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 20 Trials 
59 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Wolfson, Aaron H
GOG-3039, NCT04393285: Abemaciclib and Letrozole to Treat Endometrial Cancer

Active, not recruiting
2
53
US
Abemaciclib, Letrozole
Gynecologic Oncology Group, Eli Lilly and Company
Endometrial Cancer
12/24
12/25
NCT05603910: Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for pMMR Recurrent/Unresectable Endometrial Carcinoma

Recruiting
1
18
US
Lenvatinib, Lenvima, Pembrolizumab, Keytruda, Hypofractionated External Beam Radiation Therapy
Aaron Wolfson
Recurrent Endometrial Carcinoma, Unresectable Endometrial Carcinoma
04/25
04/30
PROACTIVE-HF, NCT04089059: IDE Trial Heart Failure NYHA Class III

Active, not recruiting
N/A
457
Europe, US
Cordella™ Pulmonary Artery Sensor System
Endotronix, Inc.
Heart Failure NYHA Class III
04/28
04/28
Armstrong, April W
TAK-279-PsO-3003, NCT06550076: A Study of TAK-279 in Participants With Moderate-to-Severe Plaque Psoriasis

Recruiting
3
1300
Europe, Canada, Japan, US, RoW
TAK-279
Takeda
Plaque Psoriasis
05/26
05/26
NCT06088043: A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 52 Weeks of Treatment

Active, not recruiting
3
693
Europe, Canada, Japan, US, RoW
TAK-279, Placebo, Apremilast
Takeda
Plaque Psoriasis
08/25
04/26
NCT06436183: A Study of the Effects of Camoteskimab in Adults With Moderate to Severe Atopic Dermatitis

Recruiting
2
60
Canada, US
Camoteskimab, APL-9109, AVTX-007, CERC-007, AEVI-007, MEDI2338, Placebo
Apollo Therapeutics Ltd
Atopic Dermatitis, Atopic, Dermatitis, Dermatologic Disease, Eczema, Eczema Atopic Dermatitis, Eczema, Atopic
02/25
06/25
NCT05056168: Validation of a Dermatology-Specific Treatment Satisfaction Instrument

Active, not recruiting
N/A
120
US
Dermatology-Specific Treatment Satisfaction Instrument
University of Southern California, Icahn School of Medicine at Mount Sinai, Brigham and Women's Hospital
Psoriasis
03/23
12/23
LITE, NCT03726489: Light Treatment Effectiveness () Study

Completed
N/A
783
US
Daavlin 7 series 3 panel narrow band phototherapy home units, narrow band phototherapy clinic units
University of Pennsylvania, University of Utah, National Psoriasis Foundation, Patient-Centered Outcomes Research Institute
Psoriasis, Psoriatic Plaque
10/23
12/23
NCT03921944: Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty

Recruiting
N/A
30
US
CT scan of the shoulders, EMG of the shoulders
Milton S. Hershey Medical Center
Osteoarthritis of Shoulder
12/25
12/25
Pyatak, Elizabeth
REAL-T, NCT04023487: Evaluation of an Intervention for Young Adults With Diabetes: Resilient, Empowered, Active Living-Telehealth

Completed
N/A
209
US
Resilient, Empowered, Active Living-Telehealth (REAL-T)
University of Southern California, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 1
06/23
11/23
NCT06606171: Floor Sitting Study

Recruiting
N/A
40
US
Chair Sitting (30 minutes), Floor Sitting (30 minutes), Daily Floor Sitting Practice (1 month)
Beth Pyatak
Well-being/Quality of Life, Posture, Sedentary Behaviors
03/25
03/25
Katz, Michael
#HOPE4KIDNEY, NCT05820087: The HistoSonics Edison™ System for Treatment of Primary Solid Renal Tumors Using Histotripsy

Recruiting
N/A
68
US
HistoSonics Edison System, Histotripsy
HistoSonics, Inc.
Renal Cancer, Tumor, Solid, Kidney Cancer, Tumor, Tumor, Benign
07/25
05/30
Noureddin, Mazen
TRIUMPH-5, NCT06662383: A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity

Recruiting
3
800
Europe, US, RoW
Retatrutide, LY3437943, Tirzepatide, LY3298176
Eli Lilly and Company
Obesity
04/27
04/27
NATiV3, NCT04849728: A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( )

Recruiting
3
1000
Europe, Canada, US, RoW
IVA337, Lanifibranor, Placebo
Inventiva Pharma
NASH - Nonalcoholic Steatohepatitis
09/25
09/26
NAVIGATE, NCT04365868 / 2019-001983-31: Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

Active, not recruiting
2b
357
Europe, Canada, US, RoW
belapectin, GR-MD-02, galactoarabino rhamnogalacturonate, Placebo
Galectin Therapeutics Inc., Galectin Therapeutics Inc
Prevention of Esophageal Varices, NASH - Nonalcoholic Steatohepatitis, Cirrhosis
12/24
12/24
NCT05979779: Ph 2 Study of the Safety and Efficacy of Three HU6 Dose Levels and Placebo in Nonalcoholic Steatohepatitis

Active, not recruiting
2
219
US
HU6, Placebo
Rivus Pharmaceuticals, Inc.
Non-Alcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis, Fatty Liver
02/25
04/25
HORIZON, NCT05583344 / 2022-002538-14: Phase 2b Study of GSK4532990 in Adults With NASH

Active, not recruiting
2
271
Europe, Canada, Japan, US, RoW
GSK4532990, Placebo
GlaxoSmithKline, GlaxoSmithKline Research & Development Limited
Nonalcoholic Fatty Liver Disease, Non-alcoholic Fatty Liver Disease
12/25
03/26
NCT05864391: A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD7503 in Participants With Suspected NASH.

Terminated
1
40
US
AZD7503
AstraZeneca
Steatohepatitis
03/24
03/24
Chaparro, Sandra
DETECT-HF, NCT06378632: AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

Recruiting
N/A
500
Europe, US, RoW
Hearo App
Cordio Medical
Heart Failure
01/25
03/25
PROACTIVE-HF, NCT04089059: IDE Trial Heart Failure NYHA Class III

Active, not recruiting
N/A
457
Europe, US
Cordella™ Pulmonary Artery Sensor System
Endotronix, Inc.
Heart Failure NYHA Class III
04/28
04/28
NCT05934487: PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
N/A
1650
US
Cordella™ Pulmonary Artery Sensor System
Endotronix, Inc.
Heart Failure NYHA Class II, Heart Failure NYHA Class III
09/27
09/29
Qazi, Yasir
ConfIdeS, NCT04935177: Renal Function in Highly Sensitized Patients 1 Year After Desensitization With Imlifidase Prior to DD Kidney Tx

Active, not recruiting
3
64
US
Imlifidase, IdeS, HMED-IdeS, PLEX, Plasma exchange, PE, IVIg, Intravenous immunoglobulin, Anti-CD20 antibodies, Rituximab, Eculizumab, Soliris, Remain on wait list
Hansa Biopharma AB
Kidney Transplantation in Highly Sensitized Patients
06/25
06/25
ProActive, NCT04091984: The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry

Active, not recruiting
N/A
5000
US
Prospera
Natera, Inc., University of Maryland
Kidney Transplant Rejection
10/26
10/27
Yan, Pui
NCT01846663: Efficacy, Safety, And Pharmacokinetics Of Rifaximin In Subjects With Severe Hepatic Impairment And Hepatic Encephalopathy

Terminated
4
6
US
Placebo, Rifaximin, XIFAXAN® Tablets
Bausch Health Americas, Inc.
Hepatic Encephalopathy
02/16
02/16
NCT05746143: The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion

Recruiting
4
140
US
Zolpidem Tartrate 10 mg, Placebo
University of Southern California
Spine Fusion, Lumbar Spine Degeneration, Pain, Postoperative, Lumbar Spine Spondylosis
01/26
12/27
NCT05893069: Oxandrolone Multiligament Knee

