| Feng, Sandy |
| Recruiting | 2 | 340 | US | Everolimus, Zortress, Tacrolimus (continued reduction), FK-506, FR-900506, Prograf, Prograft, Tacrolimus (maintain 50% reduction) | National Institute of Allergy and Infectious Diseases (NIAID) | Liver Transplant | 06/27 | 06/29 | | |
NCT04803006: A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PANORAMA) |
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| Recruiting | 2 | 18 | US | TCD601 | ITB-Med LLC | Kidney Transplantation | 07/27 | 07/30 | | |
| Terminated | 1/2 | 42 | US | arTreg, donor alloantigen-reactive regulatory T cells, CD4+CD25+CD127[lo] Treg cells, leukapheresis, apheresis, cyclophosphamide, Cytoxan®, CTX, mesna, Mesnex®, everolimus, EVR, Afinitor®, Zortress® | National Institute of Allergy and Infectious Diseases (NIAID), Immune Tolerance Network (ITN), PPD, Rho Federal Systems Division, Inc. | Liver Transplant | 03/23 | 03/23 | | |
NCT05215288: Expanded Access for Use of ExoFlo in Abdominal Solid Organ Transplant Patients |
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| No Longer Available | N/A | 20 | US | ExoFlo | Direct Biologics, LLC | Solid Organ Transplant Rejection, Organ Rejection Transplants, Organ Rejection | | | | |
| Recruiting | N/A | 300 | Europe, Canada, US, RoW | liver biopsy | University of Alberta | Liver Dysfunction | 12/25 | 12/26 | | |
| Lightner, Amy L |
NCT05354141: Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS) |
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| Recruiting | 3 | 970 | US | ExoFlo, Intravenous normal saline | Direct Biologics, LLC | Acute Respiratory Distress Syndrome, ARDS | 03/25 | 08/25 | | |
NCT04519697: Mesenchymal Stem Cells for the Treatment of Rectovaginal Fistulas in Participants With Crohn's Disease |
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| Recruiting | 1/2 | 40 | US | Mesenchymal Stem Cells, Placebo | Amy Lightner | Rectovaginal Fistula, Crohn Disease, Crohn Disease of Vulva, Rectolabial; Fistula | 10/22 | 10/22 | | |
IPAAF, NCT04519684: Study of Mesenchymal Stem Cells for the Treatment of Ileal Pouch Fistula's in Participants With Crohn's Disease |
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| Recruiting | 1/2 | 40 | US | Mesenchymal stem cells, Placebo | Amy Lightner | Ileal Pouch, Crohn Disease | 10/22 | 10/22 | | |
NCT04519671: Mesenchymal Stem Cells for the Treatment of Perianal Fistulizing Crohn's Disease |
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| Recruiting | 1/2 | 40 | US | Mesenchymal Stem Cells, Placebo | Amy Lightner | Perianal Crohn Disease, Perianal Fistula, Crohn Disease | 11/22 | 11/22 | | |
NCT04548583: Study of Mesenchymal Stem Cells for the Treatment of Medically Refractory Crohn's Colitis |
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| Recruiting | 1/2 | 24 | US | Remestemcel-L, Placebo | The Cleveland Clinic, Mesoblast, Inc. | Crohn Colitis | 10/23 | 10/23 | | |
NCT04543994: Study of Mesenchymal Stem Cells for the Treatment of Medically Refractory Ulcerative Colitis (UC) |
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| Recruiting | 1/2 | 24 | US | Remestemcel-L, Placebo | The Cleveland Clinic, Mesoblast, Inc. | Ulcerative Colitis | 11/23 | 11/23 | | |
NCT05116761: ExoFlo™ Infusion for Post-Acute COVID-19 and Chronic Post-COVID-19 Syndrome |
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| Withdrawn | 1/2 | 60 | NA | Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles, Saline | Direct Biologics, LLC | Covid19, Postviral Syndrome, Dyspnea | 11/24 | 12/24 | | |
NCT05075811: Study of Ossium Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in the Setting of Crohn's Disease |
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| Recruiting | 1/2 | 20 | US | Ossium vBM-MSC, Ossium Vertebral Bone Marrow Derived Mesenchymal Stem Cells, Placebo | Amy Lightner, Ossium Health, Inc. | Pouch, Ileal, Fistula | 11/24 | 11/24 | | |
