VA Greater Los Angeles Healthcare System Trials

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Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Ong, Michael K

TRIPLE-SWITCH, NCT06592924: Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Not yet recruiting

830

Abiraterone, Enzalutamide, Apalutamide, Darolutamide (BAY 1841788), Docetaxel, ADT

Canadian Cancer Trials Group, ECOG-ACRIN Cancer Research Group, NRG Oncology, Alliance for Clinical Trials in Oncology, SWOG Cancer Research Network

Prostate Cancer (Adenocarcinoma)

03/31

04/31

RADIANT, NCT04543110: Radiation and Durvalumab Immunotherapy As Neoadjuvant Treatment for MIBC

Recruiting

Canada

Durvalumab, (MEDI4736), Immune Modulating Radiation, Neoadjuvant Immune Modulating Radiation

Ottawa Hospital Research Institute, Cross Cancer Institute, Hamilton Health Sciences Corporation, London Health Sciences Centre, Ontario Institute for Cancer Research, AstraZeneca, Ozmosis Research Inc.

Bladder Cancer

10/23

11/24

NCT05111574: Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Recruiting

Canada, US

Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Scan, Bone Scintigraphy, Cabozantinib S-malate, BMS-907351, Cabometyx, Cometriq, XL 184, XL-184, XL184, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo, Placebo Administration, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, PT

National Cancer Institute (NCI)

Anal Melanoma, Bladder Melanoma, Cervical Melanoma, Esophageal Melanoma, Gallbladder Melanoma, Head and Neck Mucosal Melanoma, Mucosal Melanoma, Mucosal Melanoma of the Urinary System, Nasopharyngeal Mucosal Melanoma, Oral Cavity Mucosal Melanoma, Penile Mucosal Melanoma, Rectal Melanoma, Recurrent Mucosal Melanoma, Sinonasal Mucosal Melanoma, Urethral Melanoma, Vaginal Melanoma, Vulvar Melanoma

12/25

NCT03385655: Prostate Cancer Biomarker Enrichment and Treatment Selection

Active, not recruiting

200

Canada

Adavosertib, Savolitinib, Darolutamide, CFI-400945, Ipatasertib, Durvalumab and Tremelimumab, Carboplatin

Canadian Cancer Trials Group, Canadian Cancer Clinical Trials Network, BC Cancer Foundation

Prostate Cancer

06/25

12/25

NCT05174611: Vitamin D to Improve Quadricep Muscle Strength

Recruiting

RoW

Vitamin D3, Placebo

Chinese University of Hong Kong

Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear

03/28

09/29

NCT06129084: A Study to Compare the Results of FGFR Testing by Either CtDNA Blood Testing or Standard Tumor Tissue Testing

Recruiting

N/A

260

Canada

FGFR Testing

Bernie Eigl, Vancouver Prostate Centre, Lady Davis Institute, Bladder Cancer Canada

Metastatic Bladder Cancer, Metastatic Urothelial Carcinoma

03/25

05/25

NCT05693493: Can Proprioceptive Knee Brace Improve Functional Outcome Following TKA?

Recruiting

N/A

RoW

Proprioceptive knee brace

Chinese University of Hong Kong

Knee Osteoarthritis

06/24

09/24

REGENETEN, NCT04450342: ™ Bioinductive Implant System in Full-thickness Tears

Terminated

N/A

119

Europe, Canada, US, RoW

Arthroscopic rotator cuff repair with REGENETEN™ Bioinductive Implant augmentation, Arthroscopic rotator cuff repair, Arthroscopic rotator cuff repair for revision surgery

Smith & Nephew, Inc.

Rotator Cuff Injuries

10/23

NCT06181097: Routine Use of Negative Pressure Wound Therapy THR TKR RCT

Recruiting

N/A

RoW

negative pressure wound therapy, standard dressing

Chinese University of Hong Kong

Knee Arthropathy, Hip Arthropathy, Negative Pressure Wound Therapy

12/25

12/26

NCT06196567: Pulsed Electromagnetic Field Therapy on Muscle Strength and Function in Patients With End-stage of Knee Osteoarthritis

Recruiting

N/A

RoW

PEMF, exercise

Chinese University of Hong Kong

Knee Osteoarthritis

06/26

12/28

NCT05550428: The Effects of Pulsed Electromagnetic Field Therapy on Patients With End-stage of Knee Osteoarthritis

