Zhang, Wei |
NCT04504864: Low-dose Aspirin Therapy in Patients With Ischemic Stroke and Microbleeds |
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| Recruiting | 4 | 400 | RoW | low-dose aspirin, conventional-does aspirin | Xijing Hospital, Shaanxi Provincial People's Hospital, The First Affiliated Hospital of Jiaotong University, Tang-Du Hospital, The First Affiliated Hospital of Xi'an Medical University, Xi'an Central Hospital, Xiangyang Central Hospital, Baoji Central Hospital | Ischemic Stroke | 02/22 | 08/22 | | |
| Active, not recruiting | 4 | 130 | RoW | Dexamethasone lipid microsphere plus ropivacaine, ropivacaine plus D-PAL, Ropivacaine alone | Beijing Tiantan Hospital | Pain, Postoperative | 09/23 | 12/23 | | |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
NCT05908695: An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease |
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| Recruiting | 4 | 1312 | RoW | GV-971, Placebo | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | Alzheimer's Disease | 06/29 | 12/29 | | |
NCT04504396: Safety and Efficacy of PB-119 in Subjects With Type 2 Diabetes and Not Well-controlled by Metformin Monotherapy |
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| Completed | 3 | 620 | RoW | GLP-1 receptor agonist, Placebo, PB-119 Placebo | PegBio Co., Ltd. | Type 2 Diabetes Mellitus (T2DM) | 09/22 | 05/23 | | |
NCT04683406: A Study of ZSP1273 Tablets in Patients With Acute Uncomplicated Influenza A |
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| Completed | 3 | 750 | RoW | ZSP1273 600 mg, Placebo to Oseltamivir, Oseltamivir(oral), Placebo to ZSP1273 | Guangdong Raynovent Biotech Co., Ltd | Influenza A | 04/23 | 05/23 | | |
NCT06103825: A Twelve-week, Double-blind, Placebo-controlled, Randomized, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Solriamfetol in the Treatment of Excessive Daytime Sleepiness (EDS) in Patients With Obstructive Sleep Apnea (OSA) |
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| Recruiting | 3 | 204 | RoW | Solriamfetol, Placebo | Ignis Therapeutics (Suzhou) Limited | Excessive Daytime Sleepiness Associated With Obstructive Sleep Apnea | 09/24 | 10/24 | | |
| Recruiting | 3 | 1200 | Europe, Canada, Japan, US, RoW | Remternetug, LY3372993, Placebo | Eli Lilly and Company | Alzheimer's Disease | 04/29 | 10/30 | | |
| Recruiting | 3 | 1500 | Europe, RoW | Donanemab, (LY3002813), Placebo | Eli Lilly and Company | Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders | 04/27 | 04/27 | | |
NCT05215379: Neoadjuvant Chemoradiation Therapy Combined With Immunotherapy for MSS Ultra-low Rectal Cancer |
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| Recruiting | 2/3 | 180 | RoW | xintilimab injection, Control | Changhai Hospital | Neoadjuvant Chemoradiation Therapy, Rectal Cancer, Immunotherapy, Microsatellite Instability Low | 10/24 | 04/25 | | |
NCT05811442: Study of 50561 in Patients With Mild or Moderate Alzheimer's Disease |
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| Recruiting | 2a | 60 | RoW | 50561 high dose, 50561 low dose, Placebo | Beijing Joekai Biotechnology LLC | Alzheimer's Disease | 05/24 | 06/24 | | |
NCT03746223: Intravitreal Methotrexate and R2(Rituximab & Lenalidomide) Regimen in Newly-diagnosed Primary Vitreoretinal Lymphoma |
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| Recruiting | 2 | 42 | RoW | Methotrexate, Rituximab, Lenalidomide | Peking Union Medical College Hospital | Primary Intraocular Lymphoma | 11/20 | 10/25 | | |
NCT05229029: RSYR for Fatigue Reduction in Cancer Fatigue Caused by Chemotherapy |
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| Active, not recruiting | 2 | 196 | RoW | TCM Formula, RSYR decoction, Placebo, Placebo dicoction | Peking University Cancer Hospital & Institute | Cancer-related Problem/Condition | 09/23 | 06/24 | | |
NCT04899427: Phase II Study of Orelabrutinib Combined With PD-1 Inhibitor in Relapsed/Refractory Primary Central Nervous System Lymphoma |
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| Recruiting | 2 | 32 | RoW | orelabrutinib, Sintilimab, Tislelizumab | Peking Union Medical College Hospital, Beijing Hospital, Beijing Tongren Hospital, Beijing Luhe Hospital, Shanxi Province Renmin Hospital, Henan Cancer Hospital, Henan Province Renmin Hospital, The Second Affiliated Hospital of Dalian Medical University, The Forth Hospital of Hebei Medical University, The First Hospital of Chinese Medical University, Qilu Hospital of Shandong University, The First Hospital of Zhengzhou University | Primary Central Nervous System Lymphoma | 03/23 | 10/23 | | |
