| Zhang, Yi |
NCT04771689: Buprenorphine/Naloxone Micro-Dosing for Postoperative Pain Management in Opioid-Tolerant Patients |
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| Not yet recruiting | 4 | 60 | US | Buprenorphine/Naloxone, Suboxone | Massachusetts General Hospital | Post-operative Pain | 12/22 | 12/22 | | |
| Recruiting | 4 | 20 | RoW | PCSK9 inhibitor （Alirocumab）plus standard medications, standard medications | Shanghai Tong Ren Hospital | Early PCSK9 Inhibitor on Ventricular Remodling | 12/24 | 06/25 | | |
NCT05292404: Impact of Early PCSK9 Inhibitor Treatment on Heart After Acute Myocardium Infarction |
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| Recruiting | 4 | 160 | RoW | alirocumab, conventional treatment | Shanghai Tong Ren Hospital, China Cardiovascular Association | Acute Myocardial Infarction | 06/25 | 12/25 | | |
NCT05003245: Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMD |
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| Recruiting | 3 | 388 | RoW | HLX04-O，recombinant anti-vascular endothelial growth factor (VEGF) humanized monoclonal antibody ophthalmic injection, Lucentis | Shanghai Henlius Biotech | Age Related Macular Degeneration | 08/23 | 03/24 | | |
nAMD, NCT05461339: TAB014 Compared to Lucentis® in Patients with Neovascular Age-related Macular Degeneration |
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| Active, not recruiting | 3 | 488 | RoW | TAB014 Monoclonal Antibody Injection, TAB014, Ranibizumab Injection [Lucentis], Lucentis | TOT Biopharm Co., Ltd., Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | Neovascular Age-related Macular Degeneration | 09/24 | 02/25 | | |
NCT06300177: D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure |
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| Recruiting | 3 | 522 | RoW | D-1553 Tablet, Docetaxel injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Non Small Cell Lung Cancer | 10/26 | 12/27 | | |
NCT06419621: PM8002 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/Metastatic Triple-negative Breast Cancer |
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| Recruiting | 3 | 360 | RoW | PM8002, Nab-Paclitaxel, Placebo | Biotheus Inc. | Triple Negative Breast Cancer(TNBC) | 07/27 | 07/28 | | |
NCT06512584: Efficacy and Safety of PJ009 in Patients with Short Bowel Syndrome Requiring Parenteral Nutrition |
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| Recruiting | 3 | 72 | RoW | PJ009, Glucagon-Like Peptide 2 (GLP-2) analogue, PJ009 Placebo, GLP-2 analogue Placebo | Chongqing Peg-Bio Biopharm Co., Ltd. | Short Bowel Syndrome | 03/26 | 04/26 | | |
RC48-C006, NCT03500380: A Study of RC48-ADC Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer With or Without Liver Metastases |
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| Active, not recruiting | 2/3 | 301 | RoW | RC48-ADC, RC48, Lapatinib, Capecitabine | RemeGen Co., Ltd. | Breast Neoplasms, Breast Diseases, Capecitabine, HER2-positive Breast Cancer, HER2 Positive Breast Carcinoma, HER2-positive Advanced Breast With Liver Metastases | 07/24 | 12/24 | | |
NCT04398940: A Study of TQ-B3139 Capsules in Subjects With MET-Altered Advanced Non-small Cell Lung Cancer |
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| Recruiting | 2 | 71 | RoW | TQ-B3139 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Non Small Cell Lung Cancer | 01/22 | 10/22 | | |
NCT06524518: A Multicenter Randomized Controlled Study of Interventional Treatment for Operable Stage Ⅱ-Ⅲ Non-small Cell Lung Cancer With Potential Recurrence as Minimal Residual Disease(MRD) Positive |