Active, not recruiting

N/A

RoW

home-based-exercise, active pulsed electromagnetic field（PEMF）therapy, shame pulsed electromagnetic field（PEMF）therapy

Chinese University of Hong Kong

Knee Osteoarthritis, Sarcopenia

06/25

NCT05548712: The Effect of PEMF for Patients With Knee OA

Recruiting

N/A

RoW

Pulse Electromagnetic Field, Sham Pulse Electromagnetic Field

Chinese University of Hong Kong

Knee Osteoarthritis, Knee Pain Chronic

09/24

NCT04868682: Addressing Insufficient PAP Use in Older Veterans

Active, not recruiting

N/A

234

Behavioral Education Intervention I, Behavioral Education Intervention II

VA Office of Research and Development

Sleep Apnea

08/25

mPAP, NCT06039865: Chronic Care Management With Wearable Devices in Patients Prescribed Positive Airway Pressure Therapy () Trial

Completed

N/A

Immediate Intervention, Waitlist control

VA Greater Los Angeles Healthcare System, University of California, Los Angeles

Obstructive Sleep Apnea

01/25

NCT05254054: The Effect of Whole Body Vibration After ACLR

Recruiting

N/A

RoW

whole body vibration, Conventional exercise training

Chinese University of Hong Kong

ACL Injury

01/25

12/25

NCT05501210: Vibration on Patellofemoral Joint Pain After ACLR

Recruiting

N/A

RoW

WBV, PEMF

Chinese University of Hong Kong

Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Patellofemoral Pain

03/25

06/25

NCT06838663: Robotic-Assisted Total Knee Arthroplasty: Cruciate-Retaining Versus Bi-Cruciate Retaining

Not yet recruiting

N/A

RoW

Robotic assisted Cruciate-Retaining (CR) TKA procedures, Robotic assisted Bi-Cruciate Retaining (BCR) TKA procedures

Chinese University of Hong Kong

Knee Osteoarthritis, Total Knee Arthroplasty

11/27

01/28

NCT05981534: The Effectiveness of Vitamin D Supplementation in Patients With End-stage Knee Osteoarthritis

Recruiting

N/A

RoW

Vitamin D, SODX Co., Ltd, Osaka, Japan, Placebo

Chinese University of Hong Kong

Vitamin D Deficiency, Sarcopenia, Knee Osteoarthritis

06/25

11/25

NCT05184023: The Effect of PEMF for Patients With Quadriceps Muscle Weakness After ACLR

Active, not recruiting

N/A

RoW

Pulse Electromagnetic Field, Sham Pulse Electromagnetic Field

Chinese University of Hong Kong

Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy

09/25

CORI RCT UKA, NCT04797897: Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Unicondylar Knee Arthroplasty (UKA) Procedures

Terminated

N/A

RoW

CORI, Conventional

Smith & Nephew, Inc.

Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Requires Correction of Functional Deformity, Fracture, Knee

09/23

02/24

IRONMAN, NCT03151629: International Registry for Men With Advanced Prostate Cancer

Recruiting

N/A

5000

Europe, Canada, US, RoW

Standard of Care

Prostate Cancer Clinical Trials Consortium

Prostate Cancer

01/31

01/32

Fung, Constance H

SWITCH, NCT03511209: Discontinuation of Hypnotics in Older Veterans

Completed

N/A

132

CBTI plus taper method A, CBTI plus taper method B

VA Office of Research and Development

Insomnia

11/23

SWITCH, NCT03687086: Sleep Without Insomnia or The Use of Chronic Hypnotics

Completed

N/A

188

Program A, Program B

University of California, Los Angeles, US Department of Veterans Affairs, Virginia Commonwealth University, National Institute on Aging (NIA)

Sleep Initiation and Maintenance Disorders

11/23

mPAP, NCT06039865: Chronic Care Management With Wearable Devices in Patients Prescribed Positive Airway Pressure Therapy () Trial

Completed

N/A

Immediate Intervention, Waitlist control

VA Greater Los Angeles Healthcare System, University of California, Los Angeles

Obstructive Sleep Apnea

01/25

MINT, NCT06110091: Multi-center Trial to Improve Nocturia and Sleep in Older Adults