NCT06259526: A Study of the Effectiveness and Safety of JS1-1-01 in Patients With Moderate to Severe Depression |
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| Recruiting | 2 | 260 | RoW | Placebo group, JS1-1-01 placebo pills; Duloxetine hydrochloride placebo capsules, JS1-1-01 low-dose group, JS1-1-01 pills; JS1-1-01 placebo pills; Duloxetine hydrochloride placebo capsules, JS1-1-01 pills; JS1-1-01 placebo pills, JS1-1-01 high-dose group, JS1-1-01 pills; Duloxetine hydrochloride placebo capsules, Active drug group, JS1-1-01 placebo pills; Duloxetine hydrochloride enteric coated capsule | Tasly Pharmaceutical Group Co., Ltd | Depression | 04/25 | 04/25 | | |
NCT05179213: Azacytidine Plus Chidamide in the Treatment of Relapsed and Refractory Angioimmunoblastic T-cell Lymphoma |
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| Not yet recruiting | 2 | 20 | RoW | Azacitidine, Chidamide | Peking Union Medical College Hospital, Beijing Longfu Hospital | Angioimmunoblastic T-cell Lymphoma | 01/24 | 05/24 | | |
NCT06093841: Relmacabtagene Autoleucel As Second-Line Therapy in Adult Patients with Aggressive B-cell NHL |
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| Active, not recruiting | 2 | 46 | RoW | Relmacabtagene Autoleucel, JWCAR029, Fludarabine, Cyclophosphamide | Shanghai Ming Ju Biotechnology Co., Ltd. | Lymphoma, Large B-Cell, Diffuse, Follicular Lymphoma Grade 3B, High-grade B-cell Lymphoma, Mediastinal B-Cell Diffuse Large Cell Lymphoma | 01/24 | 11/29 | | |
NCT05555901: The Efficacy and Safety of Fruquintinib Plus Chemotherapy as Second-line Treatment in Metastatic Colorectal Cancer |
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| Recruiting | 2 | 116 | RoW | Fruquintinib+ chemotherapy, Bevacizumab+ chemotherapy | Fudan University | Metastatic Colorectal Cancer | 09/25 | 09/25 | | |
NCT02987244: Chidamide Plus CHOEP Combined With Upfront ASCT in Untreated Peripheral T-cell Lymphoma |
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| Recruiting | 1/2 | 100 | RoW | Chidamide, epidaza, Cyclophosphamide, Epirubicin, Vindesine, Etoposide, Prednisone | Peking Union Medical College Hospital, Chinese PLA General Hospital, Peking University First Hospital, Peking University Third Hospital, Peking University Cancer Hospital & Institute, Tianjin Medical University Cancer Institute and Hospital | T Cell Non-Hodgkin's Lymphoma | 03/20 | 03/23 | | |
GLORY, NCT04270591: Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer |
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| Recruiting | 1/2 | 183 | Japan, US, RoW | Glumetinib, SCC244 | Haihe Biopharma Co., Ltd. | C-Met Exon 14 Mutation | 10/23 | 12/23 | | |
NCT05464433: Tislelizumab Combined With Mitoxantrone Hydrochloride Liposome in Extranodal Natural Killer/T Cell Lymphoma |
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| Recruiting | 1/2 | 46 | RoW | Tislelizumab combined with Liposomal mitoxantrone hydrochloride, Maintenance of tislelizumab | Sun Yat-sen University | Extranodal Natural Killer T Cell Lymphoma | 01/24 | 01/25 | | |
| Recruiting | 1/2 | 120 | RoW | Chidamide, HDACi, Fludarabine and cyclophosphamide, FC regimen, Anti-CD19 CAR-T cells, Relma-cel, Axi-cel, Other commercial CAR-T cells, Experimental CAR-T cells | Chinese PLA General Hospital | Non Hodgkin's Lymphoma | 06/24 | 06/25 | | |
NCT06393413: To Explore the Therapeutic Potential of Jiedu Yizhi Formula for Alzheimer 's Disease |
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| Completed | 1 | 62 | RoW | Jiedu Yizhi Formula, Donepezil Hydrochloride Tablets | Changchun University of Chinese Medicine | Ensure the Legality and Compliance of the Testing Process | 12/23 | 04/24 | | |
NCT05240950: Anti-CEA CAR-T Cells to Treat Colorectal Liver Metastases |
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| Recruiting | 1 | 18 | RoW | Anti-CEA CAR-T Cells | Changhai Hospital | Colorectal Cancer, Metastatic Liver Cancer | 12/23 | 12/26 | | |
NCT05577091: Tris-CAR-T Cell Therapy for Recurrent Glioblastoma |
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| Recruiting | 1 | 10 | RoW | Inverse correlated dual-target, truncated IL7Ra modified CAR -expressing autologous T-lymphocytes., Autologous Tris-CAR-T cell. | Beijing Tiantan Hospital, Beijing Neurosurgical Institute, Tasly Pharmaceutical Group Co., Ltd | Recurrent Glioblastoma | 11/24 | 11/32 | | |
NCT06515938: Study on New Strategies for Hepatitis B Virus Immunization |
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| Completed | N/A | 1169 | RoW | 20μg Engerix-B hepatitis B vaccine, 20μg Kangtai hepatitis B vaccine, 60μg Kangtai hepatitis B vaccine, 20μg CHO | Wu Jiang | Vaccine Reaction | 06/14 | 12/15 | | |
