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 26 Trials 
50 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Los, M
CAIRO5, NCT02162563 / 2013-005435-24: Treatment Strategies in Colorectal Cancer Patients with Initially Unresectable Liver-only Metastases

Completed
3
530
Europe
FOLFOX/ FOLFIRI with bevacizumab, - bevacizumab, - irinotecan, - leucovorin, - 5-fluorouracil, - oxaliplatin, FOLFOXIRI with bevacizumab, FOLFOX/ FOLFIRI with panitumumab, - panitumumab
Dutch Colorectal Cancer Group
Colorectal Cancer, Liver Metastases
07/22
01/25
NCT02301286: A Trial of Aspirin on Recurrence and Survival in Colon Cancer Patients

Active, not recruiting
3
770
Europe
Acetylsalicylic acid, Aspirin, Placebo Acetylsalicylic acid, Placebo
Leiden University, Stichting voor Patienten met Kanker aan het Spijsverteringskanaal (SPKS), Dutch Colorectal Cancer Group, Stichting Geriatrische Oncologie Nederland (GeriOnNe), Fonds NutsOhra, Innovatiefonds Zorgverzekeraars
Colon Cancer, Adjuvant Therapy
12/27
12/27
LyRICX, NCT03764553: Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric Cancer

Recruiting
2
320
Europe
Liposomal Irinotecan, Carboplatin, Capecitabine, Xeloda, Oxaliplatin, 5-fluorouracil, Leucovorin
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Servier
Esophageal Cancer
07/25
07/26
DRUP, NCT02925234 / 2015-004398-33: The Drug Rediscovery Protocol ( Trial)

Recruiting
2
1550
Europe
Panitumumab, Vectibix, Olaparib, Lynparza, Dabrafenib, Tafinlar, Nilotinib, Tasigna, Trametinib, Mekinist, Erlotinib, Tarceva, Trastuzumab and Pertuzumab (combination treatment), Herceptin + Perjeta, Vemurafenib and Cobimetinib (combination treatment), Zelboraf + Cotellic, Vismodegib, Erivedge, Regorafenib, Stivarga, Nivolumab, Opdivo, Afatinib, Giotrif, Dabrafenib and trametinib, Tafinlar and Mekinist, Ribociclib, Kisqali, Lenvatinib, Lenvima, Pembrolizumab, Keytruda, Durvalumab, MEDI4736, Rucaparib, Rubraca, Axitinib, Inlyta, Palbociclib, Ibrance, Crizotinib, Xalkori, Sunitinib, Sutent, Cabozantinib, Cabometyx, Abemaciclib, Verzenios, Alectinib, Alecensa, Atezolizumab and Bevacizumab, Tecentriq and Avastin, Ipilimumab and nivolumab, Yervoy and Opdivo, Entrectinib, Rozlytrek, Talazoparib, Talzenna, Dacomitinib, Vizimpro, Lorlatinib, Lorviqua, Erdafitinib, Balversa, Alpelisib, Piqray, Niraparib, Zejula, Pemigatinib, Pemazyre, Selpercatinib, Retsevmo, Tepotinib, Tepmetko
The Netherlands Cancer Institute, Amgen, AstraZeneca, Bayer, Bristol-Myers Squibb, Novartis, Roche Pharma AG, Merck Sharp & Dohme LLC, Boehringer Ingelheim, Ipsen, Eisai Inc., Pfizer, Clovis Oncology - Pharma and, Eli Lilly and Company, Janssen, LP, GlaxoSmithKline, Incyte Corporation, Dutch Cancer Society, Stelvio for Life
Cancer, Tumors, Neoplasm, Neoplasia
09/27
12/27
CrEATE, NCT06434896: Circulating Tumor DNA Based Adjuvant Chemotherapy in Stage II Colon Cancer Patients: the MEDOCC- Trial

