarkers of Immune-Related Toxicity

Recruiting
N/A
69
US
Blood Testing
University of Colorado, Denver, Cancer League of Colorado
Cancer, Metastatic Cancer
05/25
05/27
Sottile, Peter
NCT03409588: Treatment of Exercise-Induced Pulmonary Vascular Dysfunction After Pulmonary Thromboendarterectomy or Balloon Pulmonary Angioplasty

Recruiting
2
20
US
Adempas, Riociguat
University of Colorado, Denver, Bayer
Chronic Thromboembolic Disease (CTED), Exercise Intolerance Post PEA Surgery
12/24
12/24
Cree-Green, Melanie
RESTORE, NCT05819853: Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome

Recruiting
3
80
US
Semaglutide Injectable Product (Wegovy and/or Ozempic), Semaglutide (Wegovy and/or Ozempic)
University of Colorado, Denver, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Obese
02/28
06/28
TEAL, NCT03919929: Treating PCOS With Semaglutide vs Active Lifestyle Intervention

Active, not recruiting
2/3
60
US
Semaglutide 3mg and 7mg [Rybelsus], GLP-1 receptor agonist, Weight loss diet
University of Colorado, Denver, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
PCOS, Adolescent Obesity, NAFLD
07/24
07/24
MANGO, NCT03587727: Hepatic Mitochondrial Function in Youth

Active, not recruiting
N/A
19
US
University of Colorado, Denver
Hepatic Steatosis, Bariatric Surgery Candidate, Adolescent Obesity, Obesity
06/24
06/24
Forsberg, Peter
NCT04925193: Personalized Selinexor-based Therapy for Relapsed/Refractory Multiple Myeloma

Active, not recruiting
2
18
US
Selinexor, Pomalidomide, Daratumumab, Carfilzomib, Dexamethasone
University of Colorado, Denver, Karyopharm Therapeutics Inc, National Cancer Institute (NCI)
Multiple Myeloma in Relapse
08/24
11/25
iinnovate-2, NCT05556616 / 2022-001418-20: A Study of Modakafusp Alfa in Adult Participants With Multiple Myeloma

Completed
1
15
Europe, US, RoW
Modakafusp alfa, TAK-573, Lenalidomide, Bortezomib, Carfilzomib, Daratumumab, Pomalidomide
Takeda, Takeda Development Center Americas, Inc.
Multiple Myeloma
06/24
06/24
20-1319.cc, NCT05287568: CC-486 and Venetoclax for Acute Myeloid Leukemia

Recruiting
1
35
US
Venetoclax, ABT-199, Abbvie, CC-486
University of Colorado, Denver, Bristol-Myers Squibb
AML
03/27
03/29
Tytus, Hannah
IO-202-CL-001, NCT04372433: IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML

Active, not recruiting
1
106
US
IO-202, IO-202 and Azacitidine, IO-202 and AZA, IO-202 and Azacitidine + Venetoclax, IO-202 and AZA + Ven
Immune-Onc Therapeutics, California Institute for Regenerative Medicine (CIRM)
AML With Monocytic Differentiation, CMML
01/26
01/27
Tansksley, Heather
NCT04796506: Slow Wave Sleep As a Biomarker of Rehabilitation-induced Cognitive Improvement in PD

Recruiting
N/A
120
US
Progressive Resistance Training (PRT), PRT, Delayed Exercise Training (DE), Endurance Training (ET), ET
University of Colorado, Denver, National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Parkinson Disease
03/26
03/26
Sleyster, Madison
NCT04796506: Slow Wave Sleep As a Biomarker of Rehabilitation-induced Cognitive Improvement in PD

Recruiting
N/A
120
US
Progressive Resistance Training (PRT), PRT, Delayed Exercise Training (DE), Endurance Training (ET), ET
University of Colorado, Denver, National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Parkinson Disease
03/26
03/26
Iorio, Matt
NCT06631924: Intramedullary Fixation for Metacarpal Fractures: A Prospective Study Comparing Outcomes

Completed
N/A
40
US
Implant
University of Colorado, Denver
Metacarpal Fracture
04/24
04/24
Vondran, Kayla
PRISM-MEL-301, NCT06112314: IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma

Recruiting
3
680
Europe, US, RoW
Brenetafusp, IMC-F106C, Nivolumab, OPDIVO, Nivolumab + Relatlimab, OPDUALAG
Immunocore Ltd
Advanced Melanoma
10/27
10/27

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