NCT05159804: Association Between Carotid Plaque Length and Cardiovascular Events |
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| Active, not recruiting | N/A | 3637 | RoW | | Changhai Hospital, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 904 Hospital of the PLA Joint Logistics Support Force, Gongli Hospital, Yueyang Hospital, Shanghai University of Traditional Chinese medicine | Coronary Arteriosclerosis | 06/21 | 12/30 | | |
| Recruiting | N/A | 630 | Europe, US, RoW | ROX index algorithm | Hospital Universitari Vall d'Hebron Research Institute | Acute Hypoxemic Respiratory Failure | 12/24 | 06/25 | | |
NCT05843487: Association Between Carotid Plaque Length and Cardiovascular Outcomes |
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| Active, not recruiting | N/A | 3000 | RoW | | Changhai Hospital, Yueyang Hospital, Shanghai University of Traditional Chinese medicine, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 904 Hospital of the PLA Joint Logistics Support Force, Gongli Hospital | Coronary Artery Disease, Carotid Plaque | 03/22 | 12/30 | | |
NCT03958435: Real-world Retrospective Data Analysis of Adjuvant Therapy for Patients With Stage II-III Colon Cancer After Radical Surgery |
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| Recruiting | N/A | 20000 | RoW | | Second Affiliated Hospital, School of Medicine, Zhejiang University | Stage II Colon Cancer, Stage III Colon Cancer, Adjuvant Therapy | 10/22 | 12/23 | | |
| Recruiting | N/A | 10254 | RoW | | Limeng Chen | Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder | 12/24 | 12/24 | | |
NCT05485857: Influence of Arrangement of Small Intestine Order on the Recovery of Bowel Function After Laparoscopic Colorectal Surgery |
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| Completed | N/A | 160 | RoW | Arrangement of small intestine order before close the abdomen | Changhai Hospital | Postoperative Complications | 02/23 | 03/23 | | |
NCT05634473: A Study to Evaluate the Sensitivity and Specificity of Inhaled Methacholine in Bronchial Provocation Test |
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| Not yet recruiting | N/A | 280 | RoW | Methacholine Chloride | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Asthma | 02/23 | 06/23 | | |
NCT04853238: Chronic Obstructive Pulmonary Disease (COPD) Maintenance Treatment Patterns in China |
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| Completed | N/A | 1507 | RoW | Prospective observational cohort study | GlaxoSmithKline | Pulmonary Disease, Chronic Obstructive | 11/22 | 02/23 | | |
ZCFZZLXGBDFYHZ, NCT05692258: Acupuncture as an Adjunctive Therapy for Covid-19 Omicron Randomised Controlled Trial in Patients With Moderate/Severe Pneumonia |
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| Recruiting | N/A | 146 | RoW | Acupuncture, basic therapy | The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine | Acupuncture, Covid-19 Omicron, Pulmonary Function | 04/23 | 04/23 | | |
NCT05752097: [18F]AlF-NOTA-FAPI-04 PET/CT in Inflammation and Fibrosis in Renal Diseases |
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| Recruiting | N/A | 30 | RoW | [18F]AlF-NOTA-FAPI-04 PET/CT examination, Renal puncture biopsy | Sichuan Provincial People's Hospital | 18F-FAPI PET/CT Examination, Renal Puncture Biopsy | 08/24 | 11/24 | | |
GJZLBQGNZA, NCT05749354: Clinical Efficacy of Acupuncture on the Liver Meridian in Men With Erectile Dysfunction Reserve |
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| Recruiting | N/A | 159 | RoW | electroacupuncture, acupuncture | The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine | Erectile Dysfunction, Acupuncture Therapy, Median Nerve Disease | 12/23 | 12/23 | | |
PCOS, NCT04984070: Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety |
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| Recruiting | N/A | 100 | RoW | Oral Contraceptives, Combined, Danie-35, Drospirenone and Ethinylestradiol Tablets (I), Drospirenone and Ethinylestradiol Tablets (Ⅱ), Metformin Pill, Metformin, lifestyle intervention | Fudan University | PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety | 12/23 | 12/24 | | |
NCT05183425: Patient-derived Organoids Predicts the Clinical Efficiency of Colorectal Liver Metastasis |
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| Recruiting | N/A | 60 | RoW | | Changhai Hospital | Explore the Consistency of Drug Sensitivity Between Primary Colorectal Cancer and Liver Metastases | 12/23 | 12/24 | | |
| Recruiting | N/A | 198 | RoW | electropuncture, acupuncture | The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine | Ovarian Reserve, Acupuncture Therapy, Meridian | 12/23 | 12/23 | | |