Recruiting
N/A
1320
Europe
ctDNA analysis after surgery
UMC Utrecht, Personal Genome Diagnostics (PGDx), The Netherlands Cancer Institute
Circulating Tumor DNA, Recurrence, Colon Cancer Stage II
03/35
03/35
ORCHESTRA, NCT01792934: Chemotherapy and Maximal Tumor Debulking of Multi-organ Colorectal Cancer Metastases

Recruiting
N/A
478
Europe
XELOX regimen according to standard procedures, FOLFOX regimen according to standard procedures, Surgery, radiofrequency ablation (RFA), transarterial chemo-embolization using irinotecan drug-eluted beads ((DEBIRI-)TACE), stereotactic body radiation therapy (SBRT), Bevacizumab, tumor biopsy
Radboud University Medical Center, Erasmus Medical Center
Multi-organ Metastatic Colorectal Cancer
07/23
07/25
PLCRC, NCT02070146: Prospective Data Collection Initiative on Colorectal Cancer

Recruiting
N/A
50000
Europe
Dutch Colorectal Cancer Group
Colorectal Cancer
01/50
01/51
Hilbrands, Luuk
OPTIMIZE, NCT03797196: RCT Comparing Immunosuppressive Regimens in Elderly Renal Transplant Recipients

Active, not recruiting
4
374
Europe
low dose tacrolimus in combination with everolimus, standard dose tacrolimus with mycophenolate mofetil
University Medical Center Groningen, Radboud University Medical Center, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Amsterdam UMC, location VUmc, UMC Utrecht, Leiden University Medical Center, Erasmus Medical Center, Universitaire Ziekenhuizen KU Leuven
Renal Transplant Recipients, Elderly Patients, Immunosuppression
06/25
12/26
Borst, Gert Jan de
NCT02229370: Carotid Aneurysm Registry

Recruiting
N/A
500
Europe
UMC Utrecht
Extracranial Carotid Artery Aneurysm
06/19
12/25
NCT05828576: ECAA Brain MRI: Seeking the Link Between Extracranial Carotid Artery Aneurysms and Small Vessel Disease

Recruiting
N/A
50
Europe
MRI
UMC Utrecht
Extracranial Carotid Artery Aneurysm
04/25
04/25
Voskuil, Michiel
NCT04280029: SELUTION SLR™ 014 In-stent Restenosis

Active, not recruiting
N/A
418
Europe, Canada, US, RoW
SELUTION SLR™ DEB, Control
M.A. Med Alliance S.A., Iqvia Pty Ltd, Cordis Corporation
Coronary Restenosis
07/25
08/29
LANDMARK, NCT04275726: Trial: a Randomised Controlled Trial of Myval THV

Recruiting
N/A
768
Europe, RoW
Myval THV Series, Myval/Myval Inception THVs or any subsequent advanced version commercially available at the study site., Contemporary Valves (Sapien THV Series and Evolut THV Series), Sapien THV Series (Sapien 3/Sapien 3 Ultra THVs) and Evolut THV Series (Evolut R/Evolut PRO THVs ) or any subsequent advanced version commercially available at the study site.
Meril Life Sciences Pvt. Ltd.
Aortic Valve Stenosis
03/24
12/33
PRO-TAVI, NCT05078619: Percutaneous Coronary Intervention Before Transcatheter Aortic Valve Implantation

Active, not recruiting
N/A
466
Europe
No PCI
UMC Utrecht, ZonMw: The Netherlands Organisation for Health Research and Development
Valvular Heart Disease, Aortic Valve Stenosis, Coronary Artery Disease
12/25
12/29
iCORONARY, NCT04939207: Safety and Cost-efficiëncy of New Imaging Techniques in Patients Suspected of Coronary Artery Disease

Recruiting
N/A
825
Europe
CT-FFR, Angiography-derived FFR, Angiography with invasive FFR-measurements
St. Antonius Hospital, ZonMw: The Netherlands Organisation for Health Research and Development, UMC Utrecht
Coronary Artery Disease
04/25
04/25
FAST III, NCT04931771: Fractional Flow Reserve or 3D-Quantitative-Coronary-Angiography Based Vessel-FFR Guided Revascularization