Active, not recruiting
4
60
US
Oxandrolone, Placebo
George F. Hatch
Ligament Tear Knee
12/25
12/25
TOBRA, NCT04597008: Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures At High Risk of Infection:

Recruiting
3
1900
US
Treatment group, Treatment, Control group, Control
Major Extremity Trauma Research Consortium, United States Department of Defense
Post Operative Surgical Site Infection
06/25
12/26
NCT04763759: Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections

Completed
1
15
US
TRL1068, a human monoclonal antibody
Trellis Bioscience LLC, University of California, Los Angeles, Biomedical Advanced Research and Development Authority, Wellcome Trust, Sinai Hospital of Baltimore, Gulfcoast Research Institute, Phoenix Clinical Research, University of Florida, University of Alabama at Birmingham, The Methodist Hospital Research Institute, University of Virginia, University of Southern California
Prosthetic Joint Infection
03/24
03/24
MAGIC, NCT05361941: Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities

Recruiting
N/A
204
US
EP Granules with Tobramycin, empty voids
Elute, Inc.
Periprosthetic Joint Infections
12/25
12/25
SvS, NCT06586814: Suture Versus Staples for Wound Closure in Orthopaedic Trauma Surgery

Recruiting
N/A
50
US
Suture, Staple
University of Southern California
Lower Extremity Fracture
12/25
12/26
PIVOT-LC1-Pi, NCT06496867: Early Internal Fixation Versus NonOperative Care with Early Rehabilitation for LC1 Fragility Fractures of the Pelvis

Recruiting
N/A
48
US
Early Internal Fixation, Nonoperative Care with Early Rehabilitation
University of Southern California, Orthopaedic Trauma Association, McMaster University, University of Maryland, Baltimore
Multiple Closed Pelvic Fractures with Disruption of Pelvic Ring, Fragility Fracture, Internal Fixation, Nonoperative Care
12/26
12/27
NCT05876871: Stress Radiography for Pelvic Ring Injuries

Active, not recruiting
N/A
31
US
Pelvic Binder Radiography
University of Southern California
Pelvic Fracture
12/23
12/25
NCT06475365: Salt Water Gargling on Swallowing Following ACDF

Not yet recruiting
N/A
50
US
Sodium chloride gargle, Salt water gargle
University of Southern California
Degeneration Spine, Cervical Radiculopathy, Cervical Stenosis, Cervical Spondylosis, Cervical Myelopathy, Dysphagia
09/25
12/25
NCT05278494: Dextromethorphan for Treatment of Postoperative Pain

Recruiting
N/A
160
US
Dextromethorphan Hydrobromide, Placebo
Nathanael Heckmann
Post-operative Pain
12/25
12/26
NCT05592353: Effect of Post-operative Brace on Pain and Patient Outcomes Following Hip Arthroscopy for FAIS

Active, not recruiting
N/A
100
US
Brace
Alexander Weber
Hip Arthroscopy
12/26
12/26
BATON, NCT06123481: Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis

Not yet recruiting
N/A
192
US
Core Decompression, Core Decompression Procedure with Autologous Bone Marrow Aspirate Concentrate
Johns Hopkins University, Stanford University, Sinai Hospital of Baltimore, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Osteonecrosis of the Femoral Head, Avascular Necrosis of the Femoral Head
04/28
08/28
DePasquale, Eugene
NCT02670408: Diagnostic and Therapeutic Applications of Microarrays in Heart Transplantation

Recruiting
N/A
900
Europe, Canada, US, RoW
Endomyocardial biopsy
University of Alberta
Cardiac Transplant Disorder
12/25
07/26
NCT04707872: Trifecta-Heart cfDNA-MMDx Study

Recruiting
N/A
300
Europe, Canada, US, RoW
MMDx diagnostic test, Prospera, HLA antibody
University of Alberta, Natera, Inc., One Lambda
Heart Transplant Rejection
12/26
07/27
Luoto, Jill
NCT03548558: Testing Means to Scale Early Childhood Development Interventions in Rural Kenya