NCT05836883: Study of ExoFlo for the Treatment of Perianal Fistulas |
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| Active, not recruiting | 1/2 | 36 | US | ExoFlo, Local injection of normal saline | Direct Biologics, LLC | Perianal Fistula, Crohn's Disease | 12/24 | 12/24 | | |
EXIT-ARDS, NCT05127122: Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles Infusion Treatment for ARDS |
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| Withdrawn | 1/2 | 81 | NA | Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles, ExoFlo, Saline | Direct Biologics, LLC | ARDS, Human | 12/24 | 12/24 | | |
NCT04791878: Study of Mesenchymal Stem Cells for Pediatric Perianal Fistulizing Crohn's Disease |
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| Recruiting | 1 | 10 | US | Mesenchymal stem cells | Amy Lightner | Perianal Fistula Due to Crohn's Disease (Disorder) | 04/23 | 04/23 | | |
NCT05176366: Study of ExoFlo for the Treatment of Medically Refractory Ulcerative Colitis |
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| Active, not recruiting | 1 | 10 | US | ExoFlo | Direct Biologics, LLC | Ulcerative Colitis, Inflammatory Bowel Diseases | 12/24 | 12/24 | | |
NCT05130983: Study of ExoFlo for the Treatment of Medically Refractory Crohn's Disease |
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| Active, not recruiting | 1 | 10 | US | ExoFlo | Direct Biologics, LLC | Crohn Disease, Inflammatory Bowel Diseases | 12/24 | 12/24 | | |
NCT04657458: Expanded Access for Use of bmMSC-Derived Extracellular Vesicles in Patients With COVID-19 Associated ARDS |
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| No Longer Available | N/A | | NA | ExoFlo | Direct Biologics, LLC | Covid19, ARDS, Hypoxia, Cytokine Storm | | | | |
NCT05215288: Expanded Access for Use of ExoFlo in Abdominal Solid Organ Transplant Patients |
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| No Longer Available | N/A | 20 | US | ExoFlo | Direct Biologics, LLC | Solid Organ Transplant Rejection, Organ Rejection Transplants, Organ Rejection | | | | |
SPARES, NCT04578392: MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe |
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| Recruiting | N/A | 181 | Europe, Canada, US | high ligation of ileocolic artery, mesenteric sparing | The Cleveland Clinic | Crohn Disease | 12/23 | 12/27 | | |
| Coordinator, Research |
| Recruiting | 4 | 292 | US | Amnion-Intermediate-Chorion, AIC, Amnion-Chorion-Amnion, ACA, Standard of Care, SOC | Cellution Biologics, SerenaGroup, Inc., LifeCell | Diabetic Foot Ulcer, Venous Leg Ulcer | 12/26 | 07/27 | | |
| Recruiting | 4 | 2650 | US | Zoledronic Acid 5Mg/Bag 100Ml Inj, Reclast, Placebo | California Pacific Medical Center Research Institute, National Institute on Aging (NIA), University of California, San Francisco, Duke University, University of Pittsburgh, Parkinson's Foundation | Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia With Lewy Bodies | 10/25 | 10/25 | | |
NCT05078827: Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis |
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| Completed | 3 | 458 | US | Test Product (A): Fluorouracil Cream, 5% topical cream, Experimental, Reference Product (B): Fluorouracil 5% Topical Cream of Mylan Pharmaceuticals Inc., Morgantown, WV 26505 U.S.A., Active Comparator, Placebo Product (C): Test vehicle cream for fluorouracil 5% of Encube Ethicals Pvt. Ltd., India, Placebo Comparator | Encube Ethicals Pvt. Ltd., CBCC Global Research | Actinic Keratoses | 11/22 | 12/22 | | |
| Completed | 3 | 558 | US | ReMMi-D Digital Therapeutic | Click Therapeutics, Inc. | Migraine, Episodic Migraine, Headache, Headache, Migraine | 05/24 | 05/24 | | |