Recruiting
N/A
2228
Europe
vFFR guided revascularization, FFR guided revascularization
ECRI bv, Siemens Healthineers AG, Pie Medical Imaging
Coronary Artery Disease
05/25
05/25
VISTA, NCT06008080: Post-Market Clinical Follow Up Study with Navitor Valve

Recruiting
N/A
1000
Europe, Japan
Navitor Transcatheter Aortic Valve, FlexNav Delivery System, Navitor Loading System
Abbott Medical Devices
Aortic Stenosis
01/26
12/30
Arends, Joop
SELFIE, NCT04004299: Self-testing for HCV Re-infection in MSM

Recruiting
N/A
200
Europe
HCV RNA self-test
Erasmus Medical Center
Hepatitis C Recurrent, HIV-1-infection
02/23
06/23
Koornstra, R HT
Triple-B, NCT01898117 / 2013-001484-23: Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Atezolizumab as First-line Treatment in Advanced Triple Negative Breast Cancer

Active, not recruiting
2
304
Europe
Carbo/cyclo, Carboplatin, Cyclophosphamide, Carbo/cyclo + atezolizumab, Atezolizumab, Paclitaxel, Paclitaxel + Atezolizumab
The Netherlands Cancer Institute, Borstkanker Onderzoek Groep, Roche Pharma AG
Breast Cancer
12/24
12/30
AMICO, NCT04754672: Aerobic Fitness or Muscle Mass Training to Improve Colorectal Cancer Outcome

Recruiting
N/A
228
Europe
Continuous aerobic and resistance exercise intervention, AE+RE, Continuous aerobic and aerobic interval exercise intervention, AE+AI
Radboud University Medical Center, UMC Utrecht, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Rijnstate Hospital, Jeroen Bosch Ziekenhuis, Flevoziekenhuis, Catharina Ziekenhuis Eindhoven, Meander Medical Center, Ziekenhuis Amstelland, Amphia Hospital, Spaarne Gasthuis, Canisius-Wilhelmina Hospital, Amsterdam UMC, location VUmc, The Netherlands Cancer Institute
Colorectal Cancer, Chemotherapeutic Toxicity, Survivorship, Lifestyle
03/26
12/26
Oldenburg, Bas
HELIOS, NCT04291976: Back-to-back Endoscopy Versus Single-pass Endoscopy and Chromoendoscopy in IBD Surveillance

Completed
N/A
563
Europe
Back-to-back high-definition white light endoscopy, single-pass high-definition white light endoscopy, chromoendoscopy
Radboud University Medical Center, UMC Utrecht, Leiden University Medical Center, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Inflammatory Bowel Diseases, Colorectal Neoplasms
05/23
11/23
Spiering, Wilko
NCT06153693: Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension

Active, not recruiting
3
1083
Europe, Canada, US, RoW
Placebo, lorundrostat Dose 1, lorundrostat Dose 2
Mineralys Therapeutics Inc.
Hypertension
12/24
02/25
TEMP-PREVENT, NCT05832580: The Prevention of Systemic Ectopic Mineralization in Pseudoxanthoma Elasticum

Recruiting
3
76
Europe
Etidronate, Placebo
UMC Utrecht
Pseudoxanthoma Elasticum
03/27
04/27
NCT04981470: The Baroloop Study

Terminated
N/A
4
Europe
baroloop System
neuroloop GmbH, MAXIS GmbH
Hypertension
10/23
10/23
CALM-DIEM, NCT02827032: Controlling and Lowering Blood Pressure With the MobiusHD™

Recruiting
N/A
200
Europe
MobiusHD™
Vascular Dynamics, Inc.
Hypertension
12/24
06/26
Hulsker, Caroline
APAC, NCT02848820 / 2016-003052-70: Initial Non-operative Treatment Strategy Versus Appendectomy Treatment Strategy for Simple Appendicitis in Children