NCT05815069: [18F]AlF-NOTA-pentixather PET/CT in Patients With Suspected Primary Hyperaldosteronism |
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| Recruiting | N/A | 20 | RoW | [18F]AlF-NOTA-pentixather PET/CT, pathological examination | Sichuan Provincial People's Hospital | Aldosterone-Producing Adenoma | 01/24 | 06/24 | | |
| Recruiting | N/A | 20 | RoW | Glofitamab | Peking Union Medical College Hospital | DLBCL - Diffuse Large B Cell Lymphoma | 12/27 | 12/28 | | |
NCT06254716: A Study on the Prognosis of Two Different Surgery Methods in Patients With Rectal Endometriosis |
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| Recruiting | N/A | 90 | RoW | disc resection, segmental resection | Fudan University | Gastrointestinal Function, Quality of Life, Pregnancy Outcomes | 12/24 | 12/24 | | |
proOMCRC, NCT04716257: A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients |
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| Recruiting | N/A | 400 | RoW | | West China Hospital, Sun Yat-sen University, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Changhai Hospital, Naval Medical University | Ovarian Metastasis, Colorectal Cancer | 09/25 | 09/25 | | |
NCT06204497: The Safety and Efficiency of Stent-based Diverting Technique Versus Ileostomy in Rectal Cancer Patients |
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| Recruiting | N/A | 570 | RoW | Stent-based Diverting Technique | Sir Run Run Shaw Hospital | Rectal Neoplasms | 12/24 | 06/25 | | |
VERONICA, NCT05486923: Validity and Reliability Evaluation of the PRO-CTCAE for Adult-type Diffuse Gliomas Patients in Chinese Population |
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| Recruiting | N/A | 450 | RoW | | Huashan Hospital | Glioma, Patient Reported Outcome Measures, Self Report, Adverse Effects | 04/25 | 12/25 | | |
NCT05882552: Tilted Gaze Target Test in the Examination of Children With Superior Oblique Muscle Palsy |
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| Not yet recruiting | N/A | 80 | NA | Tilted Gaze Target Tast, Conventional Examination Methods | Tianjin Eye Hospital | Children With Torticollis | 06/24 | 12/24 | | |
NCT06510127: An AI Model Predicts the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer: a Multicenter, Bidirectional Cohort Study |
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| Enrolling by invitation | N/A | 840 | RoW | | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Jinan University | Breast Cancer | 06/25 | 01/26 | | |
NCT03651986: Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules |
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| Active, not recruiting | N/A | 10560 | RoW | ctDNA methylation analysis by NGS | AnchorDx Medical Co., Ltd., Xiangya Hospital of Central South University, West China Hospital, Shanghai Zhongshan Hospital, Shanghai Pulmonary Hospital affiliated to Tongji University, First Hospital of China Medical University, Guizhou Provincial People's Hospital, Shanghai Chest Hospital, First Affiliated Hospital, Sun Yat-Sen University, First Affiliated Hospital Xi'an Jiaotong University, Qilu Hospital of Shandong University, Inner Mongolia People's Hospital, The First Affiliated Hospital with Nanjing Medical University, The First Affiliated Hospital of Zhengzhou University, Second Hospital of Jilin University, LanZhou University, Peking University Third Hospital, The First People's Hospital of Yunnan, Shantou Affiliated Hospital of Sun Yat-Sen University, Ruijin Hospital, The Shanghai Jiao Tong University Medical School, Tongji Hospital, The First Affiliated Hospital of Guangzhou Medical University, Xijing Hospital, Air Force Medical University of PLA, Shenzhen People's Hospital, Henan Provincial People's Hospital, Beijing Chao Yang Hospital, Xiamen Second Hospital, The First Affiliated Hospital of Nanchang University | Pulmonary Nodules | 09/24 | 06/25 | | |
NCT05514327: A Study of Ultra-fraction Radiotherapy Bridging CART in R/R DLBCL |
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| Recruiting | N/A | 20 | RoW | ultra-fraction radiotherapy | Peking Union Medical College Hospital | Diffuse Large B Cell Lymphoma, CAR-T, Radiotherapy, Bridging Therapy | 09/24 | 12/24 | | |
NCT06606509: The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM). |
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| Not yet recruiting | N/A | 1000 | RoW | Continuous Glucose Monitoring System (GX-01S) | Nanjing First Hospital, Nanjing Medical University | Type1 Diabetes Mellitus | 10/26 | 06/27 | | |
