D'Alessandro, Umberto |
NCT05974267: Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2) |
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| Recruiting | 2 | 192 | RoW | M5717 60 mg, Pyronaridine, Pyronaridine tetraphosphate, Atovaquone-Proguanil, M5717 200 mg, M5717 660mg | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | Malaria Infection | 04/24 | 04/24 | | |
NCT05357560: A Study to Assess the Experimental Malaria Vaccines RH5.2-VLP and R21 |
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| Recruiting | 1 | 96 | RoW | Matrix-M with RH5.2 VLP and/or R21 | University of Oxford, European and Developing Countries Clinical Trials Partnership (EDCTP), Medical Research Council Unit The Gambia at the LSHTM (MRCG) | Malaria, Plasmodium Falciparum | 07/25 | 07/25 | | |
| Recruiting | N/A | 4000 | RoW | Community Case Management, Weekly fever screening and treatment, Monthly malaria screening, MDA | London School of Hygiene and Tropical Medicine, Medical Research Council Unit, The Gambia, National Malaria Control Programme, The Gambia, Radboud University Medical Center, University of California, San Francisco, Institute for Disease Modeling | Malaria | 05/22 | 05/22 | | |
Clarke, Ed |
| Active, not recruiting | 3 | 600 | RoW | 13-valent pneumococcal conjugate vaccine [Prevenar13®] plus tetanus toxoid, PCV13, placebo 0.9% sodium chloride plus tetanus toxoid, placebo, tetanus toxoid | London School of Hygiene and Tropical Medicine, WHO Pneumococcal Serology Reference Laboratory Institute of Child Health, BUGS Bioscience London Bioscience Innovation Centre 2 Royal College Street London | Pneumonia | 02/19 | 12/20 | | |
| Active, not recruiting | 3 | 200 | RoW | meningococcal serogroup A conjugate vaccine, MenAfriVacâ„¢. | London School of Hygiene and Tropical Medicine, Public Health England, Department of State for Health and Social Welfare, The Gambia, World Health Organization, University of Cambridge, Stanford University | Meningitis, Meningococcal | 10/20 | 08/21 | | |
NCT05447377: A Study of SII Yellow Fever Vaccine to Compare Safety and Immunogenicity With STAMARIL® In Healthy Infants |
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| Recruiting | 3 | 2216 | RoW | SII Yellow Fever Vaccine, STAMARIL® | Serum Institute of India Pvt. Ltd. | Yellow Fever | 01/24 | 01/24 | | |
NCT03832049: HPV Vaccination in Africa- New Delivery Schedules Alias The HANDS HPV Vaccine Trial |
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| Active, not recruiting | 3 | 1720 | RoW | 9-valent human papillomavirus vaccine (Gardasil 9) - 3 doses, 9-valent human papillomavirus vaccine (Gardasil 9) - 2 doses, 9-valent human papillomavirus vaccine (Gardasil 9) - 1 dose | London School of Hygiene and Tropical Medicine, Public Health England, University of Cambridge, Merck Sharp & Dohme LLC | Human Papillomavirus Vaccine | 06/24 | 06/24 | | |
NCT04394689: Measles and Rubella Vaccine Microneedle Patch Phase 1-2 Age De-escalation Trial |
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| Completed | 1/2 | 281 | RoW | Measles Rubella Vaccine (MRV-SC), MRV-MNP, PLA-MNP, PLA-SC | Micron Biomedical, Inc, Medical Research Council, Centers for Disease Control and Prevention | Measles, Rubella, Vaccination, Healthy | 11/22 | 12/22 | | |