Active, not recruiting
4
302
Europe
Augmentin + Gentamicin, Amoxicillin/clavulanic acid (Augmentin) + Gentamicin, Appendectomy
Ramon Gorter, ZonMw: The Netherlands Organisation for Health Research and Development, Amsterdam UMC, location VUmc
Appendicitis
12/24
12/24
Minnema, Monique
EMN22, NCT04131309 / 2018-004333-33: A Study of Daratumumab Monotherapy in Previously Untreated Patients With Stage 3B Light Chain (AL) Amyloidosis

Active, not recruiting
2
40
Europe
Daratumumab, Bortezomib Injection, velcade, Dexamethasone oral tablet
Stichting European Myeloma Network, Janssen Pharmaceutica
Light Chain (AL) Amyloidosis, Stage 3B
01/25
01/25
EMN27, NCT04617925 / 2020-004001-32: A Study of Belantamab Mafodotin in Patients With Relapsed or Refractory AL Amyloidosis

Active, not recruiting
2
35
Europe
Belantamab mafodotin
Stichting European Myeloma Network, GlaxoSmithKline
AL Amyloidosis
07/25
07/25
DREAMM 5, NCT04126200 / 2019-001138-32: Platform Study of Belantamab Mafodotin as Monotherapy and in Combination With Anti-cancer Treatments in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

Hourglass Jul 2021 - Dec 2021 : From DREAMM-5 trial in combination with nirogacestat for r/r multiple myeloma
Hourglass Feb 2020 - Mar 2020 : Initiation of P1b sub-study of P2 DREAMM-5 trial in combination with nirogacestat for relapsed/refractory multiple myeloma
Checkmark From DREAMM 5 trial in R/R multiple myeloma patients at ASH 2019
Nov 2019 - Nov 2019: From DREAMM 5 trial in R/R multiple myeloma patients at ASH 2019
Checkmark Initiation of DREAMM-5 trial in r/r multiple myeloma
More
Active, not recruiting
2
209
Europe, Canada, US, RoW
Belantamab mafodotin, GSK3174998, Feladilimab, Nirogacestat, Dostarlimab, Isatuximab, Lenalidomide, Dexamethasone, Pomalidomide
GlaxoSmithKline
Multiple Myeloma
02/29
02/29
EUREKA, NCT06205953: A EUropean REgistry and Sample Sharing networK to Promote the Diagnosis and Management of Light Chain Amyloidosis

Recruiting
N/A
400
Europe, RoW
Fondazione IRCCS Policlinico San Matteo di Pavia
AL Amyloidosis
06/26
06/26
Klaassen, Ingrid
CALM-DIEM, NCT02827032: Controlling and Lowering Blood Pressure With the MobiusHD™

Recruiting
N/A
200
Europe
MobiusHD™
Vascular Dynamics, Inc.
Hypertension
12/24
06/26
Intven, Martijn
SIRIUS, NCT05375708: Systemic Therapy in Combination With Stereotactic Radiotherapy in Patients With Metastatic Colorectal Cancer up to 10 Metastatic Sites

Not yet recruiting
2
93
Europe
Stereotactic body radiation therapy (SBRT), Maintenance therapy (CAP-B or 5-FU/LV plus bevacizumab.)
UMC Utrecht
Metastatic Colorectal Cancer, Oligometastatic Disease
06/28
06/28
NCT03426397: "Wait-and-see" Policy for Complete Responders After Chemoradiotherapy for Rectal Cancer

Recruiting
N/A
220
Europe
The Netherlands Cancer Institute, Dutch Cancer Society
Rectal Neoplasms
06/21
06/26
PANCOSAR, NCT05265663: Stereotactic Radiotherapy vs Best Supportive Care in Unfit Pancreatic Cancer Patients

Recruiting
N/A
98
Europe
stereotactic ablative radiotherapy
VU University Medical Center, UMC Utrecht, Erasmus Medical Center, Dutch Cancer Society, Viewray Inc.
Pancreatic Cancer Non-resectable
03/24
06/24
STRONGII, NCT06493734: Stereotactic Body Radiation Therapy After Chemotherapy for Unresectable Perihilar Cholangiocarcinoma