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| Not yet recruiting | 2 | 213 | RoW | Chemotherapy combined with immunization | Xuanwu Hospital, Beijing | DFS | 07/26 | 12/29 | | |
NCT03634501: Clinical Study on Anti-tumor Effect Induced by Activated Primary Natural Killer（NK）Cells |
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| Recruiting | 1/2 | 200 | RoW | Activated NK | Xuanwu Hospital, Beijing | Lung Cancer, Breast Cancer, Colon Cancer, Pancreatic Cancer, Ovarian Cancer | 09/21 | 09/22 | | |
NCT03638206: Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies |
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| Recruiting | 1/2 | 73 | RoW | CAR-T cell immunotherapy | Shenzhen BinDeBio Ltd., The First Affiliated Hospital of Zhengzhou University | B-cell Acute Lymphoblastic Leukemia, Lymphoma, Myeloid Leukemia, Multiple Myeloma, Hepatoma, Gastric Cancer, Pancreatic Cancer, Mesothelioma, Colorectal Cancer, Esophagus Cancer, Lung Cancer, Glioma, Melanoma, Synovial Sarcoma, Ovarian Cancer, Renal Carcinoma | 03/23 | 03/23 | | |
NCT05117138: Safety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors |
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| Not yet recruiting | 1/2 | 39 | RoW | AMT-116 CAR-T cells, AMT-253 CAR-T cells | Beijing Immunochina Medical Science & Technology Co., Ltd. | Melanoma, Non-small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma | 12/23 | 03/24 | | |
NCT06316791: Exploratory Clinical Study of CNCT19 Anti CD19 Cell Therapy in the Treatment of Refractory Autoimmune Diseases |
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| Recruiting | 1 | 24 | RoW | single dose of CNCT19 | Juventas Cell Therapy Ltd. | Lupus Erythematosus, Systemic | 12/24 | 12/25 | | |
NCT05122221: CRTE7A2-01 TCR-T Cell for HPV-16 Positive Advanced Cervical, Anal, or Head and Neck Cancers |
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| Recruiting | 1 | 12 | RoW | Fludarabine + Cyclophosphamide, Interleukin-2, CRTE7A2-01 TCR-T Cell | Corregene Biotechnology Co., Ltd | Cervical Cancer, Anal Cancer, Head and Neck Cancers | 03/23 | 12/24 | | |
NCT06152757: BGT007H Cells for the Treatment of Recurrent/Refractory Gastrointestinal Tumors |
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| Recruiting | 1 | 14 | RoW | First dose, Second dose, The third dose, The fourth dose | BioSyngen Pte Ltd, The First Affiliated Hospital of Zhengzhou University | Gastrointestinal Tumors | 07/25 | 07/27 | | |
NCT05381181: Safety and Efficacy Evaluation of Next-generation CD19-UCART |
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| Not yet recruiting | 1 | 20 | NA | CD19-UCART | Bioray Laboratories, The First Affiliated Hospital of Zhengzhou University | Acute Lymphoblastic Leukemia, Non Hodgkin Lymphoma | 05/24 | 05/26 | | |
NCT06077903: GT101 Injection in the Treatment of Metastatic/Recurrent Advanced Solid Tumors |
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| Recruiting | 1 | 20 | RoW | GT101 | Grit Biotechnology | Adult | 07/24 | 07/24 | | |
NCT06515626: Genetically Modified T Cells Treating Malignant Tumors |
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| Recruiting | 1 | 100 | RoW | CAR-T cell reinfusion | Yi Zhang | Solid Tumor | 12/25 | 12/27 | | |
NCT06548620: A Study of RD06-04 in Patients With Active Autoimmune Diseases |
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| Not yet recruiting | 1 | 18 | RoW | RD06-04 cell infusion | Nanjing Bioheng Biotech Co., Ltd. | SLE (Systemic Lupus), Sclerosis, ANCA Associated Vasculitis, IIM, SS, MS, NMO Spectrum Disorder, MG | 08/26 | 08/27 | | |
NCT06671236: Clinical Study of Regulatory T Cells (Tregs) in the Treatment of Neurodegenerative Diseases |