OPERA-T, NCT05238116 / 2021-004554-32: Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis ( Study) |
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| Recruiting | 3 | 123 | Europe, Canada, US, RoW | PC945, Placebo | Pulmocide Ltd | Refractory IPA | 03/26 | 04/26 | | |
NCT06004388: Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C) |
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| Completed | 3 | 110 | US | Click Digital Therapeutic | Click Therapeutics, Inc. | Migraine, Episodic Migraine, Headache, Headache, Migraine | 05/24 | 06/24 | | |
SKOAP, NCT04504812: A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain |
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| Active, not recruiting | 3 | 1800 | US | Duloxetine, Cymbalta, Intra-Articular Injection, Nerve Procedure with long acting blocks, Nerve Procedure with nerve ablation, Pain Coping Skills Training, Best Practices | Johns Hopkins University, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Knee Osteoarthritis | 03/25 | 03/25 | | |
CONVOKE, NCT05838625: Study of Two Digital Therapeutics for the Treatment of Experiential Negative Symptoms of Schizophrenia |
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| Recruiting | 3 | 432 | US | Digital Therapeutic | Click Therapeutics, Inc., Boehringer Ingelheim | Schizophrenia | 06/25 | 07/25 | | |
NCT06067984: An Extension Study of a Second Course of a Digital Therapeutic for the Treatment of Experiential Negative Symptoms of Schizophrenia |
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| Active, not recruiting | 3 | 75 | US | Study App | Click Therapeutics, Inc., Boehringer Ingelheim | Schizophrenia, Negative Symptoms in Schizophrenia | 04/25 | 05/25 | | |
| Active, not recruiting | 2/3 | 1500 | US | ABBV-CLS-7262, DNL343 | Merit E. Cudkowicz, MD, Massachusetts General Hospital | Amyotrophic Lateral Sclerosis | 07/25 | 04/26 | | |
NCT06365437: A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation |
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| Completed | 2 | 33 | Europe | TCD601, Siplizumab, Tacrolimus (TAC), Corticosteroids (CS), Mycophenolate Mofetil (MMF), ATG | ITB-Med LLC | Kidney Transplantation | 12/24 | 12/24 | | |
| Recruiting | 2 | 25 | Europe, Canada, Japan, US, RoW | nedosiran, DCR-PHXC | Dicerna Pharmaceuticals, Inc., a Novo Nordisk company | Primary Hyperoxaluria, Primary Hyperoxaluria Type 1, Primary Hyperoxaluria Type 2, Primary Hyperoxaluria Type 3 | 12/24 | 12/24 | | |
NCT03651700: Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia |
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| Completed | 2 | 86 | US | Active TMS, Sham TMS, CILT, Constraint Induced Language Therapy | H. Branch Coslett, National Institutes of Health (NIH), National Institute on Deafness and Other Communication Disorders (NIDCD) | Aphasia | 08/24 | 08/24 | | |
CHASE, NCT05727878: Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED |
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| Recruiting | 2 | 90 | US, RoW | KPI-012, KPI-012 Vehicle | Combangio, Inc, Kala Pharmaceuticals, Inc. | Persistent Corneal Epithelial Defect | 03/25 | 10/25 | | |
NCT05733546: A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder |
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| Recruiting | 2 | 102 | US | Psilocybin, COMP360 | COMPASS Pathways | Major Depressive Disorder | 10/24 | 11/24 | | |
NCT04270175: Daratumumab, Pomalidomide, and Dexamethasone (DPd) in Relapsed/Refractory Light Chain Amyloidosis Patients Previously Exposed to Daratumumab |
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| Recruiting | 2 | 21 | US | Daratumumab SC, Faspro, Pomalidomide, Dexamethasone | Weill Medical College of Cornell University, Janssen Scientific Affairs, LLC | Amyloid, AL Amyloidosis, Refractory AL Amyloidosis | 12/25 | 12/29 | | |