Recruiting
N/A
30
Europe
Stereotactic body radiation therapy
Erasmus Medical Center, Dutch Cancer Society
Klatskin Tumor
12/27
03/28
Heijden, Jeroen van der
COMPARE-LAAO, NCT04676880: Left Atrial Appendage Occlusion for AF Patients Unable to Use Oral Anticoagulation Therapy

Active, not recruiting
N/A
609
Europe
Left atrial appendage occlusion (Watchman FLX or Amplatzer Amulet), Watchman FLX device, Amplatzer Amulet device
R&D Cardiologie, ZonMw: The Netherlands Organisation for Health Research and Development
Atrial Fibrillation, Anticoagulants and Bleeding Disorders
05/26
11/26
Zuilen, Arjan Van
OPTIMIZE, NCT03797196: RCT Comparing Immunosuppressive Regimens in Elderly Renal Transplant Recipients

Active, not recruiting
4
374
Europe
low dose tacrolimus in combination with everolimus, standard dose tacrolimus with mycophenolate mofetil
University Medical Center Groningen, Radboud University Medical Center, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Amsterdam UMC, location VUmc, UMC Utrecht, Leiden University Medical Center, Erasmus Medical Center, Universitaire Ziekenhuizen KU Leuven
Renal Transplant Recipients, Elderly Patients, Immunosuppression
06/25
12/26
EFFECT-KTx, NCT03769441 / 2018-002571-18: Effect of Ferric Carboxymaltose on Exercise Capacity After Kidney Transplantation

Completed
3
148
Europe
Ferric carboxymaltose, Sodium chloride, Placebo
University Medical Center Groningen, Dutch Kidney Foundation, Vifor Fresenius Medical Care Renal Pharma
Iron-deficiency, Transplant-Related Disorder
08/24
08/24
PROCARE2, NCT05140018: Incidence, Course and Outcome of ABMR in Kidney Transplantation

Recruiting
N/A
225
Europe
Kidney Transplantation, Immunosuppression, Nephrectomy (kidney donation)
University Medical Center Groningen, Dutch Kidney Foundation, UMC Utrecht, Leiden University Medical Center, Maastricht University Medical Center, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Erasmus Medical Center, Radboud University Medical Center
Antibody-mediated Rejection, Kidney Transplantation, Immunosuppression
01/25
03/26
Doormaal, van
ENCASE II, NCT04086550: Evaluate the Safety and Efficacy of Dura Sealant Patch in Reducing CSF Leakage Following Elective Cranial Surgery

Completed
N/A
228
Europe, US
LIQOSEAL, DuraSeal, Adherus
Polyganics BV
Cerebrospinal Fluid Leak
02/24
02/24
Graeff, A de
Triple-B, NCT01898117 / 2013-001484-23: Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Atezolizumab as First-line Treatment in Advanced Triple Negative Breast Cancer

Active, not recruiting
2
304
Europe
Carbo/cyclo, Carboplatin, Cyclophosphamide, Carbo/cyclo + atezolizumab, Atezolizumab, Paclitaxel, Paclitaxel + Atezolizumab
The Netherlands Cancer Institute, Borstkanker Onderzoek Groep, Roche Pharma AG
Breast Cancer
12/24
12/30
Mohammad, N Haj
LyRICX, NCT03764553: Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric Cancer

Recruiting
2
320
Europe
Liposomal Irinotecan, Carboplatin, Capecitabine, Xeloda, Oxaliplatin, 5-fluorouracil, Leucovorin
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Servier
Esophageal Cancer
07/25
07/26
AuspiCiOus, NCT05177133: Anti-PD-1 and CapOx for the First-line Treatment of dMMR Esophagogastric Cancer

Recruiting
2
25
Europe
Capecitabine, Xeloda, Oxaliplatin, Oxaliplatin Accord, Retifanlimab, INCMGA00012
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Incyte Corporation
Gastric Adenocarcinoma, Esophageal Adenocarcinoma
05/25
11/29
Gort
CICILIA, NCT04260529 / 2019-003317-33: CyPep-1 Injections in Cancer Inducing Lymphocyte Infiltrate Accumulations