Completed
N/A
1152
US
Group sessions, Group+Home sessions, Booster sessions, Fathers invited
University of Southern California, Lunenfeld Tanenbaum Research Institute, Safe Water and AIDS Project (SWAP), University of California, Berkeley, McGill University, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Early Child Development
10/21
10/21
NCT06140017: Achieving Sustained Early Child Development Impacts at Scale: A Test in Kenya

Recruiting
N/A
1200
RoW
Msingi Bora responsive parenting and family wellbeing program
University of Southern California, Early Childhood Development Network for Kenya (ECDNeK), Safe Water and AIDS Project (SWAP)
Child Development, Child Behavior, Language, Child
12/25
12/25
Ramos, Melissa
SIMPLE, NCT04773392: Simplified IMmunosuppressive Protocol Utilizing Low Dose EnvarsusXR

Recruiting
4
80
US
Twice-daily Tacrolimus, Once-daily envarsus XR, Induction Immunosuppression with Basiliximab or Rabbit Anti Thymoglobulin (rATG), Methylprednisolone, prednisone, Steroids, Mycophenolate mofetil (MMF) or Mycophenolic acid (MPA), Twice a day anti-metabolite, Azathioprine, Once a day anti-metabolite
University of Southern California, Veloxis Pharmaceuticals
Kidney Transplantation, Kidney Transplant Rejection
02/25
02/25
LIMT-2, NCT05070364 / 2021-003665-35: Phase 3 Study to Evaluate the Efficacy and Safety of Peginterferon Lambda for 48 Weeks in Patients With Chronic HDV

Active, not recruiting
3
150
Europe, US, RoW
Peginterferon Lambda-1a, Lambda, Peginterferon Lambda, Pegylated Interferon Lambda
Eiger BioPharmaceuticals, Eiger BioPharmaceuticals, Inc.
Hepatitis Delta Virus
06/24
01/25
NCT02438306: CardiAMP™ Cell Therapy for Heart Failure Trial

Active, not recruiting
3
125
Canada, US
Autologous cell therapy, Sham
BioCardia, Inc.
Heart Failure, Systolic
12/24
12/26
NCT05143177: A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease with Mild to Moderate Aortic Stenosis (EVOID-AS)

Active, not recruiting
2/3
867
Canada, US
Evogliptin, DA-1229, Placebo
REDNVIA Co., Ltd.
Calcific Aortic Valve Disease
05/26
12/26
I-SPY_COVID, NCT04488081: I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients

Recruiting
2
1500
US
Remdesivir, GS-5734, Imatinib Mesylate, Dexamethasone, Cenicriviroc, Icatibant, Firazyr, Apremilast, Otezla, dornase alfa, Pulmozyme, Celecoxib, celebrex, Famotidine, Pepcid, IC14, Aviptadil, Zyesami, narsoplimab, OMS721, Cyproheptadine, periactin, Cyclosporine, CsA
QuantumLeap Healthcare Collaborative, University of California, San Francisco, University of Pennsylvania, Emory University, University of Alabama at Birmingham, University of Colorado, Denver, University of Southern California, Yale University, Wake Forest University Health Sciences, Sanford Health, Long Beach Memorial Medical Center, Georgetown University, University of California, Davis, Hoag Memorial Hospital Presbyterian, Main Line Health, DHR Health Institute for Research and Development, University of California, Irvine, Corewell Health, Kaiser Permanente, University of Michigan, West Virginia University, University of Miami, University Hospitals Cleveland Medical Center, Virtua Health, M.D. Anderson Cancer Center
COVID-19
07/28
07/30
NCT05239468 / 2022-001241-20: Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC

Active, not recruiting
2
60
US
Bezafibrate 100 mg, Bezafibrate 200 mg, Obeticholic Acid 5 mg, Obeticholic Acid placebo, Bezafibrate Placebo
Intercept Pharmaceuticals, Intercept Pharmaceuticals, Inc.
Primary Biliary Cholangitis
11/24
02/25
CALiPSO-1, NCT06255028: A Study of CNTY-101 in Participants With Refractory B Cell-mediated Autoimmune Diseases

Recruiting
1
48
US
CNTY-101, IL-2, Lymphodepleting Chemotherapy
Century Therapeutics, Inc.
Systemic Lupus Erythematosus, Lupus Nephritis, Idiopathic Inflammatory Myopathies, Diffuse Cutaneous Systemic Sclerosis
08/28
08/28
PROACTIVE-HF, NCT04089059: IDE Trial Heart Failure NYHA Class III

Active, not recruiting
N/A
457
Europe, US
Cordella™ Pulmonary Artery Sensor System
Endotronix, Inc.
Heart Failure NYHA Class III
04/28
04/28
AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) Vs Anti-Arrhythmic Drug (AAD) Therapy As a First Line Treatment for Persistent Atrial Fibrillation

Recruiting
N/A
520
Europe, Canada, US, RoW
FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone
Boston Scientific Corporation
Persistent Atrial Fibrillation
12/25
12/27
NCT04975633: USC and Bodyport Remote Heart Failure Management Study

Active, not recruiting
N/A
39
US
Bodyport Cardiac Scale
University of Southern California
Heart Failure
08/24
08/24
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis

Active, not recruiting
N/A
270
Europe, US
RheOx Bronchial Rheoplasty, Sham Procedure
Gala Therapeutics, Inc.
Chronic Bronchitis
05/24
10/25
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Recruiting
N/A
400
Europe, US, RoW
AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
Ancora Heart, Inc.
Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
12/26
12/30
AIM HIGHer, NCT05064709: Assessment of CCM in HF with Higher Ejection Fraction

Recruiting
N/A
1500
US
Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System, CCM Group (CCM ON), OPTIMIZER™ Smart Mini System, Sham Group (CCM OFF)
Impulse Dynamics
Heart Failure, Heart Failure with Preserved Ejection Fraction, Heart Failure with Mid Range Ejection Fraction, Heart Failure with Moderately Reduced Ejection Fraction, Diastolic Heart Failure
02/25
02/26
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy

Recruiting
N/A
620
US
OPTIMIZER Smart System
Impulse Dynamics
Heart Failure
03/26
03/26
NCT04502316: Real-World Experience - Barostim™ Advancing the Level of Clinical Evidence (REBALANCE Registry)

Recruiting
N/A
5000
US
Barostim™ System
CVRx, Inc.
Heart Failure
06/28
06/28
Jeon, Juyeun
ABL503-1001, NCT04762641: This is a Study to Evaluate the Safety and Tolerability of ABL503, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL503 in Subjects With Any Progressive Locally Advanced or Metastatic Solid Tumors

Recruiting
1
100
US, RoW
ABL503
ABL Bio, Inc.
Advanced Solid Tumor
06/25
06/25
Oakes, Daniel
NCT04763759: Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections

Completed
1
15
US
TRL1068, a human monoclonal antibody
Trellis Bioscience LLC, University of California, Los Angeles, Biomedical Advanced Research and Development Authority, Wellcome Trust, Sinai Hospital of Baltimore, Gulfcoast Research Institute, Phoenix Clinical Research, University of Florida, University of Alabama at Birmingham, The Methodist Hospital Research Institute, University of Virginia, University of Southern California
Prosthetic Joint Infection
03/24
03/24
MAGIC, NCT05361941: Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities

Recruiting
N/A
204
US
EP Granules with Tobramycin, empty voids
Elute, Inc.
Periprosthetic Joint Infections
12/25
12/25
Montgomery, Courtney
NCT05934487: PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
N/A
1650
US
Cordella™ Pulmonary Artery Sensor System
Endotronix, Inc.
Heart Failure NYHA Class II, Heart Failure NYHA Class III
09/27
09/29

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