The Aurum Institute: Pretoria Clinical Research Centre
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 1 Trial 
11 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Glover, Nicole
panTB-HM, NCT05686356: A Pan-TB Regimen Targeting Host and Microbe

Recruiting
2/3
352
RoW
Sutezolid, N-acetyl cysteine, NAC, Pretomanid, Bedaquiline, Rifafour
The Aurum Institute NPC, Ludwig-Maximilians - University of Munich, Stichting Katholieke Universiteit, Wits Health Consortium (Pty) Ltd, Instituto Nacional de Saúde, Mozambique, National Institute for Medical Research, Tanzania, University of Stellenbosch, Sequella, Inc., Global Alliance for TB Drug Development
Tuberculosis
09/25
09/25
DOLPHIN KIDS, NCT05122767: Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment

Recruiting
1/2
92
RoW
Dolutegravir, 3HP
The Aurum Institute NPC, Johns Hopkins University
Tuberculosis, HIV
12/24
12/25
Govender, Vaneshree
NCT05022212: Phase 2 Trial of LACTIN-V in Women at High Risk of HIV Acquisition

Completed
2
45
RoW
LACTIN-V, Lactobacillus crispatus CTV-05, Placebo
University of California, San Francisco, University of KwaZulu, Harvard University, Aurum Institute, Health Systems Trust, Osel, Inc., Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Bacterial Vaginosis, HIV Infections
03/23
03/23
DOLPHIN Moms, NCT05122026: Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV

Recruiting
1/2
252
RoW
Rifapentine, Priftin, Isoniazid, Winthrop Isoniazid
The Aurum Institute NPC, Johns Hopkins University, Weill Medical College of Cornell University, University of Washington
HIV Seropositivity, Pregnancy, Tuberculosis Infection
12/24
03/25
DOLPHIN KIDS, NCT05122767: Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment

Recruiting
1/2
92
RoW
Dolutegravir, 3HP
The Aurum Institute NPC, Johns Hopkins University
Tuberculosis, HIV
12/24
12/25
nTB-01, NCT06050356: First-in-Human Trial of the Novel Tuberculosis Vaccine Candidate, H107e/CAF®10b

Recruiting
1
140
RoW
H107e, CAF®10b, H107e/CAF®10b - low adjuvant dose, H107e/CAF®10b - full adjuvant dose, Low dose intranasal H107e, Full dose intranasal H107e, H107e/CAF®10b, i.m. placebo, BCG, i.d. placebo, Intranasal H107e
Statens Serum Institut, Aurum Institute, Bill and Melinda Gates Foundation, Leiden University Medical Center, South African Tuberculosis Vaccine Initiative
Healthy
05/26
05/26
Venter, Esme
AUR1-8-341, NCT05515042: Phase 2a Trial to Evaluate Safety and Immunogenicity of COVID-19 Vaccine Strategies in HIV-infected/Uninfected Adults.

Active, not recruiting
2
694
RoW
Ad26.COV2.S (VAC31518, JNJ-78436735) Vaccine, SARS-CoV-2 rS (CovovaxTM), BNT162b2 (Pfizer)
The Aurum Institute NPC, Coalition for Epidemic Preparedness Innovations
COVID-19
06/24
12/24
Zyl, Lelanie van
AUR1-8-341, NCT05515042: Phase 2a Trial to Evaluate Safety and Immunogenicity of COVID-19 Vaccine Strategies in HIV-infected/Uninfected Adults.

Active, not recruiting
2
694
RoW
Ad26.COV2.S (VAC31518, JNJ-78436735) Vaccine, SARS-CoV-2 rS (CovovaxTM), BNT162b2 (Pfizer)
The Aurum Institute NPC, Coalition for Epidemic Preparedness Innovations
COVID-19
06/24
12/24
DOLPHIN KIDS, NCT05122767: Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment

Recruiting
1/2
92
RoW
Dolutegravir, 3HP
The Aurum Institute NPC, Johns Hopkins University
Tuberculosis, HIV
12/24
12/25
Zwane, Zwelethu Desmond
AUR1-8-341, NCT05515042: Phase 2a Trial to Evaluate Safety and Immunogenicity of COVID-19 Vaccine Strategies in HIV-infected/Uninfected Adults.

Active, not recruiting
2
694
RoW
Ad26.COV2.S (VAC31518, JNJ-78436735) Vaccine, SARS-CoV-2 rS (CovovaxTM), BNT162b2 (Pfizer)
The Aurum Institute NPC, Coalition for Epidemic Preparedness Innovations
COVID-19
06/24
12/24
DOLPHIN KIDS, NCT05122767: Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment

Recruiting
1/2
92
RoW
Dolutegravir, 3HP
The Aurum Institute NPC, Johns Hopkins University
Tuberculosis, HIV
12/24
12/25

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