Completed
1/2
60
Europe
CyPep-1, Pembrolizumab 25 MG/ML [KEYTRUDA®], KEYTRUDA®
Cytovation AS, Merck Sharp & Dohme LLC
Advanced Solid Tumor Malignancy
07/24
07/24
Roodhart, J
AMICO, NCT04754672: Aerobic Fitness or Muscle Mass Training to Improve Colorectal Cancer Outcome

Recruiting
N/A
228
Europe
Continuous aerobic and resistance exercise intervention, AE+RE, Continuous aerobic and aerobic interval exercise intervention, AE+AI
Radboud University Medical Center, UMC Utrecht, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Rijnstate Hospital, Jeroen Bosch Ziekenhuis, Flevoziekenhuis, Catharina Ziekenhuis Eindhoven, Meander Medical Center, Ziekenhuis Amstelland, Amphia Hospital, Spaarne Gasthuis, Canisius-Wilhelmina Hospital, Amsterdam UMC, location VUmc, The Netherlands Cancer Institute
Colorectal Cancer, Chemotherapeutic Toxicity, Survivorship, Lifestyle
03/26
12/26
May, A
AMICO, NCT04754672: Aerobic Fitness or Muscle Mass Training to Improve Colorectal Cancer Outcome

Recruiting
N/A
228
Europe
Continuous aerobic and resistance exercise intervention, AE+RE, Continuous aerobic and aerobic interval exercise intervention, AE+AI
Radboud University Medical Center, UMC Utrecht, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Rijnstate Hospital, Jeroen Bosch Ziekenhuis, Flevoziekenhuis, Catharina Ziekenhuis Eindhoven, Meander Medical Center, Ziekenhuis Amstelland, Amphia Hospital, Spaarne Gasthuis, Canisius-Wilhelmina Hospital, Amsterdam UMC, location VUmc, The Netherlands Cancer Institute
Colorectal Cancer, Chemotherapeutic Toxicity, Survivorship, Lifestyle
03/26
12/26
Schreuder, HWR
OVHIPEC-2, NCT03772028 / 2018-003346-17: Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Recruiting
3
538
Europe, US
cisplatin
The Netherlands Cancer Institute
Ovarian Cancer
04/25
04/26
Schreuder, Henk
CisCon, NCT05406674: Body Surface Area-based vs Concentration-based Dosing of Cisplatin for Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Women With Advanced Ovarian Cancer

Recruiting
2
40
Europe
Cisplatin 100 mg/m2, LO1XA, NDC 16729-288, SUB07483MIG, PL 20075/0123, Cisplatin 40 mg/l
The Netherlands Cancer Institute
FIGO Stage III Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Carcinoma
12/24
12/24
Muijs, Christina
MODELS, NCT06366828: Prediction Models for Complications After CRT in Esophageal Cancer

Recruiting
N/A
2000
Europe
retrospective
University Medical Center Groningen, Dutch Cancer Society, Comprehensive Cancer Centre The Netherlands, Dutch Institute for Clinical Auditing (DICA), ZorgTTP
The Aim of This Project is to Develop and Validate NTCP-models for Complications After nCRT (and Surgical Resection)
06/25
06/30
Boer, Laura S
DYS-CBAS, NCT06618742: Focal Cryoballoon Ablation for Malignant Dysphagia

Recruiting
N/A
20
Europe
Cryotherapy, cryoballoon ablation
Laura Boer
Dysphagia, Esophageal Cancer, Cryotherapy
07/25
12/25
Jong, WK de
ADOPT-lung, NCT06284317: A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients with Early-stage, Operable, Non-small Cell Lung Cancer.

Recruiting
3
290
Europe, RoW
Adjuvant durvalumab
ETOP IBCSG Partners Foundation, AstraZeneca AG Switzerland
Non Small Cell Lung Cancer
10/29
03/30

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