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| Recruiting | 1 | 12 | US, RoW | Autologous Human Polyclonal Regulatory T Cells Injection (NP001 Cell Injection) | Novabio Therapeutics, The First Affiliated Hospital of Zhengzhou University | Amyotrophic Lateral Sclerosis (ALS), Alzheimer's Disease(AD), Multiple System Atrophy, MSA | 12/26 | 12/27 | | |
NCT06094426: Autologous Tumor Infiltrating Lymphocyte Injection for the Treatment of Advanced Solid Tumors |
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| Recruiting | 1 | 30 | RoW | GT316 | Grit Biotechnology | Solid Tumor, Adult, GT316 | 02/26 | 02/26 | | |
NCT06560580: Ditefossol Sodium 3% Eye Drops in Patients With Dry Eye |
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| Completed | N/A | 97 | RoW | 3% Diquafosol Sodium Eye Drops | Tianjin Eye Hospital | Dry Eye Disease | 07/23 | 07/24 | | |
NCT05538429: Comparison of Analgesic Effect and Postoperative Recovery of SAPB Combined With ESPB and TPB After Thoracoscopic Surgery |
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| Recruiting | N/A | 92 | RoW | erector spinal plane combined with serratus anterior plane block, thoracic paravertebral block | Zhangyi | Thoracoscopic Surgery, Nerve Block | 10/22 | 11/22 | | |
NCT04503915: Estrogen Supplementation Mode in HRT-FET Cycle: a RCT |
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| Not yet recruiting | N/A | 784 | NA | different estrogen supplementation modes | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Hormone Replacement Therapy, Estrogen, Live Birth Rate | 11/22 | 12/23 | | |
| Recruiting | N/A | 2500 | RoW | | Xuanwu Hospital, Beijing, ChosenMed Technology (Beijing) Co.,Ltd | Non-small Cell Lung Cancer | 11/22 | 11/22 | | |
NCT06375447: Intelligent Diagnosis and Treatment Model for Insomnia Disorder |
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| Recruiting | N/A | 16000 | RoW | Routine clinical treatment | Xuanwu Hospital, Beijing, West China Hospital, Beijing Tiantan Hospital, Second Affiliated Hospital of Soochow University, Chifeng City Center Hospital Ningcheng County | Insomnia | 10/25 | 12/25 | | |
HCF-CMP-AF, NCT04127799: Integrative Management of Patients With Atrial Fibrillation Via Hospital-Community-Family-Based Telemedicine (HCFT-AF) Program |
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| Recruiting | N/A | 1000 | RoW | Hospital-Community-Family-Care Management Platform Online, Subjects with AF conventional treatment | Northern Jiangsu Province People's Hospital | Telemedicine, Atrial Fibrillation | 12/22 | 09/23 | | |
NCT05792865: A Registry Study of Patients Hospitalized With Confirmed COVID-19 |
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| Not yet recruiting | N/A | 488 | NA | paxlovid, paxlovid within initial 5 days, No paxlovid, Paxlovid, Paxlovid outside of the initial 5 days | Beijing Chao Yang Hospital | COVID-19 | 06/23 | 12/23 | | |
| Recruiting | N/A | 10 | RoW | TCR T-cells | Beijing Geekgene Technology Co., LTD | Gastric Cancer, Esophageal Cancer, Cervical Cancer, Non-Small Cell Lung Cancer NSCLC, Triple Negative Breast Cancer TNBC | 07/26 | 11/26 | | |
| Recruiting | N/A | 20 | RoW | JY231 Injection | Shenzhen Genocury Biotech Co., Ltd. | B-NHL, B-ALL | 09/26 | 12/26 | | |
NCT06133725: TAPB Combined With RSB Versus ESPB for Postoperative Analgesia After Laparoscopic Liver Resection |
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| Not yet recruiting | N/A | 60 | RoW | erector spinae plane block, transversus abdominis plane block combined with rectus sheath block | Zhangyi | Laparoscopic Hepatectomy, Nerve Block | 11/24 | 12/24 | | |