NCT04837222: A Study of Brentuximab Vedotin in Adults With CD30-positive Lymphoma |
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| Active, not recruiting | N/A | 1000 | RoW | No Intervention | Takeda | Lymphoma | 06/26 | 06/26 | | |
NCT06723366: Protective Effect of Angong Niuhuang Against Negative Inflammatory Response and Neurologic Dysfunction After Cardiovascular Surgery |
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| Not yet recruiting | N/A | 120 | RoW | Angong Niuhuang Pill (ANP), Control (Standard treatment) | Nanjing Medical University, The First Affiliated Hospital with Nanjing Medical University, Beijing Anzhen Hospital, Capital Medicine University | Cardio-pulmonary Bypass, Cardiovascular Surgery, Cerebral Protection, Brain Injury | 12/25 | 12/25 | | |
| Not yet recruiting | N/A | 524 | RoW | Laparoscopic radical hysterectomy incorporating modified tumor-free techniques, Abdominal radical hysterectomy | Peking Union Medical College Hospital, Hebei Medical University Fourth Hospital, Second Hospital of Jilin University, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Cangzhou Central Hospital, Zhejiang Cancer Hospital, Hunan Provincial Maternal and Child Health Care Hospital, LanZhou University, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, The Fourth Military Medical University, Xijing Hospital, Affiliated Hospital of Shanxi University of Traditional Chinese Medicine | Cervical Cancer Stage IB2 | 07/32 | 07/32 | | |
NCT05818267: Efficacy and Safety of Regorafenib Maintenance Therapy in Patients With Metastatic Colorectal Cancer (mCRC) |
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| Recruiting | N/A | 30 | RoW | Regorafenib | Wei Zhang | Colorectal Cancer | 03/25 | 11/25 | | |
NCT05282095: Effect of HPV Integration on Prognosis of Young Women With CIN2 in China |
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| Recruiting | N/A | 300 | RoW | Follow up | Fujian Maternity and Child Health Hospital | Cervical Intraepithelial Neoplasia, HPV Infection, Virus Integration, HSIL, High Grade Squamous Intraepithelial Lesions | 12/25 | 05/26 | | |
AIM, NCT05032053: Antithrombotic Drug Use in Patients With Ischemic Stroke and Microbleeds |
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| Recruiting | N/A | 3000 | RoW | Antithrombotic drugs | Xijing Hospital, Ankang Central Hospital, Yan'an University Affiliated Hospital | Ischemic Stroke | 12/25 | 10/26 | | |
LPS-IHH, NCT05569577: An Open Labeled RCT on the Effect of Additional hCG Injection for LPS on Pregnancy Outcomes in IHH Patients |
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| Recruiting | N/A | 46 | RoW | Additional hCG injection, estrogen and dydrogesterone | Fudan University | Luteal Phase Deficiency, Luteal Phase Support, Idiopathic Hypogonadotropic Hypogonadism | 12/25 | 12/25 | | |
NCT05923255: LISH Trial for the Hepatic Flexure and Proximal Transverse Colon Cancer |
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| Recruiting | N/A | 568 | RoW | LISH (Laparoscopic Ileocecal-Sparing Right Hemicolectomy), TRH(Traditional Laparoscopic Right Hemicolectomy) | Zhejiang University | Hepatic Flexure Colon Cancer, Proximal Transverse Colon Cancer | 05/26 | 05/31 | | |
| Recruiting | N/A | 100000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Hunan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, Wuhan University Zhongnan Hospital, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Mild Cognitive Impairment(MCI), Alzheimer Disease, Late Onset, Familial Alzheimer Disease (FAD), Vascular Dementia (VaD), Normal Control, Non-Alzheimer Degenerative Dementia | 01/38 | 01/38 | | |
| Recruiting | N/A | 40000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Henan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, Wuhan University Zhongnan Hospital, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Alzheimer Disease, Familial Alzheimer Disease (FAD) | 01/38 | 01/38 | | |
NCT05409209: Carotid Plaque Length to Predict Cardiovascular Events |
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| Active, not recruiting | N/A | 3000 | RoW | | Changhai Hospital, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 904 Hospital of the PLA Joint Logistics Support Force, Gongli Hospital, Yueyang Hospital, Shanghai University of Traditional Chinese medicine | Coronary Artery Disease | 12/21 | 12/30 | | |
NCT05513664: Real-World Effectiveness of Osimertinib for Patients With Non-Small Cell Lung Cancer |
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| Not yet recruiting | N/A | 80 | RoW | Osimertinib | Shanghai JMT-Bio Inc., CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | Locally Advanced or Metastatic Non-Small Cell Lung Cancer, EGFR Exon20 Insertion Mutations | 06/23 | 08/23 | | |