NCT04803058: A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PERSPECTIVE) |
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| Recruiting | 2 | 18 | US, RoW | TCD601 | ITB-Med LLC | Kidney Transplantation | 03/27 | 03/30 | | |
| Not yet recruiting | 2 | 20 | US | Sodium Thiosulfate (STS) | Robyn T. Domsic, MD, MPH, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Systemic Sclerosis (SSc), Dermatomyositis, Mixed Connective Tissue Disease (MCTD), Calcinosis | 05/25 | 11/25 | | |
| Active, not recruiting | 2 | 96 | Europe | TCD601, Placebo | ITB-Med LLC | Diabetes Mellitus, Type 1 | 01/25 | 01/25 | | |
| Not yet recruiting | 2 | 30 | Canada | AMT-143 hydrogel containing containing ropivacaine, AMT-143, Ropivacaine, Placebo | AmacaThera Inc. | Hernia, Hernia, Abdominal | 03/26 | 05/26 | | |
| Recruiting | 2 | 90 | US | TCD601, siplizumab, belatacept, ATG, antithymocyte globulin, TAC, tacrolimus, MPA, mycophenolic acid, Corticosteroids | ITB-Med LLC | Renal Transplantation | 07/25 | 10/26 | | |
NCT04311632: A Dose Escalation Study in de Novo Renal Transplantation |
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| Completed | 2 | 13 | US | TCD601, Tacrolimus (TAC), Corticosteroids (CS), Mycophenolate Mofetil (MMF), ATG | ITB-Med LLC | Kidney Transplantation | 10/23 | 10/23 | | |
NCT04464980: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD) |
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| Recruiting | 2 | 2190 | US | SL-BUP, sublingual buprenorphine, Suboxone, XR-BUP, extended-release buprenorphine, CAM2038, Brixadi, XR-NTX, extended-release naltrexone, Vivitrol, MM, MMR, MMD | NYU Langone Health, New York State Psychiatric Institute, Columbia University, Harvard Medical School (HMS and HSDM), Mclean Hospital, National Institute on Drug Abuse (NIDA), The Emmes Company, LLC | Opioid Use Disorder (OUD) | 07/26 | 12/26 | | |
NCT04803006: A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PANORAMA) |
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| Recruiting | 2 | 18 | US | TCD601 | ITB-Med LLC | Kidney Transplantation | 07/27 | 07/30 | | |
NCT04892251: Ketamine Assisted Psychotherapy for Opioid Use Disorder |
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| Recruiting | 1/2 | 60 | US | MORE+KAP, MORE | University of Utah | Opioid-use Disorder | 12/23 | 05/24 | | |
NCT04482179: Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease |
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| Completed | 1 | 23 | US | Active TMS, CILT, Constraint Induced Language Therapy, Sham TMS | University of Pennsylvania, National Institutes of Health (NIH), National Institute on Deafness and Other Communication Disorders (NIDCD) | Alzheimer Disease | 08/24 | 08/24 | | |
AURORA, NCT06453668: A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients |
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| Active, not recruiting | 1 | 48 | Europe | TCD601, siplizumab | ITB-Med LLC | ALS | 11/26 | 11/26 | | |
| Recruiting | 1 | 15 | US | PBA-0405, PB004.22.0405.aF | Pure Biologics S.A., Presage Biosciences | Head and Neck Squamous Cell Carcinoma, Soft Tissue Sarcoma Adult, Triple Negative Breast Cancer | 03/25 | 03/25 | | |
MST01-AZN-05, NCT06366451: PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, and Sabestomig in HNSCC |
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| Recruiting | 1 | 15 | US | Rilvegostomig, AZD2936, Volrustomig, MEDI5752, Sabestomig, AZD7789, Pembrolizumab, Keytruda, MK-3475 | Presage Biosciences, AstraZeneca | Head and Neck Squamous Cell Carcinoma | 12/24 | 03/25 | | |
| Recruiting | 1 | 155 | US, RoW | OP-1250, Ribociclib, KISQALI®, Alpelisib, PIQRAY®, Everolimus | Olema Pharmaceuticals, Inc., Novartis | Metastatic Breast Cancer, Advanced Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, Breast Cancer | 05/26 | 06/26 | | |