NCT06198517: Moxibustion for the Prevention of Hemorrhagic Cystitis After Allo-HSCT |
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| Recruiting | N/A | 254 | RoW | Moxibustion, Symptomatic treatment | Wuhan Union Hospital, China | Moxibustion, Hematopoietic Stem Cell Transplantation, Hemorrhagic Cystitis, Prevention | 09/25 | 12/25 | | |
| Not yet recruiting | N/A | 20 | NA | Tumor polypeptide pool induced DC-CTL cell injection | Zhengzhou Revo-Gene Technology Co., LTD, The First Affiliated Hospital of Zhengzhou University | Solid Tumor | 04/26 | 04/26 | | |
NCT06241274: Moxibustion in the Treatment of Hemorrhagic Cystitis After Allo-HSCT |
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| Recruiting | N/A | 60 | RoW | Moxibustion, Symptomatic supportive treatment | Wuhan Union Hospital, China | Moxibustion, Hematopoietic Stem Cell Transplantation, Hemorrhagic Cystitis, Treatment | 09/25 | 12/25 | | |
NCT03845088: Application of Virtual Mandibular Position in Temporomandibular Jont Reconstruction With Costochondral Graft in Children Jaw Deformity |
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| Recruiting | N/A | 15 | RoW | temporomandibular jont reconstruction with costochondral transplantation | Peking University | Temporomandibular Joint Ankylosis, Facial Asymmetry | 09/24 | 12/24 | | |
NCT06607926: Neoadjuvant With Tα1 Plus Immuno-chemotherapy for Resectable NSCLC |
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| Not yet recruiting | N/A | 40 | RoW | Thymosin Alpha 1, thymalfasin, Tislelizumab, Platinum-doublet chemotherapy | Xuanwu Hospital, Beijing | Resectable Non-Small-Cell Lung Cancer | 06/25 | 12/25 | | |
NCT03908671: Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Patients With Advanced Esophageal Cancer and Non-small Cell Lung Cancer |
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| Recruiting | N/A | 24 | RoW | Personalized mRNA Tumor Vaccine | Stemirna Therapeutics, The First Affiliated Hospital of Zhengzhou University | Esophageal Cancer, Non Small Cell Lung Cancer | 10/24 | 12/25 | | |
| Completed | N/A | 55 | US | Experimental: Locomotor Learning | VA Office of Research and Development | Aging | 06/24 | 06/24 | | |
NCT05478759: Innovative Multimodal and Attention Training to Improve Emotion Communication in Veterans With TBI and PTSD |
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| Recruiting | N/A | 20 | US | Multimodal affect recognition training, MMART, Attention Training, Brain HQ, Brain Health Workshop, BHW, National Geographic Movies, movies | VA Office of Research and Development | Brain Injury, Post Traumatic Stress Disorder | 11/25 | 12/25 | | |
NCT06658951: Anti-HER2 CAR-T Cell Injection in Patients With HER2-positive Advanced Malignant Solid Tumors |
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| Not yet recruiting | N/A | 30 | RoW | Anti-HER2 CAR-T cells | UTC Therapeutics Inc., The First Affiliated Hospital of Zhengzhou University | HER2-positive Advanced Malignant Solid Tumors | 11/26 | 11/27 | | |
NCT05308875: Efficacy and Safety Evaluation of PD1-BCMA-CART |
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| Not yet recruiting | N/A | 9 | RoW | PD1-BCMA-CART | Bioray Laboratories, The First Affiliated Hospital of Zhengzhou University | Multiple Myeloma | 01/25 | 10/25 | | |
| Recruiting | N/A | 1114 | RoW | TaTME, Transanal TME, LpTME, Laparoscopic TME | Sun Yat-sen University, Peking Union Medical College Hospital, The First Hospital of Jilin University, RenJi Hospital, Shengjing Hospital, The Second People's Hospital of Yibin, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, Nanchong Central Hospital, Zunyi Medical College, The First Affiliated Hospital of University of South China, Xinqiao Hospital, Nanfang Hospital, Southern Medical University, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, Affiliated Hospital of Guangdong Medical University, The Third Xiangya Hospital of Central South University | Rectal Neoplasms Malignant, Surgery | 07/26 | 07/26 | | |
