| Machiels, Jean-Pascal H |
JADE, NCT06256588: A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma |
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| Recruiting | 3 | 864 | Europe, Canada, Japan, US, RoW | Dostarlimab, Placebo | GlaxoSmithKline | Neoplasms, Head and Neck | 05/28 | 07/29 | | |
| Terminated | 3 | 166 | Europe, Canada, Japan, US, RoW | Xevinapant (Debio 1143), IMRT, Placebo | EMD Serono Research & Development Institute, Inc., Merck KGaA, Darmstadt, Germany | Head and Neck Cancer | 08/24 | 08/24 | | |
| Not yet recruiting | 3 | 200 | NA | Pembrolizumab, stereotattic ablation radiotherapy (SABR), SBRT | European Organisation for Research and Treatment of Cancer - EORTC, Swiss Group for Clinical Cancer Research, Merck Sharp & Dohme LLC | Oligometastatic Squamous Cell Carcinoma of the Head and Neck | 07/27 | 03/30 | | |
NCT03810872: An Explorative Study of Afatinib in the Treatment of Advanced Cancer Carrying an EGFR, a HER2 or a HER3 Mutation |
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| Recruiting | 2 | 87 | Europe | Afatinib, Paclitaxel | AZ-VUB | Cancers Harbouring an EGFR Mutation, (Excluding Non-squamous Non- Small Cell Lung Cancer, a Registered Indication), a HER2 Mutation or a HER3 Mutation | 12/20 | 12/22 | | |
| Recruiting | 2 | 17 | Europe | IO102, IO103 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain, IoBiotech ApS | Oropharynx Squamous Cell Carcinoma, Larynx Squamous Cell Carcinoma, Hypopharynx Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma | 06/24 | 06/24 | | |
| Active, not recruiting | 2 | 340 | Europe | Afatinib, Palbociclib, standard of care, IPH2201, Monalizumab, Durvalumab, Niraparib, INCAGN01876 | European Organisation for Research and Treatment of Cancer - EORTC | Carcinoma, Squamous Cell of Head and Neck | 06/25 | 12/25 | | |
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| Recruiting | 1/2 | 523 | Europe, US | MCLA-158, petosemtamab, MCLA-158 + Pembrolizumab, MCLA-158 + FOLFIRI, MCLA-158 + FOLFOX | Merus N.V., Merus N.V. | Advanced/Metastatic Solid Tumors, Colorectal Cancer, Gastric Cancer, Gastroesophageal-junction Cancer, NSCLC, HNSCC, Head and Neck Squamous Cell Carcinoma, Esophageal Cancer | 11/25 | 11/27 | | |
| Recruiting | 1/2 | 288 | Europe, US, RoW | BT5528, Nivolumab, Opdivo | BicycleTx Limited | Advanced Solid Tumor Historically Known for High EphA2 Expression, Urothelial Cancer, Ovarian Cancer, Non-small Cell Lung Cancer, Head and Neck Cancer, Triple Negative Breast Cancer, Gastric/Upper Gastrointestinal Cancer | 10/25 | 10/25 | | |
NCT05752552: Study to Determine the Safety and Pharmacokinetics of DO-2 in Patients with Advanced or Refractory Solid Tumours |
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| Recruiting | 1 | 25 | Europe | DO-2 | DeuterOncology | Adult Solid Tumor, Advanced Solid Tumor, Refractory Tumor, Non-small Cell Lung Cancer, Non-small Cell Carcinoma, Lung Cancer, Hereditary Renal Papillary Cancer | 12/25 | 12/26 | | |
CDR404-001, NCT06402201: First in Human Study of CDR404 in HLA-A*02:01 Participants with MAGE-A4 Expressing Solid Tumors |
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| Recruiting | 1 | 42 | Europe, US | CDR404 | CDR-Life AG | Select Advanced Solid Tumors | 06/26 | 12/27 | | |
CALIF, NCT03182465: Predictive Value of ProCalcitonin for the Detection of Bacteraemia in Patients Presenting to the Emergency Department for Low Risk Chemo-induced Febrile Neutropenia |
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| Terminated | N/A | 54 | Europe | Value of ProCalcitonin | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Febrile Neutropenia, Drug-Induced | 12/22 | 12/22 | | |
NCT02139020: Collection of Plasma Samples for Squamous Cell Carcinoma of the Head and Neck Patients |
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| Recruiting | N/A | 400 | Europe | Plasma samples | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Squamous Cell Carcinoma of the Head and Neck | 01/33 | 01/33 | | |
| Recruiting | N/A | 40 | Europe | Local biopsy in the tumor | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Squamous Cell Carcinoma of the Head and Neck | 12/25 | 12/25 | | |
| Recruiting | N/A | 4975 | Europe, RoW | RP-1828 IMMUcan, RP-1759 AYA/TYA, RP-1843 Arcagen, RP-1920 BioRadon | European Organisation for Research and Treatment of Cancer - EORTC | All Tumor Types | 03/26 | 03/26 | | |
| MONIOTTE, Stéphane |
| Recruiting | N/A | 10 | Europe | Focus group meetings, Individual interviews | Université Catholique de Louvain | Multiple Chronic Conditions | 12/24 | 12/24 | | |
NCT05670132: Neuro-cardiac Rehabilitation in Youth With Congenital Heart Disease (QUALINEUROREHAB) |
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| Not yet recruiting | N/A | 290 | Europe | Neurocardiac rehabilitation program, Standard of care | University Hospital, Bordeaux | Congenital Heart Disease | 04/25 | 04/25 | | |