Li, Yan |
NCT04035824: Gastrodia and Uncaria Recipe in Treating Stage-one Hypertension: an Evidence-based Optimization Study |
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| Completed | 4 | 605 | RoW | Gastrodia and Uncaria granule, Placebo of Gastrodia and Uncaria granule | Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | Hypertension | 04/24 | 04/24 | | |
NCT05089448: Morning Versus Bedtime Dosing of Antihypertensive Medication |
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| Recruiting | 4 | 300 | RoW | Alisartan, Amlodipine besylate | Yan Li | Hypertension, Blood Pressure, Drug Use | 06/26 | 09/26 | | |
NCT03825692: International Clinical Study of Zhizhu Kuanzhong Capsule |
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| Recruiting | 4 | 480 | RoW | Zhizhu Kuanzhong Capsule, ZZKZ capsule, Zhizhu Kuanzhong Placebo Capsule, placebo | Xiyuan Hospital of China Academy of Chinese Medical Sciences | Functional Dyspepsia, Postprandial Distress Syndrome | 12/23 | 12/23 | | |
| Completed | 3 | 1177 | Europe, Canada, Japan, US, RoW | Mirikizumab SC, LY3074828, Mirikizumab IV, Placebo SC | Eli Lilly and Company | Ulcerative Colitis | 11/21 | 12/24 | | |
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NCT04078568: Efficacy of Immunoglobulin Plus Prednisolone in Reducing Coronary Artery Lesion in Patients With Kawasaki Disease |
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| Active, not recruiting | 3 | 3208 | RoW | IVIG, Intravenous Immunoglobulins, Human, Aspirin, Acetylsalicylic acid, Prednisolone, STEROLONE | Children's Hospital of Fudan University, Jiangxi Province Children's Hospital, First People's Hospital of Hangzhou, Shengjing Hospital, The First Hospital of Jilin University, Chengdu Women's and Children's Central Hospital, Children's Hospital of Chongqing Medical University, Inner Mongolia People's Hospital, Sichuan Provincial People's Hospital, Wuhan Union Hospital, China, Third Affiliated Hospital of Zhengzhou University, Children's Hospital of Soochow University, Yuying Children's Hospital of Wenzhou Medical University, Beijing Children's Hospital, Qilu Hospital of Shandong University | Kawasaki Disease | 12/24 | 12/25 | | |
| Active, not recruiting | 3 | 404 | Europe, Canada, Japan, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo | Chinook Therapeutics, Inc. | IgA Nephropathy, Immunoglobulin A Nephropathy | 12/26 | 12/26 | | |
NCT05433480: A Study of BPI-16350 in Combination With Fulvestrant in Patients With HR+ and HER2- Locally Advanced, Recurrent or Metastatic Breast Cancer |
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| Active, not recruiting | 3 | 274 | RoW | BPI-16350, placebo, Fulvestrant | Betta Pharmaceuticals Co., Ltd. | Breast Cancer | 12/23 | 07/25 | | |
nAMD, NCT05461339: TAB014 Compared to Lucentis® in Patients with Neovascular Age-related Macular Degeneration |
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| Active, not recruiting | 3 | 488 | RoW | TAB014 Monoclonal Antibody Injection, TAB014, Ranibizumab Injection [Lucentis], Lucentis | TOT Biopharm Co., Ltd., Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | Neovascular Age-related Macular Degeneration | 09/24 | 02/25 | | |
NCT06292013: A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a) |
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| Recruiting | 3 | 12500 | Europe, Canada, Japan, US, RoW | Lepodisiran Sodium, LY3819469, Placebo | Eli Lilly and Company | Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a) | 03/29 | 03/29 | | |
QWINT-2, NCT05362058: A Study of Insulin Efsitora Alfa (LY3209590) Compared to Degludec in Adults With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time |
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| Completed | 3 | 928 | Europe, Canada, Japan, US, RoW | Insulin Efsitora Alfa, LY3209590 and Basal Insulin-FC, Insulin Degludec | Eli Lilly and Company | Diabetes, Type 2 Diabetes | 04/24 | 04/24 | | |
TRAPP, NCT05811676: Tranexamic Acid for the Prevention of Postpartum Hemorrhage in Pregnant Women with Placenta Previa |