NCT06798454: Single Ascending Dose Study to Evaluate Safety Tolerability, Pharmacokinetics, and Pharmacodynamics of PVT201 in Healthy Subjects and Patients (PBC/PSC) |
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| Recruiting | 1 | 30 | RoW | PVT201, Navacim, Placebo, normal saline, 0.9% NaCl | Parvus Therapeutics, Inc., Avance Clinical Pty Ltd. | Primary Biliary Cholangitis (PBC) | 02/25 | 02/25 | | |
NCT04541108: Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies |
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| Recruiting | 1 | 15 | US | Rilvegostomig, AZD2936, Volrustomig, MEDI5752, Sabestomig, AZD7789, Pembrolizumab, Keytruda, MK-3475 | Presage Biosciences, Merck Sharp & Dohme LLC | Solid Tumor | 12/31 | 12/31 | | |
NCT06802328: Treatment Protocol: Intermediate-Size Patient Population Expanded Access |
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| Available | N/A | | US | Foralumab TZLS-401 50 µg | Tiziana Life Sciences LTD | Non-Active Secondary Progressive Multiple Sclerosis | | | | |
NCT06129084: A Study to Compare the Results of FGFR Testing by Either CtDNA Blood Testing or Standard Tumor Tissue Testing |
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| Recruiting | N/A | 260 | Canada | FGFR Testing | Bernie Eigl, Vancouver Prostate Centre, Lady Davis Institute, Bladder Cancer Canada | Metastatic Bladder Cancer, Metastatic Urothelial Carcinoma | 03/25 | 05/25 | | |
| Completed | N/A | 199 | US | Cigarette flavor type, Experimental cigarette smoking | University of Oklahoma | Smoking, Cigarette | 12/22 | 01/23 | | |
NCT03869463: Computerized Cognitive Training in Young Adults With Depression |
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| Terminated | N/A | 28 | US | Computerized Cognitive Training, Control | Queens College, The City University of New York | Depressive Symptoms | 03/23 | 03/23 | | |
NCT03495011: MRI Characterization of Mammographically Detected DCIS |
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| Active, not recruiting | N/A | 122 | US | Breast MRI, Laboratory Biomarker Analysis, Oncotype Dx | University of Washington, National Cancer Institute (NCI), National Institutes of Health (NIH) | Breast Cancer, Stage 0 | 04/23 | 04/32 | | |
| Recruiting | N/A | 35 | US | MRI, blood draw, Clinical assessments | University of Vermont, National Institute of General Medical Sciences (NIGMS) | Stroke, Acute, Gait, Hemiplegic | 05/23 | 05/23 | | |
NCT04902339: Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Persons With Chronic Pain |
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| Recruiting | N/A | 75 | US | Mindfulness-Oriented Recovery Enhancement, Neurofeedback, Supportive Psychotherapy | University of Utah | Chronic Pain Syndrome, Opioid Use | 05/23 | 08/23 | | |
NCT04088773: Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease |
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| Active, not recruiting | N/A | 232 | US | blood biomarkers, stool biomarkers, MRI imaging | Children's Hospital Medical Center, Cincinnati, The Leona M. and Harry B. Helmsley Charitable Trust | Crohn Disease | 09/23 | 09/24 | | |
NCT06136936: A Study to Evaluate the Overall Effects of Treatment With Abbreviated CT-156 in People With Schizophrenia |
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| Completed | N/A | 53 | US | CT-156-C-001 | Click Therapeutics, Inc., Boehringer Ingelheim | Schizophrenia | 01/24 | 02/24 | | |
| Recruiting | N/A | 20 | US | Prototypes of breast shield and Freedom Double Electric Breast Pump | Momtech Inc. | Healthy, Breast Pumping | 09/24 | 11/24 | | |
NCT06136923: An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer |
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| Completed | N/A | 194 | US | CT-100-D-004-A, CT-100-D-004-B | Click Therapeutics, Inc. | Multiple Sclerosis, Lung Cancer, Breast Cancer | 04/24 | 05/24 | | |
NCT05465395: Upper Cervical and Thoracic Chiropractic Adjustment |
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| Suspended | N/A | 40 | US | Upper Cervical Adjustemnt, Thoracic Adjustemnt | Life University | Stress | 11/23 | 11/23 | | |
| Completed | N/A | 314 | US | FemaSeed Localized Directional Insemination | Femasys Inc. | Infertility, Male Factor | 12/23 | 04/24 | | |
CT-100-D-003, NCT06275659: An Exploratory Study to Evaluate a Digital Intervention to Disrupt Scratching in Atopic Dermatitis and Psoriasis |
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| Active, not recruiting | N/A | 120 | US | CT-100-004-A, CT-100-004-B | Click Therapeutics, Inc. | Psoriasis, Atopic Dermatitis | 02/24 | 03/24 | | |
NCT05617300: Mindfulness-based Dementia Care Partner Program to Reduce Depressive Symptoms |
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| Completed | N/A | 130 | US | Mindfulness-Based Dementia Caregiving | HealthPartners Institute | Dementia | 12/23 | 03/24 | | |
NCT04685044: Testing a 32-channel Transmit/Receive MRI Head Array |
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| Active, not recruiting | N/A | 15 | Canada | IH 1Tx32Rx Head Array | Lawson Health Research Institute | Magnetic Resonance Imaging | 12/23 | 12/23 | | |
| Completed | N/A | 172 | US | Very low nicotine cigarettes | University of Oklahoma | Cigarette Smoking, Smoking Behaviors | 03/24 | 04/24 | | |
NCT03303248: Evaluation of Web-based Transition Education to Enhance Transition Readiness |
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| Active, not recruiting | N/A | 180 | US | Web-based Educational Intervention | University of Michigan, University of Nebraska | Congenital Heart Disease, Transition, Pediatric Congenital Heart Disease | 03/25 | 03/25 | | |
NCT05119842: APrevent-VOIS-Implant-002 - a Two-Part, Open-Label, Non-Randomized Multicenter Study |
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| Recruiting | N/A | 30 | Europe, US | APrevent® VOIS-Implant | APrevent Biotech GmbH | Paralysis, Unilateral, Vocal Cord | 09/25 | 09/26 | | |
| Completed | N/A | 60 | US | alcohol beverage, Placebo beverage | University of Texas at Austin | Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder | 03/24 | 03/24 | | |
NCT04625959: Optimizing Mindfulness and Acceptance Based Behavioral Treatment for Bulimia Nervosa and Binge Eating Disorder |
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| Active, not recruiting | N/A | 256 | US | Behavioral Therapy for Eating Disorders, MABT: Mindful Awareness, MABT: Values, MABT: Emotion Modulation, MABT: Distress Tolerance | Drexel University, National Institute of Mental Health (NIMH) | Bulimia Nervosa, Bulimia; Atypical, Binge-Eating Disorder, Binge-Eating and Purging Type Anorexia Nervosa, Binge Eating | 04/24 | 04/24 | | |
NCT06330246: O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease |
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| Recruiting | N/A | 40 | US | Low oxalate fixed diets pre-colonization, Moderately high oxalate fixed diets pre-colonization, Colonization with Oxalobacter formigenes, Low oxalate fixed diets post-colonization, Moderately high oxalate fixed diets post-colonization | University of Alabama at Birmingham, University of Texas Southwestern Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Oxaluria | 12/30 | 12/31 | | |
NCT06331546: Gut Oxalate Absorption in Calcium Oxalate Stone Disease |
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| Recruiting | N/A | 80 | US | Low-oxalate diet, High-oxalate diet, soluble oxalate gut absorption test | University of Alabama at Birmingham, University of Texas Southwestern Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Oxaluria, Healthy | 12/30 | 12/31 | | |