| Recruiting | N/A | 1000 | US | MicroVention Mechanical Thrombectomy Devices as first-line treatment | Microvention-Terumo, Inc. | Acute Ischemic Stroke, Vessel Occlusion, Stroke, Ischemic | 12/25 | 12/25 | | |
NCT05380050: Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD |
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| Recruiting | N/A | 63 | US | Goal Management Training plus Attention Training, GMT + ATT, Brain Health Workshop and National Geographic Movies, BHW and National Geographic Movies | VA Office of Research and Development | Brain Injury, Cognition, PTSD, Intervention | 10/26 | 10/26 | | |
NCT05409989: MicroVention, Inc. Flow Re-Direction Endoluminal Device X (FRED™ X™) Post-Approval Study |
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| Recruiting | N/A | 154 | US | FRED™ X™, Flow Re-Direction Endoluminal Device X | Microvention-Terumo, Inc. | Intracranial Aneurysm | 09/29 | 11/29 | | |
MCBDTMIDT, NCT04817748: Metabolomics Characterization of Biomarkers of Different Types of Myocardial Infarction in Different Time. |
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| Recruiting | N/A | 40 | RoW | | Shanghai 10th People's Hospital | Myocardial Infarction | 05/21 | 05/21 | | |
NCT05146063: LNK in Polycystic Ovary Syndrome With Insulin Resistance |
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| Recruiting | N/A | 80 | RoW | Take the patient's subcutaneous fat tissue to detect the expression of LNK | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Polycystic Ovarian Syndrome, Insulin Resistance | 12/22 | 12/23 | | |
NCT04830826: A Real-world Study of Adjuvant Therapy in Early Stage NSCLC With EGFR Mutation-Positive in China |
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| Recruiting | N/A | 2000 | RoW | Surgeries | The First Affiliated Hospital of Guangzhou Medical University | NSCLC, Stage I, NSCLC, Stage II, NSCLC, Stage III | 01/24 | 07/24 | | |
NCT05593081: Multicenter Study of Fulminant Type 1 Diabetes in China |
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| Recruiting | N/A | 240 | RoW | HLA | Second Xiangya Hospital of Central South University | Diabetes Mellitus, Type 1 | 12/27 | 12/27 | | |
NCT05435898: Assessment and Digital-health Based Intervention on Subclinical Organ Damage and Cardiovascular Risk in Chinese |
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| Not yet recruiting | N/A | 4000 | RoW | | Shanghai 10th People's Hospital | Cardiovascular Diseases, Cardiovascular Morbidity, Subclinical Organ Damage, Digital Health | 09/29 | 09/29 | | |
| Jia, Wei |
NCT03299322: A Study to Assess Jia Wei Yang He Formula as a Plus Therapy in the Treatment of Persistent Asthma |
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| Recruiting | 2 | 240 | RoW | Jia Wei Yang He granule, Jia Wei Yang He Formula, Jia Wei Yang He granule Placebo, Placebo | Shanghai University of Traditional Chinese Medicine, Fudan University | Bronchial Asthma | 12/25 | 12/25 | | |
NCT06690827: Clinical Trial of CD123-targeted CAR-NK Therapy for Relapse/refractory AML or BPDCN |
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| Recruiting | 1 | 30 | RoW | Anti-CD123 CAR NK cells | Chongqing Precision Biotech Co., Ltd | AML (Acute Myeloid Leukemia), BPDCN (blastic Plasmacytoid Dendritic Cell Neoplasm) | 10/27 | 10/28 | | |