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| Recruiting | 3 | 1680 | RoW | Tranexamic acid, 0.9% sodium chloride | Guangzhou Medical University, Dongguan Maternal and Child Health Care Hospital, Foshan Women and Children Hospital, BoAi Hospital of Zhongshan, Women and Children's Hospital of Chongqing Medical University, Tianjin Central Hospital of Gynecology Obstetrics, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, Urumqi Maternal and Child Health Care Hospital, Zhuhai Women and Children's Hospital, The First Affiliated Hospital of Zhengzhou University, Hunan Provincial Maternal and Child Health Care Hospital, Dalian women and children's medical group, Nanfang Hospital, Southern Medical University, Huadu District People's Hospital of Guangzhou, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, First Affiliated Hospital, Sun Yat-Sen University, Shenzhen Maternity & Child Healthcare Hospital, Shenzhen Baoan Women's and Children's Hospital, Dongguan People's Hospital, First Affiliated Hospital of Xinjiang Medical University, Tongji Hospital, Peking Union Medical College, Peking University First Hospital, The First Affiliated Hospital of Guangzhou Medical University, Second Affiliated Hospital of Guangzhou Medical University, Fifth Affiliated Hospital of Guangzhou Medical University, Shijiazhuang Obstetrics and Gynecology Hospital | Hemorrhage, Postpartum, Placenta Previa | 02/25 | 04/25 | | |
NCT04578613: ICP-022 Versus Chlorambucil Combined With Rituximab in the Treatment of Untreated CLL/SLL |
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| Recruiting | 3 | 218 | RoW | ICP-022, Chlorambucil, Rituximab | Beijing InnoCare Pharma Tech Co., Ltd. | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | 12/24 | 06/25 | | |
| Active, not recruiting | 3 | 15374 | Europe, Canada, Japan, US, RoW | Tirzepatide, LY3298176, Placebo | Eli Lilly and Company | Obesity, Overweight | 10/27 | 10/27 | | |
NCT06083623: A Trial to Evaluate the Efficacy and Safety of TNM001 for the Prevention of Lower Respiratory Tract Infection Caused by Respiratory Syncytial Virus in Infants |
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| Not yet recruiting | 2b | 2250 | RoW | TNM001, placebo | Zhuhai Trinomab Pharmaceutical Co., Ltd. | Respiratory Syncytial Virus Infections | 05/26 | 08/26 | | |
NCT04405154: A Study of Concomitant Camrelizumab With Chemoradiation for Locally Advanced Head and Neck Cancer |
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| Not yet recruiting | 2 | 32 | NA | Camrelizumab, SHR-1210, Cisplatin, Platinol, IMRT or VMAT | West China Hospital | Head and Neck Neoplasms | 05/23 | 05/25 | | |
NCT05299697: A Study of TG103 Injection in Overweight or Obesity |
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| Recruiting | 2 | 195 | RoW | TG103 15 mg, TG103 22.5 mg, Placebo | CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. | Overweight or Obesity | 06/23 | 09/23 | | |
NCT06206720: A Study of Deuremidevir Hydrobromide for Suspension in Chinese Infants Hospitalized With RSV |
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| Recruiting | 2 | 60 | RoW | Deuremidevir Hydrobromide for Suspension, VV116, Placebo, VV116 placebo | Vigonvita Life Sciences | Respiratory Syncytial Virus Infection | 01/25 | 01/25 | | |
NCT06481085: To Evaluate Efficacy and Safety of HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus |
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| Not yet recruiting | 2 | 318 | RoW | HDM1002 50 mg, HDM1002, HDM1002 100 mg, HDM1002 200 mg, HDM1002 400 mg, HDM1002 200 mg BID, Placebo, Matching placebo for group A to group E | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Type 2 Diabetes | 04/25 | 04/25 | | |
| Active, not recruiting | 2 | 103 | Europe, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627 | Novartis Pharmaceuticals | IgA Nephropathy, Focal Segmental Glomerulosclerosis, Alport Syndrome, Diabetic Kidney Disease, Diabetic Nephropathy Type 2, Immunoglobulin A Nephropathy | 07/24 | 07/26 | | |
SKB264-II-04, NCT05816252: A Study of SKB264 for the Treatment of Participants With Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) |
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| Recruiting | 2 | 498 | Europe, RoW | SKB264, MK-2870, Pembrolizumab, MK-3475, Carboplatin, Carboplatin for injection, Osimertinib, Osimertinib Mesylate | Klus Pharma Inc., Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Non-small Cell Lung Cancer | 12/25 | 10/26 | | |
NCT05879055: A Study of PM8002 in Combination With Chemotherapy in Patients With NEN |
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| Recruiting | 2 | 60 | RoW | PM8002, FOLFIRI | Biotheus Inc. | Neuroendocrine Neoplasm | 01/27 | 01/28 | | |
NCT06106841: TQB3909 Tablets in Subjects With Relapsed or Refractory Mantle Cell Lymphoma (MCL) |
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| Recruiting | 1/2 | 39 | RoW | 400mg of TQB3909 tablets, 600mg of TQB3909 tablets | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Mantle Cell Lymphoma | 12/24 | 12/24 | | |
NCT06052813: A Study of BN104 in the Treatment of Acute Leukemia |