SWAT, NCT06588101: Clinical Trial Recruitment and Retention Strategies for Family Members in the ICU |
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| Recruiting | N/A | 160 | Canada | Written informed consent with infographic, Compensation | Lady Davis Institute, Canadian Institutes of Health Research (CIHR) | Family Members, Recruitment, Clinical Study, Retention, Recruitment of Participants, Study Enrollment, Retention of Participants, Compensation Incentives | 04/25 | 12/25 | | |
NCT06431386: Behavioural Activation Therapy and Esketamine for Resistant Depression |
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| Recruiting | N/A | 40 | Canada | Behavioural Activation (BA) Therapy, Esketamine | The Royal's Institute of Mental Health Research | Depressive Disorder, Treatment-Resistant, Depressive Disorder, Major, Bipolar Disorder | 08/26 | 08/26 | | |
| Completed | N/A | 68 | US | Alcohol beverage, Placebo beverage | University of Texas at Austin | Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder | 06/24 | 06/24 | | |
NCT04279483: GeoScan and Remote Geo Smoking Study: Neural and Behavioral Correlates of Smokers' Exposure to Retail Environments |
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| Completed | N/A | 336 | US | 7-11, CVS | Abramson Cancer Center at Penn Medicine, National Cancer Institute (NCI), New York University, Stanford University | Smoking, Tobacco, Smoking, Smoking, Cigarette | 06/24 | 06/24 | | |
NCT05884437: The Effects of Chiropractic in Adults With Metabolic Syndrome |
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| Suspended | N/A | 10 | US | Chiropractic adjustment | Life University | Metabolic Syndrome | 07/25 | 12/25 | | |
I-YMSC, NCT06657950: Treatments for Improving Mood in Women Survivors of Interpersonal Violence: A Community-Engaged Study-1.2 |
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| Recruiting | N/A | 15 | US | Integrative hatha yoga and mindful self-compassion | Butler Hospital, National Center for Complementary and Integrative Health (NCCIH) | Distress | 09/25 | 09/25 | | |
NCT06385392: Continuous Wearable Monitor for the Detection and Release of Freezing of Gait. |
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| Recruiting | N/A | 36 | US | Haptic module and insole device | HealthPartners Institute | Parkinson Disease | 05/25 | 05/25 | | |
NCT06172660: Real-World Effectiveness of Perinatal RSV Immunoprophylaxis |
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| Recruiting | N/A | 3750 | US | Nirsevimab, RSV vaccines | Yale University, National Institute of Allergy and Infectious Diseases (NIAID) | RSV Infection | 12/28 | 12/28 | | |
| Recruiting | N/A | 750 | Canada | Cardiac monitoring device | Population Health Research Institute | Atrial Fibrillation, Atrial Flutter | 08/26 | 12/26 | | |
| Recruiting | N/A | 62 | US | Morning Exercise | Rutgers, The State University of New Jersey | Sleep, Mood, Stress | 12/26 | 12/26 | | |
Lublin, NCT06217081: 3M™ Topical Tissue Adhesive Versus Commercially Available Tissue Adhesive for the Closure of Lacerations and Incisions |
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| Recruiting | N/A | 452 | US | 3M Topical Tissue Adhesive, Histoacryl® Blue Topical Skin Adhesive | Solventum US LLC, United States Department of Defense, The University of Texas Health Science Center at San Antonio, 3M | Trauma-related Wound, Surgical Incision, Surgical Wound, Laceration | 11/25 | 12/25 | | |
NCT03556683: Phase I Assessment of Hypertonic Saline in Moderate to Severe Asthmatics |