Recruiting

N/A

192

Integrated Behavioral Therapy Program, Health Education Program

Atlanta VA Medical Center, VA Greater Los Angeles Healthcare System, Emory University, University of California, Los Angeles, University of California, San Francisco, University of Alabama at Birmingham

Nocturia, Insomnia

04/28

08/28

Kelly, Monica

NCT05516277: Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

Recruiting

N/A

167

Behavioral Sleep Education Intervention, General Sleep Education Intervention

University of California, Los Angeles, VA Office of Research and Development

Posttraumatic Stress Disorder, Insomnia, Cardiovascular Diseases, Metabolic Disease

03/26

03/27

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Ong, Michael K

TRIPLE-SWITCH, NCT06592924: Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Not yet recruiting

830

Abiraterone, Enzalutamide, Apalutamide, Darolutamide (BAY 1841788), Docetaxel, ADT

Canadian Cancer Trials Group, ECOG-ACRIN Cancer Research Group, NRG Oncology, Alliance for Clinical Trials in Oncology, SWOG Cancer Research Network

Prostate Cancer (Adenocarcinoma)

03/31

04/31

RADIANT, NCT04543110: Radiation and Durvalumab Immunotherapy As Neoadjuvant Treatment for MIBC

Recruiting

Canada

Durvalumab, (MEDI4736), Immune Modulating Radiation, Neoadjuvant Immune Modulating Radiation

Bladder Cancer

10/23

11/24

NCT05111574: Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Recruiting

Canada, US

Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Scan, Bone Scintigraphy, Cabozantinib S-malate, BMS-907351, Cabometyx, Cometriq, XL 184, XL-184, XL184, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo, Placebo Administration, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, PT

National Cancer Institute (NCI)

12/25

NCT03385655: Prostate Cancer Biomarker Enrichment and Treatment Selection

Active, not recruiting

200

Canada

Adavosertib, Savolitinib, Darolutamide, CFI-400945, Ipatasertib, Durvalumab and Tremelimumab, Carboplatin

Canadian Cancer Trials Group, Canadian Cancer Clinical Trials Network, BC Cancer Foundation

Prostate Cancer

06/25

12/25

NCT05174611: Vitamin D to Improve Quadricep Muscle Strength

Recruiting

RoW

Vitamin D3, Placebo

Chinese University of Hong Kong

Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear

03/28

09/29

NCT06129084: A Study to Compare the Results of FGFR Testing by Either CtDNA Blood Testing or Standard Tumor Tissue Testing

Recruiting

N/A

260

Canada

FGFR Testing

Bernie Eigl, Vancouver Prostate Centre, Lady Davis Institute, Bladder Cancer Canada

Metastatic Bladder Cancer, Metastatic Urothelial Carcinoma

03/25

05/25

NCT05693493: Can Proprioceptive Knee Brace Improve Functional Outcome Following TKA?

Recruiting

N/A

RoW

Proprioceptive knee brace

Chinese University of Hong Kong

Knee Osteoarthritis

06/24

09/24

REGENETEN, NCT04450342: ™ Bioinductive Implant System in Full-thickness Tears

Terminated

N/A

119

Europe, Canada, US, RoW

Arthroscopic rotator cuff repair with REGENETEN™ Bioinductive Implant augmentation, Arthroscopic rotator cuff repair, Arthroscopic rotator cuff repair for revision surgery

Smith & Nephew, Inc.

Rotator Cuff Injuries

10/23

NCT06181097: Routine Use of Negative Pressure Wound Therapy THR TKR RCT

Recruiting

N/A

RoW

negative pressure wound therapy, standard dressing

Chinese University of Hong Kong

Knee Arthropathy, Hip Arthropathy, Negative Pressure Wound Therapy

12/25

12/26

NCT06196567: Pulsed Electromagnetic Field Therapy on Muscle Strength and Function in Patients With End-stage of Knee Osteoarthritis

Recruiting

N/A

RoW

PEMF, exercise

Chinese University of Hong Kong

Knee Osteoarthritis

06/26

12/28

NCT05550428: The Effects of Pulsed Electromagnetic Field Therapy on Patients With End-stage of Knee Osteoarthritis

Active, not recruiting

N/A

RoW

home-based-exercise, active pulsed electromagnetic field（PEMF）therapy, shame pulsed electromagnetic field（PEMF）therapy