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| Recruiting | 1/2 | 90 | RoW | BN104 | BioNova Pharmaceuticals (Shanghai) LTD. | ALL, Adult, AML, Adult | 06/26 | 06/27 | | |
NCT05056389: Normothermic Intraperitoneal Chemotherapy - Long Term in Peritoneal Metastases From Colorectal Cancer (NIPEC-OXA) |
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| Recruiting | 1 | 20 | Europe | Oxaliplatin, Intraperitoneal catheter | Oslo University Hospital | Peritoneal Metastases, Colo-rectal Cancer | 03/23 | 06/23 | | |
| Recruiting | 1 | 76 | RoW | HS-10380, Placebo | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Schizophrenia | 06/23 | 07/23 | | |
NCT06594315: Assessing Brain Metabolism Using MRS With Deuterated Glucose |
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| Active, not recruiting | N/A | 80 | US | Deuterated Glucose, Hydrogen gas (H2) glucose, [6,6'-2H2] glucose, Magnetic Resonance Imaging (MRI), MRI, Blood Sample, MR spectroscopy (MRS), MRS | University of California, San Francisco | Glioma | 07/27 | 07/27 | | |
NCT06610604: Health-Related Quality of Life and Emotions in Patients with Thyroid Nodules |
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| Recruiting | N/A | 500 | RoW | thermal ablation, thyroidectomy | Ming-an Yu | Thyroid Nodule | 06/27 | 12/27 | | |
NCT05258461: An Innovative Smartphone Application for Adverse Event Management During Breast Cancer Adjuvant Chemotherapy |
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| Not yet recruiting | N/A | 108 | NA | use of a smartphone app for adverse event management, conventional adverse event management | Peking Union Medical College Hospital | Breast Cancer | 10/22 | 12/22 | | |
NCT03547856: A Registry Study on the "Action of Controlling Ambulatory Blood Pressure to Target in Ten Thousand Patients" |
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| Recruiting | N/A | 10000 | RoW | | Yan Li | Hypertension, Blood Pressure, Cardiovascular Diseases | 09/26 | 12/26 | | |
ASORPWICE, NCT03521739: Association of Synchronous Four-limb blOod pRessure and Pulse Wave velocIty With Cardiovascular Events |
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| Recruiting | N/A | 100000 | RoW | | Chinese Academy of Medical Sciences, Fuwai Hospital | Blood Pressure, Pulse Wave Analysis, Ankle Brachial Index, Patient Outcome Assessment | 12/22 | 12/23 | | |
| Recruiting | N/A | 4500 | RoW | | Shanghai Institute of Hypertension | Nocturnal Hypertension | 09/26 | 12/26 | | |
PROMISE, NCT04135911: A Prospective Study on The"Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting" |
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| Suspended | N/A | 2000 | RoW | | Yan Li | Hypertension, Blood Pressure | 03/26 | 03/26 | | |
NCT05535400: Effects of Physical-Psychological Integrative Intervention on SCI Patient: a Pilot Randomized Controlled Trial |
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| Completed | N/A | 72 | RoW | Physical-Psychological Integrative Intervention, Brief online didactic education | The Hong Kong Polytechnic University | Spinal Cord Injuries, Physical Inactivity, Depression, Chronic Pain | 12/22 | 07/23 | | |
| Recruiting | N/A | 60 | US | | Oregon Health and Science University, National Eye Institute (NEI) | Fuchs Dystrophy, Pseudophakic Bullous Keratopathy | 06/26 | 06/26 | | |
NCT05558657: Effect of Acupressure on Constipation in Community-dwelling Spinal Cord Injury Patients: a Randomized Controlled Trial |
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| Completed | N/A | 80 | RoW | Home-based, acupressure combined with nursing education, Home-based, manual light touch of the abdomen combined with nursing education | The Hong Kong Polytechnic University | Spinal Cord Injuries, Traditional Chinese Medicine | 09/24 | 09/24 | | |
NCT05531058: The Impact of a Web-based Psychoeducation Programme With a Motivational AI Chatbot on Covid-19 Vaccine Hesitancy |
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| Completed | N/A | 168 | RoW | AI-driven Vaccine Communicator, Self-learning of COVID-19 vaccine knowledge | The Hong Kong Polytechnic University | Vaccine Hesitancy, COVID-19 | 06/24 | 06/24 | | |
NCT01243931: Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy |
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| Recruiting | N/A | 80 | US | OCT-guided laser phototherapeutic keratectomy, Manufacturer/Name OCT Technology 510(K), Optovue/RTVue-CAM Fourier-domain K071250, Bioptigen/Bioptigen Fourier-domain K063343, Zeiss/Visante Time-domain K051789 | Oregon Health and Science University, National Eye Institute (NEI) | Corneal Opacity | 12/26 | 12/26 | | |