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| Completed | N/A | 22 | US | 3% Hypertonic Saline, 7% Hypertonic Saline | University of North Carolina, Chapel Hill, National Heart, Lung, and Blood Institute (NHLBI) | Moderate to Severe Asthma | 06/24 | 06/24 | | |
| Recruiting | N/A | 581 | US | | CoMind Technologies Limited, Lindus Health | Intracranial Pressure, Intracranial Pressure Changes, Traumatic Brain Injury, Intracerebral Hemorrhage, Encephalitis, Encephalopathy, Hydrocephalus, Stroke, Autoregulation | 10/25 | 10/25 | | |
| Recruiting | N/A | 50 | US | Pulmonary Valve Replacement Surgery | Autus Valve Technologies, Inc. | Congenital Heart Disease | 08/26 | 02/36 | | |
| Enrolling by invitation | N/A | 1642 | US | Biopsy strategy | University of Pennsylvania, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis | 12/28 | 06/29 | | |
| Recruiting | N/A | 800 | US | Myriad Matrix™ and Myriad Morcells™ | Aroa Biosurgery Limited | Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus, Anal Fistula, Hidradenitis Suppurativa, Pressure Injury | 01/28 | 01/29 | | |
NCT06770998: A Study of a Novel EEG Neurofeedback System for PTSD Treatment |
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| Not yet recruiting | N/A | 250 | US | EEG-neurofeedback training, Prism training, amyg-EFP training, active Prism training, Sham training, sham Prism training | Foundation for Atlanta Veterans Education and Research, Inc., GrayMatters Health Ltd., Rochester Institute of Technology, New York University Grossman School of Medicine, Atlanta VA Medical Center, Birmingham VA Health Care System, Ralph H. Johnson VA Medical Center, VA Boston Healthcare System, CTP Inc, BioStats Statistical Consulting Ltd, ShareCRF, United States Department of Defense | Stress Disorders, Post-Traumatic | 06/27 | 08/27 | | |
| Recruiting | N/A | 900 | Canada | A-EAAA Sexual Assault Resistance Education Program immediately, Girls -- Flip the Script with EAAA, Usual care + A-EAAA at 6 months | University of Windsor, Public Health Agency of Canada (PHAC) | Sexual Assault | 12/25 | 12/25 | | |
| Not yet recruiting | N/A | 1137 | US | Self-Management, Community-Based | Stanford University | Obesity and Overweight, Nutrition, Chronic Disease, Diabetes, Pregnancy | 07/29 | 03/30 | | |
| Not yet recruiting | N/A | 100 | US | Surveys and Interviews - Arm A, COPD Care Pathway | Wake Forest University Health Sciences, National Cancer Institute (NCI) | Chronic Obstructive Pulmonary Disease, Lung Cancer, Head and Neck Cancer | 08/25 | 08/25 | | |
NCT05893927: Impact of a Diabetes Education Mobile Web Application on Patients With Uncontrolled Type 2 Diabetes |
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| Recruiting | N/A | 120 | US | Diabetes education web site application | The Reading Hospital and Medical Center, Reading Hospital Foundation, Complete Statistical Services (Consult-Stat) | Diabetes Mellitus, Type 2, Diabetes Education, Lifestyle Modification | 09/25 | 09/25 | | |
| Active, not recruiting | N/A | 100 | US | Checkpoint BEST System, Brief Electrical Stimulation (BES) Therapy | Checkpoint Surgical Inc., Congressionally Directed Medical Research Programs | Cubital Tunnel Syndrome, Nerve Compression, Nerve Injury, Ulnar Neuropathies | 12/25 | 12/25 | | |
NCT05473013: Optimizing Digital Health Technology Interventions to Increase Skill Acquisition and Utilization |
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| Recruiting | N/A | 264 | US | Behavioral Therapy for Eating Disorders, Skills Monitoring On, Enhanced Skills Monitoring, Automated Reminder Messages, Micro-Intervention 1, JITAIs, Micro-Intervention 2 | Drexel University, National Institute of Mental Health (NIMH) | Bulimia Nervosa, Bulimia, Binge Eating, Binge-Eating Disorder | 12/25 | 03/26 | | |
| Recruiting | N/A | 573 | US | FemBloc | Femasys Inc. | Contraception | 12/29 | 06/31 | | |