Chinese University of Hong Kong

Knee Osteoarthritis, Sarcopenia

06/25

NCT05548712: The Effect of PEMF for Patients With Knee OA

Recruiting

N/A

RoW

Pulse Electromagnetic Field, Sham Pulse Electromagnetic Field

Chinese University of Hong Kong

Knee Osteoarthritis, Knee Pain Chronic

09/24

NCT04868682: Addressing Insufficient PAP Use in Older Veterans

Active, not recruiting

N/A

234

Behavioral Education Intervention I, Behavioral Education Intervention II

VA Office of Research and Development

Sleep Apnea

08/25

mPAP, NCT06039865: Chronic Care Management With Wearable Devices in Patients Prescribed Positive Airway Pressure Therapy () Trial

Completed

N/A

Immediate Intervention, Waitlist control

VA Greater Los Angeles Healthcare System, University of California, Los Angeles

Obstructive Sleep Apnea

01/25

NCT05254054: The Effect of Whole Body Vibration After ACLR

Recruiting

N/A

RoW

whole body vibration, Conventional exercise training

Chinese University of Hong Kong

ACL Injury

01/25

12/25

NCT05501210: Vibration on Patellofemoral Joint Pain After ACLR

Recruiting

N/A

RoW

WBV, PEMF

Chinese University of Hong Kong

Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Patellofemoral Pain

03/25

06/25

NCT06838663: Robotic-Assisted Total Knee Arthroplasty: Cruciate-Retaining Versus Bi-Cruciate Retaining

Not yet recruiting

N/A

RoW

Robotic assisted Cruciate-Retaining (CR) TKA procedures, Robotic assisted Bi-Cruciate Retaining (BCR) TKA procedures

Chinese University of Hong Kong

Knee Osteoarthritis, Total Knee Arthroplasty

11/27

01/28

NCT05981534: The Effectiveness of Vitamin D Supplementation in Patients With End-stage Knee Osteoarthritis

Recruiting

N/A

RoW

Vitamin D, SODX Co., Ltd, Osaka, Japan, Placebo

Chinese University of Hong Kong

Vitamin D Deficiency, Sarcopenia, Knee Osteoarthritis

06/25

11/25

NCT05184023: The Effect of PEMF for Patients With Quadriceps Muscle Weakness After ACLR

Active, not recruiting

N/A

RoW

Pulse Electromagnetic Field, Sham Pulse Electromagnetic Field

Chinese University of Hong Kong

Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy

09/25

CORI RCT UKA, NCT04797897: Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Unicondylar Knee Arthroplasty (UKA) Procedures

Terminated

N/A

RoW

CORI, Conventional

Smith & Nephew, Inc.

Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Requires Correction of Functional Deformity, Fracture, Knee

09/23

02/24

IRONMAN, NCT03151629: International Registry for Men With Advanced Prostate Cancer

Recruiting

N/A

5000

Europe, Canada, US, RoW

Standard of Care

Prostate Cancer Clinical Trials Consortium

Prostate Cancer

01/31

01/32

Fung, Constance H

SWITCH, NCT03511209: Discontinuation of Hypnotics in Older Veterans

Completed

N/A

132

CBTI plus taper method A, CBTI plus taper method B

VA Office of Research and Development

Insomnia

11/23

SWITCH, NCT03687086: Sleep Without Insomnia or The Use of Chronic Hypnotics

Completed

N/A

188

Program A, Program B

University of California, Los Angeles, US Department of Veterans Affairs, Virginia Commonwealth University, National Institute on Aging (NIA)

Sleep Initiation and Maintenance Disorders

11/23

mPAP, NCT06039865: Chronic Care Management With Wearable Devices in Patients Prescribed Positive Airway Pressure Therapy () Trial

Completed

N/A

Immediate Intervention, Waitlist control

VA Greater Los Angeles Healthcare System, University of California, Los Angeles

Obstructive Sleep Apnea

01/25

MINT, NCT06110091: Multi-center Trial to Improve Nocturia and Sleep in Older Adults

Recruiting

N/A

192

Integrated Behavioral Therapy Program, Health Education Program

Nocturia, Insomnia

04/28

08/28

Kelly, Monica

NCT05516277: Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

Recruiting

N/A

167

Behavioral Sleep Education Intervention, General Sleep Education Intervention

University of California, Los Angeles, VA Office of Research and Development

Posttraumatic Stress Disorder, Insomnia, Cardiovascular Diseases, Metabolic Disease

03/26

03/27



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